Blockade of CCL2/CCR2 signalling ameliorates diabetic nephropathy in db/db mice

Nephrology Dialysis Transplantation

Volumn 28, Issue 7, 2013, Pages 1700-1710

  Seok, Su Jin ^a   Lee, Eun Soo ^b   Kim, Geun Tae ^a   Hyun, Miri ^a   Lee, Ji Hye ^a   Chen, Sheldon ^c   Choi, Ran ^b   Kim, Hong Min ^b   Lee, Eun Young ^a   Chung, Choon Hee ^b  

^a Soonchunhyang University College of Medicine   (South Korea)

^b Yonsei University Wonju   (South Korea)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Albuminuria; CCL2; CCR2; Diabetic nephropathy

Indexed keywords

ARGINASE; ARGINASE II; CD68 ANTIGEN; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR2 ANTAGONIST; GLUCOSE; MALONALDEHYDE; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; NEPHRIN; RS 102895; UNCLASSIFIED DRUG; VASCULOTROPIN;

ALBUMINURIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE MEASUREMENT; BODY WEIGHT; CELL EXPANSION; CELL INFILTRATION; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DISEASE CONTROL; DOWN REGULATION; DRUG EFFECT; DRUG EFFICACY; DRUG RESPONSE; GENE EXPRESSION; GLOMERULONEPHRITIS; GLOMERULUS BASEMENT MEMBRANE; GLUCOSE BLOOD LEVEL; KIDNEY MASS; KIDNEY STRUCTURE; MACROPHAGE; MALE; MESANGIUM CELL; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UPREGULATION;

ALBUMINURIA; CCL2; CCR2; DIABETIC NEPHROPATHY;

ALBUMINURIA; ANIMALS; BLOOD GLUCOSE; BLOTTING, WESTERN; CHEMOKINE CCL2; CYTOKINES; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; FLOW CYTOMETRY; GLUCOSE TOLERANCE TEST; INSULIN RESISTANCE; MALE; MICE; MICE, INBRED C57BL; OXIDATIVE STRESS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, CCR2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84884317840     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfs555     Document Type: Article

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