-
1
-
-
84863520113
-
RNAi screen identifies MAPK14 as a druggable suppressor of human hematopoietic stem cell expansion
-
A. Baudet, C. Karlsson, M. Safaee Talkhoncheh, R. Galeev, M. Magnusson, and J. Larsson RNAi screen identifies MAPK14 as a druggable suppressor of human hematopoietic stem cell expansion Blood 119 2012 6255 6258
-
(2012)
Blood
, vol.119
, pp. 6255-6258
-
-
Baudet, A.1
Karlsson, C.2
Safaee Talkhoncheh, M.3
Galeev, R.4
Magnusson, M.5
Larsson, J.6
-
2
-
-
84897574744
-
Gadd45a regulates hematopoietic stem cell stress responses in mice
-
Y. Chen, X. Ma, M. Zhang, X. Wang, C. Wang, H. Wang, P. Guo, W. Yuan, K.L. Rudolph, Q. Zhan, and Z. Ju Gadd45a regulates hematopoietic stem cell stress responses in mice Blood 123 2014 851 862
-
(2014)
Blood
, vol.123
, pp. 851-862
-
-
Chen, Y.1
Ma, X.2
Zhang, M.3
Wang, X.4
Wang, C.5
Wang, H.6
Guo, P.7
Yuan, W.8
Rudolph, K.L.9
Zhan, Q.10
Ju, Z.11
-
3
-
-
0034613735
-
In vitro self-renewal division of hematopoietic stem cells
-
H. Ema, H. Takano, K. Sudo, and H. Nakauchi In vitro self-renewal division of hematopoietic stem cells J. Exp. Med. 192 2000 1281 1288
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1281-1288
-
-
Ema, H.1
Takano, H.2
Sudo, K.3
Nakauchi, H.4
-
4
-
-
84886680488
-
GATA-3 regulates the self-renewal of long-term hematopoietic stem cells
-
C. Frelin, R. Herrington, S. Janmohamed, M. Barbara, G. Tran, C.J. Paige, P. Benveniste, J.C. Zuñiga-Pflücker, A. Souabni, M. Busslinger, and N.N. Iscove GATA-3 regulates the self-renewal of long-term hematopoietic stem cells Nat. Immunol. 14 2013 1037 1044
-
(2013)
Nat. Immunol.
, vol.14
, pp. 1037-1044
-
-
Frelin, C.1
Herrington, R.2
Janmohamed, S.3
Barbara, M.4
Tran, G.5
Paige, C.J.6
Benveniste, P.7
Zuñiga-Pflücker, J.C.8
Souabni, A.9
Busslinger, M.10
Iscove, N.N.11
-
5
-
-
71449125977
-
Forcing cells to change lineages
-
T. Graf, and T. Enver Forcing cells to change lineages Nature 462 2009 587 594
-
(2009)
Nature
, vol.462
, pp. 587-594
-
-
Graf, T.1
Enver, T.2
-
6
-
-
0034744537
-
Gadd45γ is dispensable for normal mouse development and T-cell proliferation
-
DOI 10.1128/MCB.21.9.3137-3143.2001
-
A. Hoffmeyer, R. Piekorz, R. Moriggl, and J.N. Ihle Gadd45gamma is dispensable for normal mouse development and T-cell proliferation Mol. Cell. Biol. 21 2001 3137 3143 (Pubitemid 32298380)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.9
, pp. 3137-3143
-
-
Hoffmeyer, A.1
Piekorz, R.2
Moriggl, R.3
Ihle, J.N.4
-
7
-
-
33645730667
-
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
-
K. Ito, A. Hirao, F. Arai, K. Takubo, S. Matsuoka, K. Miyamoto, M. Ohmura, K. Naka, K. Hosokawa, Y. Ikeda, and T. Suda Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells Nat. Med. 12 2006 446 451
-
(2006)
Nat. Med.
, vol.12
, pp. 446-451
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
Takubo, K.4
Matsuoka, S.5
Miyamoto, K.6
Ohmura, M.7
Naka, K.8
Hosokawa, K.9
Ikeda, Y.10
Suda, T.11
-
8
-
-
73949103238
-
The transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesis
-
A. Kimura, M.A. Rieger, J.M. Simone, W. Chen, M.C. Wickre, B.M. Zhu, P.S. Hoppe, J.J. O'Shea, T. Schroeder, and L. Hennighausen The transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesis Blood 114 2009 4721 4728
-
(2009)
Blood
, vol.114
, pp. 4721-4728
-
-
Kimura, A.1
Rieger, M.A.2
Simone, J.M.3
Chen, W.4
Wickre, M.C.5
Zhu, B.M.6
Hoppe, P.S.7
O'Shea, J.J.8
Schroeder, T.9
Hennighausen, L.10
-
9
-
-
83255187529
-
Gadd45 stress sensors in malignancy and leukemia
-
D.A. Liebermann, J.S. Tront, X. Sha, K. Mukherjee, A. Mohamed-Hadley, and B. Hoffman Gadd45 stress sensors in malignancy and leukemia Crit. Rev. Oncog. 16 2011 129 140
-
(2011)
Crit. Rev. Oncog.
, vol.16
, pp. 129-140
-
-
Liebermann, D.A.1
Tront, J.S.2
Sha, X.3
Mukherjee, K.4
Mohamed-Hadley, A.5
Hoffman, B.6
-
10
-
-
0034743912
-
H1 cells
-
DOI 10.1016/S1074-7613(01)00141-8
-
B. Lu, H. Yu, C. Chow, B. Li, W. Zheng, R.J. Davis, and R.A. Flavell GADD45gamma mediates the activation of the p38 and JNK MAP kinase pathways and cytokine production in effector TH1 cells Immunity 14 2001 583 590 (Pubitemid 32520869)
-
(2001)
Immunity
, vol.14
, Issue.5
, pp. 583-590
-
-
Lu, B.1
Yu, H.2
Chow, C.-W.3
Li, B.4
Zheng, W.-P.5
Davis, R.J.6
Flavell, R.A.7
-
11
-
-
38349157811
-
Hematopoietic cytokines
-
D. Metcalf Hematopoietic cytokines Blood 111 2008 485 491
-
(2008)
Blood
, vol.111
, pp. 485-491
-
-
Metcalf, D.1
-
12
-
-
0036275374
-
Regulation of MTK1/MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding
-
DOI 10.1128/MCB.22.13.4544-4555.2002
-
H. Mita, J. Tsutsui, M. Takekawa, E.A. Witten, and H. Saito Regulation of MTK1/MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding Mol. Cell. Biol. 22 2002 4544 4555 (Pubitemid 34620392)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.13
, pp. 4544-4555
-
-
Mita, H.1
Tsutsui, J.2
Takekawa, M.3
Witten, E.A.4
Saito, H.5
-
13
-
-
83855164048
-
Gadd45 proteins: Relevance to aging, longevity and age-related pathologies
-
A.A. Moskalev, Z. Smit-McBride, M.V. Shaposhnikov, E.N. Plyusnina, A. Zhavoronkov, A. Budovsky, R. Tacutu, and V.E. Fraifeld Gadd45 proteins: relevance to aging, longevity and age-related pathologies Ageing Res. Rev. 11 2012 51 66
-
(2012)
Ageing Res. Rev.
, vol.11
, pp. 51-66
-
-
Moskalev, A.A.1
Smit-Mcbride, Z.2
Shaposhnikov, M.V.3
Plyusnina, E.N.4
Zhavoronkov, A.5
Budovsky, A.6
Tacutu, R.7
Fraifeld, V.E.8
-
14
-
-
84877787762
-
M-CSF instructs myeloid lineage fate in single haematopoietic stem cells
-
N. Mossadegh-Keller, S. Sarrazin, P.K. Kandalla, L. Espinosa, E.R. Stanley, S.L. Nutt, J. Moore, and M.H. Sieweke M-CSF instructs myeloid lineage fate in single haematopoietic stem cells Nature 497 2013 239 243
-
(2013)
Nature
, vol.497
, pp. 239-243
-
-
Mossadegh-Keller, N.1
Sarrazin, S.2
Kandalla, P.K.3
Espinosa, L.4
Stanley, E.R.5
Nutt, S.L.6
Moore, J.7
Sieweke, M.H.8
-
15
-
-
34247106718
-
Near-maximal expansions of hematopoietic stem cells in culture using NUP98-HOX fusions
-
DOI 10.1016/j.exphem.2007.02.012, PII S0301472X0700118X
-
H. Ohta, S. Sekulovic, S. Bakovic, C.J. Eaves, N. Pineault, M. Gasparetto, C. Smith, G. Sauvageau, and R.K. Humphries Near-maximal expansions of hematopoietic stem cells in culture using NUP98-HOX fusions Exp. Hematol. 35 2007 817 830 (Pubitemid 46601757)
-
(2007)
Experimental Hematology
, vol.35
, Issue.5
, pp. 817-830
-
-
Ohta, H.1
Sekulovic, S.2
Bakovic, S.3
Eaves, C.J.4
Pineault, N.5
Gasparetto, M.6
Smith, C.7
Sauvageau, G.8
Humphries, R.K.9
-
16
-
-
39349096526
-
Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
-
DOI 10.1016/j.cell.2008.01.025, PII S0092867408001256
-
S.H. Orkin, and L.I. Zon Hematopoiesis: an evolving paradigm for stem cell biology Cell 132 2008 631 644 (Pubitemid 351260057)
-
(2008)
Cell
, vol.132
, Issue.4
, pp. 631-644
-
-
Orkin, S.H.1
Zon, L.I.2
-
17
-
-
70349253985
-
Analyzing cell fate control by cytokines through continuous single cell biochemistry
-
M.A. Rieger, and T. Schroeder Analyzing cell fate control by cytokines through continuous single cell biochemistry J. Cell. Biochem. 108 2009 343 352
-
(2009)
J. Cell. Biochem.
, vol.108
, pp. 343-352
-
-
Rieger, M.A.1
Schroeder, T.2
-
18
-
-
67650418221
-
Hematopoietic cytokines can instruct lineage choice
-
M.A. Rieger, P.S. Hoppe, B.M. Smejkal, A.C. Eitelhuber, and T. Schroeder Hematopoietic cytokines can instruct lineage choice Science 325 2009 217 218
-
(2009)
Science
, vol.325
, pp. 217-218
-
-
Rieger, M.A.1
Hoppe, P.S.2
Smejkal, B.M.3
Eitelhuber, A.C.4
Schroeder, T.5
-
19
-
-
21544467270
-
Cell intrinsic alterations underlie hematopoietic stem cell aging
-
DOI 10.1073/pnas.0503280102
-
D.J. Rossi, D. Bryder, J.M. Zahn, H. Ahlenius, R. Sonu, A.J. Wagers, and I.L. Weissman Cell intrinsic alterations underlie hematopoietic stem cell aging Proc. Natl. Acad. Sci. USA 102 2005 9194 9199 (Pubitemid 40923540)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.26
, pp. 9194-9199
-
-
Rossi, D.J.1
Bryder, D.2
Zahn, J.M.3
Ahlenius, H.4
Sonu, R.5
Wagers, A.J.6
Weissman, I.L.7
-
20
-
-
67650590934
-
MafB restricts M-CSF-dependent myeloid commitment divisions of hematopoietic stem cells
-
S. Sarrazin, N. Mossadegh-Keller, T. Fukao, A. Aziz, F. Mourcin, L. Vanhille, L. Kelly Modis, P. Kastner, S. Chan, and E. Duprez et al. MafB restricts M-CSF-dependent myeloid commitment divisions of hematopoietic stem cells Cell 138 2009 300 313
-
(2009)
Cell
, vol.138
, pp. 300-313
-
-
Sarrazin, S.1
Mossadegh-Keller, N.2
Fukao, T.3
Aziz, A.4
Mourcin, F.5
Vanhille, L.6
Kelly Modis, L.7
Kastner, P.8
Chan, S.9
Duprez, E.10
-
21
-
-
44349132633
-
The crystal structure and dimerization interface of GADD45γ
-
DOI 10.1073/pnas.0800086105
-
J.D. Schrag, S. Jiralerspong, M. Banville, M.L. Jaramillo, and M.D. O'Connor-McCourt The crystal structure and dimerization interface of GADD45gamma Proc. Natl. Acad. Sci. USA 105 2008 6566 6571 (Pubitemid 351754547)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.18
, pp. 6566-6571
-
-
Schrag, J.D.1
Jiralerspong, S.2
Banville, M.3
Jaramillo, M.L.4
O'Connor-McCourt, M.D.5
-
22
-
-
33749023927
-
2-terminal kinase and p38 stress signaling resulting in apoptosis and senescence
-
DOI 10.1158/0008-5472.CAN-06-2013
-
J.S. Tront, B. Hoffman, and D.A. Liebermann Gadd45a suppresses Ras-driven mammary tumorigenesis by activation of c-Jun NH2-terminal kinase and p38 stress signaling resulting in apoptosis and senescence Cancer Res. 66 2006 8448 8454 (Pubitemid 44449156)
-
(2006)
Cancer Research
, vol.66
, Issue.17
, pp. 8448-8454
-
-
Tront, J.S.1
Hoffman, B.2
Liebermann, D.A.3
-
23
-
-
77649119006
-
Awakening dormant haematopoietic stem cells
-
A. Trumpp, M. Essers, and A. Wilson Awakening dormant haematopoietic stem cells Nat. Rev. Immunol. 10 2010 201 209
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 201-209
-
-
Trumpp, A.1
Essers, M.2
Wilson, A.3
-
24
-
-
0036324977
-
GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress
-
DOI 10.1002/jcp.10140
-
M. Vairapandi, A.G. Balliet, B. Hoffman, and D.A. Liebermann GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress J. Cell. Physiol. 192 2002 327 338 (Pubitemid 34827609)
-
(2002)
Journal of Cellular Physiology
, vol.192
, Issue.3
, pp. 327-338
-
-
Vairapandi, M.1
Balliet, A.G.2
Hoffman, B.3
Liebermann, D.A.4
-
25
-
-
84863229585
-
A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage
-
J. Wang, Q. Sun, Y. Morita, H. Jiang, A. Gross, A. Lechel, K. Hildner, L.M. Guachalla, A. Gompf, and D. Hartmann et al. A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage Cell 148 2012 1001 1014
-
(2012)
Cell
, vol.148
, pp. 1001-1014
-
-
Wang, J.1
Sun, Q.2
Morita, Y.3
Jiang, H.4
Gross, A.5
Lechel, A.6
Hildner, K.7
Guachalla, L.M.8
Gompf, A.9
Hartmann, D.10
-
26
-
-
2542455620
-
Stepwise reprogramming of B cells into macrophages
-
DOI 10.1016/S0092-8674(04)00419-2, PII S0092867404004192
-
H. Xie, M. Ye, R. Feng, and T. Graf Stepwise reprogramming of B cells into macrophages Cell 117 2004 663 676 (Pubitemid 38692531)
-
(2004)
Cell
, vol.117
, Issue.5
, pp. 663-676
-
-
Xie, H.1
Ye, M.2
Feng, R.3
Graf, T.4
-
27
-
-
0033517293
-
CR6: A third member in the MyD118 and Gadd45 gene family which functions in negative growth control
-
DOI 10.1038/sj.onc.1202885
-
W. Zhang, I. Bae, K. Krishnaraju, N. Azam, W. Fan, K. Smith, B. Hoffman, and D.A. Liebermann CR6: A third member in the MyD118 and Gadd45 gene family which functions in negative growth control Oncogene 18 1999 4899 4907 (Pubitemid 29425296)
-
(1999)
Oncogene
, vol.18
, Issue.35
, pp. 4899-4907
-
-
Zhang, W.1
Bae, I.2
Krishnaraju, K.3
Azam, N.4
Fan, W.5
Smith, K.6
Hoffman, B.7
Liebermann, D.A.8
-
28
-
-
84862829412
-
Inhibition of p38 MAPK activity promotes ex vivo expansion of human cord blood hematopoietic stem cells
-
J. Zou, P. Zou, J. Wang, L. Li, Y. Wang, D. Zhou, and L. Liu Inhibition of p38 MAPK activity promotes ex vivo expansion of human cord blood hematopoietic stem cells Ann. Hematol. 91 2012 813 823
-
(2012)
Ann. Hematol.
, vol.91
, pp. 813-823
-
-
Zou, J.1
Zou, P.2
Wang, J.3
Li, L.4
Wang, Y.5
Zhou, D.6
Liu, L.7
|