메뉴 건너뛰기




Volumn 136, Issue 5, 2013, Pages 1568-1577

Parkinsonian apathy responds to dopaminergic stimulation of D2/D3 receptors with piribedil

Author keywords

apathy; dopamine agonist; Parkinson; piribedil; subthalamic nucleus

Indexed keywords

DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; PIRIBEDIL; PLACEBO;

EID: 84877296484     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awt067     Document Type: Article
Times cited : (218)

References (46)
  • 1
    • 72849115874 scopus 로고    scopus 로고
    • Neuropsychiatric symptoms in Parkinson's disease
    • Aarsland D, Marsh L, Schrag A. Neuropsychiatric symptoms in Parkinson's disease. Mov Disord 2009; 24: 2175-86.
    • (2009) Mov Disord , vol.24 , pp. 2175-2186
    • Aarsland, D.1    Marsh, L.2    Schrag, A.3
  • 3
    • 77952545893 scopus 로고    scopus 로고
    • Pramipexole for the treatment of depressive symptoms in patients with Parkinson's disease: A randomised, double-blind, placebo-controlled trial
    • Barone P, Poewe W, Albrecht S, Debieuvre C, Massey D, Rascol O, et al. Pramipexole for the treatment of depressive symptoms in patients with Parkinson's disease: a randomised, double-blind, placebo-controlled trial. Lancet Neurol 2010; 9: 573-80.
    • (2010) Lancet Neurol , vol.9 , pp. 573-580
    • Barone, P.1    Poewe, W.2    Albrecht, S.3    Debieuvre, C.4    Massey, D.5    Rascol, O.6
  • 5
    • 0024245652 scopus 로고
    • An inventory for measuring clinical anxiety: Psychometric properties
    • Beck AT, Epstein N, Brown G, Steer RA. An inventory for measuring clinical anxiety: psychometric properties. J Consult Clin Psychol 1988; 56: 893-7.
    • (1988) J Consult Clin Psychol , vol.56 , pp. 893-897
    • Beck, A.T.1    Epstein, N.2    Brown, G.3    Steer, R.A.4
  • 6
    • 84856230910 scopus 로고    scopus 로고
    • Impact of apathy on health-related quality of life in recently diagnosed Parkinson's diseae: The ANIMO study
    • Benito-Leon J, Cubo E, Coronell C. Impact of apathy on health-related quality of life in recently diagnosed Parkinson's diseae: the ANIMO study. Mov Disord 2012; 27: 211-8.
    • (2012) Mov Disord , vol.27 , pp. 211-218
    • Benito-Leon, J.1    Cubo, E.2    Coronell, C.3
  • 7
    • 70349922298 scopus 로고    scopus 로고
    • Reward-learning and the novelty-seeking personality: A betweenand within-subjects study of the effects of dopamine agonists on young Parkinson's patients
    • Bó di N, Ké ri S, Nagy H, Moustafa A, Myers CE, Daw N, et al. Reward-learning and the novelty-seeking personality: a betweenand within-subjects study of the effects of dopamine agonists on young Parkinson's patients. Brain 2009; 132 (Pt 9): 2385-95.
    • (2009) Brain , vol.132 , Issue.PART 9 , pp. 2385-2395
    • Bó Di, N.1    Ké Ri, S.2    Nagy, H.3    Moustafa, A.4    Myers, C.E.5    Daw, N.6
  • 8
    • 33646238464 scopus 로고    scopus 로고
    • The Parkinson-Control study: A 1-year randomized, doubleblind trial comparing piribedil (150 mg/day) with bromocriptine (25 mg/day) in early combination with levodopa in Parkinson's disease
    • Castro-Caldas A, Delwaide P, Jost W, Merello M, Williams A, Lamberti P, et al. The Parkinson-Control study: a 1-year randomized, doubleblind trial comparing piribedil (150 mg/day) with bromocriptine (25 mg/day) in early combination with levodopa in Parkinson's disease. Mov Disord 2006; 21: 500-9.
    • (2006) Mov Disord , vol.21 , pp. 500-509
    • Castro-Caldas, A.1    Delwaide, P.2    Jost, W.3    Merello, M.4    Williams, A.5    Lamberti, P.6
  • 9
    • 64349083816 scopus 로고    scopus 로고
    • Non-motor symptoms of Parkinson's disease: Dopaminergic pathophysiology and treatment
    • Chaudhuri KR, Schapira AH. Non-motor symptoms of Parkinson's disease: dopaminergic pathophysiology and treatment. Lancet Neurol 2009; 8: 464-74.
    • (2009) Lancet Neurol , vol.8 , pp. 464-474
    • Chaudhuri, K.R.1    Schapira, A.H.2
  • 10
    • 49249084391 scopus 로고    scopus 로고
    • Apathy following subthalamic stimulation in Parkinson disease: A dopamine responsive symptom
    • Czernecki V, Schü pbach M, Yaici S, Lé vy R, Bardinet E, Yelnik J, et al. Apathy following subthalamic stimulation in Parkinson disease: a dopamine responsive symptom. Mov Disord 2008; 23: 964-9.
    • (2008) Mov Disord , vol.23 , pp. 964-969
    • Czernecki, V.1    Schü Pbach, M.2    Yaici, S.3    Lé Vy, R.4    Bardinet, E.5    Yelnik, J.6
  • 12
    • 84867539266 scopus 로고    scopus 로고
    • Apathy in Parkinson's disease: What are the underlying mechanisms
    • Dujardin K, Defebvre L. Apathy in Parkinson's disease: what are the underlying mechanisms. Neurology 2012; 79: 1082-3.
    • (2012) Neurology , vol.79 , pp. 1082-1083
    • Dujardin, K.1    Defebvre, L.2
  • 13
    • 84862149820 scopus 로고    scopus 로고
    • Is depression in Parkinson's disease (PD) a specific entity?
    • Even C, Weintraub D. Is depression in Parkinson's disease (PD) a specific entity? J Affect Disord 2012; 139: 103-12.
    • (2012) J Affect Disord , vol.139 , pp. 103-112
    • Even, C.1    Weintraub, D.2
  • 15
    • 2442680422 scopus 로고    scopus 로고
    • Long term effects of bilateral subthalamic nucleus stimulation on cognitive function, mood, and behaviour in Parkinson's disease
    • Funkiewiez A, Ardouin C, Caputo E, Krack P, Fraix V, Klinger H, et al. Long term effects of bilateral subthalamic nucleus stimulation on cognitive function, mood, and behaviour in Parkinson's disease. J Neurol Neurosurg Psychiatry 2004; 75: 834-9.
    • (2004) J Neurol Neurosurg Psychiatry , vol.75 , pp. 834-839
    • Funkiewiez, A.1    Ardouin, C.2    Caputo, E.3    Krack, P.4    Fraix, V.5    Klinger, H.6
  • 16
    • 84860833881 scopus 로고    scopus 로고
    • Psychosis, apathy, depression and anxiety in Parkinson's disease
    • Gallagher DA, Schrag A. Psychosis, apathy, depression and anxiety in Parkinson's disease. Neurobiol Dis 2012; 46: 581-9.
    • (2012) Neurobiol Dis , vol.46 , pp. 581-589
    • Gallagher, D.A.1    Schrag, A.2
  • 18
    • 0242658923 scopus 로고    scopus 로고
    • Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease
    • Krack P, Batir A, Van Blercom N, Chabardes S, Fraix V, Ardouin C, et al. Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease. N Engl J Med 2003; 349: 1925-34.
    • (2003) N Engl J Med , vol.349 , pp. 1925-1934
    • Krack, P.1    Batir, A.2    Van Blercom, N.3    Chabardes, S.4    Fraix, V.5    Ardouin, C.6
  • 19
    • 60349118998 scopus 로고    scopus 로고
    • The effect of pramipexole on mood and motivational symptoms in Parkinson's disease: A meta-analysis of placebo-controlled studies
    • Leentjens AF, Koester J, Fruh B, Shephard DT, Barone P, Houben JJ. The effect of pramipexole on mood and motivational symptoms in Parkinson's disease: a meta-analysis of placebo-controlled studies. Clin Ther 2009; 31: 89-98.
    • (2009) Clin Ther , vol.31 , pp. 89-98
    • Leentjens, A.F.1    Koester, J.2    Fruh, B.3    Shephard, D.T.4    Barone, P.5    Houben, J.J.6
  • 20
  • 21
    • 33745595886 scopus 로고    scopus 로고
    • Apathy and the functional anatomy of the prefrontal cortex-basal ganglia circuits
    • Levy R, Dubois B. Apathy and the functional anatomy of the prefrontal cortex-basal ganglia circuits. Cereb Cortex 2006; 16: 916-28.
    • (2006) Cereb Cortex , vol.16 , pp. 916-928
    • Levy, R.1    Dubois, B.2
  • 22
    • 84860626797 scopus 로고    scopus 로고
    • Subthalamic stimulation in Parkinson's disease: Restoring the balance of motivated behaviours
    • Lhommé e E, Klinger H, Thobois S, Schmitt E, Ardouin C, Bichon A, et al. Subthalamic stimulation in Parkinson's disease: restoring the balance of motivated behaviours. Brain 2012: 135 (Pt 5): 1463-77.
    • (2012) Brain , vol.135 , Issue.PART 5 , pp. 1463-1477
    • Lhommé, E.E.1    Klinger, H.2    Thobois, S.3    Schmitt, E.4    Ardouin, C.5    Bichon, A.6
  • 23
    • 0032531683 scopus 로고    scopus 로고
    • Electrical stimulation of the subthalamic nucleus in advanced Parkinson's disease
    • Limousin P, Krack P, Pollak P, Benazzouz A, Ardouin C, Hoffmann D, et al. Electrical stimulation of the subthalamic nucleus in advanced Parkinson's disease. N Engl J Med 1998; 339: 1105-11.
    • (1998) N Engl J Med , vol.339 , pp. 1105-1111
    • Limousin, P.1    Krack, P.2    Pollak, P.3    Benazzouz, A.4    Ardouin, C.5    Hoffmann, D.6
  • 24
    • 77957021479 scopus 로고    scopus 로고
    • From the cell to the clinic: A comparative review of the partial D2/D3receptor agonist and 2-adrenoceptor antagonist, piribedil, in the treatment of Parkinson's disease
    • Millan M. From the cell to the clinic: a comparative review of the partial D2/D3receptor agonist and 2-adrenoceptor antagonist, piribedil, in the treatment of Parkinson's disease. Pharmacol Ther 2010; 128: 229-73.
    • (2010) Pharmacol Ther , vol.128 , pp. 229-273
    • Millan, M.1
  • 25
    • 84862326058 scopus 로고    scopus 로고
    • Methylphenidate for gait hypokinesia and freezing in patients with Parkinson's disease undergoing subthalamic stimulation: A multicentre, parallel, randomised, placebo-controlled trial
    • Moreau C, Delval A, Defebvre L, Dujardin K, Duhamel A, Petyt G, et al. Methylphenidate for gait hypokinesia and freezing in patients with Parkinson's disease undergoing subthalamic stimulation: a multicentre, parallel, randomised, placebo-controlled trial. Lancet Neurol 2012; 11: 589-596.
    • (2012) Lancet Neurol , vol.11 , pp. 589-596
    • Moreau, C.1    Delval, A.2    Defebvre, L.3    Dujardin, K.4    Duhamel, A.5    Petyt, G.6
  • 26
    • 84870831762 scopus 로고    scopus 로고
    • Subthalamic nucleus versus globus pallidus bilateral deep brain stimulation for advanced Parkinson's disease (NSTAPS study): A randomised controlled trial
    • Odekerken VJ, van Laar T, Staal MJ, Mosch A, Hoffmann CF, Nijssen PC, et al. Subthalamic nucleus versus globus pallidus bilateral deep brain stimulation for advanced Parkinson's disease (NSTAPS study): a randomised controlled trial. Lancet Neurol 2013; 12: 37-44.
    • (2013) Lancet Neurol , vol.12 , pp. 37-44
    • Odekerken, V.J.1    Van Laar, T.2    Staal, M.J.3    Mosch, A.4    Hoffmann, C.F.5    Nijssen, P.C.6
  • 29
    • 0018142379 scopus 로고
    • Effects of a dopamine agonist piribedil in depressed patients: Relationship of pretreatment homovanillic acid to antidepressant response
    • Post RM, Gerner RH, Carman JS, Gillin JC, Jimerson DC, Goodwin FK, et al. Effects of a dopamine agonist piribedil in depressed patients: relationship of pretreatment homovanillic acid to antidepressant response. Arch Gen Psychiatry 1978; 35: 609-15.
    • (1978) Arch Gen Psychiatry , vol.35 , pp. 609-615
    • Post, R.M.1    Gerner, R.H.2    Carman, J.S.3    Gillin, J.C.4    Jimerson, D.C.5    Goodwin, F.K.6
  • 30
    • 74949088519 scopus 로고    scopus 로고
    • Dopamine agonist withdrawal syndrome in Parkinson disease
    • Rabinak CA, Nirenberg MJ. Dopamine agonist withdrawal syndrome in Parkinson disease. Arch Neurol 2010; 67: 58-63.
    • (2010) Arch Neurol , vol.67 , pp. 58-63
    • Rabinak, C.A.1    Nirenberg, M.J.2
  • 31
    • 33846454323 scopus 로고    scopus 로고
    • Early piribedil monotherapy of Parkinson's disease: A planned seven-month report of the REGAIN study
    • Parkinson REGAIN Study Group
    • Rascol O, Dubois B, Caldas AC, Senn S, Del Signore S, Lees A, Parkinson REGAIN Study Group. Early piribedil monotherapy of Parkinson's disease: A planned seven-month report of the REGAIN study. Mov Disord 2006; 21: 2110-5.
    • (2006) Mov Disord , vol.21 , pp. 2110-2115
    • Rascol, O.1    Dubois, B.2    Caldas, A.C.3    Senn, S.4    Del Signore, S.5    Lees, A.6
  • 32
    • 77649159268 scopus 로고    scopus 로고
    • Orodispersible sublingual piribedil to abort off episodes: A single dose placebo-controlled, randomized, double-blind, cross-over study
    • Rascol O, Azulay JP, Blin O, Bonnet AM, Brefel-Courbon C, Cé saro P, et al. Orodispersible sublingual piribedil to abort OFF episodes: a single dose placebo-controlled, randomized, double-blind, cross-over study. Mov Disord 2010; 25: 368-76.
    • (2010) Mov Disord , vol.25 , pp. 368-376
    • Rascol, O.1    Azulay, J.P.2    Blin, O.3    Bonnet, A.M.4    Brefel-Courbon, C.5    Cé Saro, P.6
  • 33
    • 65849303078 scopus 로고    scopus 로고
    • Effects of ropinirole on nonmotor symptoms of Parkinson disease: A prospective multicenter study
    • Rektorova I, Balaz M, Svatova J, Zarubova K, Honig I, Dostal V, et al. Effects of ropinirole on nonmotor symptoms of Parkinson disease: a prospective multicenter study. Clin Neuropharmacol 2008; 31: 261-6.
    • (2008) Clin Neuropharmacol , vol.31 , pp. 261-266
    • Rektorova, I.1    Balaz, M.2    Svatova, J.3    Zarubova, K.4    Honig, I.5    Dostal, V.6
  • 34
    • 20444477480 scopus 로고    scopus 로고
    • Depression in Parkinson's disease: Loss of dopamine and noradrenaline innervation in the limbic system
    • Remy P, Doder M, Lees A, Turjanski N, Brooks D. Depression in Parkinson's disease: loss of dopamine and noradrenaline innervation in the limbic system. Brain 2005; 128 (Pt 6): 1314-22.
    • (2005) Brain , vol.128 , Issue.PART 6 , pp. 1314-1322
    • Remy, P.1    Doder, M.2    Lees, A.3    Turjanski, N.4    Brooks, D.5
  • 35
    • 0036904309 scopus 로고    scopus 로고
    • The apathy inventory: Assessment of apathy and awareness in Alzheimer's disease, Parkinson's disease and mild cognitive impairment
    • Robert PH, Clairet S, Benoit M, Koutaich J, Bertogliati C, Tible O, et al. The apathy inventory: assessment of apathy and awareness in Alzheimer's disease, Parkinson's disease and mild cognitive impairment. Int J Geriatr Psychiatry 2002; 17: 1099-105.
    • (2002) Int J Geriatr Psychiatry , vol.17 , pp. 1099-1105
    • Robert, P.H.1    Clairet, S.2    Benoit, M.3    Koutaich, J.4    Bertogliati, C.5    Tible, O.6
  • 37
    • 0033875826 scopus 로고    scopus 로고
    • What contributes to quality of life in patients with Parkinson's disease?
    • Schrag A, Jahanshahi M, Quinn N. What contributes to quality of life in patients with Parkinson's disease? J Neurol Neurosurg Psychiatry 2000; 69: 308-12.
    • (2000) J Neurol Neurosurg Psychiatry , vol.69 , pp. 308-312
    • Schrag, A.1    Jahanshahi, M.2    Quinn, N.3
  • 41
    • 84856950829 scopus 로고    scopus 로고
    • Apathy in Parkinson's disease: Diagnostic and etiological dilemmas
    • Starkstein SE. Apathy in Parkinson's disease: diagnostic and etiological dilemmas. Mov Disord 2012; 27: 174-8.
    • (2012) Mov Disord , vol.27 , pp. 174-178
    • Starkstein, S.E.1
  • 42
    • 77950817597 scopus 로고    scopus 로고
    • Non-motor dopamine withdrawal syndrome after surgery for Parkinson's disease: Predictors and underlying mesolimbic denervation
    • Thobois S, Ardouin C, Lhommé e E, Klinger H, Lagrange C, Xie J, et al. Non-motor dopamine withdrawal syndrome after surgery for Parkinson's disease: predictors and underlying mesolimbic denervation. Brain 2010; 133 (Pt 4): 1111-27.
    • (2010) Brain , vol.133 , Issue.PART 4 , pp. 1111-1127
    • Thobois, S.1    Ardouin, C.2    Lhommé, E.E.3    Klinger, H.4    Lagrange, C.5    Xie, J.6
  • 43
    • 72149094883 scopus 로고    scopus 로고
    • Chronic dopaminergic stimulation in Parkinson's disease: From dyskinesias to impulse control disorders
    • Voon V, Fernagut PO, Wickens J, Baunez C, Rodriguez M, Pavon N, et al. Chronic dopaminergic stimulation in Parkinson's disease: from dyskinesias to impulse control disorders. Lancet Neurol 2009; 8: 1140-9.
    • (2009) Lancet Neurol , vol.8 , pp. 1140-1149
    • Voon, V.1    Fernagut, P.O.2    Wickens, J.3    Baunez, C.4    Rodriguez, M.5    Pavon, N.6
  • 44
    • 54949151575 scopus 로고    scopus 로고
    • A multicentre study on suicide outcomes following subthalamic stimulation for Parkinson's disease
    • Voon V, Krack P, Lang AE, Lozano AM, Dujardin K, Schü pbach M, et al. A multicentre study on suicide outcomes following subthalamic stimulation for Parkinson's disease. Brain 2008; 131 (Pt 10): 2720-8.
    • (2008) Brain , vol.131 , Issue.PART 10 , pp. 2720-2728
    • Voon, V.1    Krack, P.2    Lang, A.E.3    Lozano, A.M.4    Dujardin, K.5    Schü Pbach, M.6
  • 45
    • 49849090871 scopus 로고    scopus 로고
    • Neuropsychological and psychiatric changes after deep brain stimulation for Parkinson's disease: A randomised, multicentre study
    • Witt K, Daniels C, Reiff J, Krack P, Volkmann J, Pinsker MO, et al. Neuropsychological and psychiatric changes after deep brain stimulation for Parkinson's disease: a randomised, multicentre study. Lancet Neurol 2008; 7: 605-14.
    • (2008) Lancet Neurol , vol.7 , pp. 605-614
    • Witt, K.1    Daniels, C.2    Reiff, J.3    Krack, P.4    Volkmann, J.5    Pinsker, M.O.6
  • 46
    • 0018175277 scopus 로고
    • A rating scale for mania: Reliability, validity and sensitivity
    • Young RC, Biggs JT, Ziegler VE, Meyer DA. A rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry 1978; 133: 429-35.
    • (1978) Br J Psychiatry , vol.133 , pp. 429-435
    • Young, R.C.1    Biggs, J.T.2    Ziegler, V.E.3    Meyer, D.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.