-
1
-
-
0002366905
-
Selective estrogen receptor modulators (SERMs): a first step in the development of perfect hormone replacement therapy regimen
-
McDonnell D.P. Selective estrogen receptor modulators (SERMs): a first step in the development of perfect hormone replacement therapy regimen. J. Soc. Gynecol. Investig. 2000, 7:S10-S15.
-
(2000)
J. Soc. Gynecol. Investig.
, vol.7
-
-
McDonnell, D.P.1
-
2
-
-
4344632533
-
The molecular determinants of estrogen receptor pharmacology
-
McDonnell D.P. The molecular determinants of estrogen receptor pharmacology. Maturitas 2004, 48(Suppl. 1):S7-12.
-
(2004)
Maturitas
, vol.48
, Issue.SUPPL. 1
-
-
McDonnell, D.P.1
-
3
-
-
34948820661
-
27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen
-
Umetani M., et al. 27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen. Nat. Med. 2007, 13:1185-1192.
-
(2007)
Nat. Med.
, vol.13
, pp. 1185-1192
-
-
Umetani, M.1
-
4
-
-
66349134159
-
Fifty years of advances in bile acid synthesis and metabolism
-
Russell D.W. Fifty years of advances in bile acid synthesis and metabolism. J. Lipid. Res. 2009, 50(Suppl.):S120-S125.
-
(2009)
J. Lipid. Res.
, vol.50
, Issue.SUPPL.
-
-
Russell, D.W.1
-
5
-
-
67349262029
-
Interactions of oxysterols with membranes and proteins
-
Olkkonen V.M., Hynynen R. Interactions of oxysterols with membranes and proteins. Mol. Aspects Med. 2009, 30:123-133.
-
(2009)
Mol. Aspects Med.
, vol.30
, pp. 123-133
-
-
Olkkonen, V.M.1
Hynynen, R.2
-
6
-
-
0029805887
-
An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
-
Janowski B.A., et al. An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha. Nature 1996, 383:728-731.
-
(1996)
Nature
, vol.383
, pp. 728-731
-
-
Janowski, B.A.1
-
7
-
-
66349136255
-
Are side-chain oxidized oxysterols regulators also in vivo?
-
Björkhem I. Are side-chain oxidized oxysterols regulators also in vivo?. J. Lipid Res. 2009, 50(Suppl):S213-S218.
-
(2009)
J. Lipid Res.
, vol.50
, Issue.SUPPL.
-
-
Björkhem, I.1
-
8
-
-
0034595445
-
Disruption of the oxysterol 7alpha-hydroxylase gene in mice
-
Li-Hawkins J., et al. Disruption of the oxysterol 7alpha-hydroxylase gene in mice. J. Biol. Chem. 2000, 275:16536-16542.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 16536-16542
-
-
Li-Hawkins, J.1
-
9
-
-
0034672672
-
Oxysterol biosynthetic enzymes
-
Russell D.W. Oxysterol biosynthetic enzymes. Biochim. Biophys. Acta 2000, 1529:126-135.
-
(2000)
Biochim. Biophys. Acta
, vol.1529
, pp. 126-135
-
-
Russell, D.W.1
-
10
-
-
0032890337
-
Oxysterols and atherosclerosis
-
Brown A.J., Jessup W. Oxysterols and atherosclerosis. Atherosclerosis 1999, 142:1-28.
-
(1999)
Atherosclerosis
, vol.142
, pp. 1-28
-
-
Brown, A.J.1
Jessup, W.2
-
11
-
-
77952304021
-
Cerebrotendinous xanthomatosis: an inborn error in bile acid synthesis with defined mutations but still a challenge
-
Björkhem I., Hansson M. Cerebrotendinous xanthomatosis: an inborn error in bile acid synthesis with defined mutations but still a challenge. Biochem. Biophys. Res. Commun. 2010, 396:46-49.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.396
, pp. 46-49
-
-
Björkhem, I.1
Hansson, M.2
-
12
-
-
77950599782
-
Marked accumulation of 27-hydroxycholesterol in SPG5 patients with hereditary spastic paresis
-
Schule R., et al. Marked accumulation of 27-hydroxycholesterol in SPG5 patients with hereditary spastic paresis. J. Lipid Res. 2010, 51:819-823.
-
(2010)
J. Lipid Res.
, vol.51
, pp. 819-823
-
-
Schule, R.1
-
13
-
-
59149088091
-
Serum concentration of 27-hydroxycholesterol predicts the effects of high-cholesterol diet on plasma LDL cholesterol level
-
Hirayama T., et al. Serum concentration of 27-hydroxycholesterol predicts the effects of high-cholesterol diet on plasma LDL cholesterol level. Hepatol. Res. 2009, 39:149-156.
-
(2009)
Hepatol. Res.
, vol.39
, pp. 149-156
-
-
Hirayama, T.1
-
14
-
-
40949116379
-
Measurement of F2-isoprostanes, hydroxyeicosatetraenoic products, and oxysterols from a single plasma sample
-
Lee C.Y., et al. Measurement of F2-isoprostanes, hydroxyeicosatetraenoic products, and oxysterols from a single plasma sample. Free Radic. Biol. Med. 2008, 44:1314-1322.
-
(2008)
Free Radic. Biol. Med.
, vol.44
, pp. 1314-1322
-
-
Lee, C.Y.1
-
15
-
-
0033386688
-
Structure and functions of human oxysterol 7alpha-hydroxylase cDNAs and gene CYP7B1
-
Wu Z., et al. Structure and functions of human oxysterol 7alpha-hydroxylase cDNAs and gene CYP7B1. J. Lipid Res. 1999, 40:2195-2203.
-
(1999)
J. Lipid Res.
, vol.40
, pp. 2195-2203
-
-
Wu, Z.1
-
16
-
-
70350417597
-
CYP7B1: one cytochrome P450, two human genetic diseases, and multiple physiological functions
-
Stiles A.R., et al. CYP7B1: one cytochrome P450, two human genetic diseases, and multiple physiological functions. J. Biol. Chem. 2009, 284:28485-28489.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 28485-28489
-
-
Stiles, A.R.1
-
17
-
-
14544305043
-
Early onset of puberty and early ovarian failure in CYP7B1 knockout mice
-
Omoto Y., et al. Early onset of puberty and early ovarian failure in CYP7B1 knockout mice. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:2814-2819.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 2814-2819
-
-
Omoto, Y.1
-
18
-
-
38049008502
-
27-Hydroxycholesterol is an endogenous selective estrogen receptor modulator
-
DuSell C.D., et al. 27-Hydroxycholesterol is an endogenous selective estrogen receptor modulator. Mol. Endocrinol. 2008, 22:65-77.
-
(2008)
Mol. Endocrinol.
, vol.22
, pp. 65-77
-
-
DuSell, C.D.1
-
19
-
-
34648837875
-
Lipoprotein distribution and biological variation of 24S- and 27-hydroxycholesterol in healthy volunteers
-
Burkard I., et al. Lipoprotein distribution and biological variation of 24S- and 27-hydroxycholesterol in healthy volunteers. Atherosclerosis 2007, 194:71-78.
-
(2007)
Atherosclerosis
, vol.194
, pp. 71-78
-
-
Burkard, I.1
-
20
-
-
0032769064
-
27-Hydroxycholesterol: production rates in normal human subjects
-
Duane W.C., Javitt N.B. 27-Hydroxycholesterol: production rates in normal human subjects. J. Lipid Res. 1999, 40:1194-1199.
-
(1999)
J. Lipid Res.
, vol.40
, pp. 1194-1199
-
-
Duane, W.C.1
Javitt, N.B.2
-
21
-
-
0031576814
-
Localization of sterol 27-hydroxylase immuno-reactivity in human atherosclerotic plaques
-
Crisby M., et al. Localization of sterol 27-hydroxylase immuno-reactivity in human atherosclerotic plaques. Biochim. Biophys. Acta 1997, 1344:278-285.
-
(1997)
Biochim. Biophys. Acta
, vol.1344
, pp. 278-285
-
-
Crisby, M.1
-
22
-
-
0036172426
-
Disease stage-dependent accumulation of lipid and protein oxidation products in human atherosclerosis
-
Upston J.M., et al. Disease stage-dependent accumulation of lipid and protein oxidation products in human atherosclerosis. Am. J. Pathol. 2002, 160:701-710.
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 701-710
-
-
Upston, J.M.1
-
23
-
-
33745187361
-
Estrogen receptor alpha mediates 17alpha-ethynylestradiol causing hepatotoxicity
-
Yamamoto Y., et al. Estrogen receptor alpha mediates 17alpha-ethynylestradiol causing hepatotoxicity. J. Biol. Chem. 2006, 281:16625-16631.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 16625-16631
-
-
Yamamoto, Y.1
-
24
-
-
33644638521
-
Estrogen receptors and human disease
-
Deroo B.J., Korach K.S. Estrogen receptors and human disease. J. Clin. Invest. 2006, 116:561-570.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 561-570
-
-
Deroo, B.J.1
Korach, K.S.2
-
25
-
-
0033542402
-
The protective effects of estrogen on the cardiovascular system
-
Mendelsohn M.E., Karas R.H. The protective effects of estrogen on the cardiovascular system. N. Engl. J. Med. 1999, 340:1801-1811.
-
(1999)
N. Engl. J. Med.
, vol.340
, pp. 1801-1811
-
-
Mendelsohn, M.E.1
Karas, R.H.2
-
26
-
-
0035936528
-
Estradiol accelerates reendothelialization in mouse carotid artery through estrogen receptor-alpha but not estrogen receptor-beta
-
Brouchet L., et al. Estradiol accelerates reendothelialization in mouse carotid artery through estrogen receptor-alpha but not estrogen receptor-beta. Circulation 2001, 103:423-428.
-
(2001)
Circulation
, vol.103
, pp. 423-428
-
-
Brouchet, L.1
-
27
-
-
0037205290
-
Estrogen receptor-alpha mediates the protective effects of estrogen against vascular injury
-
Pare G., et al. Estrogen receptor-alpha mediates the protective effects of estrogen against vascular injury. Circ. Res. 2002, 90:1087-1092.
-
(2002)
Circ. Res.
, vol.90
, pp. 1087-1092
-
-
Pare, G.1
-
28
-
-
77955006975
-
Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice
-
Chambliss K.L., et al. Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice. J. Clin. Invest. 2010, 120:2319-2330.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 2319-2330
-
-
Chambliss, K.L.1
-
29
-
-
0037127027
-
Abnormal vascular function and hypertension in mice deficient in estrogen receptor beta
-
Zhu Y., et al. Abnormal vascular function and hypertension in mice deficient in estrogen receptor beta. Science 2002, 295:505-508.
-
(2002)
Science
, vol.295
, pp. 505-508
-
-
Zhu, Y.1
-
30
-
-
0036892157
-
Minireview: estrogen and mouse models of atherosclerosis
-
Hodgin J.B., Maeda N. Minireview: estrogen and mouse models of atherosclerosis. Endocrinology 2002, 143:4495-4501.
-
(2002)
Endocrinology
, vol.143
, pp. 4495-4501
-
-
Hodgin, J.B.1
Maeda, N.2
-
31
-
-
20444398494
-
Molecular and cellular basis of cardiovascular gender differences
-
Mendelsohn M.E., Karas R.H. Molecular and cellular basis of cardiovascular gender differences. Science 2005, 308:1583-1587.
-
(2005)
Science
, vol.308
, pp. 1583-1587
-
-
Mendelsohn, M.E.1
Karas, R.H.2
-
32
-
-
0023099735
-
Menopause and the risk of coronary heart disease in women
-
Colditz G.A., et al. Menopause and the risk of coronary heart disease in women. N. Engl. J. Med. 1987, 316:1105-1110.
-
(1987)
N. Engl. J. Med.
, vol.316
, pp. 1105-1110
-
-
Colditz, G.A.1
-
33
-
-
3042852097
-
Current controversies regarding the cardiovascular effects of hormone therapy
-
Karas R.H. Current controversies regarding the cardiovascular effects of hormone therapy. Clin. Obstet. Gynecol. 2004, 47:489-499.
-
(2004)
Clin. Obstet. Gynecol.
, vol.47
, pp. 489-499
-
-
Karas, R.H.1
-
34
-
-
2542540731
-
Hormone therapy: physiological complexity belies therapeutic simplicity
-
Turgeon J.L., et al. Hormone therapy: physiological complexity belies therapeutic simplicity. Science 2000, 304:1269-1273.
-
(2000)
Science
, vol.304
, pp. 1269-1273
-
-
Turgeon, J.L.1
-
35
-
-
0032547326
-
Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group
-
Hulley S., et al. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. JAMA 1998, 280:605-613.
-
(1998)
JAMA
, vol.280
, pp. 605-613
-
-
Hulley, S.1
-
36
-
-
0037125379
-
Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial
-
Rossouw J.E., et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. JAMA 2002, 288:321-333.
-
(2002)
JAMA
, vol.288
, pp. 321-333
-
-
Rossouw, J.E.1
-
37
-
-
77955868505
-
Postmenopausal hormone therapy: an Endocrine Society scientific statement
-
Santen R., et al. Postmenopausal hormone therapy: an Endocrine Society scientific statement. J. Clin. Endocrinol. Metab. 2010, 95(Suppl. 1):s1-s66.
-
(2010)
J. Clin. Endocrinol. Metab.
, vol.95
, Issue.SUPPL. 1
-
-
Santen, R.1
-
38
-
-
0037434599
-
Understanding the divergent data on postmenopausal hormone therapy
-
Grodstein F., et al. Understanding the divergent data on postmenopausal hormone therapy. N. Engl. J Med. 2003, 348:645-650.
-
(2003)
N. Engl. J Med.
, vol.348
, pp. 645-650
-
-
Grodstein, F.1
-
39
-
-
0033599278
-
Prevalence and extent of atherosclerosis in adolescents and young adults: implications for prevention from the Pathobiological Determinants of Atherosclerosis in Youth Study
-
Strong J.P., et al. Prevalence and extent of atherosclerosis in adolescents and young adults: implications for prevention from the Pathobiological Determinants of Atherosclerosis in Youth Study. JAMA 1999, 281:727-735.
-
(1999)
JAMA
, vol.281
, pp. 727-735
-
-
Strong, J.P.1
-
40
-
-
0014282153
-
Distribution of coronary and aortic atherosclerosis by geographic location, race, and sex
-
Tejada C., et al. Distribution of coronary and aortic atherosclerosis by geographic location, race, and sex. Lab. Invest. 1968, 18:509-526.
-
(1968)
Lab. Invest.
, vol.18
, pp. 509-526
-
-
Tejada, C.1
-
41
-
-
18844393948
-
Controversies about HRT - lessons from monkey models
-
Clarkson T.B., Appt S.E. Controversies about HRT - lessons from monkey models. Maturitas 2005, 51:64-74.
-
(2005)
Maturitas
, vol.51
, pp. 64-74
-
-
Clarkson, T.B.1
Appt, S.E.2
-
42
-
-
85007758538
-
ABC of breast diseases. Breast cancer - epidemiology, risk factors, and genetics
-
McPherson K., et al. ABC of breast diseases. Breast cancer - epidemiology, risk factors, and genetics. BMJ 2000, 321:624-628.
-
(2000)
BMJ
, vol.321
, pp. 624-628
-
-
McPherson, K.1
-
43
-
-
34748827491
-
Optimizing the antihormonal treatment and prevention of breast cancer
-
Patel R.R., et al. Optimizing the antihormonal treatment and prevention of breast cancer. Breast Cancer 2007, 14:113-122.
-
(2007)
Breast Cancer
, vol.14
, pp. 113-122
-
-
Patel, R.R.1
-
44
-
-
33751009646
-
What do we know about the mechanisms of aromatase inhibitor resistance?
-
Chen S., et al. What do we know about the mechanisms of aromatase inhibitor resistance?. J. Steroid. Biochem. Mol. Biol. 2006, 102:232-240.
-
(2006)
J. Steroid. Biochem. Mol. Biol.
, vol.102
, pp. 232-240
-
-
Chen, S.1
-
46
-
-
13644268580
-
Atherogenic lipid profile and elevated lipoprotein (a) are associated with lower bone mineral density in early postmenopausal overweight women
-
Orozco P. Atherogenic lipid profile and elevated lipoprotein (a) are associated with lower bone mineral density in early postmenopausal overweight women. Eur. J. Epidemiol. 2004, 19:1105-1112.
-
(2004)
Eur. J. Epidemiol.
, vol.19
, pp. 1105-1112
-
-
Orozco, P.1
-
47
-
-
0037262545
-
Does serum cholesterol contribute to vertebral bone loss in postmenopausal women?
-
Tanko L.B., et al. Does serum cholesterol contribute to vertebral bone loss in postmenopausal women?. Bone 2003, 32:8-14.
-
(2003)
Bone
, vol.32
, pp. 8-14
-
-
Tanko, L.B.1
-
48
-
-
77954892925
-
The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis
-
DuSell C.D., et al. The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis. Endocrinology 2010, 151:3675-3685.
-
(2010)
Endocrinology
, vol.151
, pp. 3675-3685
-
-
DuSell, C.D.1
|