The endothelium-derived contracting factor uridine adenosine tetraphosphate induces P2Y 2-mediated pro-inflammatory signaling by monocyte chemoattractant protein-1 formation

Journal of Molecular Medicine

Volumn 89, Issue 8, 2011, Pages 799-810

  Schuchardt, Mirjam ^a,b   Prüfer, Jasmin ^a,b   Prüfer, Nicole ^a   Wiedon, Annette ^a   Huang, Tao ^a   Chebli, Miriam ^a   Jankowski, Vera ^a   Jankowski, Joachim ^a   Schäfer Korting, Monika ^b   Zidek, Walter ^a   Van Der Giet, Markus ^a   Tölle, Markus ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Endothelium; Inflammation; Monocyte chemoattractant protein 1; Oxidative stress; P2Y; Pro inflammatory response; Purinergic; Purinoceptor; Reactive oxygen species; Up 4A

Indexed keywords

APOCYNIN; DIPHENYLIODONIUM SALT; ENDOTHELIUM DERIVED CONSTRICTING FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; PHOSPHATE; PROTEIN P47; PURINERGIC P2X RECEPTOR; PURINERGIC P2Y2 RECEPTOR; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; UNCLASSIFIED DRUG; URIDINE ADENOSINE TETRAPHOSPHATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ATHEROGENESIS; CELL MEMBRANE; CELL MIGRATION; CONTROLLED STUDY; CYTOSOL; ENDOTHELIUM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; INFLAMMATION; MONOCYTE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; RAT; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE;

ANIMALS; CELL MOVEMENT; CHEMOKINE CCL2; DINUCLEOSIDE PHOSPHATES; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; INFLAMMATION MEDIATORS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MONOCYTES; MYOCYTES, SMOOTH MUSCLE; NADH, NADPH OXIDOREDUCTASES; NITRATES; NITRITES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RAC1 GTP-BINDING PROTEIN; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RECEPTORS, PURINERGIC P2Y2; SIGNAL TRANSDUCTION;

EID: 80052430198     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-011-0750-6     Document Type: Article

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