Hematopoietic stem cell quiescence and function are controlled by the CYLD-TRAF2-p38MAPK pathway

Journal of Experimental Medicine

Volumn 212, Issue 4, 2015, Pages 525-538

  Tesio, Melania ^a,b   Tang, Yilang ^d   Müdder, Katja ^a   Saini, Massimo ^a   Von Paleske, Lisa ^a   Macintyre, Elizabeth ^e   Pasparakis, Manolis ^c   Waisman, Ari ^d   Trumpp, Andreas ^a,b  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b Exp Hematology Group Heidelberg Institute for Stem Cell Technology and Experimental Medicine GGmbH   (Germany)

^c UNIVERSITY OF COLOGNE   (Germany)

^d JOHANNES GUTENBERG UNIVERSITY   (Germany)

^e INSTITUT NECKER ENFANTS MALADES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; DEUBIQUITINASE; I KAPPA B; MITOGEN ACTIVATED PROTEIN KINASE P38; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; CYLD PROTEIN, MOUSE; CYSTEINE PROTEINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

ADENOID CYSTIC CARCINOMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL MUTANT; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; FLOW CYTOMETRY; GENE LOSS; HEMATOPOIETIC STEM CELL; MOUSE; MULTIPOTENT STEM CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE; UPREGULATION; ANIMAL; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; MUTATION;

ANIMALS; CYSTEINE ENDOPEPTIDASES; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELLS; MAP KINASE SIGNALING SYSTEM; MICE; MICE, KNOCKOUT; MUTATION; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; TNF RECEPTOR-ASSOCIATED FACTOR 2;

EID: 84928243697     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20141438     Document Type: Article

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