Perfusion brain SPECT and statistical parametric mapping analysis indicate that apathy is a cingulate syndrome: A study in Alzheimer's disease and nondemented patients

NeuroImage

Volumn 13, Issue 5, 2001, Pages 896-902

  Migneco, O ^a   Benoit, M ^b   Koulibaly, P M ^a   Dygai, I ^a   Bertogliati, C ^b   Desvignes, P ^a   Robert, P H ^b   Malandain, G ^c   Bussiere, F ^a   Darcourt, J ^a  

^a CENTRE ANTOINE LACASSAGNE   (France)

^b PASTEUR HOSPITAL   (France)

^c INRIA   (France)

Author keywords

Apathy; Cingulate; ECD; Statistical parametric mapping

Indexed keywords

CYSTEINE ETHYL ESTER TC 99M;

ADULT; AGED; ALZHEIMER DISEASE; APATHY; ARTICLE; BRAIN MAPPING; BRAIN PERFUSION; BRAIN SCINTISCANNING; CINGULATE GYRUS; CLINICAL ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; FEMALE; HUMAN; MALE; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

EID: 17944362144     PISSN: 10538119     EISSN: None     Source Type: Journal    
DOI: 10.1006/nimg.2000.0741     Document Type: Article

References (52)

1. Alterations of benzodiazepine receptors in type II alcoholic subjects measured with SPECT and [123I]iomazenil
2. Parallel organization of functionally segregation circuits linking basal ganglia and cortex
3. Apathy and depressed mood in acquired brain damage: Relationship to lesion localization and psychophysiological reactivity
4. Hypofrontality in schizophrenia: Distributed dysfunctional circuits in neuroleptic-naive patients
5. The anatomy of melancholia-focal abnormalities of cerebral blood flow in major depression
6. Behavioral and psychological symptoms in Alzheimer's disease relation between apathy and regional cerebral perfusion
7. PET with 18fluorodeoxyglucose and hexamethylpropylene amine oxime SPECT in late whiplash syndrome
8. Personality changes in Alzheimer's disease
9. Anatomie comparée des circonvolutions cérébrales: Le grand lobe limbique et le scissure limbique dans la série des mammifères
10. Prefrontal temporal blood flow in schizophrenia: Resting and activation technetium-99m-MPAO SPECT patterns in young neuroleptic-naive patients with acute disease
11. Frontal-Subcortical circuits
12. Selective and divided attention during visual discriminations of shape, color, and speed: Functional anatomy by positron emission tomography
13. Cerebral blood flow correlates of apathy in Alzheimer disease
14. Abnormal saccadic distractibility in patients with schizophrenia: A 99mTc-HMPAO SPET study
15. Neuropsychiatric aspects of multi-infarct dementia and dementia of the Alzheimer type
16. The Neuropsychiatric Inventory: Comprehensive assessment of psychopathology in dementia
17. Neuropsychiatric syndromes in neurodegenerative diseases: Frequency and significance
18. The Neuropsychiatric Inventory: Assessing psychopathology in dementia patients
19. Contributions of anterior cingulate cortex to behaviour
20. A voxel-based analysis of cerebral perfusion in dementia and depression of old age
21. "Minimental test". A practical method for grading the cognitive state of patients for the clinician
22. Comparing functional (PET) images: The assessment of significant changes
23. Willed action and the prefrontal cortex in man: A study with PET
24. Brain functional activity during gait in normal subjects: A SPECT study
25. Stepwise analysis of cerebral blood flow SPECT imaging on standard brain atlas in patients with dementia of Alzheimer's type
26. Analysis of cerebral blood flow SPECT imaging on standard brain atlas in patients with dementia of Alzheimer type
27. Initiation and supervisory processes in schizophrenia and depression
28. Alzheimer's disease and frontotemporal dementias. Behavioral distinctions
29. Apathy is not depression
30. SPECT imaging of odor identification in schizophrenia
31. Differential diagnosis and classification of apathy
32. Brain mapping with single photon emission CT
33. Paralimbic hypoperfusion in unipolar depression
34. Frontal-subcortical circuits and neuropsychiatric disorders
35. The cingulate and cingulate syndromes
36. The limbic system: An anatomic, phylogenetic, and clinical perspective
37. Associative encoding of pictures activates the medial temporal lobes
38. Brain perfusion abnormalities in Gilles de la Tourette's syndrome
39. The anterior cingulate cortex mediates processing selection in the Stroop attentional conflict paradigm
40. Positron emission tomographic studies of the cortical anatomy of single-word processing
41. Localization of cognitive operations in the human brain
42. Cognitive conjunction: A new approach to brain activation experiments
43. Practice-related changes in human brain functional anatomy during nonmotor learning
44. Neuropsychiatric aspects of cerebrovascular disorders and tumor
45. L'inventaire neuropsychiatrique: Validation de la version Française d'un instrument destiné à évaluer les troubles du comportement chez les sujets déments
46. Accidents vasculaires cérébraux et dépressions
47. Short-term effects of electroconvulsive treatment on the uptake of 99mTc-exametazime into brain in major depression shown with single photon emission tomography
48. Rapid assessment of regional cerebral metabolic abnormalities in single subjects with quantitative and nonquantitative [18F]FDG PET: A clinical validation of statistical parametric mapping
49. Reliability, validity, and clinical correlates of apathy in Parkinson's disease
50. A unified statistical approach for determining significant signals in images of cerebral activation