Pten loss in the bone marrow leads to G-CSF-mediated HSC mobilization

Journal of Experimental Medicine

Volumn 210, Issue 11, 2013, Pages 2337-2349

  Tesio, Tmelania ^a,b   Oser, Gabriela M ^a,c   Baccelli, Irène ^a,b   Blanco Bose, William ^c   Wu, Hong ^d   Göthert, Joachim R ^e   Kogan, Scott C ^f   Trumpp, Andreas ^a,b,c  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b Heidelberg Institute for Stem Cell Technology and Experimental Medicine   (Germany)

^c EPFL   (Switzerland)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY HOSPITAL ESSEN   (Germany)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B;

ACUTE LYMPHOBLASTIC LEUKEMIA; ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; BONE MARROW CELL; CELL CYCLE; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; CELL RENEWAL; CELL SURVIVAL; CELLULAR SECRETION; CONTROLLED STUDY; CYTOKINE PRODUCTION; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC SYSTEM; LEUKEMIA; MOUSE; MYELOPROLIFERATIVE DISORDER; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; SPLEEN; SPLENOMEGALY; STEM CELL MOBILIZATION; STROMA CELL; UPREGULATION;

ALLELES; ANIMALS; BONE MARROW; CYTOKINES; GENE DELETION; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELL MOBILIZATION; HEMATOPOIETIC STEM CELLS; INTEGRASES; MICE; MYELOPROLIFERATIVE DISORDERS; PHENOTYPE; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; SPLEEN;

EID: 84886860011     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20122768     Document Type: Article

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