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Volumn 2015, Issue , 2015, Pages

Present and future in the treatment of diabetic Kidney Disease

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALISKIREN; AMINOGUANIDINE; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIFIBROTIC AGENT; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; AST 120; BARDOXOLONE METHYL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENDOTHELIN RECEPTOR ANTAGONIST; EPLERENONE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PALOSURAN; PARICALCITOL; PENTOXIFYLLINE; PYRIDOXAMINE; RAPAMYCIN; SPIRONOLACTONE; SULODEXIDE; TRANSCRIPTION FACTOR; VITAMIN D RECEPTOR;

EID: 84928573635     PISSN: 23146745     EISSN: 23146753     Source Type: Journal    
DOI: 10.1155/2015/801348     Document Type: Review
Times cited : (39)

References (170)
  • 3
    • 73749083481 scopus 로고    scopus 로고
    • Global estimates of the prevalence of diabetes for 2010 and 2030
    • J. E. Shaw, R. A. Sicree, and P. Z. Zimmet, "Global estimates of the prevalence of diabetes for 2010 and 2030, " Diabetes Research and Clinical Practice, vol. 87, no. 1, pp. 4-14, 2010.
    • (2010) Diabetes Research and Clinical Practice , vol.87 , Issue.1 , pp. 4-14
    • Shaw, J.E.1    Sicree, R.A.2    Zimmet, P.Z.3
  • 4
    • 0036099097 scopus 로고    scopus 로고
    • Albuminuria and renal insufficiency prevalence guides population screening: Results from the NHANES III
    • A. X. Garg, B. A. Kiberd, W. F. Clark, R. B. Haynes, and C. M. Clase, "Albuminuria and renal insufficiency prevalence guides population screening: results from the NHANES III, " Kidney International, vol. 61, no. 6, pp. 2165-2175, 2002.
    • (2002) Kidney International , vol.61 , Issue.6 , pp. 2165-2175
    • Garg, A.X.1    Kiberd, B.A.2    Clark, W.F.3    Haynes, R.B.4    Clase, C.M.5
  • 5
    • 33748309114 scopus 로고    scopus 로고
    • Risk factors for renal dysfunction in type 2 diabetes: U. K. Prospective Diabetes Study 74
    • UKPDS Study Group
    • R. Retnakaran, C. A. Cull, K. I. Thorne, A. I. Adler, R. R. Holman, and UKPDS Study Group, "Risk factors for renal dysfunction in type 2 diabetes: U. K. Prospective Diabetes Study 74, " Diabetes, vol. 55, no. 6, pp. 1832-1839, 2006.
    • (2006) Diabetes , vol.55 , Issue.6 , pp. 1832-1839
    • Retnakaran, R.1    Cull, C.A.2    Thorne, K.I.3    Adler, A.I.4    Holman, R.R.5
  • 6
    • 77954280590 scopus 로고    scopus 로고
    • Development and progression of renal insufficiencywith and without albuminuria in adults with type 1 diabetes in the diabetes control and complications trial and the epidemiology of diabetes interventions and complications study
    • M. E. Molitch, M. Steffes, W. Sun et al. , "Development and progression of renal insufficiencywith and without albuminuria in adults with type 1 diabetes in the diabetes control and complications trial and the epidemiology of diabetes interventions and complications study, " Diabetes Care, vol. 33, no. 7, pp. 1536-1543, 2010.
    • (2010) Diabetes Care , vol.33 , Issue.7 , pp. 1536-1543
    • Molitch, M.E.1    Steffes, M.2    Sun, W.3
  • 7
    • 67650451498 scopus 로고    scopus 로고
    • Proteinuria as a surrogate outcome in CKD: Report of a scientific workshop sponsored by the National Kidney Foundation and the US Food and Drug Administration
    • A. S. Levey, D. Cattran, A. Friedman et al. , "Proteinuria as a surrogate outcome in CKD: report of a scientific workshop sponsored by the National Kidney Foundation and the US Food and Drug Administration, " American Journal of Kidney Diseases, vol. 54, no. 2, pp. 205-226, 2009.
    • (2009) American Journal of Kidney Diseases , vol.54 , Issue.2 , pp. 205-226
    • Levey, A.S.1    Cattran, D.2    Friedman, A.3
  • 8
    • 84860271774 scopus 로고    scopus 로고
    • Proteinuria as a surrogate end point-more data are needed
    • A. Thompson, "Proteinuria as a surrogate end point-more data are needed, " Nature Reviews Nephrology, vol. 8, no. 5, pp. 306-309, 2012.
    • (2012) Nature Reviews Nephrology , vol.8 , Issue.5 , pp. 306-309
    • Thompson, A.1
  • 9
    • 79955668545 scopus 로고    scopus 로고
    • Recognition, pathogenesis, and treatment of different stages of nephropathy in patients with type 2 diabetes mellitus
    • G. L. Bakris, "Recognition, pathogenesis, and treatment of different stages of nephropathy in patients with type 2 diabetes mellitus, " Mayo Clinic Proceedings, vol. 86, no. 5, pp. 444-456, 2011.
    • (2011) Mayo Clinic Proceedings , vol.86 , Issue.5 , pp. 444-456
    • Bakris, G.L.1
  • 10
    • 0029076841 scopus 로고
    • Effect of intensive therapy on the development and progression of diabetic nephropathy in the Diabetes Control and Complications Trial
    • DCCT/EDIC Research Group
    • DCCT/EDIC Research Group, "Effect of intensive therapy on the development and progression of diabetic nephropathy in the Diabetes Control and Complications Trial, " Kidney International, vol. 47, no. 6, pp. 1703-1720, 1995.
    • (1995) Kidney International , vol.47 , Issue.6 , pp. 1703-1720
  • 11
    • 0034628425 scopus 로고    scopus 로고
    • Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy. The diabetes control and complications trial/epidemiology of diabetes interventions and complications research group
    • DCCT/EDIC Research Group
    • DCCT/EDIC Research Group, "Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy. The diabetes control and complications trial/epidemiology of diabetes interventions and complications research group, "The New England Journal ofMedicine, vol. 342, no. 6, pp. 381-389, 2000.
    • (2000) The New England Journal OfMedicine , vol.342 , Issue.6 , pp. 381-389
  • 12
    • 45149133036 scopus 로고    scopus 로고
    • Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes
    • ADVANCE Collaborative Group
    • ADVANCE Collaborative Group, A. Patel, S. MacMahon et al. , "Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes, " The New England Journal of Medicine, vol. 358, no. 24, pp. 2560-2572, 2008.
    • (2008) The New England Journal of Medicine , vol.358 , Issue.24 , pp. 2560-2572
    • Patel, A.1    MacMahon, S.2
  • 13
    • 84855245399 scopus 로고    scopus 로고
    • Intensive diabetes therapy and glomerular filtration rate in type 1 diabetes
    • The DCCT/EDIC Research Group
    • The DCCT/EDIC Research Group, I. H. de Boer, W. Sun et al. , "Intensive diabetes therapy and glomerular filtration rate in type 1 diabetes, "The New England Journal of Medicine, vol. 365, no. 25, pp. 2366-2376, 2011.
    • (2011) The New England Journal of Medicine , vol.365 , Issue.25 , pp. 2366-2376
    • De Boer, I.H.1    Sun, W.2
  • 14
    • 84874662499 scopus 로고    scopus 로고
    • Intensive glucose control improves kidney outcomes in patients with type 2diabetes
    • V. Perkovic, H. L. Heerspink, J. Chalmers et al. , "Intensive glucose control improves kidney outcomes in patients with type 2diabetes, " Kidney International, vol. 83, no. 3, pp. 517-523, 2013.
    • (2013) Kidney International , vol.83 , Issue.3 , pp. 517-523
    • Perkovic, V.1    Heerspink, H.L.2    Chalmers, J.3
  • 15
    • 84886509566 scopus 로고    scopus 로고
    • Factors associated with microalbuminuria in 7, 549 children and adolescents with type 1 diabetes in the T1D exchange clinic registry
    • M. Daniels, S. N. Dubose, D. M. Maahs et al. , "Factors associated with microalbuminuria in 7, 549 children and adolescents with type 1 diabetes in the T1D exchange clinic registry, " Diabetes Care, vol. 36, no. 9, pp. 2639-2645, 2013.
    • (2013) Diabetes Care , vol.36 , Issue.9 , pp. 2639-2645
    • Daniels, M.1    Dubose, S.N.2    Maahs, D.M.3
  • 16
    • 84892375403 scopus 로고    scopus 로고
    • Kidney disease and related findings in the diabetes control and complications trial/epidemiology of diabetes interventions and complications study
    • DCCT/EDIC Research Group
    • I. H. de Boer and DCCT/EDIC Research Group, "Kidney disease and related findings in the diabetes control and complications trial/epidemiology of diabetes interventions and complications study, " Diabetes Care, vol. 37, no. 1, pp. 24-30, 2014.
    • (2014) Diabetes Care , vol.37 , Issue.1 , pp. 24-30
    • De Boer, I.H.1
  • 17
    • 84930465070 scopus 로고    scopus 로고
    • Standards of medical care in diabetes-2015
    • American Diabetes Association
    • American Diabetes Association, "Standards of medical care in diabetes-2015, " Diabetes Care, vol. 38, supplement 1, pp. S4-S93, 2015.
    • (2015) Diabetes Care , vol.38 , pp. S4-S93
  • 18
    • 84867497463 scopus 로고    scopus 로고
    • KDOQI clinical practice guideline for diabetes and CKD: 2012 update
    • KDOQI
    • KDOQI, "KDOQI clinical practice guideline for diabetes and CKD: 2012 update, " American Journal of Kidney Diseases, vol. 60, no. 5, pp. 850-886, 2012.
    • (2012) American Journal of Kidney Diseases , vol.60 , Issue.5 , pp. 850-886
  • 19
    • 84890476805 scopus 로고    scopus 로고
    • Linagliptin lowers albuminuria on top of recommended standard treatment in patients with type 2 diabetes and renal dysfunction
    • P.-H. Groop, M. E. Cooper, V. Perkovic, A. Emser, H.-J. Woerle, and M. von Eynatten, "Linagliptin lowers albuminuria on top of recommended standard treatment in patients with type 2 diabetes and renal dysfunction, " Diabetes Care, vol. 36, no. 11, pp. 3460-3468, 2013.
    • (2013) Diabetes Care , vol.36 , Issue.11 , pp. 3460-3468
    • Groop, P.-H.1    Cooper, M.E.2    Perkovic, V.3    Emser, A.4    Woerle, H.-J.5    Von Eynatten, M.6
  • 20
    • 84896883898 scopus 로고    scopus 로고
    • DPP-4 inhibition with alogliptin on top of angiotensin II type 1 receptor blockade ameliorates albuminuria via up-regulation of SDF-1 in type 2 diabetic patients with incipient nephropathy
    • H. Fujita, H. Taniai, H. Murayama et al. , "DPP-4 inhibition with alogliptin on top of angiotensin II type 1 receptor blockade ameliorates albuminuria via up-regulation of SDF-1 in type 2 diabetic patients with incipient nephropathy, " Endocrine Journal, vol. 61, no. 2, pp. 159-166, 2014.
    • (2014) Endocrine Journal , vol.61 , Issue.2 , pp. 159-166
    • Fujita, H.1    Taniai, H.2    Murayama, H.3
  • 21
    • 33845760213 scopus 로고    scopus 로고
    • KDOQI clinical practice guidelines and clinical practice recommendations for diabetes and chronic kidney disease
    • M. Daniels, S. N. DuBose, D. M. Maahs et al. , "KDOQI clinical practice guidelines and clinical practice recommendations for diabetes and chronic kidney disease, " American Journal of Kidney Diseases, vol. 49, supplement 2, no. 2, pp. S12-S154, 2007.
    • (2007) American Journal of Kidney Diseases , vol.49 , Issue.2 , pp. S12-S154
    • Daniels, M.1    Dubose, S.N.2    Maahs, D.M.3
  • 22
    • 84884293874 scopus 로고    scopus 로고
    • KDIGO clinical practice guideline for the management of blood pressure in chronic kidney disease
    • Kidney Disease: Improving Global Outcomes (KDIGO) Blood Pressure Work Group
    • Kidney Disease: Improving Global Outcomes (KDIGO) Blood Pressure Work Group, "KDIGO clinical practice guideline for the management of blood pressure in chronic kidney disease, " Kidney International Supplements, vol. 2, pp. 337-414, 2012.
    • (2012) Kidney International Supplements , vol.2 , pp. 337-414
  • 23
    • 77951735232 scopus 로고    scopus 로고
    • Effects of intensive blood-pressure control in type 2 diabetes mellitus
    • W. C. Cushman, G. W. Evans, R. P. Byington et al. , "Effects of intensive blood-pressure control in type 2 diabetes mellitus, " The New England Journal of Medicine, vol. 362, no. 17, pp. 1575-1585, 2010.
    • (2010) The New England Journal of Medicine , vol.362 , Issue.17 , pp. 1575-1585
    • Cushman, W.C.1    Evans, G.W.2    Byington, R.P.3
  • 24
    • 79952373965 scopus 로고    scopus 로고
    • Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes
    • H. Haller, S. Ito, J. L. Izzo Jr. et al. , "Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes, " The New England Journal of Medicine, vol. 364, no. 10, pp. 907-917, 2011.
    • (2011) The New England Journal of Medicine , vol.364 , Issue.10 , pp. 907-917
    • Haller, H.1    Ito, S.2    Izzo, J.L.3
  • 25
    • 37349101990 scopus 로고    scopus 로고
    • Obesity, diabetes, and chronic kidney disease
    • G. Eknoyan, "Obesity, diabetes, and chronic kidney disease, " Current Diabetes Reports, vol. 7, no. 6, pp. 449-453, 2007.
    • (2007) Current Diabetes Reports , vol.7 , Issue.6 , pp. 449-453
    • Eknoyan, G.1
  • 27
    • 75549089842 scopus 로고    scopus 로고
    • Obesity and changes in urine albumin/creatinine ratio in patients with type 2 diabetes: The DEMAND Study
    • M. C. E. Rossi, A. Nicolucci, F. Pellegrini et al. , "Obesity and changes in urine albumin/creatinine ratio in patients with type 2 diabetes: the DEMAND Study, " Nutrition, Metabolism and Cardiovascular Diseases, vol. 20, no. 2, pp. 110-116, 2010.
    • (2010) Nutrition, Metabolism and Cardiovascular Diseases , vol.20 , Issue.2 , pp. 110-116
    • Rossi, M.C.E.1    Nicolucci, A.2    Pellegrini, F.3
  • 29
    • 0037309569 scopus 로고    scopus 로고
    • Beneficial effects of weight loss in overweight patients with chronic proteinuric nephropathies
    • E. Morales, M. A. Valero, M. León, E. Hernández, andM. Praga, "Beneficial effects of weight loss in overweight patients with chronic proteinuric nephropathies, "AmericanJournal of Kidney Diseases, vol. 41, no. 2, pp. 319-327, 2003.
    • (2003) American Journal of Kidney Diseases , vol.41 , Issue.2 , pp. 319-327
    • Morales, E.1    Valero, M.A.2    León, M.3    Hernández, E.4    Praga, M.5
  • 31
    • 0031779392 scopus 로고    scopus 로고
    • A metaanalysis of the effects of dietary protein restriction on the rate of decline in renal function
    • B. L. Kasiske, J. D. A. Lakatua, J. Z. Ma, and T. A. Louis, "A metaanalysis of the effects of dietary protein restriction on the rate of decline in renal function, " American Journal of Kidney Diseases, vol. 31, no. 6, pp. 954-961, 1998.
    • (1998) American Journal of Kidney Diseases , vol.31 , Issue.6 , pp. 954-961
    • Kasiske, B.L.1    Lakatua, J.D.A.2    Ma, J.Z.3    Louis, T.A.4
  • 32
    • 0032972622 scopus 로고    scopus 로고
    • The effect of protein restriction on albuminuria in patients with type 2 diabetes mellitus: A randomized trial
    • L. T. J. Pijls, H. de Vries, A. J. M. Donker, and J. T. M. van Eijk, "The effect of protein restriction on albuminuria in patients with type 2 diabetes mellitus: a randomized trial, " Nephrology Dialysis Transplantation, vol. 14, no. 6, pp. 1445-1453, 1999.
    • (1999) Nephrology Dialysis Transplantation , vol.14 , Issue.6 , pp. 1445-1453
    • Pijls, L.T.J.1    De Vries, H.2    Donker, A.J.M.3    Van Eijk, J.T.M.4
  • 33
    • 0036311086 scopus 로고    scopus 로고
    • Effect of dietary protein restriction on prognosis in patients with diabetic nephropathy
    • H. P. Hansen, E. Tauber-Lassen, B. R. Jensen, and H.-H. Parving, "Effect of dietary protein restriction on prognosis in patients with diabetic nephropathy, " Kidney International, vol. 62, no. 1, pp. 220-228, 2002.
    • (2002) Kidney International , vol.62 , Issue.1 , pp. 220-228
    • Hansen, H.P.1    Tauber-Lassen, E.2    Jensen, B.R.3    Parving, H.-H.4
  • 34
    • 50049122251 scopus 로고    scopus 로고
    • Cigarette smoking and kidney dysfunction in diabetes mellitus
    • M. Cignarelli, O. Lamacchia, S. di Paolo, and L. Gesualdo, "Cigarette smoking and kidney dysfunction in diabetes mellitus, " Journal of Nephrology, vol. 21, no. 2, pp. 180-189, 2008.
    • (2008) Journal of Nephrology , vol.21 , Issue.2 , pp. 180-189
    • Cignarelli, M.1    Lamacchia, O.2    Di Paolo, S.3    Gesualdo, L.4
  • 35
    • 1242339763 scopus 로고    scopus 로고
    • Cigarette smoking exacerbates and its cessation ameliorates renal injury in type 2 diabetes
    • T. Chuahirun, J. Simoni, C. Hudson et al. , "Cigarette smoking exacerbates and its cessation ameliorates renal injury in type 2 diabetes, " American Journal of theMedical Sciences, vol. 327, no. 2, pp. 57-67, 2004.
    • (2004) American Journal of TheMedical Sciences , vol.327 , Issue.2 , pp. 57-67
    • Chuahirun, T.1    Simoni, J.2    Hudson, C.3
  • 36
    • 42249107168 scopus 로고    scopus 로고
    • Continued smoking exacerbates but cessation ameliorates progression of early type 2 diabetic nephropathy
    • K. Phisitkul, K. Hegazy, T. Chuahirun et al. , "Continued smoking exacerbates but cessation ameliorates progression of early type 2 diabetic nephropathy, " The American Journal of the Medical Sciences, vol. 335, no. 4, pp. 284-291, 2008.
    • (2008) The American Journal of the Medical Sciences , vol.335 , Issue.4 , pp. 284-291
    • Phisitkul, K.1    Hegazy, K.2    Chuahirun, T.3
  • 37
    • 2442680120 scopus 로고    scopus 로고
    • Proteinuria, a target for renoprotection in patients with type 2 diabetic nephropathy: Lessons from RENAAL
    • D. de Zeeuw, G. Remuzzi, H.-H. Parving et al. , "Proteinuria, a target for renoprotection in patients with type 2 diabetic nephropathy: lessons from RENAAL, " Kidney International, vol. 65, no. 6, pp. 2309-2320, 2004.
    • (2004) Kidney International , vol.65 , Issue.6 , pp. 2309-2320
    • De Zeeuw, D.1    Remuzzi, G.2    Parving, H.-H.3
  • 38
    • 0035922447 scopus 로고    scopus 로고
    • Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
    • E. J. Lewis, L. G. Hunsicker, W. R. Clarke et al. , "Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes, " The New England Journal of Medicine, vol. 345, no. 12, pp. 851-860, 2001.
    • (2001) The New England Journal of Medicine , vol.345 , Issue.12 , pp. 851-860
    • Lewis, E.J.1    Hunsicker, L.G.2    Clarke, W.R.3
  • 40
    • 0028860451 scopus 로고
    • The beneficial effect of angiotensin-converting enzyme inhibition with captopril on diabetic nephropathy in normotensive IDDM patients with microalbuminuria
    • L. M. B. Laffel, J. B. McGill, and D. J. Gans, "The beneficial effect of angiotensin-converting enzyme inhibition with captopril on diabetic nephropathy in normotensive IDDM patients with microalbuminuria, " The American Journal of Medicine, vol. 99, no. 5, pp. 497-504, 1995.
    • (1995) The American Journal of Medicine , vol.99 , Issue.5 , pp. 497-504
    • Laffel, L.M.B.1    McGill, J.B.2    Gans, D.J.3
  • 41
    • 84887467090 scopus 로고    scopus 로고
    • Combined angiotensin inhibition for the treatment of diabetic nephropathy
    • L. F. Fried, N. Emanuele, J. H. Zhang et al. , "Combined angiotensin inhibition for the treatment of diabetic nephropathy, " The New England Journal of Medicine, vol. 369, no. 20, pp. 1892-1903, 2013.
    • (2013) The New England Journal of Medicine , vol.369 , Issue.20 , pp. 1892-1903
    • Fried, L.F.1    Emanuele, N.2    Zhang, J.H.3
  • 42
    • 84872322085 scopus 로고    scopus 로고
    • Effect of dual blockade of the renin-angiotensin system on the progression of type 2 diabetic nephropathy: A randomized trial
    • G. Fernandez Juarez, J. Luño, V. Barrio et al. , "Effect of dual blockade of the renin-angiotensin system on the progression of type 2 diabetic nephropathy: a randomized trial, " American Journal of Kidney Diseases, vol. 61, no. 2, pp. 211-218, 2013.
    • (2013) American Journal of Kidney Diseases , vol.61 , Issue.2 , pp. 211-218
    • Fernandez Juarez, G.1    Luño, J.2    Barrio, V.3
  • 43
    • 42049107348 scopus 로고    scopus 로고
    • Telmisartan, ramipril, or both in patients at high risk for vascular events
    • ONTARGET Investigators, S. Yusuf, K. K. Teo et al. , "Telmisartan, ramipril, or both in patients at high risk for vascular events, " The New England Journal of Medicine, vol. 358, no. 15, pp. 1547-1559, 2008.
    • (2008) The New England Journal of Medicine , vol.358 , Issue.15 , pp. 1547-1559
    • ONTARGET Investigators1    Yusuf, S.2    Teo, K.K.3
  • 45
    • 84869492851 scopus 로고    scopus 로고
    • Cardiorenal end points in a trial of aliskiren for type 2 diabetes
    • H.-H. Parving, B. M. Brenner, J. J. V. McMurray et al. , "Cardiorenal end points in a trial of aliskiren for type 2 diabetes, " The New England Journal ofMedicine, vol. 367, no. 23, pp. 2204-2213, 2012.
    • (2012) The New England Journal OfMedicine , vol.367 , Issue.23 , pp. 2204-2213
    • Parving, H.-H.1    Brenner, B.M.2    McMurray, J.J.V.3
  • 47
    • 0037222490 scopus 로고    scopus 로고
    • Effectiveness of aldosterone blockade in patients with diabetic nephropathy
    • A. Sato, K. Hayashi, M. Naruse, and T. Saruta, "Effectiveness of aldosterone blockade in patients with diabetic nephropathy, " Hypertension, vol. 41, no. 1, pp. 64-68, 2003.
    • (2003) Hypertension , vol.41 , Issue.1 , pp. 64-68
    • Sato, A.1    Hayashi, K.2    Naruse, M.3    Saruta, T.4
  • 48
    • 84890086278 scopus 로고    scopus 로고
    • Long-term effects of addition of mineralocorticoid receptor antagonist to angiotensin II receptor blocker in patients with diabetic nephropathy: A randomized clinical trial
    • A. Esteghamati, S. Noshad, S. Jarrah, M. Mousavizadeh, S. H. Khoee, and M. Nakhjavani, "Long-term effects of addition of mineralocorticoid receptor antagonist to angiotensin II receptor blocker in patients with diabetic nephropathy: a randomized clinical trial, "NephrologyDialysis Transplantation, vol. 28, no. 11, pp. 2823-2833, 2013.
    • (2013) NephrologyDialysis Transplantation , vol.28 , Issue.11 , pp. 2823-2833
    • Esteghamati, A.1    Noshad, S.2    Jarrah, S.3    Mousavizadeh, M.4    Khoee, S.H.5    Nakhjavani, M.6
  • 49
    • 33750331264 scopus 로고    scopus 로고
    • Selective aldosterone blockade with eplerenone reduces albuminuria in patients with type 2 diabetes
    • M. Epstein, G. H. Williams, M. Weinberger et al. , "Selective aldosterone blockade with eplerenone reduces albuminuria in patients with type 2 diabetes, " Clinical journal of the American Society of Nephrology, vol. 1, no. 5, pp. 940-951, 2006.
    • (2006) Clinical Journal of the American Society of Nephrology , vol.1 , Issue.5 , pp. 940-951
    • Epstein, M.1    Williams, G.H.2    Weinberger, M.3
  • 50
    • 84876590155 scopus 로고    scopus 로고
    • Efficacy and safety of combined vs. Single renin-angiotensin-aldosterone system blockade in chronic kidney disease: A meta-analysis
    • P. Susantitaphong, K. Sewaralthahab, E. M. Balk, S. Eiam-Ong, N. E. Madias, and B. L. Jaber, "Efficacy and safety of combined vs. single renin-angiotensin-aldosterone system blockade in chronic kidney disease: a meta-analysis, " American Journal of Hypertension, vol. 26, no. 3, pp. 424-441, 2013.
    • (2013) American Journal of Hypertension , vol.26 , Issue.3 , pp. 424-441
    • Susantitaphong, P.1    Sewaralthahab, K.2    Balk, E.M.3    Eiam-Ong, S.4    Madias, N.E.5    Jaber, B.L.6
  • 51
    • 34249897487 scopus 로고    scopus 로고
    • Renoprotection of Optimal AntiproteinuricDoses (ROAD) study: A randomized controlled study of benazepril and losartan in chronic renal insufficiency
    • F. F. Hou, D. Xie, X. Zhang et al. , "Renoprotection of Optimal AntiproteinuricDoses (ROAD) study: a randomized controlled study of benazepril and losartan in chronic renal insufficiency, " Journal of the American Society of Nephrology, vol. 18, no. 6, pp. 1889-1898, 2007.
    • (2007) Journal of the American Society of Nephrology , vol.18 , Issue.6 , pp. 1889-1898
    • Hou, F.F.1    Xie, D.2    Zhang, X.3
  • 54
    • 58149125532 scopus 로고    scopus 로고
    • Effects of additive therapy with spironolactone on proteinuria in diabetic patients already on ACE inhibitor or ARB therapy: Results of a randomized, placebo-controlled, double-blind, crossover trial
    • M. G. Saklayen, L. K. Gyebi, J. Tasosa, and J. Yap, "Effects of additive therapy with spironolactone on proteinuria in diabetic patients already on ACE inhibitor or ARB therapy: results of a randomized, placebo-controlled, double-blind, crossover trial, " Journal of Investigative Medicine, vol. 56, no. 4, pp. 714-719, 2008.
    • (2008) Journal of Investigative Medicine , vol.56 , Issue.4 , pp. 714-719
    • Saklayen, M.G.1    Gyebi, L.K.2    Tasosa, J.3    Yap, J.4
  • 55
    • 65849248674 scopus 로고    scopus 로고
    • Effect of spironolactone therapy on albuminuria in patients with type 2 diabetes treated with angiotensinconverting enzyme inhibitors
    • M. B. Davidson, A. Wong, A. H. Hamrahian, M. Stevens, and E. S. Siraj, "Effect of spironolactone therapy on albuminuria in patients with type 2 diabetes treated with angiotensinconverting enzyme inhibitors, " Endocrine Practice, vol. 14, no. 8, pp. 985-992, 2008.
    • (2008) Endocrine Practice , vol.14 , Issue.8 , pp. 985-992
    • Davidson, M.B.1    Wong, A.2    Hamrahian, A.H.3    Stevens, M.4    Siraj, E.S.5
  • 56
    • 72049109463 scopus 로고    scopus 로고
    • Addition of angiotensin receptor blockade or mineralocorticoid antagonism to maximal angiotensin-converting enzyme inhibition in diabetic nephropathy
    • U. F. Mehdi, B. Adams-Huet, P. Raskin, G. L. Vega, and R. D. Toto, "Addition of angiotensin receptor blockade or mineralocorticoid antagonism to maximal angiotensin-converting enzyme inhibition in diabetic nephropathy, " Journal of the American Society of Nephrology, vol. 20, no. 12, pp. 2641-2650, 2009.
    • (2009) Journal of the American Society of Nephrology , vol.20 , Issue.12 , pp. 2641-2650
    • Mehdi, U.F.1    Adams-Huet, B.2    Raskin, P.3    Vega, G.L.4    Toto, R.D.5
  • 57
    • 33845302661 scopus 로고    scopus 로고
    • Long-termeffects of spironolactone on proteinuria and kidney function in patients with chronic kidney disease
    • S. Bianchi, R. Bigazzi, and V. M. Campese, "Long-termeffects of spironolactone on proteinuria and kidney function in patients with chronic kidney disease, " Kidney International, vol. 70, no. 12, pp. 2116-2123, 2006.
    • (2006) Kidney International , vol.70 , Issue.12 , pp. 2116-2123
    • Bianchi, S.1    Bigazzi, R.2    Campese, V.M.3
  • 58
    • 84874521311 scopus 로고    scopus 로고
    • Renoprotective effects of mineralocorticoid receptor blockers in patients with proteinuric kidney diseases
    • E. Morales, V. G. Millet, J. Rojas-Rivera et al. , "Renoprotective effects of mineralocorticoid receptor blockers in patients with proteinuric kidney diseases, " Nephrology Dialysis Transplantation, vol. 28, no. 2, pp. 405-412, 2013.
    • (2013) Nephrology Dialysis Transplantation , vol.28 , Issue.2 , pp. 405-412
    • Morales, E.1    Millet, V.G.2    Rojas-Rivera, J.3
  • 59
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure
    • B. Pitt, F. Zannad, W. J. Remme et al. , "The effect of spironolactone on morbidity and mortality in patients with severe heart failure, " The New England Journal of Medicine, vol. 341, no. 10, pp. 709-717, 1999.
    • (1999) The New England Journal of Medicine , vol.341 , Issue.10 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3
  • 61
    • 80755168858 scopus 로고    scopus 로고
    • Therapeutic potential ofNrf2 activators in streptozotocin-induced diabetic nephropathy
    • H. Zheng, S. A. Whitman, W. Wu et al. , "Therapeutic potential ofNrf2 activators in streptozotocin-induced diabetic nephropathy, " Diabetes, vol. 60, no. 11, pp. 3055-3066, 2011.
    • (2011) Diabetes , vol.60 , Issue.11 , pp. 3055-3066
    • Zheng, H.1    Whitman, S.A.2    Wu, W.3
  • 62
    • 54449084867 scopus 로고    scopus 로고
    • Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2-deficient mice
    • K. Yoh, A. Hirayama, K. Ishizaki et al. , "Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2-deficient mice, " Genes to Cells, vol. 13, no. 11, pp. 1159-1170, 2008.
    • (2008) Genes to Cells , vol.13 , Issue.11 , pp. 1159-1170
    • Yoh, K.1    Hirayama, A.2    Ishizaki, K.3
  • 63
    • 79960855656 scopus 로고    scopus 로고
    • Bardoxolone methyl and kidney function in CKD with type 2 diabetes
    • P. E. Pergola, P. Raskin, R. D. Toto et al. , "Bardoxolone methyl and kidney function in CKD with type 2 diabetes, " The New England Journal of Medicine, vol. 365, no. 4, pp. 327-336, 2011.
    • (2011) The New England Journal of Medicine , vol.365 , Issue.4 , pp. 327-336
    • Pergola, P.E.1    Raskin, P.2    Toto, R.D.3
  • 64
    • 84890946148 scopus 로고    scopus 로고
    • Bardoxolone methyl in type 2 diabetes and stage 4 chronic kidney disease
    • D. de Zeeuw, T. Akizawa, P. Audhya et al. , "Bardoxolone methyl in type 2 diabetes and stage 4 chronic kidney disease, " The New England Journal of Medicine, vol. 369, no. 26, pp. 2492-2503, 2013.
    • (2013) The New England Journal of Medicine , vol.369 , Issue.26 , pp. 2492-2503
    • De Zeeuw, D.1    Akizawa, T.2    Audhya, P.3
  • 65
    • 84906699232 scopus 로고    scopus 로고
    • Derivative of bardoxolone methyl, dh404, in an inverse dose-dependent manner lessens diabetes-associated atherosclerosis and improves diabetic kidney disease
    • S. M. Tan, A. Sharma, N. Stefanovic et al. , "Derivative of bardoxolone methyl, dh404, in an inverse dose-dependent manner lessens diabetes-associated atherosclerosis and improves diabetic kidney disease, " Diabetes, vol. 63, no. 9, pp. 3091-3103, 2014.
    • (2014) Diabetes , vol.63 , Issue.9 , pp. 3091-3103
    • Tan, S.M.1    Sharma, A.2    Stefanovic, N.3
  • 66
    • 84887301184 scopus 로고    scopus 로고
    • 25 (OH) vitamin D levels and renal disease progression in patients with type 2 diabetic nephropathy and blockade of the renin-angiotensin system
    • G. Fernández-Juárez, J. Luño, V. Barrio et al. , "25 (OH) vitamin D levels and renal disease progression in patients with type 2 diabetic nephropathy and blockade of the renin-angiotensin system, " Clinical Journal of the American Society of Nephrology, vol. 8, no. 11, pp. 1870-1876, 2013.
    • (2013) Clinical Journal of the American Society of Nephrology , vol.8 , Issue.11 , pp. 1870-1876
    • Fernández-Juárez, G.1    Luño, J.2    Barrio, V.3
  • 67
    • 30944467281 scopus 로고    scopus 로고
    • Vitamin D in chronic kidney disease: A systemic role for selective vitaminDreceptor activation
    • D. L. Andress, "Vitamin D in chronic kidney disease: a systemic role for selective vitaminDreceptor activation, " Kidney International, vol. 69, no. 1, pp. 33-43, 2006.
    • (2006) Kidney International , vol.69 , Issue.1 , pp. 33-43
    • Andress, D.L.1
  • 68
    • 32844466369 scopus 로고    scopus 로고
    • Antiproteinuric effect of oral paricalcitol in chronic kidney disease
    • R. Agarwal, M. Acharya, J. Tian et al. , "Antiproteinuric effect of oral paricalcitol in chronic kidney disease, " Kidney International, vol. 68, no. 6, pp. 2823-2828, 2005.
    • (2005) Kidney International , vol.68 , Issue.6 , pp. 2823-2828
    • Agarwal, R.1    Acharya, M.2    Tian, J.3
  • 69
    • 78149359262 scopus 로고    scopus 로고
    • Selective vitamin D receptor activation with paricalcitol for reduction of albuminuria in patients with type 2 diabetes (VITAL study): A randomised controlled trial
    • D. de Zeeuw, R. Agarwal, M. Amdahl et al. , "Selective vitamin D receptor activation with paricalcitol for reduction of albuminuria in patients with type 2 diabetes (VITAL study): a randomised controlled trial, " The Lancet, vol. 376, no. 9752, pp. 1543-1551, 2010.
    • (2010) The Lancet , vol.376 , Issue.9752 , pp. 1543-1551
    • De Zeeuw, D.1    Agarwal, R.2    Amdahl, M.3
  • 70
    • 66749092987 scopus 로고    scopus 로고
    • The selective vitamin D receptor activator for albuminuria lowering (VITAL) study: Study design and baseline characteristics
    • H. J. Lambers Heerspink, R. Agarwal, D. W. Coyne et al. , "The selective vitamin D receptor activator for albuminuria lowering (VITAL) study: study design and baseline characteristics, " The American Journal of Nephrology, vol. 30, no. 3, pp. 280-286, 2009.
    • (2009) The American Journal of Nephrology , vol.30 , Issue.3 , pp. 280-286
    • Lambers Heerspink, H.J.1    Agarwal, R.2    Coyne, D.W.3
  • 71
    • 84920054872 scopus 로고    scopus 로고
    • Effects of paricalcitol and aliskiren combination therapy on experimental diabetic nephropathy model in rats
    • Z. Eren, M. Y. Günal, E. A. Bakir et al. , "Effects of paricalcitol and aliskiren combination therapy on experimental diabetic nephropathy model in rats, " Kidney and Blood Pressure Research, vol. 39, no. 6, pp. 581-590, 2014.
    • (2014) Kidney and Blood Pressure Research , vol.39 , Issue.6 , pp. 581-590
    • Eren, Z.1    Günal, M.Y.2    Bakir, E.A.3
  • 73
    • 84922751530 scopus 로고    scopus 로고
    • Targeting inflammation in diabetes: Newer therapeutic options
    • N. K. Agrawal and S. Kant, "Targeting inflammation in diabetes: newer therapeutic options, " World Journal of Diabetes, vol. 5, no. 5, pp. 697-710, 2014.
    • (2014) World Journal of Diabetes , vol.5 , Issue.5 , pp. 697-710
    • Agrawal, N.K.1    Kant, S.2
  • 74
    • 33745921200 scopus 로고    scopus 로고
    • Effects of pentoxifylline on the urinary protein excretion profile of type 2 diabetic patients with microproteinuria - A double-blind, placebo-controlled randomized trial
    • M. Rodŕ?guez-Morán, G. González-González, M. V. Bermúdez-Barba et al. , "Effects of pentoxifylline on the urinary protein excretion profile of type 2 diabetic patients with microproteinuria-a double-blind, placebo-controlled randomized trial, " Clinical Nephrology, vol. 66, no. 1, pp. 3-10, 2006.
    • (2006) Clinical Nephrology , vol.66 , Issue.1 , pp. 3-10
    • Rodŕguez-Morán, M.1    González-González, G.2    Bermúdez-Barba, M.V.3
  • 75
    • 84924173941 scopus 로고    scopus 로고
    • Effect of pentoxifylline on renal function and urinary albumin excretion in patients with diabetic kidney disease: The PREDIAN trial
    • J. F. Navarro-González, C. Mora-Fernández, M. Muros de Fuentes et al. , "Effect of pentoxifylline on renal function and urinary albumin excretion in patients with diabetic kidney disease: the PREDIAN trial, " Journal of the American Society of Nephrology, vol. 26, no. 1, pp. 220-229, 2015.
    • (2015) Journal of the American Society of Nephrology , vol.26 , Issue.1 , pp. 220-229
    • Navarro-González, J.F.1    Mora-Fernández, C.2    De Muros, F.M.3
  • 76
    • 84870581145 scopus 로고    scopus 로고
    • Effects of pentoxifylline on inflammatory parameters in chronic kidney disease patients: A randomized trial
    • M. Goicoechea, S. G. de Vinuesa, B. Quiroga et al. , "Effects of pentoxifylline on inflammatory parameters in chronic kidney disease patients: a randomized trial, " Journal of Nephrology, vol. 25, no. 6, pp. 969-975, 2012.
    • (2012) Journal of Nephrology , vol.25 , Issue.6 , pp. 969-975
    • Goicoechea, M.1    De Vinuesa, S.G.2    Quiroga, B.3
  • 77
    • 79958086577 scopus 로고    scopus 로고
    • Long-term effects of fosinopril and pravastatin on cardiovascular events in subjects with microalbuminuria: Ten years of follow-up of Prevention of Renal and Vascular End-stage Disease Intervention Trial (PREVEND IT)
    • F. P. Brouwers, F. W. Asselbergs, H. L. Hillege et al. , "Long-term effects of fosinopril and pravastatin on cardiovascular events in subjects with microalbuminuria: ten years of follow-up of Prevention of Renal and Vascular End-stage Disease Intervention Trial (PREVEND IT), "The American Heart Journal, vol. 161, no. 6, pp. 1171-1178, 2011.
    • (2011) The American Heart Journal , vol.161 , Issue.6 , pp. 1171-1178
    • Brouwers, F.P.1    Asselbergs, F.W.2    Hillege, H.L.3
  • 78
    • 43049163859 scopus 로고    scopus 로고
    • Intensive lipidlowering with atorvastatin for secondaryprevention in patients after coronary artery bypass surgery
    • S. J. Shah, D. D. Waters, P. Barter et al. , "Intensive lipidlowering with atorvastatin for secondaryprevention in patients after coronary artery bypass surgery, " Journal of the American College of Cardiology, vol. 51, no. 20, pp. 1938-1943, 2008.
    • (2008) Journal of the American College of Cardiology , vol.51 , Issue.20 , pp. 1938-1943
    • Shah, S.J.1    Waters, D.D.2    Barter, P.3
  • 79
    • 72049105867 scopus 로고    scopus 로고
    • The role of the mammalian target of rapamycin (mTOR) in renal disease
    • W. Lieberthal and J. S. Levine, "The role of the mammalian target of rapamycin (mTOR) in renal disease, " Journal of the American Society of Nephrology, vol. 20, no. 12, pp. 2493-2502, 2009.
    • (2009) Journal of the American Society of Nephrology , vol.20 , Issue.12 , pp. 2493-2502
    • Lieberthal, W.1    Levine, J.S.2
  • 80
    • 0024596439 scopus 로고
    • Administration of aspirin-dipyridamole reduces proteinuria in diabetic nephropathy
    • A. H. Hopper, H. Tindall, and J. A. Davies, "Administration of aspirin-dipyridamole reduces proteinuria in diabetic nephropathy, " Nephrology Dialysis Transplantation, vol. 4, no. 2, pp. 140-143, 1989.
    • (1989) Nephrology Dialysis Transplantation , vol.4 , Issue.2 , pp. 140-143
    • Hopper, A.H.1    Tindall, H.2    Davies, J.A.3
  • 81
    • 22744459775 scopus 로고    scopus 로고
    • Endothelin-1, via ETA receptor and independently of transforming growth factor-, increases the connective tissue growth factor in vascular smooth muscle cells
    • J. Rodriguez-Vita, M. Ruiz-Ortega, M. Rupérez et al. , "Endothelin-1, via ETA receptor and independently of transforming growth factor-, increases the connective tissue growth factor in vascular smooth muscle cells, " Circulation Research, vol. 97, no. 2, pp. 125-134, 2005.
    • (2005) Circulation Research , vol.97 , Issue.2 , pp. 125-134
    • Rodriguez-Vita, J.1    Ruiz-Ortega, M.2    Rupérez, M.3
  • 82
    • 84881152296 scopus 로고    scopus 로고
    • Endothelin antagonists for diabetic and non-diabetic chronic kidney disease
    • D. E. Kohan and D. M. Pollock, "Endothelin antagonists for diabetic and non-diabetic chronic kidney disease, " British Journal of Clinical Pharmacology, vol. 76, no. 4, pp. 573-579, 2013.
    • (2013) British Journal of Clinical Pharmacology , vol.76 , Issue.4 , pp. 573-579
    • Kohan, D.E.1    Pollock, D.M.2
  • 83
    • 0029658588 scopus 로고    scopus 로고
    • An orally active ET/ET receptor antagonist ameliorates proteinuria and glomerular lesions in rats with proliferative nephritis
    • D. Gómez-Garre, R. Largo, X.-H. Liu et al. , "An orally active ET/ET receptor antagonist ameliorates proteinuria and glomerular lesions in rats with proliferative nephritis, " Kidney International, vol. 50, no. 3, pp. 962-972, 1996.
    • (1996) Kidney International , vol.50 , Issue.3 , pp. 962-972
    • Gómez-Garre, D.1    Largo, R.2    Liu, X.-H.3
  • 84
    • 84867578602 scopus 로고    scopus 로고
    • Clinical trials with endothelin receptor antagonists: What went wrong and where can we improve?
    • D. E. Kohan, J. G. Cleland, L. J. Rubin, D. Theodorescu, and M. Barton, "Clinical trials with endothelin receptor antagonists: what went wrong and where can we improve?" Life Sciences, vol. 91, no. 13-14, pp. 528-539, 2012.
    • (2012) Life Sciences , vol.91 , Issue.13-14 , pp. 528-539
    • Kohan, D.E.1    Cleland, J.G.2    Rubin, L.J.3    Theodorescu, D.4    Barton, M.5
  • 86
    • 84867418316 scopus 로고    scopus 로고
    • Clinical efficacy of the selective endothelin A receptor antagonist, atrasentan, in patients with diabetes and chronic kidney disease (CKD)
    • D. L. Andress, B. Coll, Y. Pritchett, J. Brennan, M. Molitch, and D. E. Kohan, "Clinical efficacy of the selective endothelin A receptor antagonist, atrasentan, in patients with diabetes and chronic kidney disease (CKD), " Life Sciences, vol. 91, no. 13-14, pp. 739-742, 2012.
    • (2012) Life Sciences , vol.91 , Issue.13-14 , pp. 739-742
    • Andress, D.L.1    Coll, B.2    Pritchett, Y.3    Brennan, J.4    Molitch, M.5    Kohan, D.E.6
  • 87
    • 58549084764 scopus 로고    scopus 로고
    • Hypoglycaemic, antioxidative and nephroprotective effects of taurine in alloxan diabetic rabbits
    • K. Winiarska, K. Szymanski, P. Gorniak, M. Dudziak, and J. Bryla, "Hypoglycaemic, antioxidative and nephroprotective effects of taurine in alloxan diabetic rabbits, " Biochimie, vol. 91, no. 2, pp. 261-270, 2009.
    • (2009) Biochimie , vol.91 , Issue.2 , pp. 261-270
    • Winiarska, K.1    Szymanski, K.2    Gorniak, P.3    Dudziak, M.4    Bryla, J.5
  • 89
    • 84872026139 scopus 로고    scopus 로고
    • DSaccharic acid 1, 4-lactone protects diabetic rat kidney by ameliorating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines viaNF-B andPKCsignaling
    • S. Bhattacharya, P. Manna, R. Gachhui, and P. C. Sil, "DSaccharic acid 1, 4-lactone protects diabetic rat kidney by ameliorating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines viaNF-B andPKCsignaling, " Toxicology and Applied Pharmacology, vol. 267, no. 1, pp. 16-29, 2013.
    • (2013) Toxicology and Applied Pharmacology , vol.267 , Issue.1 , pp. 16-29
    • Bhattacharya, S.1    Manna, P.2    Gachhui, R.3    Sil, P.C.4
  • 90
    • 84883419205 scopus 로고    scopus 로고
    • The antioxidant silybin prevents high glucose-induced oxidative stress and podocyte injury in vitro and in vivo
    • K. Khazim, Y. Gorin, R. C. Cavaglieri, H. E. Abboud, and P. Fanti, "The antioxidant silybin prevents high glucose-induced oxidative stress and podocyte injury in vitro and in vivo, " American Journal of Physiology-Renal Physiology, vol. 305, no. 5, pp. F691-F700, 2013.
    • (2013) American Journal of Physiology-Renal Physiology , vol.305 , Issue.5 , pp. F691-F700
    • Khazim, K.1    Gorin, Y.2    Cavaglieri, R.C.3    Abboud, H.E.4    Fanti, P.5
  • 91
    • 84891457364 scopus 로고    scopus 로고
    • Hemin therapy improves kidney function in male streptozotocin-induced diabetic rats: Role of the heme oxygenase/atrial natriuretic peptide/adiponectin axis
    • J. F. Ndisang and A. Jadhav, "Hemin therapy improves kidney function in male streptozotocin-induced diabetic rats: role of the heme oxygenase/atrial natriuretic peptide/adiponectin axis, " Endocrinology, vol. 155, no. 1, pp. 215-229, 2014.
    • (2014) Endocrinology , vol.155 , Issue.1 , pp. 215-229
    • Ndisang, J.F.1    Jadhav, A.2
  • 92
    • 84873856342 scopus 로고    scopus 로고
    • Intravenous N-acetylcysteine for prevention of contrast-induced nephropathy: A meta-analysis of randomized, controlled trials
    • Z. Sun, Q. Fu, L. Cao, W. Jin, L. Cheng, and Z. Li, "Intravenous N-acetylcysteine for prevention of contrast-induced nephropathy: a meta-analysis of randomized, controlled trials, " PLoS ONE, vol. 8, no. 1, Article ID e55124, 2013.
    • (2013) PLoS ONE , vol.8 , Issue.1
    • Sun, Z.1    Fu, Q.2    Cao, L.3    Jin, W.4    Cheng, L.5    Li, Z.6
  • 93
    • 84868704907 scopus 로고    scopus 로고
    • Effect of addition of silymarin to renin-angiotensin systeminhibitors on proteinuria in type 2 diabetic patients with overt nephropathy: A randomized, double-blind, placebo-controlled trial
    • M. K. Fallahzadeh, B. Dormanesh, M. M. Sagheb et al. , "Effect of addition of silymarin to renin-angiotensin systeminhibitors on proteinuria in type 2 diabetic patients with overt nephropathy: a randomized, double-blind, placebo-controlled trial, " American Journal of Kidney Diseases, vol. 60, no. 6, pp. 896-903, 2012.
    • (2012) American Journal of Kidney Diseases , vol.60 , Issue.6 , pp. 896-903
    • Fallahzadeh, M.K.1    Dormanesh, B.2    Sagheb, M.M.3
  • 94
    • 84855559993 scopus 로고    scopus 로고
    • Angiotensin receptor blocker andN-acetyl cysteine for reduction of proteinuria in patients with type 2 diabetesmellitus
    • S. R. Hashemi, H. Noshad, A. Tabrizi et al. , "Angiotensin receptor blocker andN-acetyl cysteine for reduction of proteinuria in patients with type 2 diabetesmellitus, " Iranian Journal of Kidney Diseases, vol. 6, no. 1, pp. 39-43, 2012.
    • (2012) Iranian Journal of Kidney Diseases , vol.6 , Issue.1 , pp. 39-43
    • Hashemi, S.R.1    Noshad, H.2    Tabrizi, A.3
  • 95
    • 84878413028 scopus 로고    scopus 로고
    • Probucol suppresses initiation of chronic hemodialysis therapy and renal dysfunctionrelated death in diabetic nephropathy patients: Sakura Study
    • K. Endo, A. Saiki, T. Yamaguchi et al. , "Probucol suppresses initiation of chronic hemodialysis therapy and renal dysfunctionrelated death in diabetic nephropathy patients: Sakura Study, " Journal ofAtherosclerosis andThrombosis, vol. 20, no. 5, pp. 494-502, 2013.
    • (2013) Journal OfAtherosclerosis AndThrombosis , vol.20 , Issue.5 , pp. 494-502
    • Endo, K.1    Saiki, A.2    Yamaguchi, T.3
  • 96
    • 29244447160 scopus 로고    scopus 로고
    • Use of allopurinol in slowing the progression of renal disease through its ability to lower serum uric acid level
    • Y.-P. Siu, K.-T. Leung, M. K.-H. Tong, and T.-H. Kwan, "Use of allopurinol in slowing the progression of renal disease through its ability to lower serum uric acid level, " American Journal of Kidney Diseases, vol. 47, no. 1, pp. 51-59, 2006.
    • (2006) American Journal of Kidney Diseases , vol.47 , Issue.1 , pp. 51-59
    • Siu, Y.-P.1    Leung, K.-T.2    Tong, M.K.-H.3    Kwan, T.-H.4
  • 98
    • 84880135111 scopus 로고    scopus 로고
    • Uric acid lowering to prevent kidney function loss in diabetes: The preventing early renal function loss (PERL) allopurinol study
    • D. M. Maahs, L. Caramori, D. Z. I. Cherney et al. , "Uric acid lowering to prevent kidney function loss in diabetes: the preventing early renal function loss (PERL) allopurinol study, " Current Diabetes Reports, vol. 13, no. 4, pp. 550-559, 2013.
    • (2013) Current Diabetes Reports , vol.13 , Issue.4 , pp. 550-559
    • Maahs, D.M.1    Caramori, L.2    Cherney, D.Z.I.3
  • 99
    • 84892395808 scopus 로고    scopus 로고
    • The effect of febuxostat to prevent a further reduction in renal function of patients with hyperuricemia who have never had gout and are complicated by chronic kidney disease stage 3: Study protocol for a multicenter randomized controlled study
    • T. Hosoya, K. Kimura, S. Itoh et al. , "The effect of febuxostat to prevent a further reduction in renal function of patients with hyperuricemia who have never had gout and are complicated by chronic kidney disease stage 3: study protocol for a multicenter randomized controlled study, " Trials, vol. 15, no. 1, article 26, 2014.
    • (2014) Trials , vol.15 , Issue.1
    • Hosoya, T.1    Kimura, K.2    Itoh, S.3
  • 100
    • 44049099969 scopus 로고    scopus 로고
    • Protein kinase C beta inhibitors: A new therapeutic target for diabetic nephropathy and vascular complications
    • S. Budhiraja and J. Singh, "Protein kinase C beta inhibitors: a new therapeutic target for diabetic nephropathy and vascular complications, " Fundamental and Clinical Pharmacology, vol. 22, no. 3, pp. 231-240, 2008.
    • (2008) Fundamental and Clinical Pharmacology , vol.22 , Issue.3 , pp. 231-240
    • Budhiraja, S.1    Singh, J.2
  • 101
    • 84887163693 scopus 로고    scopus 로고
    • Ruboxistaurin for the treatment of diabetic peripheral neuropathy: A systematic review of randomized clinical trials
    • D. Bansal, Y. Badhan, K. Gudala, and F. Schifano, "Ruboxistaurin for the treatment of diabetic peripheral neuropathy: a systematic review of randomized clinical trials, " Diabetes & Metabolism Journal, vol. 37, no. 5, pp. 375-384, 2013.
    • (2013) Diabetes & Metabolism Journal , vol.37 , Issue.5 , pp. 375-384
    • Bansal, D.1    Badhan, Y.2    Gudala, K.3    Schifano, F.4
  • 102
    • 84875430152 scopus 로고    scopus 로고
    • The effect of the Oral PKC inhibitor ruboxistaurin on vision loss in two phase 3 studies
    • M. J. Sheetz, L. P. Aiello, M. D. Davis et al. , "The effect of the Oral PKC inhibitor ruboxistaurin on vision loss in two phase 3 studies, " Investigative Ophthalmology and Visual Science, vol. 54, no. 3, pp. 1750-1757, 2013.
    • (2013) Investigative Ophthalmology and Visual Science , vol.54 , Issue.3 , pp. 1750-1757
    • Sheetz, M.J.1    Aiello, L.P.2    Davis, M.D.3
  • 104
    • 28644442122 scopus 로고    scopus 로고
    • The effect of ruboxistaurin on nephropathy in type 2 diabetes
    • K. R. Tuttle, G. L. Bakris, R. D. Toto, J. B. McGill, K. Hu, and P. W. Anderson, "The effect of ruboxistaurin on nephropathy in type 2 diabetes, " Diabetes Care, vol. 28, no. 11, pp. 2686-2690, 2005.
    • (2005) Diabetes Care , vol.28 , Issue.11 , pp. 2686-2690
    • Tuttle, K.R.1    Bakris, G.L.2    Toto, R.D.3    McGill, J.B.4    Hu, K.5    Anderson, P.W.6
  • 105
    • 84926417808 scopus 로고    scopus 로고
    • Effect of ruboxistaurin on albuminuria and estimated GFR in people with diabetic peripheral neuropathy: Results from a randomized trial
    • K. R. Tuttle, J. B. McGill, E. J. Bastyr III, K. K. Poi, N. Shahri, and P. W. Anderson, "Effect of ruboxistaurin on albuminuria and estimated GFR in people with diabetic peripheral neuropathy: results from a randomized trial, " American Journal of Kidney Diseases, vol. 65, no. 4, pp. 634-636, 2015.
    • (2015) American Journal of Kidney Diseases , vol.65 , Issue.4 , pp. 634-636
    • Tuttle, K.R.1    McGill, J.B.2    Bastyr, E.J.3    Poi, K.K.4    Shahri, N.5    Anderson, P.W.6
  • 106
    • 20544477176 scopus 로고    scopus 로고
    • Imatinib attenuates diabetic nephropathy in apolipoprotein E-knockout mice
    • M. Lassila, K. Jandeleit-Dahm, K. K. Seah et al. , "Imatinib attenuates diabetic nephropathy in apolipoprotein E-knockout mice, " Journal of theAmerican Society of Nephrology, vol. 16, no. 2, pp. 367-373, 2005.
    • (2005) Journal of TheAmerican Society of Nephrology , vol.16 , Issue.2 , pp. 367-373
    • Lassila, M.1    Jandeleit-Dahm, K.2    Seah, K.K.3
  • 108
    • 84877940478 scopus 로고    scopus 로고
    • Protective effect of short-term genistein supplementation on the early stage in diabetes-induced renal damage
    • M. J. Kim and Y. Lim, "Protective effect of short-term genistein supplementation on the early stage in diabetes-induced renal damage, " Mediators of Inflammation, vol. 2013, Article ID 510212, 14 pages, 2013.
    • (2013) Mediators of Inflammation , vol.2013
    • Kim, M.J.1    Lim, Y.2
  • 109
    • 84886822022 scopus 로고    scopus 로고
    • Inhibition of src kinase blocks high glucose-induced EGFR transactivation and collagen synthesis in mesangial cells and prevents diabetic nephropathy in mice
    • K. Taniguchi, L. Xia, H. J. Goldberg et al. , "Inhibition of src kinase blocks high glucose-induced EGFR transactivation and collagen synthesis in mesangial cells and prevents diabetic nephropathy in mice, " Diabetes, vol. 62, no. 11, pp. 3874-3886, 2013.
    • (2013) Diabetes , vol.62 , Issue.11 , pp. 3874-3886
    • Taniguchi, K.1    Xia, L.2    Goldberg, H.J.3
  • 110
    • 40949137434 scopus 로고    scopus 로고
    • Targeting of RhoA/ROCKsignalingameliorates progression of diabetic nephropathy independent of glucose control
    • V. Kolavennu, L. Zeng, H. Peng, Y. Wang, and F. R. Danesh, "Targeting of RhoA/ROCKsignalingameliorates progression of diabetic nephropathy independent of glucose control, " Diabetes, vol. 57, no. 3, pp. 714-723, 2008.
    • (2008) Diabetes , vol.57 , Issue.3 , pp. 714-723
    • Kolavennu, V.1    Zeng, L.2    Peng, H.3    Wang, Y.4    Danesh, F.R.5
  • 111
    • 84884680414 scopus 로고    scopus 로고
    • Rho kinase inhibition in diabetic kidney disease
    • R. Komers, "Rho kinase inhibition in diabetic kidney disease, " British Journal of Clinical Pharmacology, vol. 76, no. 4, pp. 551-559, 2013.
    • (2013) British Journal of Clinical Pharmacology , vol.76 , Issue.4 , pp. 551-559
    • Komers, R.1
  • 112
    • 84879999943 scopus 로고    scopus 로고
    • Fasudil inhibits epithelial-myofibroblast transdifferentiation of human renal tubular epithelialHK-2 cells induced by high glucose
    • L. Gu, Q. Gao, L. Ni, M. Wang, and F. Shen, "Fasudil inhibits epithelial-myofibroblast transdifferentiation of human renal tubular epithelialHK-2 cells induced by high glucose, " Chemical and Pharmaceutical Bulletin, vol. 61, no. 7, pp. 688-694, 2013.
    • (2013) Chemical and Pharmaceutical Bulletin , vol.61 , Issue.7 , pp. 688-694
    • Gu, L.1    Gao, Q.2    Ni, L.3    Wang, M.4    Shen, F.5
  • 113
    • 52449109519 scopus 로고    scopus 로고
    • FR167653 inhibits fibronectin expression and apoptosis in diabetic glomeruli and in high-glucose-stimulated mesangial cells
    • D.-S. Jung, J. J. Li, S.-J. Kwak et al. , "FR167653 inhibits fibronectin expression and apoptosis in diabetic glomeruli and in high-glucose-stimulated mesangial cells, " American Journal of Physiology-Renal Physiology, vol. 295, no. 2, pp. F595-F604, 2008.
    • (2008) American Journal of Physiology-Renal Physiology , vol.295 , Issue.2 , pp. F595-F604
    • Jung, D.-S.1    Li, J.J.2    Kwak, S.-J.3
  • 114
    • 84859340721 scopus 로고    scopus 로고
    • Inhibition of the p38 MAPK pathway ameliorates renal fibrosis in an NPHP2 mouse model
    • N. Sugiyama, M. Kohno, and T. Yokoyama, "Inhibition of the p38 MAPK pathway ameliorates renal fibrosis in an NPHP2 mouse model, " Nephrology Dialysis Transplantation, vol. 27, no. 4, pp. 1351-1358, 2012.
    • (2012) Nephrology Dialysis Transplantation , vol.27 , Issue.4 , pp. 1351-1358
    • Sugiyama, N.1    Kohno, M.2    Yokoyama, T.3
  • 115
    • 84863172385 scopus 로고    scopus 로고
    • The reno-protective effect of a phosphoinositide 3-kinase inhibitor wortmannin on streptozotocin-induced proteinuric renal disease rats
    • S.-H. Kim, Y.-W. Jang, P. Hwang, H.-J. Kim, G.-Y. Han, and C.-W. Kim, "The reno-protective effect of a phosphoinositide 3-kinase inhibitor wortmannin on streptozotocin-induced proteinuric renal disease rats, " Experimental and Molecular Medicine, vol. 44, no. 1, pp. 45-51, 2012.
    • (2012) Experimental and Molecular Medicine , vol.44 , Issue.1 , pp. 45-51
    • Kim, S.-H.1    Jang, Y.-W.2    Hwang, P.3    Kim, H.-J.4    Han, G.-Y.5    Kim, C.-W.6
  • 116
    • 84872170692 scopus 로고    scopus 로고
    • Selective pharmacological inhibition of phosphoinositide 3-kinase p110delta opposes the progression of autoimmune diabetes in non-obese diabetic (NOD) mice
    • C. A. Durand, M. J. Richer, K. Brenker et al. , "Selective pharmacological inhibition of phosphoinositide 3-kinase p110delta opposes the progression of autoimmune diabetes in non-obese diabetic (NOD) mice, " Autoimmunity, vol. 46, no. 1, pp. 62-73, 2013.
    • (2013) Autoimmunity , vol.46 , Issue.1 , pp. 62-73
    • Durand, C.A.1    Richer, M.J.2    Brenker, K.3
  • 117
    • 84916229097 scopus 로고    scopus 로고
    • AS101 prevents diabetic nephropathy progression and mesangial cell dysfunction: Regulation of the AKT downstream pathway
    • I. I. Shemesh, B. Rozen-Zvi, Y. Kalechman, U. Gafter, B. Sredni, and G. Drossopoulou, "AS101 prevents diabetic nephropathy progression and mesangial cell dysfunction: regulation of the AKT downstream pathway, " PLoS ONE, vol. 9, no. 12, 2014.
    • (2014) PLoS ONE , vol.9 , Issue.12
    • Shemesh, I.I.1    Rozen-Zvi, B.2    Kalechman, Y.3    Gafter, U.4    Sredni, B.5    Drossopoulou, G.6
  • 118
    • 84858008133 scopus 로고    scopus 로고
    • Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis
    • H. Sugimoto, V. S. LeBleu, D. Bosukonda et al. , "Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis, " Nature Medicine, vol. 18, no. 3, pp. 396-404, 2012.
    • (2012) Nature Medicine , vol.18 , Issue.3 , pp. 396-404
    • Sugimoto, H.1    Lebleu, V.S.2    Bosukonda, D.3
  • 121
    • 33244487764 scopus 로고    scopus 로고
    • Renoprotective effect of a dopamine D3 receptor antagonist in experimental type II diabetes
    • M.-L. P. Gross, A. Koch, B. Mühlbauer et al. , "Renoprotective effect of a dopamine D3 receptor antagonist in experimental type II diabetes, " Laboratory Investigation, vol. 86, no. 3, pp. 262-274, 2006.
    • (2006) Laboratory Investigation , vol.86 , Issue.3 , pp. 262-274
    • Gross, M.-L.P.1    Koch, A.2    Mühlbauer, B.3
  • 122
    • 0036837092 scopus 로고    scopus 로고
    • Sarpogrelate hydrochloride, a serotonin2A receptor antagonist, reduces albuminuria in diabetic patients with early-stage diabetic nephropathy
    • T. Takahashi, M. Yano, J. Minami et al. , "Sarpogrelate hydrochloride, a serotonin2A receptor antagonist, reduces albuminuria in diabetic patients with early-stage diabetic nephropathy, " Diabetes Research and Clinical Practice, vol. 58, no. 2, pp. 123-129, 2002.
    • (2002) Diabetes Research and Clinical Practice , vol.58 , Issue.2 , pp. 123-129
    • Takahashi, T.1    Yano, M.2    Minami, J.3
  • 123
    • 42549157467 scopus 로고    scopus 로고
    • Reduced albuminuria with sarpogrelate is accompanied by a decrease in monocyte chemoattractant protein-1 levels in type 2 diabetes
    • S. Ogawa, T. Mori, K. Nako, T. Ishizuka, and S. Ito, "Reduced albuminuria with sarpogrelate is accompanied by a decrease in monocyte chemoattractant protein-1 levels in type 2 diabetes, " Clinical Journal of the American Society of Nephrology, vol. 3, no. 2, pp. 362-368, 2008.
    • (2008) Clinical Journal of the American Society of Nephrology , vol.3 , Issue.2 , pp. 362-368
    • Ogawa, S.1    Mori, T.2    Nako, K.3    Ishizuka, T.4    Ito, S.5
  • 124
    • 84884830390 scopus 로고    scopus 로고
    • Advanced diabetic nephropathy with nephrotic range proteinuria: A pilot study of the long-term efficacy of subcutaneous ACTH gel on proteinuria, progression of CKD, and urinary levels of VEGF and MCP-1
    • J. A. Tumlin, C. M. Galphin, and B. H. Rovin, "Advanced diabetic nephropathy with nephrotic range proteinuria: a pilot study of the long-term efficacy of subcutaneous ACTH gel on proteinuria, progression of CKD, and urinary levels of VEGF and MCP-1, " Journal of Diabetes Research, vol. 2013, Article ID 489869, 8 pages, 2013.
    • (2013) Journal of Diabetes Research , vol.2013
    • Tumlin, J.A.1    Galphin, C.M.2    Rovin, B.H.3
  • 126
    • 84893428715 scopus 로고    scopus 로고
    • Apelin inhibits the development of diabetic nephropathy by regulating histone acetylation in Akita mouse
    • H. Chen, J. Li, L. Jiao et al. , "Apelin inhibits the development of diabetic nephropathy by regulating histone acetylation in Akita mouse, " The Journal of Physiology, vol. 592, part 3, pp. 505-521, 2014.
    • (2014) The Journal of Physiology , vol.592 , pp. 505-521
    • Chen, H.1    Li, J.2    Jiao, L.3
  • 127
    • 84863278229 scopus 로고    scopus 로고
    • Exogenous activated protein C inhibits the progression of diabetic nephropathy
    • P. Gil-Bernabe, C. N. D'Alessandro-Gabazza, M. Toda et al. , "Exogenous activated protein C inhibits the progression of diabetic nephropathy, " Journal of Thrombosis and Haemostasis, vol. 10, no. 3, pp. 337-346, 2012.
    • (2012) Journal of Thrombosis and Haemostasis , vol.10 , Issue.3 , pp. 337-346
    • Gil-Bernabe, P.1    D'Alessandro-Gabazza, C.N.2    Toda, M.3
  • 128
    • 80052897170 scopus 로고    scopus 로고
    • Protective role of cannabinoid receptor type 2 in a mouse model of diabetic nephropathy
    • F. Barutta, F. Piscitelli, S. Pinach et al. , "Protective role of cannabinoid receptor type 2 in a mouse model of diabetic nephropathy, " Diabetes, vol. 60, no. 9, pp. 2386-2396, 2011.
    • (2011) Diabetes , vol.60 , Issue.9 , pp. 2386-2396
    • Barutta, F.1    Piscitelli, F.2    Pinach, S.3
  • 129
    • 84863116720 scopus 로고    scopus 로고
    • Blockade of cannabinoid receptor 1 improves insulin resistance, lipid metabolism, and diabetic nephropathy in db/db mice
    • D. H. Nam, M. H. Lee, J. E. Kimet al. , "Blockade of cannabinoid receptor 1 improves insulin resistance, lipid metabolism, and diabetic nephropathy in db/db mice, " Endocrinology, vol. 153, no. 3, pp. 1387-1396, 2012.
    • (2012) Endocrinology , vol.153 , Issue.3 , pp. 1387-1396
    • Nam, D.H.1    Lee, J.E.2    Kimet, M.H.3
  • 130
    • 84867351598 scopus 로고    scopus 로고
    • Can existing drugs approved for other indications retard renal function decline in patients with type 1 diabetes and nephropathy?
    • A. Doria, M. A. Niewczas, and P. Fiorina, "Can existing drugs approved for other indications retard renal function decline in patients with type 1 diabetes and nephropathy?" Seminars in Nephrology, vol. 32, no. 5, pp. 437-444, 2012.
    • (2012) Seminars in Nephrology , vol.32 , Issue.5 , pp. 437-444
    • Doria, A.1    Niewczas, M.A.2    Fiorina, P.3
  • 131
    • 36248953302 scopus 로고    scopus 로고
    • Effect of TNFalpha inhibition on urinary albumin excretion in experimental diabetic rats
    • Y. Moriwaki, T. Inokuchi, A. Yamamoto et al. , "Effect of TNFalpha inhibition on urinary albumin excretion in experimental diabetic rats, " Acta Diabetologica, vol. 44, no. 4, pp. 215-218, 2007.
    • (2007) Acta Diabetologica , vol.44 , Issue.4 , pp. 215-218
    • Moriwaki, Y.1    Inokuchi, T.2    Yamamoto, A.3
  • 132
    • 84901704299 scopus 로고    scopus 로고
    • Role of the TNF pathway in the progression of diabetic nephropathy in KK-Ay mice
    • K. Omote, T. Gohda, M. Murakoshi et al. , "Role of the TNF pathway in the progression of diabetic nephropathy in KK-Ay mice, " The American Journal of Physiology-Renal Physiology, vol. 306, no. 11, pp. F1335-F1347, 2014.
    • (2014) The American Journal of Physiology-Renal Physiology , vol.306 , Issue.11 , pp. F1335-F1347
    • Omote, K.1    Gohda, T.2    Murakoshi, M.3
  • 134
    • 22944439404 scopus 로고    scopus 로고
    • Tranilast prevents the progression of experimental diabetic nephropathy through suppression of enhanced extracellular matrix gene expression
    • H. Akahori, T. Ota, M. Torita, H. Ando, S. Kaneko, and T. Takamura, "Tranilast prevents the progression of experimental diabetic nephropathy through suppression of enhanced extracellular matrix gene expression, " Journal of Pharmacology and Experimental Therapeutics, vol. 314, no. 2, pp. 514-521, 2005.
    • (2005) Journal of Pharmacology and Experimental Therapeutics , vol.314 , Issue.2 , pp. 514-521
    • Akahori, H.1    Ota, T.2    Torita, M.3    Ando, H.4    Kaneko, S.5    Takamura, T.6
  • 135
    • 33749618332 scopus 로고    scopus 로고
    • Effect of tranilast in early-stage diabetic nephropathy
    • J. Soma, K. Sato, H. Saito, and Y. Tsuchiya, "Effect of tranilast in early-stage diabetic nephropathy, " Nephrology Dialysis Transplantation, vol. 21, no. 10, pp. 2795-2799, 2006.
    • (2006) Nephrology Dialysis Transplantation , vol.21 , Issue.10 , pp. 2795-2799
    • Soma, J.1    Sato, K.2    Saito, H.3    Tsuchiya, Y.4
  • 136
    • 55249107980 scopus 로고    scopus 로고
    • Different roles for TGF-beta and VEGF in the pathogenesis of the cardinal features of diabetic nephropathy
    • F. N. Ziyadeh, "Different roles for TGF-beta and VEGF in the pathogenesis of the cardinal features of diabetic nephropathy, " Diabetes Research and Clinical Practice, vol. 82, supplement 1, pp. S38-S41, 2008.
    • (2008) Diabetes Research and Clinical Practice , vol.82 , pp. S38-S41
    • Ziyadeh, F.N.1
  • 137
    • 79956011495 scopus 로고    scopus 로고
    • A phase 1, single-dose study of fresolimumab, an anti-TGF-antibody, in treatment-resistant primary focal segmental glomerulosclerosis
    • H. Trachtman, F. C. Fervenza, D. S. Gipson et al. , "A phase 1, single-dose study of fresolimumab, an anti-TGF-antibody, in treatment-resistant primary focal segmental glomerulosclerosis, " Kidney International, vol. 79, no. 11, pp. 1236-1243, 2011.
    • (2011) Kidney International , vol.79 , Issue.11 , pp. 1236-1243
    • Trachtman, H.1    Fervenza, F.C.2    Gipson, D.S.3
  • 138
    • 3042795227 scopus 로고    scopus 로고
    • Effect of antisense TGF-1 oligodeoxynucleotides in streptozotocin-induced diabetic rat kidney
    • H. S. Jeong, K. K. Park, S. P. Kim, I. J. Choi, I. K. Lee, and H. C. Kim, "Effect of antisense TGF-1 oligodeoxynucleotides in streptozotocin-induced diabetic rat kidney, " Journal of Korean Medical Science, vol. 19, no. 3, pp. 374-383, 2004.
    • (2004) Journal of Korean Medical Science , vol.19 , Issue.3 , pp. 374-383
    • Jeong, H.S.1    Park, K.K.2    Kim, S.P.3    Choi, I.J.4    Lee, I.K.5    Kim, H.C.6
  • 139
    • 33847011714 scopus 로고    scopus 로고
    • Evidence for a role of transforming growth factor (TGF)-beta1 in the induction of postglomerular albuminuria in diabetic nephropathy: Amelioration by soluble TGF-beta type II receptor
    • L. M. Russo, E. del Re, D. Brown, and H. Y. Lin, "Evidence for a role of transforming growth factor (TGF)-beta1 in the induction of postglomerular albuminuria in diabetic nephropathy: amelioration by soluble TGF-beta type II receptor, " Diabetes, vol. 56, no. 2, pp. 380-388, 2007.
    • (2007) Diabetes , vol.56 , Issue.2 , pp. 380-388
    • Russo, L.M.1    Del Re, E.2    Brown, D.3    Lin, H.Y.4
  • 140
    • 84872272401 scopus 로고    scopus 로고
    • Renal antifibrotic effect of n-acetyl-seryl-aspartyl-lysyl-proline in diabetic rats
    • G. Castoldi, C. R. T. di Gioia, C. Bombardi et al. , "Renal antifibrotic effect of n-acetyl-seryl-aspartyl-lysyl-proline in diabetic rats, "The American Journal of Nephrology, vol. 37, no. 1, pp. 64-73, 2013.
    • (2013) The American Journal of Nephrology , vol.37 , Issue.1 , pp. 64-73
    • Castoldi, G.1    Di Gioia, C.R.T.2    Bombardi, C.3
  • 141
    • 77955743198 scopus 로고    scopus 로고
    • Phase 1 study of anti-CTGF monoclonal antibody in patients with diabetes and microalbuminuria
    • S. G. Adler, S. Schwartz, M. E. Williams et al. , "Phase 1 study of anti-CTGF monoclonal antibody in patients with diabetes and microalbuminuria, " Clinical Journal of the American Society of Nephrology, vol. 5, no. 8, pp. 1420-1428, 2010.
    • (2010) Clinical Journal of the American Society of Nephrology , vol.5 , Issue.8 , pp. 1420-1428
    • Adler, S.G.1    Schwartz, S.2    Williams, M.E.3
  • 142
  • 143
    • 84869239084 scopus 로고    scopus 로고
    • A novel C-C chemokine receptor 2 antagonist prevents progression of albuminuria and atherosclerosis in mouse models
    • M. Okamoto, M. Fuchigami, T. Suzuki, and N. Watanabe, "A novel C-C chemokine receptor 2 antagonist prevents progression of albuminuria and atherosclerosis in mouse models, " Biological and Pharmaceutical Bulletin, vol. 35, no. 11, pp. 2069-2074, 2012.
    • (2012) Biological and Pharmaceutical Bulletin , vol.35 , Issue.11 , pp. 2069-2074
    • Okamoto, M.1    Fuchigami, M.2    Suzuki, T.3    Watanabe, N.4
  • 144
    • 84884317840 scopus 로고    scopus 로고
    • Blockade of CCL2/CCR2 signalling ameliorates diabetic nephropathy in db/db mice
    • S. J. Seok, E. S. Lee, G. T. Kim et al. , "Blockade of CCL2/CCR2 signalling ameliorates diabetic nephropathy in db/db mice, " Nephrology Dialysis Transplantation, vol. 28, no. 7, pp. 1700-1710, 2013.
    • (2013) Nephrology Dialysis Transplantation , vol.28 , Issue.7 , pp. 1700-1710
    • Seok, S.J.1    Lee, E.S.2    Kim, G.T.3
  • 145
    • 84887006703 scopus 로고    scopus 로고
    • CCR2 antagonist CCX140-B provides renal and glycemic benefits in diabetic transgenic human CCR2 knockin mice
    • T. Sullivan, Z. Miao, D. J. Dairaghi et al. , "CCR2 antagonist CCX140-B provides renal and glycemic benefits in diabetic transgenic human CCR2 knockin mice, " The American Journal of Physiology-Renal Physiology, vol. 305, no. 9, pp. F1288-F1297, 2013.
    • (2013) The American Journal of Physiology-Renal Physiology , vol.305 , Issue.9 , pp. F1288-F1297
    • Sullivan, T.1    Miao, Z.2    Dairaghi, D.J.3
  • 146
    • 84861850705 scopus 로고    scopus 로고
    • Matrix metalloproteinases in kidney homeostasis and diseases
    • R. J. Tan andY. Liu, "Matrix metalloproteinases in kidney homeostasis and diseases, " The American Journal of Physiology-Renal Physiology, vol. 302, no. 11, pp. F1351-F1361, 2012.
    • (2012) The American Journal of Physiology-Renal Physiology , vol.302 , Issue.11 , pp. F1351-F1361
    • Tan, R.J.1    Liu, Y.2
  • 147
    • 77955928306 scopus 로고    scopus 로고
    • Evaluation of role of doxycycline (amatrix metalloproteinase inhibitor) on renal functions in patients of diabetic nephropathy
    • H. K. Aggarwal, D. Jain, P. Talapatra, R. K. Yadav, T. Gupta, and K. L. Kathuria, "Evaluation of role of doxycycline (amatrix metalloproteinase inhibitor) on renal functions in patients of diabetic nephropathy, " Renal Failure, vol. 32, no. 8, pp. 941-946, 2010.
    • (2010) Renal Failure , vol.32 , Issue.8 , pp. 941-946
    • Aggarwal, H.K.1    Jain, D.2    Talapatra, P.3    Yadav, R.K.4    Gupta, T.5    Kathuria, K.L.6
  • 148
    • 79954516523 scopus 로고    scopus 로고
    • Evaluation of metalloprotease inhibitors on hypertension and diabetic nephropathy
    • J. M. Williams, J. Zhang, P. North et al. , "Evaluation of metalloprotease inhibitors on hypertension and diabetic nephropathy, " The American Journal of Physiology-Renal Physiology, vol. 300, no. 4, pp. F983-F998, 2011.
    • (2011) The American Journal of Physiology-Renal Physiology , vol.300 , Issue.4 , pp. F983-F998
    • Williams, J.M.1    Zhang, J.2    North, P.3
  • 149
    • 84924908396 scopus 로고    scopus 로고
    • MicroRNAs in kidney physiology and disease
    • P. Trionfini, A. Benigni, and G. Remuzzi, "MicroRNAs in kidney physiology and disease, " Nature Reviews Nephrology, vol. 11, no. 1, pp. 23-33, 2014.
    • (2014) Nature Reviews Nephrology , vol.11 , Issue.1 , pp. 23-33
    • Trionfini, P.1    Benigni, A.2    Remuzzi, G.3
  • 150
    • 84924922747 scopus 로고    scopus 로고
    • The role of microRNAs in diabetic nephropathy
    • H. Wu, L. Kong, S. Zhou et al. , "The role of microRNAs in diabetic nephropathy, " Journal of Diabetes Research, vol. 2014, Article ID 920134, 12 pages, 2014.
    • (2014) Journal of Diabetes Research , vol.2014
    • Wu, H.1    Kong, L.2    Zhou, S.3
  • 152
    • 84865647121 scopus 로고    scopus 로고
    • The diverse ligand repertoire of the receptor for advanced glycation endproducts and pathways to the complications of diabetes
    • R. Ramasamy, S. F. Yan, and A. M. Schmidt, "The diverse ligand repertoire of the receptor for advanced glycation endproducts and pathways to the complications of diabetes, " Vascular Pharmacology, vol. 57, no. 5-6, pp. 160-167, 2012.
    • (2012) Vascular Pharmacology , vol.57 , Issue.5-6 , pp. 160-167
    • Ramasamy, R.1    Yan, S.F.2    Schmidt, A.M.3
  • 153
    • 84920053904 scopus 로고    scopus 로고
    • Extracellular matrix is modulated in advanced glycation end products milieu via a RAGE receptor dependent pathway boosted by transforming growth factor-1 RAGE-1
    • A. I. Serban, L. Stanca, O. I. Geicu, M. C. Munteanu, M. Costache, and A. Dinischiotu, "Extracellular matrix is modulated in advanced glycation end products milieu via a RAGE receptor dependent pathway boosted by transforming growth factor-1 RAGE-1, " Journal of Diabetes, vol. 7, no. 1, pp. 114-124, 2015.
    • (2015) Journal of Diabetes , vol.7 , Issue.1 , pp. 114-124
    • Serban, A.I.1    Stanca, L.2    Geicu, O.I.3    Munteanu, M.C.4    Costache, M.5    Dinischiotu, A.6
  • 154
    • 0347360360 scopus 로고    scopus 로고
    • Long-term renal effects of a neutralizing RAGE antibody in obese type 2 diabetic mice
    • A. Flyvbjerg, L. Denner, B. F. Schrijvers et al. , "Long-term renal effects of a neutralizing RAGE antibody in obese type 2 diabetic mice, " Diabetes, vol. 53, no. 1, pp. 166-172, 2004.
    • (2004) Diabetes , vol.53 , Issue.1 , pp. 166-172
    • Flyvbjerg, A.1    Denner, L.2    Schrijvers, B.F.3
  • 155
    • 81455128723 scopus 로고    scopus 로고
    • Oral administration of ethyl acetate-soluble portion of Terminalia chebula conferring protection from streptozotocininduced diabetic mellitus and its complications
    • J. H. Kim, C. O. Hong, Y. C. Koo, S. J. Kim, and K. W. Lee, "Oral administration of ethyl acetate-soluble portion of Terminalia chebula conferring protection from streptozotocininduced diabetic mellitus and its complications, " Biological and Pharmaceutical Bulletin, vol. 34, no. 11, pp. 1702-1709, 2011.
    • (2011) Biological and Pharmaceutical Bulletin , vol.34 , Issue.11 , pp. 1702-1709
    • Kim, J.H.1    Hong, C.O.2    Koo, Y.C.3    Kim, S.J.4    Lee, K.W.5
  • 156
    • 10744223527 scopus 로고    scopus 로고
    • Randomized trial of an inhibitor of formation of advanced glycation end products in diabetic nephropathy
    • W. K. Bolton, D. C. Cattran, M. E. Williams et al. , "Randomized trial of an inhibitor of formation of advanced glycation end products in diabetic nephropathy, " American Journal of Nephrology, vol. 24, no. 1, pp. 32-40, 2004.
    • (2004) American Journal of Nephrology , vol.24 , Issue.1 , pp. 32-40
    • Bolton, W.K.1    Cattran, D.C.2    Williams, M.E.3
  • 157
    • 35548975242 scopus 로고    scopus 로고
    • Effects of pyridoxamine in combined phase 2 studies of patients with type 1 and type 2 diabetes and overt nephropathy
    • M. E. Williams, W. K. Bolton, R. G. Khalifah, T. P. Degenhardt, R. J. Schotzinger, and J. B. McGill, "Effects of pyridoxamine in combined phase 2 studies of patients with type 1 and type 2 diabetes and overt nephropathy, " American Journal of Nephrology, vol. 27, no. 6, pp. 605-614, 2007.
    • (2007) American Journal of Nephrology , vol.27 , Issue.6 , pp. 605-614
    • Williams, M.E.1    Bolton, W.K.2    Khalifah, R.G.3    Degenhardt, T.P.4    Schotzinger, R.J.5    McGill, J.B.6
  • 160
    • 3142617382 scopus 로고    scopus 로고
    • Protective effect of an oral adsorbent on renal function in chronic renal failure: Determinants of its efficacy in diabetic nephropathy
    • T. Sanaka, T. Akizawa, K. Koide, and S. Koshikawa, "Protective effect of an oral adsorbent on renal function in chronic renal failure: determinants of its efficacy in diabetic nephropathy, " Therapeutic Apheresis and Dialysis, vol. 8, no. 3, pp. 232-240, 2004.
    • (2004) Therapeutic Apheresis and Dialysis , vol.8 , Issue.3 , pp. 232-240
    • Sanaka, T.1    Akizawa, T.2    Koide, K.3    Koshikawa, S.4
  • 161
    • 48949090236 scopus 로고    scopus 로고
    • AST-120 (Kremezin) initiated in early stage chronic kidney disease stunts the progression of renal dysfunction in type 2 diabetic subjects
    • K. Konishi, S. Nakano, S.-I. Tsuda, A. Nakagawa, T. Kigoshi, and D. Koya, "AST-120 (Kremezin) initiated in early stage chronic kidney disease stunts the progression of renal dysfunction in type 2 diabetic subjects, "Diabetes Research and Clinical Practice, vol. 81, no. 3, pp. 310-315, 2008.
    • (2008) Diabetes Research and Clinical Practice , vol.81 , Issue.3 , pp. 310-315
    • Konishi, K.1    Nakano, S.2    Tsuda, S.-I.3    Nakagawa, A.4    Kigoshi, T.5    Koya, D.6
  • 164
    • 80755168875 scopus 로고    scopus 로고
    • Potential role of regulatory T cells in reversing obesity-linked insulin resistance and diabetic nephropathy
    • K. Eller, A. Kirsch, A. M. Wolf et al. , "Potential role of regulatory T cells in reversing obesity-linked insulin resistance and diabetic nephropathy, " Diabetes, vol. 60, no. 11, pp. 2954-2962, 2011.
    • (2011) Diabetes , vol.60 , Issue.11 , pp. 2954-2962
    • Eller, K.1    Kirsch, A.2    Wolf, A.M.3
  • 165
    • 79751527661 scopus 로고    scopus 로고
    • Transfused macrophages ameliorate pancreatic and renal injury in murine diabetes mellitus
    • D. Zheng, Y. Wang, Q. Cao et al. , "Transfused macrophages ameliorate pancreatic and renal injury in murine diabetes mellitus, " Nephron-Experimental Nephrology, vol. 118, no. 4, pp. e87-e99, 2011.
    • (2011) Nephron-Experimental Nephrology , vol.118 , Issue.4 , pp. e87-e99
    • Zheng, D.1    Wang, Y.2    Cao, Q.3
  • 167
    • 77951497845 scopus 로고    scopus 로고
    • Effect of the urotensin receptor antagonist palosuran in hypertensive patients with type 2 diabetic nephropathy
    • L. Vogt, C. Chiurchiu, H. Chadha-Boreham et al. , "Effect of the urotensin receptor antagonist palosuran in hypertensive patients with type 2 diabetic nephropathy, " Hypertension, vol. 55, no. 5, pp. 1206-1209, 2010.
    • (2010) Hypertension , vol.55 , Issue.5 , pp. 1206-1209
    • Vogt, L.1    Chiurchiu, C.2    Chadha-Boreham, H.3
  • 168
    • 84872785696 scopus 로고    scopus 로고
    • Sulodexide decreases albuminuria and regulates matrix protein accumulation in C57BL/6 mice with streptozotocininduced type i diabetic nephropathy
    • S. Yung, M. K. M. Chau, Q. Zhang, C. Z. Zhang, and T. M. Chan, "Sulodexide decreases albuminuria and regulates matrix protein accumulation in C57BL/6 mice with streptozotocininduced type I diabetic nephropathy, " PLoS ONE, vol. 8, no. 1, Article ID e54501, 2013.
    • (2013) PLoS ONE , vol.8 , Issue.1
    • Yung, S.1    Chau, M.K.M.2    Zhang, Q.3    Zhang, C.Z.4    Chan, T.M.5
  • 169
    • 80055018022 scopus 로고    scopus 로고
    • Sulodexide for kidney protection in type 2 diabetes patients with microalbuminuria: A randomized controlled trial
    • E. J. Lewis, J. B. Lewis, T. Greene et al. , "Sulodexide for kidney protection in type 2 diabetes patients with microalbuminuria: a randomized controlled trial, " American Journal of Kidney Diseases, vol. 58, no. 5, pp. 729-736, 2011.
    • (2011) American Journal of Kidney Diseases , vol.58 , Issue.5 , pp. 729-736
    • Lewis, E.J.1    Lewis, J.B.2    Greene, T.3
  • 170
    • 84863393468 scopus 로고    scopus 로고
    • Sulodexide fails to demonstrate renoprotection in overt type 2 diabetic nephropathy
    • D. K. Packham, R. Wolfe, A. T. Reutens et al. , "Sulodexide fails to demonstrate renoprotection in overt type 2 diabetic nephropathy, " Journal of theAmericanSociety ofNephrology, vol. 23, no. 1, pp. 123-130, 2012.
    • (2012) Journal of TheAmericanSociety OfNephrology , vol.23 , Issue.1 , pp. 123-130
    • Packham, D.K.1    Wolfe, R.2    Reutens, A.T.3


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