Alveolar epithelial type II cells activate alveolar macrophages and mitigate P. aeruginosa infection

PLoS ONE

Volumn 4, Issue 3, 2009, Pages

  Kannan, Shibichakravarthy ^a   Huang, Huang ^a   Seeger, Drew ^a   Audet, Aaron ^a   Chen, Yaoyu ^b   Huang, Canhua ^c   Gao, Hongwei ^a   Li, Shaoguang ^b   Wu, Min ^a,c  

^a UNIVERSITY OF NORTH DAKOTA   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTRALIZING ANTIBODY; PROTEIN KINASE LYN; SUPEROXIDE; LYN PROTEIN-TYROSINE KINASE; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL PNEUMONIA; CELL ACTIVATION; CELL CULTURE; CELL FUNCTION; CELL TYPE; CELLULAR IMMUNITY; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION; HOST RESISTANCE; HUMAN; HUMAN TISSUE; LUNG ALVEOLUS EPITHELIUM; LUNG ALVEOLUS MACROPHAGE; MALE; MOUSE; NONHUMAN; PHAGOCYTOSIS; PROTEIN SECRETION; PSEUDOMONAS INFECTION; ANIMAL; C57BL MOUSE; CULTURE MEDIUM; CYTOLOGY; EPITHELIUM CELL; GENETICS; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; MOUSE MUTANT; PHYSIOLOGY; PSEUDOMONAS AERUGINOSA; RAT; RESPIRATORY TRACT MUCOSA;

BACTERIA (MICROORGANISMS); MUS;

ANIMALS; CELLS, CULTURED; CHEMOKINE CCL2; CULTURE MEDIA, CONDITIONED; EPITHELIAL CELLS; FEMALE; MACROPHAGES, ALVEOLAR; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NF-KAPPA B; PHAGOCYTOSIS; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; RATS; RESPIRATORY MUCOSA; SRC-FAMILY KINASES;

EID: 63349084911     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0004891     Document Type: Article

References (45)

1. Fehrenbach H (2001) Alveolar epithelial type II cell: defender of the alveolus revisited. Respir Res 2: 33-46.
2. Thorley AJ, Goldstraw P, Young A, Tetley TD (2005) Primary human alveolar type II epithelial cell CCL20 (macrophage inflammatory protein-3alpha)-induced dendritic cell migration. Am J Respir Cell Mol Biol 32: 262-267.
3. Sato K, Tomioka H, Shimizu T, Gonda T, Ota F, et al. (2002) Type II alveolar cells play roles in macrophage-mediated host innate resistance to pulmonary mycobacterial infections by producing proinflammatory cytokines. J Infect Dis 185: 1139-1147.
4. Amano H, Morimoto K, Senba M, Wang H, Ishida Y, et al. (2004) Essential contribution of monocyte chemoattractant protein-1/C-C chemokine ligand-2 to resolution and repair processes in acute bacterial pneumonia. J Immunol 172: 398-409.
5. Lo B, Hansen S, Evans K, Heath JK, Wright JR (2008) Alveolar epithelial type II cells induce T cell tolerance to specific antigen. J Immunol 180: 881-888.
6. Restrepo CI, Dong Q, Savov J, Mariencheck WI, Wright JR (1999) Surfactant protein D stimulates phagocytosis of Pseudomonas aeruginosa by alveolar macrophages. Am J Respir Cell Mol Biol 21: 576-585.
7. Burns JL, Gibson RL, McNamara S, Yim D, Emerson J, et al. (2001) Longitudinal assessment of Pseudomonas aeruginosa in young children with cystic fibrosis. J Infect Dis 183: 444-452.
8. LeVine AM, Kurak KE, Bruno MD, Stark JM, Whitsett JA, et al. (1998) Surfactant protein-A-deficient mice are susceptible to Pseudomonas aeruginosa infection. Am J Respir Cell Mol Biol 19: 700-708.
9. Mariencheck WI, Savov J, Dong Q, Tino MJ, Wright JR (1999) Surfactant protein A enhances alveolar macrophage phagocytosis of a live, mucoid strain of P. aeruginosa. Am J Physiol 277: L777-786.
10. Thorley AJ, Ford PA, Giembycz MA, Goldstraw P, Young A, et al. (2007) Differential regulation of cytokine release and leukocyte migration by lipopolysaccharide-stimulated primary human lung alveolar type II epithelial cells and macrophages. J Immunol 178: 463-473.
11. Das A, Boggaram V (2007) Proteasome dysfunction inhibits surfactant protein gene expression in lung epithelial cells: mechanism of inhibition of SP-B gene expression. Am J Physiol Lung Cell Mol Physiol 292: L74-84.
12. Kannan S, Audet A, Knittel J, Mullegama S, Gao GF, et al. (2006) Src kinase Lyn is crucial for Pseudomonas aeruginosa internalization into lung cells. European J Immunol 36: 1739-1752.
13. Kowalski MP, Pier GB (2004) Localization of cystic fibrosis transmembrane conductance regulator to lipid rafts of epithelial cells is required for Pseudomonas aeruginosa-induced cellular activation. J Immunol 172: 418-425.
14. Soong G, Reddy B, Sokol S, Adamo R, Prince A (2004) TLR2 is mobilized into an apical lipid raft receptor complex to signal infection in airway epithelial cells. J Clin Invest 113: 1482-1489.
15. Zaas D, Duncan M, Li G, Wright JR, Abraham SN (2005) Pseudomonas invasion of type I pneumocytes is dependent on the expression and phosphorylation of caveolin-2. J Biol Chem 280: 4864-4872.
16. Hauser AR, Engel JN (1999) Pseudomonas aeruginosa induces type-III-secretion-mediated apoptosis of macrophages and epithelial cells. Infect Immun 67: 5530-5537.
17. Kannan S, Audet A, Huang H, Chen LJ, Wu M (2008) Cholesterol-Rich Membrane Rafts and Lyn Are Involved in Phagocytosis during Pseudomonas aeruginosa Infection. J Immunol 180: 2396-2408.
18. Grassme H, Jendrossek V, Riehle A, von Kurthy G, Berger J, et al. (2003) Host defense against Pseudomonas aeruginosa requires ceramide-rich membrane rafts. Nat Med 9: 322-330.
19. Lafont F, Abrami L, van der Goot FG (2004) Bacterial subversion of lipid rafts. Curr Opin Microbiol 7: 4-10.
20. Kay JG, Murray RZ, Pagan JK, Stow JL (2006) Cytokine secretion via cholesterol-rich lipid raft-associated SNAREs at the phagocytic cup. J Biol Chem 281: 11949-11954.
21. Zhou Y, Ling EA, Dheen ST (2007) Dexamethasone suppresses monocyte chemoattractant protein-1 production via mitogen activated protein kinase phosphatase-1 dependent inhibition of Jun N-terminal kinase and p38 mitogen-activated protein kinase in activated rat microglia. J Neurochem 102: 667-678.
22. Subramanian A, Hegde S, Correll PH, Paulson RF (2006) Mutation of the Lyn tyrosine kinase delays the progression of Friend virus induced erythroleukemia without affecting susceptibility. Leuk Res 30: 1141-1149.
23. Zhu QS, Xia L, Mills GB, Lowell CA, Touw IP, et al. (2006) G-CSF induced reactive oxygen species involves Lyn-PI3-kinase-Akt and contributes to myeloid cell growth. Blood 107: 1847-1856.
24. Kierbel A, Gassama-Diagne A, Mostov K, Engel JN (2005) The phosphoinositol-3-kinase-protein kinase B/Akt pathway is critical for Pseudomonas aeruginosa strain PAK internalization. Mol Biol Cell 16: 2577-2585.
25. Hoyal CR, Gutierrez A, Young BM, Catz SD, Lin JH, et al. (2003) Modulation of p47PHOX activity by site-specific phosphorylation: Akt-dependent activation of the NADPH oxidase. Proc Natl Acad Sci U S A 100: 5130-5135.
26. Fitzer-Attas CJ, Lowry M, Crowley MT, Finn AJ, Meng F, et al. (2000) Fcgamma receptor-mediated phagocytosis in macrophages lacking the Src family tyrosine kinases Hck, Fgr, and Lyn. J Exp Med 191: 669-682.
27. Neff TA, Guo RF, Neff SB, Sarma JV, Speyer CL, et al. (2005) Relationship of acute lung inflammatory injury to Fas/FasL system. Am J Pathol 166: 685-694.
28. Baran CP, Tridandapani S, Helgason CD, Humphries RK, Krystal G, et al. (2003) The inositol 5′-phosphatase SHIP-1 and the Src kinase Lyn negatively regulate macrophage colony-stimulating factor-induced Akt activity. J Biol Chem 278: 38628-38636.
29. Kamen LA, Levinsohn J, Cadwallader A, Tridandapani S, Swanson JA (2008) SHIP-1 increases early oxidative burst and regulates phagosome maturation in macrophages. J Immunol 180: 7497-7505.
30. Maresso AW, Baldwin MR, Barbieri JT (2004) Ezrin/radixin/moesin proteins are high affinity targets for ADP-ribosylation by Pseudomonas aeruginosa ExoS. J Biol Chem 279: 38402-38408.
31. Chan VW, Meng F, Soriano P, DeFranco AL, Lowell CA (1997) Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation. Immunity 7: 69-81.
32. Hu Y, Liu Y, Pelletier S, Buchdunger E, Warmuth M, et al. (2004) Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia. Nat Genet 36: 453-461.
33. Lu B, Rutledge BJ, Gu L, Fiorillo J, Lukacs NW, et al. (1998) Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice. J Exp Med 187: 601-608.
34. Dobbs LG (1990) Isolation and culture of alveolar type II cells. Am J Physiol Lung Cell Mol Physiol 258: L134-147.
35. Kannan S, Pang H, Foster D, Rao Z, Wu M (2006) Human 8-oxoguanine DNA glycosylase links MAPK activation to resistance to hyperoxia in lung epithelial cells. Cell Death Differ 13: 311-323.
36. Wu M, Hussain S, He HY, Pasula R, Smith PA, et al. (2001) Genetically engineered macrophages expressing IFN-γ restore alveolar immune function in scid mice. Proc Natl Acad Sci U S A 98: 14589-14594.
37. Wisniowski PE, Spech RW, Wu M, Doyle NA, Pasula R, et al. (2000) Vitronectin protects alveolar macrophages from silica toxicity. Am J Respir Crit Care Med 162: 733-739.
38. Stover CK, Pham XQ, Erwin AL, Mizoguchi SD, Warrener P, et al. (2000) Complete genome sequence of Pseudomonas aeruginosa PA01, an opportunistic pathogen. Nature 406: 959-964.
39. Preston MJ, Seed PC, Toder DS, Iglewski BH, Ohman DE, et al. (1997) Contribution of proteases and LasR to the virulence of Pseudomonas aeruginosa during corneal infections. Infect Immun 65: 3086-3090.
40. Miyata S, Casey M, Frank DW, Ausubel FM, Drenkard E (2003) Use of the Galleria mellonella caterpillar as a model host to study the role of the type III secretion system in Pseudomonas aeruginosa pathogenesis. Infect Immun 71: 2404-2013.
41. Wu M, Brown WL, Stockley PG (1995) Cell-specific delivery of bacteriophage-encapsidated ricin A chain. Bioconjugate Chem 6: 587-595.
42. Wu M, Stockley PG, Martin II WJ (2002) An improved Western blotting effectively reduces the background. Electrophoresis 23: 2373-2376.
43. O'Brien AD, Standiford TJ, Christensen PJ, Wilcoxen SE, Paine Rr (1998) Chemotaxis of alveolar macrophages in response to signals derived from alveolar epithelial cells. J Lab Clin Med 131: 391-392.
44. Drannik AG, Pouladi MA, Robbins CS, Goncharova SI, Kianpour S, et al. (2004) Impact of cigarette smoke on clearance and inflammation after Pseudomonas aeruginosa infection. Am J Respir Crit Care Med 170: 1164-1171.
45. Steinhauser ML, Hogaboam CM, Kunkel SL, Lukacs NW, Strieter RM, et al. (1999) IL-10 is a major mediator of sepsis-induced impairment in lung antibacterial host defense. J Immunol 162: 392-399.