The cinnamon-derived Michael acceptor cinnamic aldehyde impairs melanoma cell proliferation, invasiveness, and tumor growth

Free Radical Biology and Medicine

Volumn 46, Issue 2, 2009, Pages 220-231

  Cabello, Christopher M ^a   Bair III, Warner B ^a   Lamore, Sarah D ^a   Ley, Stephanie ^a   Bause, Alexandra S ^a   Azimian, Sara ^a   Wondrak, Georg T ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

Cinnamic aldehyde; Free radicals; Melanoma; Michael acceptor; NF B; Oxidative stress; p21 (CDKN1A); Xenograft

Indexed keywords

CINNAMALDEHYDE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; PEROXIREDOXIN; PROCASPASE 3; REACTIVE OXYGEN METABOLITE; SULFIREDOXIN 1; THIOREDOXIN REDUCTASE 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL INVASION; CELL PROLIFERATION; CELL VIABILITY; CINNAMON; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA SYNTHESIS; HUMAN; HUMAN CELL; IC 50; MELANOMA CELL; MICHAEL ADDITION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SCID MOUSE; TUMOR GROWTH;

ACROLEIN; ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; CINNAMOMUM ZEYLANICUM; CYCLIN-DEPENDENT KINASE INHIBITOR P21; G1 PHASE; GENE EXPRESSION PROFILING; HEME OXYGENASE-1; HUMANS; INTERLEUKIN-8; MELANOMA; MICE; MICE, SCID; MICROARRAY ANALYSIS; NEOPLASM INVASIVENESS; NEOPLASM TRANSPLANTATION; NF-KAPPA B; OXIDATIVE STRESS; OXIDOREDUCTASES ACTING ON SULFUR GROUP DONORS; PLANT GROWTH REGULATORS; SIGNAL TRANSDUCTION; THIOREDOXIN REDUCTASE 1; TUMOR NECROSIS FACTOR-ALPHA;

CINNAMOMUM VERUM;

EID: 58049100595     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2008.10.025     Document Type: Article

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