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Volumn 14, Issue 5, 2015, Pages 518-531

Apathy in Parkinson's disease: Clinical features, neural substrates, diagnosis, and treatment

Author keywords

[No Author keywords available]

Indexed keywords

AMITRIPTYLINE; CITALOPRAM; LEVODOPA; METHYLPHENIDATE; MIRTAZAPINE; PRAMIPEXOLE; RACLOPRIDE C 11; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR;

EID: 84928039067     PISSN: 14744422     EISSN: 14744465     Source Type: Journal    
DOI: 10.1016/S1474-4422(15)00019-8     Document Type: Review
Times cited : (378)

References (157)
  • 2
    • 33745595886 scopus 로고    scopus 로고
    • Apathy and the functional anatomy of the prefrontal cortex-basal ganglia circuits
    • Levy R, Dubois B Apathy and the functional anatomy of the prefrontal cortex-basal ganglia circuits. Cereb Cortex 2006, 16:916-928.
    • (2006) Cereb Cortex , vol.16 , pp. 916-928
    • Levy, R.1    Dubois, B.2
  • 3
    • 0002397145 scopus 로고    scopus 로고
    • Apathy: concept, syndrome, neural mechanisms, and treatment
    • Marin RS Apathy: concept, syndrome, neural mechanisms, and treatment. Semin Clin Neuropsychiatry 1996, 1:304-314.
    • (1996) Semin Clin Neuropsychiatry , vol.1 , pp. 304-314
    • Marin, R.S.1
  • 4
    • 84856950829 scopus 로고    scopus 로고
    • Apathy in Parkinson's disease: diagnostic and etiological dilemmas
    • Starkstein SE Apathy in Parkinson's disease: diagnostic and etiological dilemmas. Mov Disord 2012, 27:174-178.
    • (2012) Mov Disord , vol.27 , pp. 174-178
    • Starkstein, S.E.1
  • 5
  • 8
    • 84918591929 scopus 로고    scopus 로고
    • Apathy in untreated early-stage Parkinson disease: relationship with other non-motor symptoms
    • Dujardin K, Langlois C, Plomhause L, et al. Apathy in untreated early-stage Parkinson disease: relationship with other non-motor symptoms. Mov Disord 2014, 29:1796-1801.
    • (2014) Mov Disord , vol.29 , pp. 1796-1801
    • Dujardin, K.1    Langlois, C.2    Plomhause, L.3
  • 9
    • 2442680422 scopus 로고    scopus 로고
    • Long term effects of bilateral subthalamic nucleus stimulation on cognitive function, mood, and behaviour in Parkinson's disease
    • Funkiewiez A, Ardouin C, Caputo E, et al. Long term effects of bilateral subthalamic nucleus stimulation on cognitive function, mood, and behaviour in Parkinson's disease. J Neurol Neurosurg Psychiatry 2004, 75:834-839.
    • (2004) J Neurol Neurosurg Psychiatry , vol.75 , pp. 834-839
    • Funkiewiez, A.1    Ardouin, C.2    Caputo, E.3
  • 11
    • 0034284172 scopus 로고    scopus 로고
    • Negative symptoms: the 'pathology' of motivation and goal-directed behaviour
    • Brown RG, Pluck G Negative symptoms: the 'pathology' of motivation and goal-directed behaviour. Trends Neurosci 2000, 23:412-417.
    • (2000) Trends Neurosci , vol.23 , pp. 412-417
    • Brown, R.G.1    Pluck, G.2
  • 15
    • 0019188610 scopus 로고
    • From motivation to action: functional interface between the limbic system and the motor system
    • Mogenson GJ, Jones DL, Yim CY From motivation to action: functional interface between the limbic system and the motor system. Prog Neurobiol 1980, 14:69-97.
    • (1980) Prog Neurobiol , vol.14 , pp. 69-97
    • Mogenson, G.J.1    Jones, D.L.2    Yim, C.Y.3
  • 16
    • 77957184093 scopus 로고
    • Akinetic mutism with an epidermoid cyst of the 3rd ventricle
    • Cairns H, Olfield RC, Pennybacker JB, Whitteridge D Akinetic mutism with an epidermoid cyst of the 3rd ventricle. Brain 1941, 64:273-290.
    • (1941) Brain , vol.64 , pp. 273-290
    • Cairns, H.1    Olfield, R.C.2    Pennybacker, J.B.3    Whitteridge, D.4
  • 17
    • 0000568548 scopus 로고
    • Etudes sur les complications et les sequelles mentales de l'encephalite epidemique
    • Naville F Etudes sur les complications et les sequelles mentales de l'encephalite epidemique. Encephale 1922, 17:369-375.
    • (1922) Encephale , vol.17 , pp. 369-375
    • Naville, F.1
  • 19
    • 84855529386 scopus 로고    scopus 로고
    • Dysfunction of fronto-limbic brain circuitry in depression
    • Liao C, Feng Z, Zhou D, et al. Dysfunction of fronto-limbic brain circuitry in depression. Neuroscience 2012, 201:231-238.
    • (2012) Neuroscience , vol.201 , pp. 231-238
    • Liao, C.1    Feng, Z.2    Zhou, D.3
  • 20
    • 0000877290 scopus 로고    scopus 로고
    • Willed action and its impairments
    • Jahanshahi M Willed action and its impairments. Cogn Neuropsychol 1998, 15:483-533.
    • (1998) Cogn Neuropsychol , vol.15 , pp. 483-533
    • Jahanshahi, M.1
  • 21
    • 57749202002 scopus 로고    scopus 로고
    • Three before their time: neuroscientists whose ideas were ignored by their contemporaries
    • Gross CG Three before their time: neuroscientists whose ideas were ignored by their contemporaries. Exp Brain Res 2009, 192:321-334.
    • (2009) Exp Brain Res , vol.192 , pp. 321-334
    • Gross, C.G.1
  • 23
    • 0035470397 scopus 로고    scopus 로고
    • Auto-activation deficit: a basal ganglia related syndrome
    • Laplane D, Dubois B Auto-activation deficit: a basal ganglia related syndrome. Mov Disord 2001, 16:810-814.
    • (2001) Mov Disord , vol.16 , pp. 810-814
    • Laplane, D.1    Dubois, B.2
  • 24
    • 0030904732 scopus 로고    scopus 로고
    • The anatomical relationships of the prefrontal cortex with limbic structures and the basal ganglia
    • Groenewegen HJ, Wright CI, Uylings HB The anatomical relationships of the prefrontal cortex with limbic structures and the basal ganglia. J Psychopharmacol 1997, 11:99-106.
    • (1997) J Psychopharmacol , vol.11 , pp. 99-106
    • Groenewegen, H.J.1    Wright, C.I.2    Uylings, H.B.3
  • 26
    • 84894544413 scopus 로고    scopus 로고
    • Loss of dopaminergic nigrostriatal neurons accounts for the motivational and affective deficits in Parkinson's disease
    • Drui G, Carnicella S, Carcenac C, et al. Loss of dopaminergic nigrostriatal neurons accounts for the motivational and affective deficits in Parkinson's disease. Mol Psychiatry 2014, 19:358-367.
    • (2014) Mol Psychiatry , vol.19 , pp. 358-367
    • Drui, G.1    Carnicella, S.2    Carcenac, C.3
  • 27
    • 34247469020 scopus 로고    scopus 로고
    • Dopamine neuron systems in the brain: an update
    • Björklund A, Dunnett SB Dopamine neuron systems in the brain: an update. Trends Neurosci 2007, 30:194-202.
    • (2007) Trends Neurosci , vol.30 , pp. 194-202
    • Björklund, A.1    Dunnett, S.B.2
  • 28
    • 0030952816 scopus 로고    scopus 로고
    • Neuropsychological and neuroimaging evidence for the involvement of the frontal lobes in depression
    • Goodwin GM Neuropsychological and neuroimaging evidence for the involvement of the frontal lobes in depression. J Psychopharmacol 1997, 11:115-122.
    • (1997) J Psychopharmacol , vol.11 , pp. 115-122
    • Goodwin, G.M.1
  • 29
    • 0032944684 scopus 로고    scopus 로고
    • Reciprocal limbic-cortical function and negative mood: converging PET findings in depression and normal sadness
    • Mayberg HS, Liotti M, Brannan SK, et al. Reciprocal limbic-cortical function and negative mood: converging PET findings in depression and normal sadness. Am J Psychiatry 1999, 156:675-682.
    • (1999) Am J Psychiatry , vol.156 , pp. 675-682
    • Mayberg, H.S.1    Liotti, M.2    Brannan, S.K.3
  • 30
    • 38649134764 scopus 로고    scopus 로고
    • A final common pathway for depression? Progress toward a general conceptual framework
    • Stone EA, Lin Y, Quartermain D A final common pathway for depression? Progress toward a general conceptual framework. Neurosci Biobehav Rev 2008, 32:508-524.
    • (2008) Neurosci Biobehav Rev , vol.32 , pp. 508-524
    • Stone, E.A.1    Lin, Y.2    Quartermain, D.3
  • 31
    • 0343145706 scopus 로고    scopus 로고
    • Effect of sertraline on regional metabolic rate in patients with affective disorder
    • Buchsbaum MS, Wu J, Siegel BV, et al. Effect of sertraline on regional metabolic rate in patients with affective disorder. Biol Psychiatry 1997, 41:15-22.
    • (1997) Biol Psychiatry , vol.41 , pp. 15-22
    • Buchsbaum, M.S.1    Wu, J.2    Siegel, B.V.3
  • 32
    • 0034667295 scopus 로고    scopus 로고
    • Regional metabolic effects of fluoxetine in major depression: serial changes and relationship to clinical response
    • Mayberg HS, Brannan SK, Tekell JL, et al. Regional metabolic effects of fluoxetine in major depression: serial changes and relationship to clinical response. Biol Psychiatry 2000, 48:830-843.
    • (2000) Biol Psychiatry , vol.48 , pp. 830-843
    • Mayberg, H.S.1    Brannan, S.K.2    Tekell, J.L.3
  • 33
    • 34548648044 scopus 로고    scopus 로고
    • Assessment of the progression of Parkinson's disease: a metabolic network approach
    • Eckert T, Tang C, Eidelberg D Assessment of the progression of Parkinson's disease: a metabolic network approach. Lancet Neurol 2007, 6:926-932.
    • (2007) Lancet Neurol , vol.6 , pp. 926-932
    • Eckert, T.1    Tang, C.2    Eidelberg, D.3
  • 35
    • 10644258699 scopus 로고    scopus 로고
    • Athymhormia and disorders of motivation in Basal Ganglia disease
    • Habib M Athymhormia and disorders of motivation in Basal Ganglia disease. J Neuropsychiatry Clin Neurosci 2004, 16:509-524.
    • (2004) J Neuropsychiatry Clin Neurosci , vol.16 , pp. 509-524
    • Habib, M.1
  • 36
    • 0034212432 scopus 로고    scopus 로고
    • Cognitive and emotional influences in anterior cingulate cortex
    • Bush G, Luu P, Posner MI Cognitive and emotional influences in anterior cingulate cortex. Trends Cogn Sci 2000, 4:215-222.
    • (2000) Trends Cogn Sci , vol.4 , pp. 215-222
    • Bush, G.1    Luu, P.2    Posner, M.I.3
  • 37
    • 78851471555 scopus 로고    scopus 로고
    • Emotional processing in anterior cingulate and medial prefrontal cortex
    • Etkin A, Egner T, Kalisch R Emotional processing in anterior cingulate and medial prefrontal cortex. Trends Cogn Sci 2011, 15:85-93.
    • (2011) Trends Cogn Sci , vol.15 , pp. 85-93
    • Etkin, A.1    Egner, T.2    Kalisch, R.3
  • 38
    • 84892379361 scopus 로고    scopus 로고
    • Similar roles of substantia nigra and ventral tegmental dopamine neurons in reward and aversion
    • Ilango A, Kesner AJ, Keller KL, Stuber GD, Bonci A, Ikemoto S Similar roles of substantia nigra and ventral tegmental dopamine neurons in reward and aversion. J Neurosci 2014, 34:817-822.
    • (2014) J Neurosci , vol.34 , pp. 817-822
    • Ilango, A.1    Kesner, A.J.2    Keller, K.L.3    Stuber, G.D.4    Bonci, A.5    Ikemoto, S.6
  • 39
    • 0028816344 scopus 로고
    • Functional anatomy of the basal ganglia. I. The cortico-basal ganglia-thalamo-cortical loop
    • Parent A, Hazrati LN Functional anatomy of the basal ganglia. I. The cortico-basal ganglia-thalamo-cortical loop. Brain Res Brain Res Rev 1995, 20:91-127.
    • (1995) Brain Res Brain Res Rev , vol.20 , pp. 91-127
    • Parent, A.1    Hazrati, L.N.2
  • 40
    • 0032780070 scopus 로고    scopus 로고
    • Functional and anatomical relationships among the amygdala, basal forebrain, ventral striatum, and cortex. An integrative discussion
    • Gray TS Functional and anatomical relationships among the amygdala, basal forebrain, ventral striatum, and cortex. An integrative discussion. Ann N Y Acad Sci 1999, 877:439-444.
    • (1999) Ann N Y Acad Sci , vol.877 , pp. 439-444
    • Gray, T.S.1
  • 41
    • 84922268526 scopus 로고    scopus 로고
    • The onset of nonmotor symptoms in Parkinson's disease (The ONSET PD Study)
    • Pont-Sunyer C, Hotter A, Gaig C, et al. The onset of nonmotor symptoms in Parkinson's disease (The ONSET PD Study). Mov Disord 2014, 30:229-237.
    • (2014) Mov Disord , vol.30 , pp. 229-237
    • Pont-Sunyer, C.1    Hotter, A.2    Gaig, C.3
  • 42
    • 67849094320 scopus 로고    scopus 로고
    • The spectrum of neuropsychiatric symptoms in patients with early untreated Parkinson's disease
    • Aarsland D, Brønnick K, Alves G, et al. The spectrum of neuropsychiatric symptoms in patients with early untreated Parkinson's disease. J Neurol Neurosurg Psychiatry 2009, 80:928-930.
    • (2009) J Neurol Neurosurg Psychiatry , vol.80 , pp. 928-930
    • Aarsland, D.1    Brønnick, K.2    Alves, G.3
  • 43
    • 69949153066 scopus 로고    scopus 로고
    • The PRIAMO study: a multicenter assessment of nonmotor symptoms and their impact on quality of life in Parkinson's disease
    • Barone P, Antonini A, Colosimo C, et al. The PRIAMO study: a multicenter assessment of nonmotor symptoms and their impact on quality of life in Parkinson's disease. Mov Disord 2009, 24:1641-1649.
    • (2009) Mov Disord , vol.24 , pp. 1641-1649
    • Barone, P.1    Antonini, A.2    Colosimo, C.3
  • 44
    • 84922089121 scopus 로고    scopus 로고
    • Apathy in untreated, de novo patients with Parkinson's disease: validation study of Apathy Evaluation Scale
    • Santangelo G, Barone P, Cuoco S, et al. Apathy in untreated, de novo patients with Parkinson's disease: validation study of Apathy Evaluation Scale. J Neurol 2014, 261:2319-2328.
    • (2014) J Neurol , vol.261 , pp. 2319-2328
    • Santangelo, G.1    Barone, P.2    Cuoco, S.3
  • 45
    • 34249040495 scopus 로고    scopus 로고
    • Characteristics of apathy in Parkinson's disease
    • Dujardin K, Sockeel P, Devos D, et al. Characteristics of apathy in Parkinson's disease. Mov Disord 2007, 22:778-784.
    • (2007) Mov Disord , vol.22 , pp. 778-784
    • Dujardin, K.1    Sockeel, P.2    Devos, D.3
  • 48
    • 33846016934 scopus 로고    scopus 로고
    • Neuropsychiatric symptoms in patients with Parkinson's disease and dementia: frequency, profile and associated care giver stress
    • Aarsland D, Brønnick K, Ehrt U, et al. Neuropsychiatric symptoms in patients with Parkinson's disease and dementia: frequency, profile and associated care giver stress. J Neurol Neurosurg Psychiatry 2007, 78:36-42.
    • (2007) J Neurol Neurosurg Psychiatry , vol.78 , pp. 36-42
    • Aarsland, D.1    Brønnick, K.2    Ehrt, U.3
  • 50
    • 73949158743 scopus 로고    scopus 로고
    • Apathy may herald cognitive decline and dementia in Parkinson's disease
    • Dujardin K, Sockeel P, Delliaux M, Destee A, Defebvre L Apathy may herald cognitive decline and dementia in Parkinson's disease. Mov Disord 2009, 24:2391-2397.
    • (2009) Mov Disord , vol.24 , pp. 2391-2397
    • Dujardin, K.1    Sockeel, P.2    Delliaux, M.3    Destee, A.4    Defebvre, L.5
  • 51
    • 64249116690 scopus 로고    scopus 로고
    • Prevalence and clinical correlates of apathy in Parkinson's disease: a community-based study
    • Pedersen KF, Larsen JP, Alves G, Aarsland D Prevalence and clinical correlates of apathy in Parkinson's disease: a community-based study. Parkinsonism Relat Disord 2009, 15:295-299.
    • (2009) Parkinsonism Relat Disord , vol.15 , pp. 295-299
    • Pedersen, K.F.1    Larsen, J.P.2    Alves, G.3    Aarsland, D.4
  • 52
    • 84874814200 scopus 로고    scopus 로고
    • Apathy is associated with activities of daily living ability in Parkinson's disease
    • Laatu S, Karrasch M, Martikainen K, Marttila R Apathy is associated with activities of daily living ability in Parkinson's disease. Dement Geriatr Cogn Disord 2013, 35:249-255.
    • (2013) Dement Geriatr Cogn Disord , vol.35 , pp. 249-255
    • Laatu, S.1    Karrasch, M.2    Martikainen, K.3    Marttila, R.4
  • 54
    • 84875152647 scopus 로고    scopus 로고
    • Predictors of discrepancies in Parkinson's disease patient and caregiver ratings of apathy, disinhibition, and executive dysfunction before and after diagnosis
    • Schiehser DM, Liu L, Lessig SL, et al. Predictors of discrepancies in Parkinson's disease patient and caregiver ratings of apathy, disinhibition, and executive dysfunction before and after diagnosis. J Int Neuropsychol Soc 2013, 19:295-304.
    • (2013) J Int Neuropsychol Soc , vol.19 , pp. 295-304
    • Schiehser, D.M.1    Liu, L.2    Lessig, S.L.3
  • 55
    • 84888637323 scopus 로고    scopus 로고
    • Are apathy and depression independently associated with longitudinal trajectories of cortical atrophy in mild cognitive impairment?
    • the Alzheimer's Disease Neuroimaging Initiative
    • Zahodne LB, Gongvatana A, Cohen RA, Ott BR, Tremont G Are apathy and depression independently associated with longitudinal trajectories of cortical atrophy in mild cognitive impairment?. Am J Geriatr Psychiatry 2013, 21:1098-1106. the Alzheimer's Disease Neuroimaging Initiative.
    • (2013) Am J Geriatr Psychiatry , vol.21 , pp. 1098-1106
    • Zahodne, L.B.1    Gongvatana, A.2    Cohen, R.A.3    Ott, B.R.4    Tremont, G.5
  • 57
    • 58349105525 scopus 로고    scopus 로고
    • Parkinson's disease dementia: definitions, guidelines, and research perspectives in diagnosis
    • Goetz CG, Emre M, Dubois B Parkinson's disease dementia: definitions, guidelines, and research perspectives in diagnosis. Ann Neurol 2008, 64(suppl 2):S81-S92.
    • (2008) Ann Neurol , vol.64 , pp. S81-S92
    • Goetz, C.G.1    Emre, M.2    Dubois, B.3
  • 58
    • 84869109864 scopus 로고    scopus 로고
    • Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice
    • Luk KC, Kehm V, Carroll J, et al. Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice. Science 2012, 338:949-953.
    • (2012) Science , vol.338 , pp. 949-953
    • Luk, K.C.1    Kehm, V.2    Carroll, J.3
  • 59
    • 0036523714 scopus 로고    scopus 로고
    • Clinical, neuropsychological, and morphometric correlates of apathy in Parkinson's disease
    • Isella V, Melzi P, Grimaldi M, et al. Clinical, neuropsychological, and morphometric correlates of apathy in Parkinson's disease. Mov Disord 2002, 17:366-371.
    • (2002) Mov Disord , vol.17 , pp. 366-371
    • Isella, V.1    Melzi, P.2    Grimaldi, M.3
  • 61
    • 77956867133 scopus 로고    scopus 로고
    • Facial emotion recognition impairment in patients with Parkinson's disease and isolated apathy
    • Martinez-Corral M, Pagonabarraga J, Llebaria G, et al. Facial emotion recognition impairment in patients with Parkinson's disease and isolated apathy. Parkinsons Dis 2010, 2010:930627.
    • (2010) Parkinsons Dis , vol.2010 , pp. 930627
    • Martinez-Corral, M.1    Pagonabarraga, J.2    Llebaria, G.3
  • 62
    • 84908338902 scopus 로고    scopus 로고
    • Apathy and impaired emotional facial recognition networks overlap in Parkinson's disease: a PET study with conjunction analyses
    • Robert G, Le Jeune F, Dondaine T, et al. Apathy and impaired emotional facial recognition networks overlap in Parkinson's disease: a PET study with conjunction analyses. J Neurol Neurosurg Psychiatry 2014, 85:1153-1158.
    • (2014) J Neurol Neurosurg Psychiatry , vol.85 , pp. 1153-1158
    • Robert, G.1    Le Jeune, F.2    Dondaine, T.3
  • 63
    • 0030453470 scopus 로고    scopus 로고
    • Acute effects of levodopa on neuropsychological performance in stable and fluctuating Parkinson's disease patients at different levodopa plasma levels
    • Kulisevsky J, Avila A, Barbanoj M, Antonijoan R, Berthier ML, Gironell A Acute effects of levodopa on neuropsychological performance in stable and fluctuating Parkinson's disease patients at different levodopa plasma levels. Brain 1996, 119:2121-2132.
    • (1996) Brain , vol.119 , pp. 2121-2132
    • Kulisevsky, J.1    Avila, A.2    Barbanoj, M.3    Antonijoan, R.4    Berthier, M.L.5    Gironell, A.6
  • 64
    • 0037707632 scopus 로고    scopus 로고
    • L-Dopa medication remediates cognitive inflexibility, but increases impulsivity in patients with Parkinson's disease
    • Cools R, Barker RA, Sahakian BJ, Robbins TW L-Dopa medication remediates cognitive inflexibility, but increases impulsivity in patients with Parkinson's disease. Neuropsychologia 2003, 41:1431-1441.
    • (2003) Neuropsychologia , vol.41 , pp. 1431-1441
    • Cools, R.1    Barker, R.A.2    Sahakian, B.J.3    Robbins, T.W.4
  • 65
    • 79960240326 scopus 로고    scopus 로고
    • Ventral striatal and medial prefrontal BOLD activation is correlated with reward-related electrocortical activity: a combined ERP and fMRI study
    • Carlson JM, Foti D, Mujica-Parodi LR, Harmon-Jones E, Hajcak G Ventral striatal and medial prefrontal BOLD activation is correlated with reward-related electrocortical activity: a combined ERP and fMRI study. Neuroimage 2011, 57:1608-1616.
    • (2011) Neuroimage , vol.57 , pp. 1608-1616
    • Carlson, J.M.1    Foti, D.2    Mujica-Parodi, L.R.3    Harmon-Jones, E.4    Hajcak, G.5
  • 66
    • 84899488694 scopus 로고    scopus 로고
    • Apathy in Parkinson's disease: neurophysiological evidence of impaired incentive processing
    • Martinez-Horta S, Riba J, de Bobadilla RF, et al. Apathy in Parkinson's disease: neurophysiological evidence of impaired incentive processing. J Neurosci 2014, 34:5918-5926.
    • (2014) J Neurosci , vol.34 , pp. 5918-5926
    • Martinez-Horta, S.1    Riba, J.2    de Bobadilla, R.F.3
  • 67
    • 84870934207 scopus 로고    scopus 로고
    • Unique effects of apathy and depression signs on cognition and function in amnestic mild cognitive impairment
    • Zahodne LB, Tremont G Unique effects of apathy and depression signs on cognition and function in amnestic mild cognitive impairment. Int J Geriatr Psychiatry 2013, 28:50-56.
    • (2013) Int J Geriatr Psychiatry , vol.28 , pp. 50-56
    • Zahodne, L.B.1    Tremont, G.2
  • 68
    • 84855614148 scopus 로고    scopus 로고
    • Clinical correlates of apathy in patients recently diagnosed with Parkinson's disease: the ANIMO study
    • the ANIMO Study Group
    • Cubo E, Benito-León J, Coronell C, Armesto D Clinical correlates of apathy in patients recently diagnosed with Parkinson's disease: the ANIMO study. Neuroepidemiology 2012, 38:48-55. the ANIMO Study Group.
    • (2012) Neuroepidemiology , vol.38 , pp. 48-55
    • Cubo, E.1    Benito-León, J.2    Coronell, C.3    Armesto, D.4
  • 69
    • 57049117070 scopus 로고    scopus 로고
    • Apathy and anhedonia rating scales in Parkinson's disease: critique and recommendations
    • Leentjens AF, Dujardin K, Marsh L, et al. Apathy and anhedonia rating scales in Parkinson's disease: critique and recommendations. Mov Disord 2008, 23:2004-2014.
    • (2008) Mov Disord , vol.23 , pp. 2004-2014
    • Leentjens, A.F.1    Dujardin, K.2    Marsh, L.3
  • 70
    • 57049168125 scopus 로고    scopus 로고
    • Anxiety rating scales in Parkinson's disease: critique and recommendations
    • Leentjens AF, Dujardin K, Marsh L, et al. Anxiety rating scales in Parkinson's disease: critique and recommendations. Mov Disord 2008, 23:2015-2025.
    • (2008) Mov Disord , vol.23 , pp. 2015-2025
    • Leentjens, A.F.1    Dujardin, K.2    Marsh, L.3
  • 71
    • 34447554375 scopus 로고    scopus 로고
    • Depression rating scales in Parkinson's disease: critique and recommendations
    • Schrag A, Barone P, Brown RG, et al. Depression rating scales in Parkinson's disease: critique and recommendations. Mov Disord 2007, 22:1077-1092.
    • (2007) Mov Disord , vol.22 , pp. 1077-1092
    • Schrag, A.1    Barone, P.2    Brown, R.G.3
  • 72
    • 0022351034 scopus 로고
    • Severe disturbance of higher cognition after bilateral frontal lobe ablation: patient EVR
    • Eslinger PJ, Damasio AR Severe disturbance of higher cognition after bilateral frontal lobe ablation: patient EVR. Neurology 1985, 35:1731-1741.
    • (1985) Neurology , vol.35 , pp. 1731-1741
    • Eslinger, P.J.1    Damasio, A.R.2
  • 73
    • 0027978063 scopus 로고
    • The behavioural and motor consequences of focal lesions of the basal ganglia in man
    • Bhatia KP, Marsden CD The behavioural and motor consequences of focal lesions of the basal ganglia in man. Brain 1994, 117:859-876.
    • (1994) Brain , vol.117 , pp. 859-876
    • Bhatia, K.P.1    Marsden, C.D.2
  • 75
    • 0032837272 scopus 로고    scopus 로고
    • Range of neuropsychiatric disturbances in patients with Parkinson's disease
    • Aarsland D, Larsen JP, Lim NG, et al. Range of neuropsychiatric disturbances in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry 1999, 67:492-496.
    • (1999) J Neurol Neurosurg Psychiatry , vol.67 , pp. 492-496
    • Aarsland, D.1    Larsen, J.P.2    Lim, N.G.3
  • 76
    • 84863711814 scopus 로고    scopus 로고
    • Different apathy profile in behavioral variant of frontotemporal dementia and Alzheimer's disease: a preliminary investigation
    • Quaranta D, Marra C, Rossi C, Gainotti G, Masullo C Different apathy profile in behavioral variant of frontotemporal dementia and Alzheimer's disease: a preliminary investigation. Curr Gerontol Geriatr Res 2012, 2012:719250.
    • (2012) Curr Gerontol Geriatr Res , vol.2012 , pp. 719250
    • Quaranta, D.1    Marra, C.2    Rossi, C.3    Gainotti, G.4    Masullo, C.5
  • 78
    • 0035114397 scopus 로고    scopus 로고
    • Neuropsychiatric differences between Parkinson's disease with dementia and Alzheimer's disease
    • Aarsland D, Cummings JL, Larsen JP Neuropsychiatric differences between Parkinson's disease with dementia and Alzheimer's disease. Int J Geriatr Psychiatry 2001, 16:184-191.
    • (2001) Int J Geriatr Psychiatry , vol.16 , pp. 184-191
    • Aarsland, D.1    Cummings, J.L.2    Larsen, J.P.3
  • 79
    • 0037097225 scopus 로고    scopus 로고
    • Brain perfusion in Alzheimer's disease with and without apathy: a SPECT study with statistical parametric mapping analysis
    • Benoit M, Koulibaly PM, Migneco O, Darcourt J, Pringuey DJ, Robert PH Brain perfusion in Alzheimer's disease with and without apathy: a SPECT study with statistical parametric mapping analysis. Psychiatry Res 2002, 114:103-111.
    • (2002) Psychiatry Res , vol.114 , pp. 103-111
    • Benoit, M.1    Koulibaly, P.M.2    Migneco, O.3    Darcourt, J.4    Pringuey, D.J.5    Robert, P.H.6
  • 82
    • 17944362144 scopus 로고    scopus 로고
    • Perfusion brain SPECT and statistical parametric mapping analysis indicate that apathy is a cingulate syndrome: a study in Alzheimer's disease and nondemented patients
    • Migneco O, Benoit M, Koulibaly PM, et al. Perfusion brain SPECT and statistical parametric mapping analysis indicate that apathy is a cingulate syndrome: a study in Alzheimer's disease and nondemented patients. Neuroimage 2001, 13:896-902.
    • (2001) Neuroimage , vol.13 , pp. 896-902
    • Migneco, O.1    Benoit, M.2    Koulibaly, P.M.3
  • 83
    • 77950817597 scopus 로고    scopus 로고
    • Non-motor dopamine withdrawal syndrome after surgery for Parkinson's disease: predictors and underlying mesolimbic denervation
    • Thobois S, Ardouin C, Lhommée E, et al. Non-motor dopamine withdrawal syndrome after surgery for Parkinson's disease: predictors and underlying mesolimbic denervation. Brain 2010, 133:1111-1127.
    • (2010) Brain , vol.133 , pp. 1111-1127
    • Thobois, S.1    Ardouin, C.2    Lhommée, E.3
  • 84
    • 20444477480 scopus 로고    scopus 로고
    • Depression in Parkinson's disease: loss of dopamine and noradrenaline innervation in the limbic system
    • Remy P, Doder M, Lees A, Turjanski N, Brooks D Depression in Parkinson's disease: loss of dopamine and noradrenaline innervation in the limbic system. Brain 2005, 128:1314-1322.
    • (2005) Brain , vol.128 , pp. 1314-1322
    • Remy, P.1    Doder, M.2    Lees, A.3    Turjanski, N.4    Brooks, D.5
  • 85
    • 84922394507 scopus 로고    scopus 로고
    • Preoperative factors of apathy in subthalamic stimulated Parkinson disease: a PET study
    • Robert GH, Le Jeune F, Lozachmeur C, et al. Preoperative factors of apathy in subthalamic stimulated Parkinson disease: a PET study. Neurology 2014, 83:1620-1626.
    • (2014) Neurology , vol.83 , pp. 1620-1626
    • Robert, G.H.1    Le Jeune, F.2    Lozachmeur, C.3
  • 86
    • 0034059124 scopus 로고    scopus 로고
    • Emotion, decision making and the orbitofrontal cortex
    • Bechara A, Damasio H, Damasio AR Emotion, decision making and the orbitofrontal cortex. Cereb Cortex 2000, 10:295-307.
    • (2000) Cereb Cortex , vol.10 , pp. 295-307
    • Bechara, A.1    Damasio, H.2    Damasio, A.R.3
  • 87
    • 84878261050 scopus 로고    scopus 로고
    • Rotigotine and specific non-motor symptoms of Parkinson's disease: post hoc analysis of RECOVER
    • Chaudhuri KR, Martinez-Martin P, Antonini A, et al. Rotigotine and specific non-motor symptoms of Parkinson's disease: post hoc analysis of RECOVER. Parkinsonism Relat Disord 2013, 19:660-665.
    • (2013) Parkinsonism Relat Disord , vol.19 , pp. 660-665
    • Chaudhuri, K.R.1    Martinez-Martin, P.2    Antonini, A.3
  • 88
    • 66549083459 scopus 로고    scopus 로고
    • Increased striatal dopamine release in Parkinsonian patients with pathological gambling: a [11C] raclopride PET study
    • Steeves TD, Miyasaki J, Zurowski M, et al. Increased striatal dopamine release in Parkinsonian patients with pathological gambling: a [11C] raclopride PET study. Brain 2009, 132:1376-1385.
    • (2009) Brain , vol.132 , pp. 1376-1385
    • Steeves, T.D.1    Miyasaki, J.2    Zurowski, M.3
  • 89
    • 78649506636 scopus 로고    scopus 로고
    • Drug-induced deactivation of inhibitory networks predicts pathological gambling in PD
    • van Eimeren T, Pellecchia G, Cilia R, et al. Drug-induced deactivation of inhibitory networks predicts pathological gambling in PD. Neurology 2010, 75:1711-1716.
    • (2010) Neurology , vol.75 , pp. 1711-1716
    • van Eimeren, T.1    Pellecchia, G.2    Cilia, R.3
  • 90
    • 84872686587 scopus 로고    scopus 로고
    • Clinical features of dopamine agonist withdrawal syndrome in a movement disorders clinic
    • Pondal M, Marras C, Miyasaki J, et al. Clinical features of dopamine agonist withdrawal syndrome in a movement disorders clinic. J Neurol Neurosurg Psychiatry 2013, 84:130-135.
    • (2013) J Neurol Neurosurg Psychiatry , vol.84 , pp. 130-135
    • Pondal, M.1    Marras, C.2    Miyasaki, J.3
  • 91
    • 84860626797 scopus 로고    scopus 로고
    • Subthalamic stimulation in Parkinson's disease: restoring the balance of motivated behaviours
    • Lhommée E, Klinger H, Thobois S, et al. Subthalamic stimulation in Parkinson's disease: restoring the balance of motivated behaviours. Brain 2012, 135:1463-1477.
    • (2012) Brain , vol.135 , pp. 1463-1477
    • Lhommée, E.1    Klinger, H.2    Thobois, S.3
  • 92
    • 84894103907 scopus 로고    scopus 로고
    • Mood and behavioural effects of subthalamic stimulation in Parkinson's disease
    • Castrioto A, Lhommée E, Moro E, Krack P Mood and behavioural effects of subthalamic stimulation in Parkinson's disease. Lancet Neurol 2014, 13:287-305.
    • (2014) Lancet Neurol , vol.13 , pp. 287-305
    • Castrioto, A.1    Lhommée, E.2    Moro, E.3    Krack, P.4
  • 93
    • 74949088519 scopus 로고    scopus 로고
    • Dopamine agonist withdrawal syndrome in Parkinson disease
    • Rabinak CA, Nirenberg MJ Dopamine agonist withdrawal syndrome in Parkinson disease. Arch Neurol 2010, 67:58-63.
    • (2010) Arch Neurol , vol.67 , pp. 58-63
    • Rabinak, C.A.1    Nirenberg, M.J.2
  • 95
    • 33845874647 scopus 로고    scopus 로고
    • Cortical activity in Parkinson's disease during executive processing depends on striatal involvement
    • Monchi O, Petrides M, Mejia-Constain B, Strafella AP Cortical activity in Parkinson's disease during executive processing depends on striatal involvement. Brain 2007, 130:233-244.
    • (2007) Brain , vol.130 , pp. 233-244
    • Monchi, O.1    Petrides, M.2    Mejia-Constain, B.3    Strafella, A.P.4
  • 96
    • 84874256990 scopus 로고    scopus 로고
    • Neuroimaging markers of motor and nonmotor features of Parkinson's disease: an 18f fluorodeoxyglucose positron emission computed tomography study
    • Huang C, Ravdin LD, Nirenberg MJ, et al. Neuroimaging markers of motor and nonmotor features of Parkinson's disease: an 18f fluorodeoxyglucose positron emission computed tomography study. Dement Geriatr Cogn Disord 2013, 35:183-196.
    • (2013) Dement Geriatr Cogn Disord , vol.35 , pp. 183-196
    • Huang, C.1    Ravdin, L.D.2    Nirenberg, M.J.3
  • 97
    • 73349128759 scopus 로고    scopus 로고
    • Subthalamic nucleus stimulation in Parkinson disease induces apathy: a PET study
    • Le Jeune F, Drapier D, Bourguignon A, et al. Subthalamic nucleus stimulation in Parkinson disease induces apathy: a PET study. Neurology 2009, 73:1746-1751.
    • (2009) Neurology , vol.73 , pp. 1746-1751
    • Le Jeune, F.1    Drapier, D.2    Bourguignon, A.3
  • 98
    • 0036904309 scopus 로고    scopus 로고
    • The apathy inventory: assessment of apathy and awareness in Alzheimer's disease, Parkinson's disease and mild cognitive impairment
    • Robert PH, Clairet S, Benoit M, et al. The apathy inventory: assessment of apathy and awareness in Alzheimer's disease, Parkinson's disease and mild cognitive impairment. Int J Geriatr Psychiatry 2002, 17:1099-1105.
    • (2002) Int J Geriatr Psychiatry , vol.17 , pp. 1099-1105
    • Robert, P.H.1    Clairet, S.2    Benoit, M.3
  • 99
    • 0031882299 scopus 로고    scopus 로고
    • Subthalamic nucleus or internal pallidal stimulation in young onset Parkinson's disease
    • Krack P, Pollak P, Limousin P, et al. Subthalamic nucleus or internal pallidal stimulation in young onset Parkinson's disease. Brain 1998, 121:451-457.
    • (1998) Brain , vol.121 , pp. 451-457
    • Krack, P.1    Pollak, P.2    Limousin, P.3
  • 100
    • 33745212232 scopus 로고    scopus 로고
    • Does subthalamic nucleus stimulation induce apathy in Parkinson's disease?
    • Drapier D, Drapier S, Sauleau P, et al. Does subthalamic nucleus stimulation induce apathy in Parkinson's disease?. J Neurol 2006, 253:1083-1091.
    • (2006) J Neurol , vol.253 , pp. 1083-1091
    • Drapier, D.1    Drapier, S.2    Sauleau, P.3
  • 101
    • 0242658923 scopus 로고    scopus 로고
    • Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease
    • Krack P, Batir A, Van Blercom N, et al. Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease. N Engl J Med 2003, 349:1925-1934.
    • (2003) N Engl J Med , vol.349 , pp. 1925-1934
    • Krack, P.1    Batir, A.2    Van Blercom, N.3
  • 102
    • 84885154895 scopus 로고    scopus 로고
    • Postoperative management of deep brain stimulation in Parkinson's disease
    • Castrioto A, Volkmann J, Krack P Postoperative management of deep brain stimulation in Parkinson's disease. Handb Clin Neurol 2013, 116:129-146.
    • (2013) Handb Clin Neurol , vol.116 , pp. 129-146
    • Castrioto, A.1    Volkmann, J.2    Krack, P.3
  • 103
    • 84873675072 scopus 로고    scopus 로고
    • Neurostimulation for Parkinson's disease with early motor complications
    • the EARLYSTIM Study Group
    • Schuepbach WM, Rau J, Knudsen K, et al. Neurostimulation for Parkinson's disease with early motor complications. N Engl J Med 2013, 368:610-622. the EARLYSTIM Study Group.
    • (2013) N Engl J Med , vol.368 , pp. 610-622
    • Schuepbach, W.M.1    Rau, J.2    Knudsen, K.3
  • 104
    • 20444386949 scopus 로고    scopus 로고
    • Does bilateral stimulation of the subthalamic nucleus aggravate apathy in Parkinson's disease?
    • Czernecki V, Pillon B, Houeto JL, et al. Does bilateral stimulation of the subthalamic nucleus aggravate apathy in Parkinson's disease?. J Neurol Neurosurg Psychiatry 2005, 76:775-779.
    • (2005) J Neurol Neurosurg Psychiatry , vol.76 , pp. 775-779
    • Czernecki, V.1    Pillon, B.2    Houeto, J.L.3
  • 105
    • 0037809611 scopus 로고    scopus 로고
    • Acute psychotropic effects of bilateral subthalamic nucleus stimulation and levodopa in Parkinson's disease
    • Funkiewiez A, Ardouin C, Krack P, et al. Acute psychotropic effects of bilateral subthalamic nucleus stimulation and levodopa in Parkinson's disease. Mov Disord 2003, 18:524-530.
    • (2003) Mov Disord , vol.18 , pp. 524-530
    • Funkiewiez, A.1    Ardouin, C.2    Krack, P.3
  • 106
    • 0037337202 scopus 로고    scopus 로고
    • Deep brain stimulation of the subthalamic nucleus enhances emotional processing in Parkinson disease
    • Schneider F, Habel U, Volkmann J, et al. Deep brain stimulation of the subthalamic nucleus enhances emotional processing in Parkinson disease. Arch Gen Psychiatry 2003, 60:296-302.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 296-302
    • Schneider, F.1    Habel, U.2    Volkmann, J.3
  • 107
    • 84871227475 scopus 로고    scopus 로고
    • Psychostimulant effect of levodopa: reversing sensitisation is possible
    • Castrioto A, Kistner A, Klinger H, et al. Psychostimulant effect of levodopa: reversing sensitisation is possible. J Neurol Neurosurg Psychiatry 2013, 84:18-22.
    • (2013) J Neurol Neurosurg Psychiatry , vol.84 , pp. 18-22
    • Castrioto, A.1    Kistner, A.2    Klinger, H.3
  • 108
    • 49249084391 scopus 로고    scopus 로고
    • Apathy following subthalamic stimulation in Parkinson disease: a dopamine responsive symptom
    • Czernecki V, Schupbach M, Yaici S, et al. Apathy following subthalamic stimulation in Parkinson disease: a dopamine responsive symptom. Mov Disord 2008, 23:964-969.
    • (2008) Mov Disord , vol.23 , pp. 964-969
    • Czernecki, V.1    Schupbach, M.2    Yaici, S.3
  • 109
    • 84877296484 scopus 로고    scopus 로고
    • Parkinsonian apathy responds to dopaminergic stimulation of D2/D3 receptors with piribedil
    • Thobois S, Lhommée E, Klinger H, et al. Parkinsonian apathy responds to dopaminergic stimulation of D2/D3 receptors with piribedil. Brain 2013, 136:1568-1577.
    • (2013) Brain , vol.136 , pp. 1568-1577
    • Thobois, S.1    Lhommée, E.2    Klinger, H.3
  • 110
    • 0033955756 scopus 로고    scopus 로고
    • Evidence for impaired presynaptic dopamine function in parkinsonian patients with motor fluctuations
    • de la Fuente-Fernández R, Pal PK, Vingerhoets FJ, et al. Evidence for impaired presynaptic dopamine function in parkinsonian patients with motor fluctuations. J Neural Transm 2000, 107:49-57.
    • (2000) J Neural Transm , vol.107 , pp. 49-57
    • de la Fuente-Fernández, R.1    Pal, P.K.2    Vingerhoets, F.J.3
  • 111
    • 33750440804 scopus 로고    scopus 로고
    • Cognitive decline correlates with neuropathological stage in Parkinson's disease
    • Braak H, Rüb U, Del Tredici K Cognitive decline correlates with neuropathological stage in Parkinson's disease. J Neurol Sci 2006, 248:255-258.
    • (2006) J Neurol Sci , vol.248 , pp. 255-258
    • Braak, H.1    Rüb, U.2    Del Tredici, K.3
  • 112
    • 17644426053 scopus 로고    scopus 로고
    • Cognitive status correlates with neuropathologic stage in Parkinson disease
    • Braak H, Rüb U, Jansen Steur EN, Del Tredici K, de Vos RA Cognitive status correlates with neuropathologic stage in Parkinson disease. Neurology 2005, 64:1404-1410.
    • (2005) Neurology , vol.64 , pp. 1404-1410
    • Braak, H.1    Rüb, U.2    Jansen Steur, E.N.3    Del Tredici, K.4    de Vos, R.A.5
  • 113
    • 14944354884 scopus 로고    scopus 로고
    • Sydney Multicenter Study of Parkinson's disease: non-L-dopa-responsive problems dominate at 15 years
    • Hely MA, Morris JG, Reid WG, Trafficante R Sydney Multicenter Study of Parkinson's disease: non-L-dopa-responsive problems dominate at 15 years. Mov Disord 2005, 20:190-199.
    • (2005) Mov Disord , vol.20 , pp. 190-199
    • Hely, M.A.1    Morris, J.G.2    Reid, W.G.3    Trafficante, R.4
  • 114
    • 41149173996 scopus 로고    scopus 로고
    • The Sydney multicenter study of Parkinson's disease: the inevitability of dementia at 20 years
    • Hely MA, Reid WG, Adena MA, Halliday GM, Morris JG The Sydney multicenter study of Parkinson's disease: the inevitability of dementia at 20 years. Mov Disord 2008, 23:837-844.
    • (2008) Mov Disord , vol.23 , pp. 837-844
    • Hely, M.A.1    Reid, W.G.2    Adena, M.A.3    Halliday, G.M.4    Morris, J.G.5
  • 115
    • 0032854678 scopus 로고    scopus 로고
    • Bilateral subthalamic or pallidal stimulation for Parkinson's disease affects neither memory nor executive functions: a consecutive series of 62 patients
    • Ardouin C, Pillon B, Peiffer E, et al. Bilateral subthalamic or pallidal stimulation for Parkinson's disease affects neither memory nor executive functions: a consecutive series of 62 patients. Ann Neurol 1999, 46:217-223.
    • (1999) Ann Neurol , vol.46 , pp. 217-223
    • Ardouin, C.1    Pillon, B.2    Peiffer, E.3
  • 116
    • 33744998323 scopus 로고    scopus 로고
    • Cognitive sequelae of subthalamic nucleus deep brain stimulation in Parkinson's disease: a meta-analysis
    • Parsons TD, Rogers SA, Braaten AJ, Woods SP, Tröster AI Cognitive sequelae of subthalamic nucleus deep brain stimulation in Parkinson's disease: a meta-analysis. Lancet Neurol 2006, 5:578-588.
    • (2006) Lancet Neurol , vol.5 , pp. 578-588
    • Parsons, T.D.1    Rogers, S.A.2    Braaten, A.J.3    Woods, S.P.4    Tröster, A.I.5
  • 117
    • 84879907555 scopus 로고    scopus 로고
    • Relation of lead trajectory and electrode position to neuropsychological outcomes of subthalamic neurostimulation in Parkinson's disease: results from a randomized trial
    • Witt K, Granert O, Daniels C, et al. Relation of lead trajectory and electrode position to neuropsychological outcomes of subthalamic neurostimulation in Parkinson's disease: results from a randomized trial. Brain 2013, 136:2109-2119.
    • (2013) Brain , vol.136 , pp. 2109-2119
    • Witt, K.1    Granert, O.2    Daniels, C.3
  • 118
    • 84871815778 scopus 로고    scopus 로고
    • Long-term outcomes of surgical therapies for Parkinson's disease
    • Rodriguez-Oroz MC, Moro E, Krack P Long-term outcomes of surgical therapies for Parkinson's disease. Mov Disord 2012, 27:1718-1728.
    • (2012) Mov Disord , vol.27 , pp. 1718-1728
    • Rodriguez-Oroz, M.C.1    Moro, E.2    Krack, P.3
  • 119
    • 79953873164 scopus 로고    scopus 로고
    • Pramipexole modulates the neural network of reward anticipation
    • Ye Z, Hammer A, Camara E, Münte TF Pramipexole modulates the neural network of reward anticipation. Hum Brain Mapp 2011, 32:800-811.
    • (2011) Hum Brain Mapp , vol.32 , pp. 800-811
    • Ye, Z.1    Hammer, A.2    Camara, E.3    Münte, T.F.4
  • 120
    • 67349195803 scopus 로고    scopus 로고
    • Changes in artistic style and behaviour in Parkinson's disease: dopamine and creativity
    • Kulisevsky J, Pagonabarraga J, Martinez-Corral M Changes in artistic style and behaviour in Parkinson's disease: dopamine and creativity. J Neurol 2009, 256:816-819.
    • (2009) J Neurol , vol.256 , pp. 816-819
    • Kulisevsky, J.1    Pagonabarraga, J.2    Martinez-Corral, M.3
  • 121
    • 84901062916 scopus 로고    scopus 로고
    • Dopamine and the biology of creativity: lessons from Parkinson's disease
    • Lhommée E, Batir A, Quesada JL, et al. Dopamine and the biology of creativity: lessons from Parkinson's disease. Front Neurol 2014, 5:55.
    • (2014) Front Neurol , vol.5 , pp. 55
    • Lhommée, E.1    Batir, A.2    Quesada, J.L.3
  • 122
    • 84865300674 scopus 로고    scopus 로고
    • Extrastriatal dopaminergic abnormalities of DA homeostasis in Parkinson's patients with medication-induced pathological gambling: a [11C] FLB-457 and PET study
    • Ray NJ, Miyasaki JM, Zurowski M, et al. Extrastriatal dopaminergic abnormalities of DA homeostasis in Parkinson's patients with medication-induced pathological gambling: a [11C] FLB-457 and PET study. Neurobiol Dis 2012, 48:519-525.
    • (2012) Neurobiol Dis , vol.48 , pp. 519-525
    • Ray, N.J.1    Miyasaki, J.M.2    Zurowski, M.3
  • 123
    • 33646897697 scopus 로고    scopus 로고
    • The Lille apathy rating scale (LARS), a new instrument for detecting and quantifying apathy: validation in Parkinson's disease
    • Sockeel P, Dujardin K, Devos D, Denève C, Destée A, Defebvre L The Lille apathy rating scale (LARS), a new instrument for detecting and quantifying apathy: validation in Parkinson's disease. J Neurol Neurosurg Psychiatry 2006, 77:579-584.
    • (2006) J Neurol Neurosurg Psychiatry , vol.77 , pp. 579-584
    • Sockeel, P.1    Dujardin, K.2    Devos, D.3    Denève, C.4    Destée, A.5    Defebvre, L.6
  • 125
    • 66149121846 scopus 로고    scopus 로고
    • Cognitive declines one year after unilateral deep brain stimulation surgery in Parkinson's disease: a controlled study using reliable change
    • Zahodne LB, Okun MS, Foote KD, et al. Cognitive declines one year after unilateral deep brain stimulation surgery in Parkinson's disease: a controlled study using reliable change. Clin Neuropsychol 2009, 23:385-405.
    • (2009) Clin Neuropsychol , vol.23 , pp. 385-405
    • Zahodne, L.B.1    Okun, M.S.2    Foote, K.D.3
  • 126
    • 67651177762 scopus 로고    scopus 로고
    • The syndromal validity and nosological position of apathy in Parkinson's disease
    • Starkstein SE, Merello M, Jorge R, Brockman S, Bruce D, Power B The syndromal validity and nosological position of apathy in Parkinson's disease. Mov Disord 2009, 24:1211-1216.
    • (2009) Mov Disord , vol.24 , pp. 1211-1216
    • Starkstein, S.E.1    Merello, M.2    Jorge, R.3    Brockman, S.4    Bruce, D.5    Power, B.6
  • 128
    • 60849137194 scopus 로고    scopus 로고
    • Proposed diagnostic criteria for apathy in Alzheimer's disease and other neuropsychiatric disorders
    • Robert P, Onyike CU, Leentjens AF, et al. Proposed diagnostic criteria for apathy in Alzheimer's disease and other neuropsychiatric disorders. Eur Psychiatry 2009, 24:98-104.
    • (2009) Eur Psychiatry , vol.24 , pp. 98-104
    • Robert, P.1    Onyike, C.U.2    Leentjens, A.F.3
  • 129
    • 79953276342 scopus 로고    scopus 로고
    • The impact of non-motor symptoms on health-related quality of life of patients with Parkinson's disease
    • Martinez-Martin P, Rodriguez-Blazquez C, Kurtis MM, Chaudhuri KR The impact of non-motor symptoms on health-related quality of life of patients with Parkinson's disease. Mov Disord 2011, 26:399-406.
    • (2011) Mov Disord , vol.26 , pp. 399-406
    • Martinez-Martin, P.1    Rodriguez-Blazquez, C.2    Kurtis, M.M.3    Chaudhuri, K.R.4
  • 130
    • 84899929969 scopus 로고    scopus 로고
    • Rivastigmine in apathetic but dementia and depression-free patients with Parkinson's disease: a double-blind, placebo-controlled, randomised clinical trial
    • Devos D, Moreau C, Maltête D, et al. Rivastigmine in apathetic but dementia and depression-free patients with Parkinson's disease: a double-blind, placebo-controlled, randomised clinical trial. J Neurol Neurosurg Psychiatry 2014, 85:668-674.
    • (2014) J Neurol Neurosurg Psychiatry , vol.85 , pp. 668-674
    • Devos, D.1    Moreau, C.2    Maltête, D.3
  • 131
    • 60349118998 scopus 로고    scopus 로고
    • The effect of pramipexole on mood and motivational symptoms in Parkinson's disease: a meta-analysis of placebo-controlled studies
    • Leentjens AF, Koester J, Fruh B, Shephard DT, Barone P, Houben JJ The effect of pramipexole on mood and motivational symptoms in Parkinson's disease: a meta-analysis of placebo-controlled studies. Clin Ther 2009, 31:89-98.
    • (2009) Clin Ther , vol.31 , pp. 89-98
    • Leentjens, A.F.1    Koester, J.2    Fruh, B.3    Shephard, D.T.4    Barone, P.5    Houben, J.J.6
  • 132
    • 0036754180 scopus 로고    scopus 로고
    • Methylphenidate treats apathy in Parkinson's disease
    • Chatterjee A, Fahn S Methylphenidate treats apathy in Parkinson's disease. J Neuropsychiatry Clin Neurosci 2002, 14:461-462.
    • (2002) J Neuropsychiatry Clin Neurosci , vol.14 , pp. 461-462
    • Chatterjee, A.1    Fahn, S.2
  • 133
    • 84862326058 scopus 로고    scopus 로고
    • Methylphenidate for gait hypokinesia and freezing in patients with Parkinson's disease undergoing subthalamic stimulation: a multicentre, parallel, randomised, placebo-controlled trial
    • the Parkgait-II study group
    • Moreau C, Delval A, Defebvre L, et al. Methylphenidate for gait hypokinesia and freezing in patients with Parkinson's disease undergoing subthalamic stimulation: a multicentre, parallel, randomised, placebo-controlled trial. Lancet Neurol 2012, 11:589-596. the Parkgait-II study group.
    • (2012) Lancet Neurol , vol.11 , pp. 589-596
    • Moreau, C.1    Delval, A.2    Defebvre, L.3
  • 134
    • 51449084071 scopus 로고    scopus 로고
    • Methylphenidate for the treatment of apathy in Alzheimer disease: prediction of response using dextroamphetamine challenge
    • Herrmann N, Rothenburg LS, Black SE, et al. Methylphenidate for the treatment of apathy in Alzheimer disease: prediction of response using dextroamphetamine challenge. J Clin Psychopharmacol 2008, 28:296-301.
    • (2008) J Clin Psychopharmacol , vol.28 , pp. 296-301
    • Herrmann, N.1    Rothenburg, L.S.2    Black, S.E.3
  • 135
    • 84892157086 scopus 로고    scopus 로고
    • Effect of methylphenidate on attention in apathetic AD patients in a randomized, placebo-controlled trial
    • LanctÔt KL, Chau SA, Herrmann N, et al. Effect of methylphenidate on attention in apathetic AD patients in a randomized, placebo-controlled trial. Int Psychogeriatr 2014, 26:239-246.
    • (2014) Int Psychogeriatr , vol.26 , pp. 239-246
    • LanctÔt, K.L.1    Chau, S.A.2    Herrmann, N.3
  • 136
    • 84883176211 scopus 로고    scopus 로고
    • Safety and efficacy of methylphenidate for apathy in Alzheimer's disease: a randomized, placebo-controlled trial
    • the ADMET Investigators
    • Rosenberg PB, LanctÔt KL, Drye LT, et al. Safety and efficacy of methylphenidate for apathy in Alzheimer's disease: a randomized, placebo-controlled trial. J Clin Psychiatry 2013, 74:810-816. the ADMET Investigators.
    • (2013) J Clin Psychiatry , vol.74 , pp. 810-816
    • Rosenberg, P.B.1    LanctÔt, K.L.2    Drye, L.T.3
  • 137
    • 0004426405 scopus 로고
    • Methyl phenidate in parkinsonism
    • Halliday AM, Nathan PW Methyl phenidate in parkinsonism. BMJ 1961, 1:1652-1655.
    • (1961) BMJ , vol.1 , pp. 1652-1655
    • Halliday, A.M.1    Nathan, P.W.2
  • 138
    • 0024319401 scopus 로고
    • Major depression in Parkinson's disease and the mood response to intravenous methylphenidate: possible role of the "hedonic" dopamine synapse
    • Cantello R, Aguggia M, Gilli M, et al. Major depression in Parkinson's disease and the mood response to intravenous methylphenidate: possible role of the "hedonic" dopamine synapse. J Neurol Neurosurg Psychiatry 1989, 52:724-731.
    • (1989) J Neurol Neurosurg Psychiatry , vol.52 , pp. 724-731
    • Cantello, R.1    Aguggia, M.2    Gilli, M.3
  • 139
    • 0036266051 scopus 로고    scopus 로고
    • Behavioural disorders, Parkinson's disease and subthalamic stimulation
    • Houeto JL, Mesnage V, Mallet L, et al. Behavioural disorders, Parkinson's disease and subthalamic stimulation. J Neurol Neurosurg Psychiatry 2002, 72:701-707.
    • (2002) J Neurol Neurosurg Psychiatry , vol.72 , pp. 701-707
    • Houeto, J.L.1    Mesnage, V.2    Mallet, L.3
  • 140
    • 84867512470 scopus 로고    scopus 로고
    • Are selective serotonin reuptake inhibitors associated with greater apathy in Parkinson's disease?
    • Zahodne LB, Bernal-Pacheco O, Bowers D, et al. Are selective serotonin reuptake inhibitors associated with greater apathy in Parkinson's disease?. J Neuropsychiatry Clin Neurosci 2012, 24:326-330.
    • (2012) J Neuropsychiatry Clin Neurosci , vol.24 , pp. 326-330
    • Zahodne, L.B.1    Bernal-Pacheco, O.2    Bowers, D.3
  • 141
    • 33947099919 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitor use associates with apathy among depressed elderly: a case-control study
    • Wongpakaran N, van Reekum R, Wongpakaran T, Clarke D Selective serotonin reuptake inhibitor use associates with apathy among depressed elderly: a case-control study. Ann Gen Psychiatry 2007, 6:7.
    • (2007) Ann Gen Psychiatry , vol.6 , pp. 7
    • Wongpakaran, N.1    van Reekum, R.2    Wongpakaran, T.3    Clarke, D.4
  • 145
    • 0035526256 scopus 로고    scopus 로고
    • Neuropsychiatric assessment of Gilles de la Tourette patients: comparative study with other hyperkinetic and hypokinetic movement disorders
    • Kulisevsky J, Litvan I, Berthier ML, Pascual-Sedano B, Paulsen JS, Cummings JL Neuropsychiatric assessment of Gilles de la Tourette patients: comparative study with other hyperkinetic and hypokinetic movement disorders. Mov Disord 2001, 16:1098-1104.
    • (2001) Mov Disord , vol.16 , pp. 1098-1104
    • Kulisevsky, J.1    Litvan, I.2    Berthier, M.L.3    Pascual-Sedano, B.4    Paulsen, J.S.5    Cummings, J.L.6
  • 148
    • 84863399752 scopus 로고    scopus 로고
    • Longitudinal evaluation of neuropsychiatric symptoms in Huntington's disease
    • Thompson JC, Harris J, Sollom AC, et al. Longitudinal evaluation of neuropsychiatric symptoms in Huntington's disease. J Neuropsychiatry Clin Neurosci 2012, 24:53-60.
    • (2012) J Neuropsychiatry Clin Neurosci , vol.24 , pp. 53-60
    • Thompson, J.C.1    Harris, J.2    Sollom, A.C.3
  • 149
  • 150
    • 84879032355 scopus 로고    scopus 로고
    • Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: analysis of 36-month observational data
    • the TRACK-HD Investigators
    • Tabrizi SJ, Scahill RI, Owen G, et al. Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: analysis of 36-month observational data. Lancet Neurol 2013, 12:637-649. the TRACK-HD Investigators.
    • (2013) Lancet Neurol , vol.12 , pp. 637-649
    • Tabrizi, S.J.1    Scahill, R.I.2    Owen, G.3
  • 151
    • 0034990134 scopus 로고    scopus 로고
    • Behaviour in frontotemporal dementia, Alzheimer's disease and vascular dementia
    • Bathgate D, Snowden JS, Varma A, Blackshaw A, Neary D Behaviour in frontotemporal dementia, Alzheimer's disease and vascular dementia. Acta Neurol Scand 2001, 103:367-378.
    • (2001) Acta Neurol Scand , vol.103 , pp. 367-378
    • Bathgate, D.1    Snowden, J.S.2    Varma, A.3    Blackshaw, A.4    Neary, D.5
  • 152
    • 0029854681 scopus 로고    scopus 로고
    • Neuropsychiatric aspects of progressive supranuclear palsy
    • Litvan I, Mega MS, Cummings JL, Fairbanks L Neuropsychiatric aspects of progressive supranuclear palsy. Neurology 1996, 47:1184-1189.
    • (1996) Neurology , vol.47 , pp. 1184-1189
    • Litvan, I.1    Mega, M.S.2    Cummings, J.L.3    Fairbanks, L.4
  • 154
    • 84879949247 scopus 로고    scopus 로고
    • Subthalamic nucleus stimulation and compulsive use of dopaminergic medication in Parkinson's disease
    • Eusebio A, Witjas T, Cohen J, et al. Subthalamic nucleus stimulation and compulsive use of dopaminergic medication in Parkinson's disease. J Neurol Neurosurg Psychiatry 2013, 84:868-874.
    • (2013) J Neurol Neurosurg Psychiatry , vol.84 , pp. 868-874
    • Eusebio, A.1    Witjas, T.2    Cohen, J.3
  • 155
    • 77949273396 scopus 로고    scopus 로고
    • Apathy in drug-naïve patients with incident Parkinson's disease: the Norwegian ParkWest study
    • Pedersen KF, Alves G, Brønnick K, Aarsland D, Tysnes OB, Larsen JP Apathy in drug-naïve patients with incident Parkinson's disease: the Norwegian ParkWest study. J Neurol 2010, 257:217-223.
    • (2010) J Neurol , vol.257 , pp. 217-223
    • Pedersen, K.F.1    Alves, G.2    Brønnick, K.3    Aarsland, D.4    Tysnes, O.B.5    Larsen, J.P.6


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