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Volumn 104, Issue 5, 2014, Pages 334-340

TET enzymes and DNA hydroxymethylation in neural development and function - How critical are they?

Author keywords

5 Hydroxymethylcytosine; Brain; Epigenetic regulation; Neural development; TET enzymes

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; 5 METHYLCYTOSINE; DIOXYGENASE; METHYL GROUP; TET ENZYME; UNCLASSIFIED DRUG; 5-HYDROXYMETHYLCYTOSINE; CYTOSINE; DNA BINDING PROTEIN;

EID: 84927695079     PISSN: 08887543     EISSN: 10898646     Source Type: Journal    
DOI: 10.1016/j.ygeno.2014.08.018     Document Type: Article
Times cited : (82)

References (89)
  • 1
    • 79953892288 scopus 로고    scopus 로고
    • GalR2/3 mediates proliferative and trophic effects of galanin on postnatal hippocampal precursors
    • Abbosh C., Lawkowski A., Zaben M., Gray W. GalR2/3 mediates proliferative and trophic effects of galanin on postnatal hippocampal precursors. J. Neurochem. 2011, 117:425-436.
    • (2011) J. Neurochem. , vol.117 , pp. 425-436
    • Abbosh, C.1    Lawkowski, A.2    Zaben, M.3    Gray, W.4
  • 3
    • 84875129831 scopus 로고    scopus 로고
    • DNA methylation dynamics in health and disease
    • Bergman Y., Cedar H. DNA methylation dynamics in health and disease. Nat. Struct. Mol. Biol. 2013, 20:274-281.
    • (2013) Nat. Struct. Mol. Biol. , vol.20 , pp. 274-281
    • Bergman, Y.1    Cedar, H.2
  • 6
    • 84883393151 scopus 로고    scopus 로고
    • Alteration of genic 5-hydroxymethylcytosine patterning in olfactory neurons correlates with changes in gene expression and cell identity
    • Colquitt B.M., Allen W.E., Barnea G., Lomvardas S. Alteration of genic 5-hydroxymethylcytosine patterning in olfactory neurons correlates with changes in gene expression and cell identity. Proc. Natl. Acad. Sci. U. S. A. 2013, 110:14682-14687.
    • (2013) Proc. Natl. Acad. Sci. U. S. A. , vol.110 , pp. 14682-14687
    • Colquitt, B.M.1    Allen, W.E.2    Barnea, G.3    Lomvardas, S.4
  • 7
    • 80054722415 scopus 로고    scopus 로고
    • Genome-wide screen for differential DNA methylation associated with neural cell differentiation in mouse
    • Cortese R., Lewin J., Backdahl L., Krispin M., Wasserkort R., Eckhardt F., Beck S. Genome-wide screen for differential DNA methylation associated with neural cell differentiation in mouse. PLoS One 2011, 6:e26002.
    • (2011) PLoS One , vol.6 , pp. e26002
    • Cortese, R.1    Lewin, J.2    Backdahl, L.3    Krispin, M.4    Wasserkort, R.5    Eckhardt, F.6    Beck, S.7
  • 11
    • 77951498581 scopus 로고    scopus 로고
    • New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?
    • Deng W., Aimone J.B., Gage F.H. New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?. Nat. Rev. Neurosci. 2010, 11:339-350.
    • (2010) Nat. Rev. Neurosci. , vol.11 , pp. 339-350
    • Deng, W.1    Aimone, J.B.2    Gage, F.H.3
  • 14
    • 16444381345 scopus 로고    scopus 로고
    • Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system
    • Feng J., Chang H., Li E., Fan G. Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system. J. Neurosci. Res. 2005, 79:734-746.
    • (2005) J. Neurosci. Res. , vol.79 , pp. 734-746
    • Feng, J.1    Chang, H.2    Li, E.3    Fan, G.4
  • 15
    • 77950187447 scopus 로고    scopus 로고
    • Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
    • Feng J., Zhou Y., Campbell S.L., Le T., Li E., Sweatt J.D., Silva A.J., Fan G. Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat. Neurosci. 2010, 13:423-430.
    • (2010) Nat. Neurosci. , vol.13 , pp. 423-430
    • Feng, J.1    Zhou, Y.2    Campbell, S.L.3    Le, T.4    Li, E.5    Sweatt, J.D.6    Silva, A.J.7    Fan, G.8
  • 18
    • 77955299096 scopus 로고    scopus 로고
    • High-resolution analysis of parent-of-origin allelic expression in the mouse brain
    • Gregg C., Zhang J., Weissbourd B., Luo S., Schroth G.P., Haig D., Dulac C. High-resolution analysis of parent-of-origin allelic expression in the mouse brain. Science 2010, 329:643-648.
    • (2010) Science , vol.329 , pp. 643-648
    • Gregg, C.1    Zhang, J.2    Weissbourd, B.3    Luo, S.4    Schroth, G.P.5    Haig, D.6    Dulac, C.7
  • 22
    • 79955538247 scopus 로고    scopus 로고
    • Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
    • Guo J.U., Su Y., Zhong C., Ming G.L., Song H. Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell 2011, 145:423-434.
    • (2011) Cell , vol.145 , pp. 423-434
    • Guo, J.U.1    Su, Y.2    Zhong, C.3    Ming, G.L.4    Song, H.5
  • 23
  • 25
    • 84901411259 scopus 로고    scopus 로고
    • Nervous decision-making: to divide or differentiate
    • Hardwick L.J., Philpott A. Nervous decision-making: to divide or differentiate. Trends Genet. 2014, 30:254-261.
    • (2014) Trends Genet. , vol.30 , pp. 254-261
    • Hardwick, L.J.1    Philpott, A.2
  • 27
    • 68049097008 scopus 로고    scopus 로고
    • Epigenetic dynamics of stem cells and cell lineage commitment: digging Waddington's canal
    • Hemberger M., Dean W., Reik W. Epigenetic dynamics of stem cells and cell lineage commitment: digging Waddington's canal. Nat. Rev. Mol. Cell Biol. 2009, 10:526-537.
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 526-537
    • Hemberger, M.1    Dean, W.2    Reik, W.3
  • 31
    • 80054097425 scopus 로고    scopus 로고
    • Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos
    • Inoue A., Zhang Y. Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos. Science 2011, 334:194.
    • (2011) Science , vol.334 , pp. 194
    • Inoue, A.1    Zhang, Y.2
  • 32
    • 79952763586 scopus 로고    scopus 로고
    • Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine
    • Iqbal K., Jin S.G., Pfeifer G.P., Szabo P.E. Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:3642-3647.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 3642-3647
    • Iqbal, K.1    Jin, S.G.2    Pfeifer, G.P.3    Szabo, P.E.4
  • 33
    • 77956189495 scopus 로고    scopus 로고
    • Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
    • Ito S., D'Alessio A.C., Taranova O.V., Hong K., Sowers L.C., Zhang Y. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 2010, 466:1129-1133.
    • (2010) Nature , vol.466 , pp. 1129-1133
    • Ito, S.1    D'Alessio, A.C.2    Taranova, O.V.3    Hong, K.4    Sowers, L.C.5    Zhang, Y.6
  • 34
    • 80052461558 scopus 로고    scopus 로고
    • Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
    • Ito S., Shen L., Dai Q., Wu S.C., Collins L.B., Swenberg J.A., He C., Zhang Y. Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 2011, 333:1300-1303.
    • (2011) Science , vol.333 , pp. 1300-1303
    • Ito, S.1    Shen, L.2    Dai, Q.3    Wu, S.C.4    Collins, L.B.5    Swenberg, J.A.6    He, C.7    Zhang, Y.8
  • 35
    • 79960249232 scopus 로고    scopus 로고
    • Genomic mapping of 5-hydroxymethylcytosine in the human brain
    • Jin S.G., Wu X., Li A.X., Pfeifer G.P. Genomic mapping of 5-hydroxymethylcytosine in the human brain. Nucleic Acids Res. 2011, 39:5015-5024.
    • (2011) Nucleic Acids Res. , vol.39 , pp. 5015-5024
    • Jin, S.G.1    Wu, X.2    Li, A.X.3    Pfeifer, G.P.4
  • 36
    • 84884471932 scopus 로고    scopus 로고
    • TET1 controls CNS 5-methylcytosine hydroxylation, active DNA demethylation, gene transcription, and memory formation
    • Kaas G.A., Zhong C., Eason D.E., Ross D.L., Vachhani R.V., Ming G.L., King J.R., Song H., Sweatt J.D. TET1 controls CNS 5-methylcytosine hydroxylation, active DNA demethylation, gene transcription, and memory formation. Neuron 2013, 79:1086-1093.
    • (2013) Neuron , vol.79 , pp. 1086-1093
    • Kaas, G.A.1    Zhong, C.2    Eason, D.E.3    Ross, D.L.4    Vachhani, R.V.5    Ming, G.L.6    King, J.R.7    Song, H.8    Sweatt, J.D.9
  • 37
    • 79954701341 scopus 로고    scopus 로고
    • Epigenetics and the brain: transcriptome sequencing reveals new depths to genomic imprinting
    • Kelsey G. Epigenetics and the brain: transcriptome sequencing reveals new depths to genomic imprinting. Bioessays 2011, 33:362-367.
    • (2011) Bioessays , vol.33 , pp. 362-367
    • Kelsey, G.1
  • 40
    • 66149123748 scopus 로고    scopus 로고
    • The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
    • Kriaucionis S., Heintz N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 2009, 324:929-930.
    • (2009) Science , vol.324 , pp. 929-930
    • Kriaucionis, S.1    Heintz, N.2
  • 41
    • 74449085394 scopus 로고    scopus 로고
    • The NG2 proteoglycan promotes oligodendrocyte progenitor proliferation and developmental myelination
    • Kucharova K., Stallcup W.B. The NG2 proteoglycan promotes oligodendrocyte progenitor proliferation and developmental myelination. Neuroscience 2010, 166:185-194.
    • (2010) Neuroscience , vol.166 , pp. 185-194
    • Kucharova, K.1    Stallcup, W.B.2
  • 43
    • 84939874278 scopus 로고    scopus 로고
    • Critical role of Tet3 in neural progenitor cell maintenance and terminal differentiation
    • Epub ahead of print
    • Li T., Yang D., Li J., Tang Y., Yang J., Le W. Critical role of Tet3 in neural progenitor cell maintenance and terminal differentiation. Mol. Neurobiol. 2014, Epub ahead of print (http://dx.doi.org/10.1007/s12035-014-8734-5).
    • (2014) Mol. Neurobiol.
    • Li, T.1    Yang, D.2    Li, J.3    Tang, Y.4    Yang, J.5    Le, W.6
  • 45
    • 80052285127 scopus 로고    scopus 로고
    • Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies
    • Li Z., Cai X., Cai C.L., Wang J., Zhang W., Petersen B.E., Yang F.C., Xu M. Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies. Blood 2011, 118:4509-4518.
    • (2011) Blood , vol.118 , pp. 4509-4518
    • Li, Z.1    Cai, X.2    Cai, C.L.3    Wang, J.4    Zhang, W.5    Petersen, B.E.6    Yang, F.C.7    Xu, M.8
  • 49
    • 0346496028 scopus 로고    scopus 로고
    • Gadd45beta is important for perpetuating cognate and inflammatory signals in T cells
    • Lu B., Ferrandino A.F., Flavell R.A. Gadd45beta is important for perpetuating cognate and inflammatory signals in T cells. Nat. Immunol. 2004, 5:38-44.
    • (2004) Nat. Immunol. , vol.5 , pp. 38-44
    • Lu, B.1    Ferrandino, A.F.2    Flavell, R.A.3
  • 50
    • 54849426071 scopus 로고    scopus 로고
    • Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory
    • Lubin F.D., Roth T.L., Sweatt J.D. Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory. J. Neurosci. 2008, 28:10576-10586.
    • (2008) J. Neurosci. , vol.28 , pp. 10576-10586
    • Lubin, F.D.1    Roth, T.L.2    Sweatt, J.D.3
  • 52
    • 0242300612 scopus 로고    scopus 로고
    • DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation
    • Martinowich K., Hattori D., Wu H., Fouse S., He F., Hu Y., Fan G., Sun Y.E. DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science 2003, 302:890-893.
    • (2003) Science , vol.302 , pp. 890-893
    • Martinowich, K.1    Hattori, D.2    Wu, H.3    Fouse, S.4    He, F.5    Hu, Y.6    Fan, G.7    Sun, Y.E.8
  • 53
    • 84871563384 scopus 로고    scopus 로고
    • MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system
    • Mellen M., Ayata P., Dewell S., Kriaucionis S., Heintz N. MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system. Cell 2012, 151:1417-1430.
    • (2012) Cell , vol.151 , pp. 1417-1430
    • Mellen, M.1    Ayata, P.2    Dewell, S.3    Kriaucionis, S.4    Heintz, N.5
  • 54
    • 84877693964 scopus 로고    scopus 로고
    • Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine
    • Minor E.A., Court B.L., Young J.I., Wang G. Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine. J. Biol. Chem. 2013, 288:13669-13674.
    • (2013) J. Biol. Chem. , vol.288 , pp. 13669-13674
    • Minor, E.A.1    Court, B.L.2    Young, J.I.3    Wang, G.4
  • 57
    • 84879386819 scopus 로고    scopus 로고
    • Regulation of lineage specific DNA hypomethylation in mouse trophectoderm
    • Oda M., Oxley D., Dean W., Reik W. Regulation of lineage specific DNA hypomethylation in mouse trophectoderm. PLoS One 2013, 8:e68846.
    • (2013) PLoS One , vol.8 , pp. e68846
    • Oda, M.1    Oxley, D.2    Dean, W.3    Reik, W.4
  • 62
    • 84876946045 scopus 로고    scopus 로고
    • Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics
    • Shen L., Wu H., Diep D., Yamaguchi S., D'Alessio A.C., Fung H.L., Zhang K., Zhang Y. Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics. Cell 2013, 153:692-706.
    • (2013) Cell , vol.153 , pp. 692-706
    • Shen, L.1    Wu, H.2    Diep, D.3    Yamaguchi, S.4    D'Alessio, A.C.5    Fung, H.L.6    Zhang, K.7    Zhang, Y.8
  • 63
    • 84876820776 scopus 로고    scopus 로고
    • Mouse oocyte methylomes at base resolution reveal genome-wide accumulation of non-CpG methylation and role of DNA methyltransferases
    • Shirane K., Toh H., Kobayashi H., Miura F., Chiba H., Ito T., Kono T., Sasaki H. Mouse oocyte methylomes at base resolution reveal genome-wide accumulation of non-CpG methylation and role of DNA methyltransferases. PLoS Genet. 2013, 9:e1003439.
    • (2013) PLoS Genet. , vol.9 , pp. e1003439
    • Shirane, K.1    Toh, H.2    Kobayashi, H.3    Miura, F.4    Chiba, H.5    Ito, T.6    Kono, T.7    Sasaki, H.8
  • 65
    • 84892425393 scopus 로고    scopus 로고
    • The nexus of vitamin homeostasis and DNA synthesis and modification in mammalian brain
    • Spector R., Johanson C.E. The nexus of vitamin homeostasis and DNA synthesis and modification in mammalian brain. Mol. Brain 2014, 7:3.
    • (2014) Mol. Brain , vol.7 , pp. 3
    • Spector, R.1    Johanson, C.E.2
  • 70
    • 84876580885 scopus 로고    scopus 로고
    • Genome-wide comparison of DNA hydroxymethylation in mouse embryonic stem cells and neural progenitor cells by a new comparative hMeDIP-seq method
    • Tan L., Xiong L., Xu W., Wu F., Huang N., Xu Y., Kong L., Zheng L., Schwartz L., Shi Y., Shi Y.G. Genome-wide comparison of DNA hydroxymethylation in mouse embryonic stem cells and neural progenitor cells by a new comparative hMeDIP-seq method. Nucleic Acids Res. 2013, 41:e84.
    • (2013) Nucleic Acids Res. , vol.41 , pp. e84
    • Tan, L.1    Xiong, L.2    Xu, W.3    Wu, F.4    Huang, N.5    Xu, Y.6    Kong, L.7    Zheng, L.8    Schwartz, L.9    Shi, Y.10    Shi, Y.G.11
  • 74
    • 84870856116 scopus 로고    scopus 로고
    • Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum
    • Wang T., Pan Q., Lin L., Szulwach K.E., Song C.X., He C., Wu H., Warren S.T., Jin P., Duan R., Li X. Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum. Hum. Mol. Genet. 2012, 21:5500-5510.
    • (2012) Hum. Mol. Genet. , vol.21 , pp. 5500-5510
    • Wang, T.1    Pan, Q.2    Lin, L.3    Szulwach, K.E.4    Song, C.X.5    He, C.6    Wu, H.7    Warren, S.T.8    Jin, P.9    Duan, R.10    Li, X.11
  • 75
    • 84895911033 scopus 로고    scopus 로고
    • Regulation of TET protein stability by calpains
    • Wang Y., Zhang Y. Regulation of TET protein stability by calpains. Cell Rep. 2014, 6:278-284.
    • (2014) Cell Rep. , vol.6 , pp. 278-284
    • Wang, Y.1    Zhang, Y.2
  • 80
    • 77954842322 scopus 로고    scopus 로고
    • Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes
    • Wu H., Coskun V., Tao J., Xie W., Ge W., Yoshikawa K., Li E., Zhang Y., Sun Y.E. Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes. Science 2010, 329:444-448.
    • (2010) Science , vol.329 , pp. 444-448
    • Wu, H.1    Coskun, V.2    Tao, J.3    Xie, W.4    Ge, W.5    Yoshikawa, K.6    Li, E.7    Zhang, Y.8    Sun, Y.E.9
  • 81
    • 79954457998 scopus 로고    scopus 로고
    • Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells
    • Wu H., D'Alessio A.C., Ito S., Wang Z., Cui K., Zhao K., Sun Y.E., Zhang Y. Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells. Genes Dev. 2011, 25:679-684.
    • (2011) Genes Dev. , vol.25 , pp. 679-684
    • Wu, H.1    D'Alessio, A.C.2    Ito, S.3    Wang, Z.4    Cui, K.5    Zhao, K.6    Sun, Y.E.7    Zhang, Y.8
  • 82
    • 79956292024 scopus 로고    scopus 로고
    • Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells
    • Wu H., D'Alessio A.C., Ito S., Xia K., Wang Z., Cui K., Zhao K., Sun Y.E., Zhang Y. Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells. Nature 2011, 473:389-393.
    • (2011) Nature , vol.473 , pp. 389-393
    • Wu, H.1    D'Alessio, A.C.2    Ito, S.3    Xia, K.4    Wang, Z.5    Cui, K.6    Zhao, K.7    Sun, Y.E.8    Zhang, Y.9
  • 84
    • 84857331867 scopus 로고    scopus 로고
    • Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome
    • Xie W., Barr C.L., Kim A., Yue F., Lee A.Y., Eubanks J., Dempster E.L., Ren B. Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome. Cell 2012, 148:816-831.
    • (2012) Cell , vol.148 , pp. 816-831
    • Xie, W.1    Barr, C.L.2    Kim, A.3    Yue, F.4    Lee, A.Y.5    Eubanks, J.6    Dempster, E.L.7    Ren, B.8
  • 86
    • 84890568163 scopus 로고    scopus 로고
    • Role of Tet1 in erasure of genomic imprinting
    • Yamaguchi S., Shen L., Liu Y., Sendler D., Zhang Y. Role of Tet1 in erasure of genomic imprinting. Nature 2013, 504:460-464.
    • (2013) Nature , vol.504 , pp. 460-464
    • Yamaguchi, S.1    Shen, L.2    Liu, Y.3    Sendler, D.4    Zhang, Y.5
  • 89
    • 84869094967 scopus 로고    scopus 로고
    • Epigenetic mechanisms in learned fear: implications for PTSD
    • Zovkic I.B., Sweatt J.D. Epigenetic mechanisms in learned fear: implications for PTSD. Neuropsychopharmacology 2013, 38:77-93.
    • (2013) Neuropsychopharmacology , vol.38 , pp. 77-93
    • Zovkic, I.B.1    Sweatt, J.D.2


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