High glucose enhances MMP-2 production in adventitial fibroblasts via Akt1-dependent NF-κB pathway

FEBS Letters

Volumn 581, Issue 22, 2007, Pages 4189-4194

  Lee, Seung Jin ^a,b   Bae, Sun Sik ^a,b   Kim, Koan Hoi ^a   Lee, Won Suk ^a,b   Rhim, Byung Yong ^a   Hong, Ki Whan ^b   Kim, Chi Dae ^a,b  

^a Pusan National University   (South Korea)

^b Pusan National University   (South Korea)

Author keywords

Adventitial fibroblasts; High glucose; Matrix metalloproteinase 2; NF B; PI3K Akt1

Indexed keywords

GELATINASE A; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; OLIGODEOXYNUCLEOTIDE DERIVATIVE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; TRANSCRIPTION FACTOR AP 1;

ADVENTITIA; ANALYTIC METHOD; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FIBROBLAST; GEL MOBILITY SHIFT ASSAY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; VASCULAR DISEASE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CONNECTIVE TISSUE; ENZYME ACTIVATION; ENZYME INDUCTION; FIBROBLASTS; GLUCOSE; ISOENZYMES; MATRIX METALLOPROTEINASE 2; MICE; NF-KAPPA B; OLIGODEOXYRIBONUCLEOTIDES; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 34548124866     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2007.07.058     Document Type: Article

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