Amplification of oxidative stress by a dual stimuli-responsive hybrid drug enhances cancer cell death

Nature Communications

Volumn 6, Issue , 2015, Pages

  Noh, Joungyoun ^a   Kwon, Byeongsu ^a   Han, Eunji ^a   Park, Minhyung ^a   Yang, Wonseok ^a   Cho, Wooram ^a   Yoo, Wooyoung ^a   Khang, Gilson ^a   Lee, Dongwon ^a  

^a Chonbuk National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CAMPTOTHECIN; CINNAMALDEHYDE; GLUTATHIONE; HYDROGEN PEROXIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; QUINONE DERIVATIVE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; [4 (1,3,2 DIOXABORINAN 2 YL)BENZYL [(5 METHYL 2 STYRYL 1,3 DIOXAN 5 YL) METHYL] CARBONATE]; 4-(1,3,2-DIOXABORINAN-2-YL)BENZYL ((5-METHYL-2-STYRYL-1,3-DIOXAN-5-YL)METHYL)CARBONATE; BORON DERIVATIVE; ESTER;

ALDEHYDE; CANCER; CYTOLOGY; DRUG; OXIDATION; PH; SCAVENGING (CHEMISTRY);

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CHEMOLUMINESCENCE; CYTOTOXICITY; DNA FRAGMENTATION ASSAY; HUMAN; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PH; TANDEM MASS SPECTROMETRY; TUMOR XENOGRAFT; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; CHEMISTRY; DNA FRAGMENTATION; DRUG EFFECTS; MALE; NEOPLASMS, EXPERIMENTAL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUDE MOUSE; PROCEDURES; RANDOMIZATION; SYNTHESIS;

ANIMALS; ANTINEOPLASTIC AGENTS; BORON COMPOUNDS; CELL LINE; CHROMATOGRAPHY, LIQUID; DNA FRAGMENTATION; ESTERS; HYDROGEN PEROXIDE; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASMS, EXPERIMENTAL; OXIDATIVE STRESS; RANDOM ALLOCATION; REACTIVE OXYGEN SPECIES; TANDEM MASS SPECTROMETRY;

EID: 84928485228     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7907     Document Type: Article

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