Mental and behavioral disturbances in dementia: Findings from the cache county study on memory in aging

American Journal of Psychiatry

Volumn 157, Issue 5, 2000, Pages 708-714

  Lyketsos, Constantine G ^a   Steinberg, Martin ^b   Tschanz, JoAnn T ^b   Norton, Maria C ^b   Steffens, David C ^b   Breitner, John C S ^b  

^a JOHNS HOPKINS HOSPITAL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AGED; AGGRESSION; AGING; AGITATION; ALZHEIMER DISEASE; APATHY; ARTICLE; BEHAVIOR DISORDER; CONTROLLED STUDY; DELUSION; DEMENTIA; DEPRESSION; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MASS SCREENING; MEMORY; MENTAL DISEASE; MULTIINFARCT DEMENTIA; NEUROPSYCHOLOGICAL TEST; PRIORITY JOURNAL; UNITED STATES;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; COMORBIDITY; DELUSIONS; DEMENTIA; DEMENTIA, VASCULAR; DEPRESSIVE DISORDER; FEMALE; GERIATRIC ASSESSMENT; HUMANS; MALE; MENTAL DISORDERS; PREVALENCE; PSYCHIATRIC STATUS RATING SCALES; SAMPLING STUDIES; SEVERITY OF ILLNESS INDEX; UTAH;

EID: 0034016372     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/appi.ajp.157.5.708     Document Type: Article

References (34)

1. Rabins PV, Lyketsos CG, Steele CD: Practical Dementia Care. New York, Oxford University Press, 1999
2. Lyketsos CG, Steele C, Steinberg M: Behavioral disturbances in dementia, in Reichel's Care of the Elderly: Clinical Aspects of Aging, 5th ed. Edited by Gallo JJ, Busby-Whitehead J, Rabins PV, Silliman RA, Murphy JB, Reichel W, Baltimore, Williams & Wilkins, 1999, pp 214-228
3. Mega MS, Cummings JL, Fiorello T, Gornbein J: The spectrum of behavioral changes in Alzheimer's disease. Neurology 1996; 46:130-135
4. Finkel S (ed): Behavioral Disturbance in Dementia. Int Psychogeriatrics 1996; 8(suppl 3)
5. Groves WC, Brandt J, Steinberg M, Warren A, Rosenblatt A, Baker AS, Lyketsos CG: Vascular dementia and Alzheimer disease: is there are difference? a comparison of symptoms by disease severity J Neuropsychiatry Clin Neurosci (in press)
6. Payne JL, Lyketsos CG, Baker L, Warren A, Steele C, Brandt J, Steinberg M, Kopunek S, Baker A: The relationship of cognitive and functional impairment to depressive features in Alzheimer's disease and other dementias. J Neuropsychiatry Clin Neurosci 1998; 10:440-447
7. Molsa PK, Martilla RJ, Rinne UK: Long-term survival and predictors of mortality in Alzheimer's disease and multi-infarct dementia. Acta Neurol Scand 1995; 91:159-164
8. Sultzer DL, Levin HS, Mahler ME, High WM, Cummings JL: A comparison of psychiatric symptoms in vascular dementia and Alzheimer's disease. Am J Psychiatry 1993; 150:1806-1812
9. Drevets WC, Rubin EH: Psychotic symptoms and the longitudinal course of senile dementia of the Alzheimer type. Biol Psychiatry 1989; 25:39-48
10. Rosen J, Zubenko GS: Emergence of psychosis and depression in the longitudinal evaluation of Alzheimer's disease. Biol Psychiatry 1991; 29:224-232
11. Rao V, Lyketsos CG: Delusions in Alzheimer's disease: a review. J Neuropsychiatry Clin Neurosci 1998; 10:373-382
12. Burns A, Jacoby R, Levy R: Psychiatric phenomena in Alzheimer's disease, I: disorders of thought content. Br J Psychiatry 1990; 157:72-76
13. Burns A, Jacoby R, Levy R: Psychiatric phenomena in Alzheimer's disease, II: disorders of perception. Br J Psychiatry 1990; 157:76-81
14. Burns A, Jacoby R, Levy R: Psychiatric phenomena in Alzheimer's disease, III: disorders of mood. Br J Psychiatry 1990; 157:81-86
15. Burns A, Jacoby R, Levy R: Psychiatric phenomena in Alzheimer's disease, IV: disorders of behavior. Br J Psychiatry 1990; 157:86-94
16. Cummings JL, Mega M, Gray K, Rosenberg-Thompson S, Carusi DA, Gornbein J: The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia. Neurology 1994; 44:2308-2314
17. Breitner JCS, Wyse BW, Anthony JC, Welsh-Bohmer KA, Steffens DC, Norton M, Tschanz JT, Plassman BL, Meyer MR, Skoog I, Khachaturian A: APOE-epsilon 4 count predicts age when prevalence of Alzheimer's disease increases - then declines: the Cache County Study. Neurology 1999; 52:321-331
18. Teng EL, Chui HC: The Modified Mini-Mental State (3MS) examination. J Clin Psychiatry 1987; 48:314-318
19. Jorm AF: A short form of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE): development and cross-validation. Psychol Med 1994; 24:145-153
20. Silverman JM, Breitner JCS, Mohs RC, Davis KL: Reliability of the family history method in genetic studies of Alzheimer's disease and related dementias. Am J Psychiatry 1986; 143: 1279-1282
21. Morris J: Clinical Dementia Rating Scale. St Louis, Washington University, 1994
22. Lyketsos CG, Steinberg M: Cognitive disorders, non-cognitive measures, in Handbook of Psychiatric Measures. Washington, DC, American Psychiatric Association (in press)
23. Alexopoulos GS, Meyers BS, Young RC, Campbell S, Silbersweig D, Charlson M: Vascular depression hypothesis. Arch Gen Psychiatry 1997; 54:915-922
24. Zubenko GS, Moossy J, Martinez AJ, Rao G, Ciaassen D, Rosen J, Kopp U: Neuropathologic and neurochemical correlates of psychosis in primary dementia. Arch Neural 1991; 48:619-624
25. Starkstein SL, Vazquez S, Petracca G: A SPECT study of delusions in Alzheimer's disease. Neurology 1994; 44:2055-2059
26. Nyth AL, Gottfries CG: The clinical efficacy of citalopram in treatment of emotional disturbances of dementia subjects. Br J Psychiatry 1990; 157:894-901
27. Reifler BV, Teri L, Raskind M, Veith R, Barnes R, White E, McLean P: Double-blind trial of imipramine in Alzheimer's disease patients with and without depression. Am J Psychiatry 1989; 146:45-49
28. Petracca G, Teson A, Chemerinski L, Leiguarda R, Starkstein SE: A double-blind placebo-controlled study of clomipramine in depressed patients with Alzheimer's disease. J Neuropsychiatry Clin Neurosci 1996; 8:270-275
29. Katz IR, Jeste DV, Mintzer JE, Clyde C, NapolitanoJ, Brecher M (Risperidone Study Group): Comparison of risperidone and placebo for psychosis and behavioral disturbances associated with dementia: a randomized, double-blind trial. J Clin Psychiatry 1999; 60:107-115
30. Street J, Clark WS, Cannon KS, Miran S, Sanger T, Tollefson GD: Olanzapine in the treatment of psychosis and behavioral disturbances associated with Alzheimer's disease, in 1999 Annual Meeting New Research Program and Abstracts. Washington, DC, American Psychiatric Association, 1999, pp 225-226
31. Tariot PN, Erb R, Podgorski CA, Cox C, Patel S, Jakimovich L, Irvine C: Efficacy and tolerability of carbamazepine for agitation and aggression in dementia. Am J Psychiatry 1998; 155: 54-61
32. Morris JC, Cyrus PA, Orazem J, Mas J, Bieber F, Ruzicka BB, Gulanski B: Metrifonate benefits cognitive, behavioral, and global function in patients with Alzheimer's disease. Neurology 1998; 50:1222-1230
33. Lyketsos CG, Veiel LL, Sheppard JME, Baker A, Steele CS: A randomized, controlled trial of bright light therapy for agitated behaviors in dementia patients residing in long-term care. Int J Geriatr Psychiatry 1999; 14:520-525
34. Teri L: Behavioral treatment of depression in patients with dementia. Alzheimer Dis Assoc Disord 1994; 8(suppl 3):66-74