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Volumn 7, Issue 1, 2015, Pages

Post-mortem analysis of neuroinflammatory changes in human Alzheimer's disease

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[No Author keywords available]

Indexed keywords

CYTOKINE;

EID: 84928480969     PISSN: None     EISSN: 17589193     Source Type: Journal    
DOI: 10.1186/s13195-015-0126-1     Document Type: Article
Times cited : (110)

References (76)
  • 1
    • 78649822157 scopus 로고    scopus 로고
    • Neuropathology of epilepsy and psychosis: The contributions of J.A.N. Corsellis
    • Kasper BS, Taylor DC, Janz D, Kasper EM, Maier M, Williams MR, et al. Neuropathology of epilepsy and psychosis: the contributions of J.A.N. Corsellis. Brain. 2010;133:3795-805.
    • (2010) Brain. , vol.133 , pp. 3795-3805
    • Kasper, B.S.1    Taylor, D.C.2    Janz, D.3    Kasper, E.M.4    Maier, M.5    Williams, M.R.6
  • 2
    • 84904752371 scopus 로고    scopus 로고
    • Successful therapies for Alzheimer's disease: Why so many in animal models and none in humans?
    • Franco R, Cedazo-Minguez A. Successful therapies for Alzheimer's disease: why so many in animal models and none in humans? Front Pharmacol. 2014;5:146.
    • (2014) Front Pharmacol. , vol.5 , pp. 146
    • Franco, R.1    Cedazo-Minguez, A.2
  • 4
    • 84928493049 scopus 로고    scopus 로고
    • Brain Banks in the world [ http://wwwbrainnet-europeorg/indexphp?option=com-content&view=article&id=102&Itemid=102 ]
    • Brain Banks in the World
  • 5
    • 84872733391 scopus 로고    scopus 로고
    • Microglia of the aged brain: Primed to be activated and resistant to regulation
    • 1:CAS:528:DC%2BC3sXhsVWrs78%3D 23039106
    • Norden DM, Godbout JP. Microglia of the aged brain: primed to be activated and resistant to regulation. Neuropathol Appl Neurobiol. 2013;39:19-34.
    • (2013) Neuropathol Appl Neurobiol. , vol.39 , pp. 19-34
    • Norden, D.M.1    Godbout, J.P.2
  • 6
    • 0037998074 scopus 로고    scopus 로고
    • Biochemical and molecular studies using human autopsy brain tissue
    • 1:CAS:528:DC%2BD3sXnslyrs7g%3D 12694381
    • Hynd MR, Lewohl JM, Scott HL, Dodd PR. Biochemical and molecular studies using human autopsy brain tissue. J Neurochem. 2003;85:543-62.
    • (2003) J Neurochem. , vol.85 , pp. 543-562
    • Hynd, M.R.1    Lewohl, J.M.2    Scott, H.L.3    Dodd, P.R.4
  • 7
    • 84872699164 scopus 로고    scopus 로고
    • Systemic inflammation and Alzheimer's disease
    • 1:CAS:528:DC%2BC3sXhsVWrs74%3D 23046210
    • Holmes C. Systemic inflammation and Alzheimer's disease. Neuropathol Appl Neurobiol. 2013;39:51-68.
    • (2013) Neuropathol Appl Neurobiol. , vol.39 , pp. 51-68
    • Holmes, C.1
  • 8
    • 70349570588 scopus 로고    scopus 로고
    • Systemic inflammation and disease progression in Alzheimer disease
    • 1:STN:280:DC%2BD1MnhtFSjug%3D%3D 19738171
    • Holmes C, Cunningham C, Zotova E, Woolford J, Dean C, Kerr S, et al. Systemic inflammation and disease progression in Alzheimer disease. Neurology. 2009;73:768-74.
    • (2009) Neurology. , vol.73 , pp. 768-774
    • Holmes, C.1    Cunningham, C.2    Zotova, E.3    Woolford, J.4    Dean, C.5    Kerr, S.6
  • 10
    • 33846585119 scopus 로고    scopus 로고
    • Systemic infections and inflammation affect chronic neurodegeneration
    • 1:CAS:528:DC%2BD2sXpvVCisg%3D%3D 17220915
    • Perry VH, Cunningham C, Holmes C. Systemic infections and inflammation affect chronic neurodegeneration. Nat Rev Immunol. 2007;7:161-7.
    • (2007) Nat Rev Immunol. , vol.7 , pp. 161-167
    • Perry, V.H.1    Cunningham, C.2    Holmes, C.3
  • 11
    • 58349119112 scopus 로고    scopus 로고
    • Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease
    • 1:CAS:528:DC%2BD1MXhtFeksrc%3D 18801476
    • Cunningham C, Campion S, Lunnon K, Murray CL, Woods JF, Deacon RM, et al. Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease. Biol Psychiatry. 2009;65:304-12.
    • (2009) Biol Psychiatry. , vol.65 , pp. 304-312
    • Cunningham, C.1    Campion, S.2    Lunnon, K.3    Murray, C.L.4    Woods, J.F.5    Deacon, R.M.6
  • 12
    • 78650841769 scopus 로고    scopus 로고
    • Controls for immunocytochemistry: An update
    • 1:CAS:528:DC%2BC3MXkvVOlsLs%3D 20852036
    • Burry RW. Controls for immunocytochemistry: an update. J Histochem Cytochem. 2011;59:6-12.
    • (2011) J Histochem Cytochem. , vol.59 , pp. 6-12
    • Burry, R.W.1
  • 16
    • 80052070571 scopus 로고    scopus 로고
    • APOE and Alzheimer disease: A major gene with semi-dominant inheritance
    • 1:CAS:528:DC%2BC3MXhtVOktbvI 21556001
    • Genin E, Hannequin D, Wallon D, Sleegers K, Hiltunen M, Combarros O, et al. APOE and Alzheimer disease: a major gene with semi-dominant inheritance. Mol Psychiatry. 2011;16:903-7.
    • (2011) Mol Psychiatry. , vol.16 , pp. 903-907
    • Genin, E.1    Hannequin, D.2    Wallon, D.3    Sleegers, K.4    Hiltunen, M.5    Combarros, O.6
  • 17
    • 70349558522 scopus 로고    scopus 로고
    • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
    • 1:CAS:528:DC%2BD1MXhtV2gsbrM 19734902
    • Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet. 2009;41:1088-93.
    • (2009) Nat Genet. , vol.41 , pp. 1088-1093
    • Harold, D.1    Abraham, R.2    Hollingworth, P.3    Sims, R.4    Gerrish, A.5    Hamshere, M.L.6
  • 18
    • 78549264026 scopus 로고    scopus 로고
    • Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
    • 1:CAS:528:DC%2BD1MXhtV2gsb%2FK 19734903
    • Lambert JC, Heath S, Even G, Campion D, Sleegers K, Hiltunen M, et al. Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat Genet. 2009;41:1094-9.
    • (2009) Nat Genet. , vol.41 , pp. 1094-1099
    • Lambert, J.C.1    Heath, S.2    Even, G.3    Campion, D.4    Sleegers, K.5    Hiltunen, M.6
  • 19
    • 0031831690 scopus 로고    scopus 로고
    • Microglial activation in Alzheimer disease: Association with APOE genotype
    • 1:CAS:528:DyaK1cXksFCmsbc%3D 9669695
    • Egensperger R, Kosel S, von Eitzen U, Graeber MB. Microglial activation in Alzheimer disease: association with APOE genotype. Brain Pathol. 1998;8:439-47.
    • (1998) Brain Pathol. , vol.8 , pp. 439-447
    • Egensperger, R.1    Kosel, S.2    Von Eitzen, U.3    Graeber, M.B.4
  • 20
    • 0035283401 scopus 로고    scopus 로고
    • Apolipoprotein e modulates glial activation and the endogenous central nervous system inflammatory response
    • 1:CAS:528:DC%2BD3MXhs1Cjtb8%3D 11240021
    • Lynch JR, Morgan D, Mance J, Matthew WD, Laskowitz DT. Apolipoprotein E modulates glial activation and the endogenous central nervous system inflammatory response. J Neuroimmunol. 2001;114:107-13.
    • (2001) J Neuroimmunol. , vol.114 , pp. 107-113
    • Lynch, J.R.1    Morgan, D.2    Mance, J.3    Matthew, W.D.4    Laskowitz, D.T.5
  • 21
    • 84872706357 scopus 로고    scopus 로고
    • Activation patterns of microglia and their identification in the human brain
    • 1:STN:280:DC%2BC3s3jt1altQ%3D%3D 23252647
    • Boche D, Perry VH, Nicoll JA. Activation patterns of microglia and their identification in the human brain. Neuropathol Appl Neurobiol. 2013;39:3-18.
    • (2013) Neuropathol Appl Neurobiol. , vol.39 , pp. 3-18
    • Boche, D.1    Perry, V.H.2    Nicoll, J.A.3
  • 23
    • 84883315336 scopus 로고    scopus 로고
    • Inflammatory components in human Alzheimer's disease and after active amyloid-beta42 immunization
    • Zotova E, Bharambe V, Cheaveau M, Morgan W, Holmes C, Harris S, et al. Inflammatory components in human Alzheimer's disease and after active amyloid-beta42 immunization. Brain. 2013;136:2677-96.
    • (2013) Brain. , vol.136 , pp. 2677-2696
    • Zotova, E.1    Bharambe, V.2    Cheaveau, M.3    Morgan, W.4    Holmes, C.5    Harris, S.6
  • 24
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • 1:CAS:528:DC%2BD3sXovVw%3D 12511873
    • Gordon S. Alternative activation of macrophages. Nat Rev Immunol. 2003;3:23-35.
    • (2003) Nat Rev Immunol. , vol.3 , pp. 23-35
    • Gordon, S.1
  • 25
    • 70349807619 scopus 로고    scopus 로고
    • Immune activation in brain aging and neurodegeneration: Too much or too little?
    • 1:CAS:528:DC%2BD1MXhsFajsbbO 19840553
    • Lucin KM, Wyss-Coray T. Immune activation in brain aging and neurodegeneration: too much or too little? Neuron. 2009;64:110-22.
    • (2009) Neuron. , vol.64 , pp. 110-122
    • Lucin, K.M.1    Wyss-Coray, T.2
  • 26
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • 1:CAS:528:DC%2BD1cXhsVWlsLfI 19029990
    • Mosser DM, Edwards JP. Exploring the full spectrum of macrophage activation. Nat Rev Immunol. 2008;8:958-69.
    • (2008) Nat Rev Immunol. , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 27
    • 77949901284 scopus 로고    scopus 로고
    • Assessing activation states in microglia
    • 1:CAS:528:DC%2BC3cXlsFKnu74%3D 20205642
    • Colton C, Wilcock DM. Assessing activation states in microglia. CNS Neurol Disord Drug Targets. 2010;9:174-91.
    • (2010) CNS Neurol Disord Drug Targets. , vol.9 , pp. 174-191
    • Colton, C.1    Wilcock, D.M.2
  • 28
    • 70449526190 scopus 로고    scopus 로고
    • Heterogeneity of microglial activation in the innate immune response in the brain
    • Colton CA. Heterogeneity of microglial activation in the innate immune response in the brain. J Neuroimmune Pharmacol. 2009;4:399-418.
    • (2009) J Neuroimmune Pharmacol. , vol.4 , pp. 399-418
    • Colton, C.A.1
  • 29
    • 67650966680 scopus 로고    scopus 로고
    • Microglial physiology: Unique stimuli, specialized responses
    • 1:CAS:528:DC%2BD1MXlsFSlsbs%3D 19302036
    • Ransohoff RM, Perry VH. Microglial physiology: unique stimuli, specialized responses. Annu Rev Immunol. 2009;27:119-45.
    • (2009) Annu Rev Immunol. , vol.27 , pp. 119-145
    • Ransohoff, R.M.1    Perry, V.H.2
  • 31
    • 0027354484 scopus 로고
    • Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease
    • 1:STN:280:DyaK3s7jvVOntQ%3D%3D 8423065
    • Dickson DW, Lee SC, Mattiace LA, Yen SH, Brosnan C. Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease. Glia. 1993;7:75-83.
    • (1993) Glia. , vol.7 , pp. 75-83
    • Dickson, D.W.1    Lee, S.C.2    Mattiace, L.A.3    Yen, S.H.4    Brosnan, C.5
  • 32
    • 79960997729 scopus 로고    scopus 로고
    • Soothing the inflamed brain: Effect of non-steroidal anti-inflammatory drugs on Alzheimer's disease pathology
    • 1:CAS:528:DC%2BC3MXkslaht78%3D 21143138
    • Hoozemans JJ, Veerhuis R, Rozemuller JM, Eikelenboom P. Soothing the inflamed brain: effect of non-steroidal anti-inflammatory drugs on Alzheimer's disease pathology. CNS Neurol Disord Drug Targets. 2011;10:57-67.
    • (2011) CNS Neurol Disord Drug Targets. , vol.10 , pp. 57-67
    • Hoozemans, J.J.1    Veerhuis, R.2    Rozemuller, J.M.3    Eikelenboom, P.4
  • 33
    • 84897976299 scopus 로고    scopus 로고
    • Microglial priming in neurodegenerative disease
    • 1:CAS:528:DC%2BC2cXkvVKjurY%3D 24638131
    • Perry VH, Holmes C. Microglial priming in neurodegenerative disease. Nat Rev Neurol. 2014;10:217-24.
    • (2014) Nat Rev Neurol. , vol.10 , pp. 217-224
    • Perry, V.H.1    Holmes, C.2
  • 34
    • 0024317005 scopus 로고
    • Activation of the classical complement pathway in brain tissue of Alzheimer patients
    • 1:STN:280:DyaK3c7jslCksA%3D%3D 2559373
    • McGeer PL, Akiyama H, Itagaki S, McGeer EG. Activation of the classical complement pathway in brain tissue of Alzheimer patients. Neurosci Lett. 1989;107:341-6.
    • (1989) Neurosci Lett. , vol.107 , pp. 341-346
    • McGeer, P.L.1    Akiyama, H.2    Itagaki, S.3    McGeer, E.G.4
  • 35
    • 0001360461 scopus 로고
    • Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease
    • 1:STN:280:DyaK3c%2FhslGhug%3D%3D 2529544
    • Griffin WS, Stanley LC, Ling C, White L, MacLeod V, Perrot LJ, et al. Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease. Proc Natl Acad Sci U S A. 1989;86:7611-5.
    • (1989) Proc Natl Acad Sci U S A. , vol.86 , pp. 7611-7615
    • Griffin, W.S.1    Stanley, L.C.2    Ling, C.3    White, L.4    Macleod, V.5    Perrot, L.J.6
  • 37
    • 0037285379 scopus 로고    scopus 로고
    • Preliminary studies on Alzheimer's disease using cDNA microarrays
    • 1:CAS:528:DC%2BD3sXhs1agsr8%3D 12618014
    • Wang G, Zhang Y, Chen B, Cheng J. Preliminary studies on Alzheimer's disease using cDNA microarrays. Mech Ageing Dev. 2003;124:115-24.
    • (2003) Mech Ageing Dev. , vol.124 , pp. 115-124
    • Wang, G.1    Zhang, Y.2    Chen, B.3    Cheng, J.4
  • 38
    • 84872337044 scopus 로고    scopus 로고
    • Neuroinflammatory phenotype in early Alzheimer's disease
    • 1:CAS:528:DC%2BC38XhsVyqu73F 23062700
    • Sudduth TL, Schmitt FA, Nelson PT, Wilcock DM. Neuroinflammatory phenotype in early Alzheimer's disease. Neurobiol Aging. 2013;34:1051-9.
    • (2013) Neurobiol Aging. , vol.34 , pp. 1051-1059
    • Sudduth, T.L.1    Schmitt, F.A.2    Nelson, P.T.3    Wilcock, D.M.4
  • 39
    • 84865199264 scopus 로고    scopus 로고
    • Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: A microarray study
    • 1:CAS:528:DC%2BC38Xhsl2jt77P 22824372
    • Cribbs DH, Berchtold NC, Perreau V, Coleman PD, Rogers J, Tenner AJ, et al. Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study. J Neuroinflammation. 2012;9:179.
    • (2012) J Neuroinflammation. , vol.9 , pp. 179
    • Cribbs, D.H.1    Berchtold, N.C.2    Perreau, V.3    Coleman, P.D.4    Rogers, J.5    Tenner, A.J.6
  • 40
    • 1242341923 scopus 로고    scopus 로고
    • Incipient Alzheimer's disease: Microarray correlation analyses reveal major transcriptional and tumor suppressor responses
    • 1:CAS:528:DC%2BD2cXhs1SrsL4%3D 14769913
    • Blalock EM, Geddes JW, Chen KC, Porter NM, Markesbery WR, Landfield PW. Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses. Proc Natl Acad Sci U S A. 2004;101:2173-8.
    • (2004) Proc Natl Acad Sci U S A. , vol.101 , pp. 2173-2178
    • Blalock, E.M.1    Geddes, J.W.2    Chen, K.C.3    Porter, N.M.4    Markesbery, W.R.5    Landfield, P.W.6
  • 41
    • 78649573450 scopus 로고    scopus 로고
    • Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease
    • e13950 10.1371/journal.pone.0013950 2981526 21085570
    • Jones L, Holmans PA, Hamshere ML, Harold D, Moskvina V, Ivanov D, et al. Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease. PLoS One. 2010;5, e13950.
    • (2010) PLoS One. , vol.5
    • Jones, L.1    Holmans, P.A.2    Hamshere, M.L.3    Harold, D.4    Moskvina, V.5    Ivanov, D.6
  • 42
    • 84893745524 scopus 로고    scopus 로고
    • Identification of a unique TGF-beta-dependent molecular and functional signature in microglia
    • 1:CAS:528:DC%2BC3sXhvV2hsb%2FE 24316888
    • Butovsky O, Jedrychowski MP, Moore CS, Cialic R, Lanser AJ, Gabriely G, et al. Identification of a unique TGF-beta-dependent molecular and functional signature in microglia. Nat Neurosci. 2014;17:131-43.
    • (2014) Nat Neurosci. , vol.17 , pp. 131-143
    • Butovsky, O.1    Jedrychowski, M.P.2    Moore, C.S.3    Cialic, R.4    Lanser, A.J.5    Gabriely, G.6
  • 44
    • 61849124945 scopus 로고    scopus 로고
    • Overview on rodent models of Alzheimer's disease
    • Chapter 9:Unit 9.22
    • Dodart JC, May P. Overview on rodent models of Alzheimer's disease. Curr Protoc Neurosci. 2005;Chapter 9:Unit 9.22.
    • (2005) Curr Protoc Neurosci
    • Dodart, J.C.1    May, P.2
  • 45
    • 70349582720 scopus 로고    scopus 로고
    • Conversion of amyloid positive and negative MCI to AD over 3 years: An 11C-PIB PET study
    • 1:CAS:528:DC%2BD1MXhtVKrsbvF 19587325
    • Okello A, Koivunen J, Edison P, Archer HA, Turkheimer FE, Nagren K, et al. Conversion of amyloid positive and negative MCI to AD over 3 years: an 11C-PIB PET study. Neurology. 2009;73:754-60.
    • (2009) Neurology. , vol.73 , pp. 754-760
    • Okello, A.1    Koivunen, J.2    Edison, P.3    Archer, H.A.4    Turkheimer, F.E.5    Nagren, K.6
  • 46
    • 84872893030 scopus 로고    scopus 로고
    • Janus-faced microglia: Beneficial and detrimental consequences of microglial phagocytosis
    • 1:CAS:528:DC%2BC3sXht1ajtbfL 23386811
    • Sierra A, Abiega O, Shahraz A, Neumann H. Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis. Front Cell Neurosci. 2013;7:6.
    • (2013) Front Cell Neurosci. , vol.7 , pp. 6
    • Sierra, A.1    Abiega, O.2    Shahraz, A.3    Neumann, H.4
  • 47
    • 5044222305 scopus 로고    scopus 로고
    • Time-dependent reduction in Abeta levels after intracranial LPS administration in APP transgenic mice
    • 1:CAS:528:DC%2BD2cXotlClsb4%3D 15473997
    • Herber DL, Roth LM, Wilson D, Wilson N, Mason JE, Morgan D, et al. Time-dependent reduction in Abeta levels after intracranial LPS administration in APP transgenic mice. Exp Neurol. 2004;190:245-53.
    • (2004) Exp Neurol. , vol.190 , pp. 245-253
    • Herber, D.L.1    Roth, L.M.2    Wilson, D.3    Wilson, N.4    Mason, J.E.5    Morgan, D.6
  • 48
    • 34249899174 scopus 로고    scopus 로고
    • Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology
    • 1:CAS:528:DC%2BD2sXmsVWkurg%3D 17549256
    • Shaftel SS, Kyrkanides S, Olschowka JA, Miller JN, Johnson RE, O'Banion MK. Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology. J Clin Invest. 2007;117:1595-604.
    • (2007) J Clin Invest. , vol.117 , pp. 1595-1604
    • Shaftel, S.S.1    Kyrkanides, S.2    Olschowka, J.A.3    Miller, J.N.4    Johnson, R.E.5    O'Banion, M.K.6
  • 49
  • 50
    • 79961234274 scopus 로고    scopus 로고
    • Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease
    • 1:CAS:528:DC%2BC3MXhtVeis7nN 21813677
    • Mildner A, Schlevogt B, Kierdorf K, Bottcher C, Erny D, Kummer MP, et al. Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease. J Neurosci. 2011;31:11159-71.
    • (2011) J Neurosci. , vol.31 , pp. 11159-11171
    • Mildner, A.1    Schlevogt, B.2    Kierdorf, K.3    Bottcher, C.4    Erny, D.5    Kummer, M.P.6
  • 51
    • 78149438403 scopus 로고    scopus 로고
    • Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice
    • e13693 10.1371/journal.pone.0013693 2965160 21060874
    • Saederup N, Cardona AE, Croft K, Mizutani M, Cotleur AC, Tsou CL, et al. Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice. PLoS One. 2010;5, e13693.
    • (2010) PLoS One. , vol.5
    • Saederup, N.1    Cardona, A.E.2    Croft, K.3    Mizutani, M.4    Cotleur, A.C.5    Tsou, C.L.6
  • 52
    • 84900816904 scopus 로고    scopus 로고
    • Differential role of CCR2 in the dynamics of microglia and perivascular macrophages during prion disease
    • Gomez-Nicola D, Schetters ST, Perry VH. Differential role of CCR2 in the dynamics of microglia and perivascular macrophages during prion disease. Glia. 2014;62:1041-52.
    • (2014) Glia. , vol.62 , pp. 1041-1052
    • Gomez-Nicola, D.1    Schetters, S.T.2    Perry, V.H.3
  • 55
    • 51349085578 scopus 로고    scopus 로고
    • TREM2 is upregulated in amyloid plaque-associated microglia in aged APP23 transgenic mice
    • Frank S, Burbach GJ, Bonin M, Walter M, Streit W, Bechmann I, et al. TREM2 is upregulated in amyloid plaque-associated microglia in aged APP23 transgenic mice. Glia. 2008;56:1438-47.
    • (2008) Glia. , vol.56 , pp. 1438-1447
    • Frank, S.1    Burbach, G.J.2    Bonin, M.3    Walter, M.4    Streit, W.5    Bechmann, I.6
  • 57
    • 84924976223 scopus 로고    scopus 로고
    • Microglial dynamics and role in the healthy and diseased brain: A paradigm of functional plasticity
    • Gomez-Nicola D, Perry VH. Microglial dynamics and role in the healthy and diseased brain: a paradigm of functional plasticity. Neuroscientist. 2014;21(2):169-184.
    • (2014) Neuroscientist , vol.21 , Issue.2 , pp. 169-184
    • Gomez-Nicola, D.1    Perry, V.H.2
  • 58
    • 78149360132 scopus 로고    scopus 로고
    • Fate mapping analysis reveals that adult microglia derive from primitive macrophages
    • 1:CAS:528:DC%2BC3cXhtlKht7vP 20966214
    • Ginhoux F, Greter M, Leboeuf M, Nandi S, See P, Gokhan S, et al. Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science. 2010;330:841-5.
    • (2010) Science. , vol.330 , pp. 841-845
    • Ginhoux, F.1    Greter, M.2    Leboeuf, M.3    Nandi, S.4    See, P.5    Gokhan, S.6
  • 59
    • 36448994709 scopus 로고    scopus 로고
    • Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
    • 1:CAS:528:DC%2BD2sXhtlKltLbP 18026097
    • Ajami B, Bennett JL, Krieger C, Tetzlaff W, Rossi FM. Local self-renewal can sustain CNS microglia maintenance and function throughout adult life. Nat Neurosci. 2007;10:1538-43.
    • (2007) Nat Neurosci. , vol.10 , pp. 1538-1543
    • Ajami, B.1    Bennett, J.L.2    Krieger, C.3    Tetzlaff, W.4    Rossi, F.M.5
  • 60
    • 84873324231 scopus 로고    scopus 로고
    • Regulation of microglial proliferation during chronic neurodegeneration
    • 1:CAS:528:DC%2BC3sXhtlOjsrjJ 23392676
    • Gomez-Nicola D, Fransen NL, Suzzi S, Perry VH. Regulation of microglial proliferation during chronic neurodegeneration. J Neurosci. 2013;33:2481-93.
    • (2013) J Neurosci. , vol.33 , pp. 2481-2493
    • Gomez-Nicola, D.1    Fransen, N.L.2    Suzzi, S.3    Perry, V.H.4
  • 61
    • 42949175211 scopus 로고    scopus 로고
    • Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance
    • 1:CAS:528:DC%2BD1cXltVOnu7Y%3D 18417708
    • Bolmont T, Haiss F, Eicke D, Radde R, Mathis CA, Klunk WE, et al. Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance. J Neurosci. 2008;28:4283-92.
    • (2008) J Neurosci. , vol.28 , pp. 4283-4292
    • Bolmont, T.1    Haiss, F.2    Eicke, D.3    Radde, R.4    Mathis, C.A.5    Klunk, W.E.6
  • 62
    • 84856715245 scopus 로고    scopus 로고
    • Differential cell proliferation in the cortex of the APPswePS1dE9 Alzheimer's disease mouse model
    • Kamphuis W, Orre M, Kooijman L, Dahmen M, Hol EM. Differential cell proliferation in the cortex of the APPswePS1dE9 Alzheimer's disease mouse model. Glia. 2012;60:615-29.
    • (2012) Glia. , vol.60 , pp. 615-629
    • Kamphuis, W.1    Orre, M.2    Kooijman, L.3    Dahmen, M.4    Hol, E.M.5
  • 63
    • 84928493048 scopus 로고    scopus 로고
    • Analysis of microglial proliferation in Alzheimer's disease. Systems biology of Azlheimer's disease
    • Gomez-Nicola D, Perry VH. Analysis of microglial proliferation in Alzheimer's disease. Systems biology of Azlheimer's disease. Methods Mol Biol. in press.
    • Methods Mol Biol
    • Gomez-Nicola, D.1    Perry, V.H.2
  • 64
    • 70449534695 scopus 로고    scopus 로고
    • CNS infiltration of peripheral immune cells: D-Day for neurodegenerative disease?
    • Rezai-Zadeh K, Gate D, Town T. CNS infiltration of peripheral immune cells: D-Day for neurodegenerative disease? J Neuroimmune Pharmacol. 2009;4:462-75.
    • (2009) J Neuroimmune Pharmacol. , vol.4 , pp. 462-475
    • Rezai-Zadeh, K.1    Gate, D.2    Town, T.3
  • 65
    • 0025752360 scopus 로고
    • Phagocytosis of beta/A4 amyloid fibrils of the neuritic neocortical plaques
    • 1:STN:280:DyaK3MzhsVWkuw%3D%3D
    • Wisniewski HM, Barcikowska M, Kida E. Phagocytosis of beta/A4 amyloid fibrils of the neuritic neocortical plaques. Acta Neuropathol (Berl). 1991;81:588-90.
    • (1991) Acta Neuropathol (Berl). , vol.81 , pp. 588-590
    • Wisniewski, H.M.1    Barcikowska, M.2    Kida, E.3
  • 66
    • 84858794257 scopus 로고    scopus 로고
    • A novel Ly6C/Ly6G-based strategy to analyze the mouse splenic myeloid compartment
    • Rose S, Misharin A, Perlman H. A novel Ly6C/Ly6G-based strategy to analyze the mouse splenic myeloid compartment. Cytometry A. 2012;81:343-50.
    • (2012) Cytometry A. , vol.81 , pp. 343-350
    • Rose, S.1    Misharin, A.2    Perlman, H.3
  • 67
    • 0036200984 scopus 로고    scopus 로고
    • Occurrence of T cells in the brain of Alzheimer's disease and other neurological diseases
    • 1:CAS:528:DC%2BD38XhslWjtbc%3D 11958825
    • Togo T, Akiyama H, Iseki E, Kondo H, Ikeda K, Kato M, et al. Occurrence of T cells in the brain of Alzheimer's disease and other neurological diseases. J Neuroimmunol. 2002;124:83-92.
    • (2002) J Neuroimmunol. , vol.124 , pp. 83-92
    • Togo, T.1    Akiyama, H.2    Iseki, E.3    Kondo, H.4    Ikeda, K.5    Kato, M.6
  • 68
    • 0036849621 scopus 로고    scopus 로고
    • CD45 isoform alteration in CD4+ T cells as a potential diagnostic marker of Alzheimer's disease
    • 1:CAS:528:DC%2BD38XosFeru7Y%3D 12417447
    • Tan J, Town T, Abdullah L, Wu Y, Placzek A, Small B, et al. CD45 isoform alteration in CD4+ T cells as a potential diagnostic marker of Alzheimer's disease. J Neuroimmunol. 2002;132:164-72.
    • (2002) J Neuroimmunol. , vol.132 , pp. 164-172
    • Tan, J.1    Town, T.2    Abdullah, L.3    Wu, Y.4    Placzek, A.5    Small, B.6
  • 69
    • 0032964511 scopus 로고    scopus 로고
    • Characterization of cytokine production, screening of lymphocyte subset patterns and in vitro apoptosis in healthy and Alzheimer's Disease (AD) individuals
    • 1:CAS:528:DyaK1MXksVygtr4%3D 10408971
    • Lombardi VR, Garcia M, Rey L, Cacabelos R. Characterization of cytokine production, screening of lymphocyte subset patterns and in vitro apoptosis in healthy and Alzheimer's Disease (AD) individuals. J Neuroimmunol. 1999;97:163-71.
    • (1999) J Neuroimmunol. , vol.97 , pp. 163-171
    • Lombardi, V.R.1    Garcia, M.2    Rey, L.3    Cacabelos, R.4
  • 70
    • 0036949032 scopus 로고    scopus 로고
    • Regulation and function of class II major histocompatibility complex, CD40, and B7 expression in macrophages and microglia: Implications in neurological diseases
    • O'Keefe GM, Nguyen VT, Benveniste EN. Regulation and function of class II major histocompatibility complex, CD40, and B7 expression in macrophages and microglia: implications in neurological diseases. J Neurovirol. 2002;8:496-512.
    • (2002) J Neurovirol. , vol.8 , pp. 496-512
    • O'Keefe, G.M.1    Nguyen, V.T.2    Benveniste, E.N.3
  • 71
    • 0037393454 scopus 로고    scopus 로고
    • Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: A case report
    • 1:CAS:528:DC%2BD3sXisVOmu78%3D 12640446
    • Nicoll JA, Wilkinson D, Holmes C, Steart P, Markham H, Weller RO. Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report. Nat Med. 2003;9:448-52.
    • (2003) Nat Med. , vol.9 , pp. 448-452
    • Nicoll, J.A.1    Wilkinson, D.2    Holmes, C.3    Steart, P.4    Markham, H.5    Weller, R.O.6
  • 72
    • 10744230547 scopus 로고    scopus 로고
    • Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization
    • 1:CAS:528:DC%2BD3sXks1OktLk%3D 12847155
    • Orgogozo JM, Gilman S, Dartigues JF, Laurent B, Puel M, Kirby LC, et al. Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization. Neurology. 2003;61:46-54.
    • (2003) Neurology. , vol.61 , pp. 46-54
    • Orgogozo, J.M.1    Gilman, S.2    Dartigues, J.F.3    Laurent, B.4    Puel, M.5    Kirby, L.C.6
  • 73
    • 84893736391 scopus 로고    scopus 로고
    • Apolipoproteins e and J interfere with amyloid-beta uptake by primary human astrocytes and microglia in vitro
    • Mulder SD, Nielsen HM, Blankenstein MA, Eikelenboom P, Veerhuis R. Apolipoproteins E and J interfere with amyloid-beta uptake by primary human astrocytes and microglia in vitro. Glia. 2014;62:493-503.
    • (2014) Glia. , vol.62 , pp. 493-503
    • Mulder, S.D.1    Nielsen, H.M.2    Blankenstein, M.A.3    Eikelenboom, P.4    Veerhuis, R.5
  • 74
    • 84906716826 scopus 로고    scopus 로고
    • Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease
    • 1:CAS:528:DC%2BC2cXhtlKrtL3M 25129077
    • Lunnon K, Smith R, Hannon E, De Jager PL, Srivastava G, Volta M, et al. Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease. Nat Neurosci. 2014;17:1164-70.
    • (2014) Nat Neurosci. , vol.17 , pp. 1164-1170
    • Lunnon, K.1    Smith, R.2    Hannon, E.3    De Jager, P.L.4    Srivastava, G.5    Volta, M.6
  • 75
    • 79958109878 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha (TNF-alpha) and miRNA expression in frontal and temporal neocortex in Alzheimer's disease and the effect of TNF-alpha on miRNA expression in vitro
    • 3110390 1:CAS:528:DC%2BC3MXnsVGhsr4%3D 21686130
    • Culpan D, Kehoe PG, Love S. Tumour necrosis factor-alpha (TNF-alpha) and miRNA expression in frontal and temporal neocortex in Alzheimer's disease and the effect of TNF-alpha on miRNA expression in vitro. Int J Mol Epidemiol Genet. 2011;2:156-62.
    • (2011) Int J Mol Epidemiol Genet. , vol.2 , pp. 156-162
    • Culpan, D.1    Kehoe, P.G.2    Love, S.3
  • 76


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