MTor mediates tau localization and secretion: Implication for Alzheimer's disease

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1853, Issue 7, 2015, Pages 1646-1657

  Tang, Zhi ^a,b   Ioja, Eniko ^a   Bereczki, Erika ^a   Hultenby, Kjell ^c   Li, Chunxia ^a   Guan, Zhizhong ^a,d   Winblad, Bengt ^a   Pei, Jin Jing ^a,e,f  

^a KAROLINSKA INSTITUTE   (Sweden)

^b GUIZHOU PROVINCIAL PEOPLE'S HOSPITAL   (China)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d GUIZHOU MEDICAL UNIVERSITY   (China)

^e CAPITAL MEDICAL UNIVERSITY   (China)

^f BEIJING INSTITUTE FOR BRAIN DISORDERS   (China)

Author keywords

Alzheimer's disease; Autophagy; MTor; Tau phosphorylation; Tau secretion

Indexed keywords

COLLAGEN TYPE 4; MAMMALIAN TARGET OF RAPAMYCIN; TAU PROTEIN; MTOR PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; AUTOPHAGY; CELL VACUOLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOPLASM; CYTOSOLIC FRACTION; ENDOPLASMIC RETICULUM; FEMALE; GOLGI COMPLEX; HIPPOCAMPAL CA1 REGION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOELECTRON MICROSCOPY; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SPACE; MALE; MIDDLE AGED; MITOCHONDRION; NEUROBLASTOMA; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN SECRETION; PROTEIN SYNTHESIS; UPREGULATION; VERY ELDERLY; WESTERN BLOTTING; CELL FRACTIONATION; CELL MEMBRANE; CYTOSOL; EXOSOME; METABOLISM; NERVE CELL; NEUROFIBRILLARY TANGLE; PATHOLOGY; PROTEIN TRANSPORT; PROTEINOSIS; SECRETION (PROCESS); TUMOR CELL LINE; ULTRASTRUCTURE;

MAMMALIA;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AUTOPHAGY; CELL LINE, TUMOR; CELL MEMBRANE; CYTOSOL; ENDOPLASMIC RETICULUM; EXOSOMES; FEMALE; GOLGI APPARATUS; HUMANS; INTRACELLULAR SPACE; MALE; MIDDLE AGED; MITOCHONDRIA; NEUROFIBRILLARY TANGLES; NEURONS; PROTEIN AGGREGATION, PATHOLOGICAL; PROTEIN TRANSPORT; SUBCELLULAR FRACTIONS; TAU PROTEINS; TOR SERINE-THREONINE KINASES; UP-REGULATION; VACUOLES;

EID: 84927643922     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2015.03.003     Document Type: Article

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