Deviations from the Expectable Environment in Early Childhood and Emerging Psychopathology

Neuropsychopharmacology

Volumn 40, Issue 1, 2015, Pages 154-170

  Humphreys, Kathryn L ^a   Zeanah, Charles H ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHILD; CHILD DEVELOPMENT; DEVELOPMENTAL DISABILITIES; HUMAN; MENTAL DISEASE; MENTAL DISORDERS; PHYSIOLOGY; PRESCHOOL CHILD; PSYCHOLOGY; SOCIAL ENVIRONMENT;

CHILD; CHILD DEVELOPMENT; CHILD, PRESCHOOL; DEVELOPMENTAL DISABILITIES; HUMANS; MENTAL DISORDERS; PSYCHOPATHOLOGY; SOCIAL ENVIRONMENT;

EID: 84926623581     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2014.165     Document Type: Review

References (194)

1. Achenbach TM (1991). Integrative guide for the 1991 CBCL/4-18, YSR, and TRF profiles. University of Vermont.
2. Alizadeh H, Applequist KF, Coolidge FL (2007). Parental self-confidence, parenting styles, and corporal punishment in families of ADHD children in Iran. Child Abus Negl 31: 567-572.
3. American Psychiatric Association (2013). Diagnostic and Statistical Manual of Mental Disorders. 5th Edition (DSM-5). American Psychiatric Publishing.
4. Bakermans-Kranenburg MJ, Steele H, Zeanah CH, Muhamedrahimov RJ, Vorria P, Dobrova-Krol NA et al (2011). Attachmen t and emotional development in institutional care: Characteristics and catch up. Monogr Soc Res Child Dev 76: 62-91.
5. Bauer PM, Hanson JL, Pierson RK, Davidson RJ, Pollak SD (2009). Cerebellar volume and cognitive functioning in children who experienced early deprivation. Biol Psychiatry 66: 1100-1106.
6. Baumrind D (1993). The average expectable environment is not good enough: A response to Scarr. Child Dev 64: 1299-1317.
7. Becker-Blease KA, Freyd JJ (2008). A preliminary study of ADHD symptoms and correlates: Do abused children differ from nonabused children? J Aggress Maltreat Trauma 17: 133-140.
8. Ben-Shlomo Y, Kuh D (2002). A life course approach to chronic disease epidemiology: Conceptual models, empirical challenges and interdisciplinary perspectives. Int J Epidemiol 31: 285-293.
9. Boden JM, Fergusson DM, Horwood LJ (2010). Risk factors for conduct disorder and oppositional/defiant disorder: Evidence from a New Zealand birth cohort. J Am Acad Child Adolesc Psychiatry 49: 1125-1133.
10. Boggs SR, E yberg SM, Edwards DL, Rayfield A, Jacobs J, Bagner D et al (2005). Outcomes of parent-child interaction therapy: A comparison of treatment completers and study dropouts one to three years later. Child Fam Behav Ther 26: 1-22.
11. Bolger KE, Patterson CJ (2001). Pathways from child maltreatment to internalizing problems: Perceptions of control as mediators and moderators. Dev Psychopathol 13: 913-940.
12. Bomy ea J, Risbrough V, Lang AJ (2012). A consideration of select pre-trauma factors as key vulnerabilities in PTSD. Clin Psychol Rev 32: 630-641.
13. Boris NW, Hinshaw-Fuselier SS, Smyke AT, Scheeringa MS, Heller SS, Zeanah CH (2004). Comparing criteria for attachment disorders: Establishing reliability and validity in high-risk samples. J Am Acad Child Adolesc Psychiatry 43: 568-577.
14. Bos KJ, Fox N, Zeanah CH, Nelson CA (2009). Effects of early psychosocial deprivation on the development of memory and executive function. Front Behav Neurosci 3: 16.
15. Bowlby J (2008). A Secure Base: Parent-Child Attachment and Healthy Human Development. Basic Books.
16. Boyce WT, Ellis BJ (2005). Biological sensitivity to context: I. An evolutionarydevelopmental theory of the origins and functions of stress reactivity. Dev Psychopathol 17: 271-301.
17. Brett ZH, Humphreys KL, Fleming AS, Kraemer GW, Drury SS. (in press-a). Using cross species comparisons and a neurobiological framework to understand earl y social deprivation effects on behavioral development. Dev Psychopathol.
18. Brett ZH, Humphreys KL, Smyke AT, Gleason MM, Nelson CA, Zeanah CH et al (in press-b). 5HTTLPR genotype moderates the longitudi nal impact of early caregiving on externalizing behavior. Dev Psychopathol.
19. Briscoe-Smith AM Hinshaw SP 2006 Linkages between child abuse and attention-deficit/hyperactivity disorder in girls: Behavioral and social cor relates. Child Abus Negl 30 1239-1255.
20. Bruce J, Tarullo AR, Gunnar MR (2009). Disinhibited social behavior among internationally adopted children. Dev Psychopathol 21: 157-171.
21. Carlson EA, Jacobvitz D, Sroufe La (1995). A developmental investigation of inattentiveness and hyperactivity. Child Dev 66: 37-54.
22. Carlson M, Earls F (1997). Psychological and neuroendocrinological sequelae of early social deprivation in institutionalized children in Romania. Ann N Y Acad Sci 807: 419-428.
23. Carrion VG, Weems CF, Eliez S, Patwardhan A, Brown W, Ray RD et al (2001). A ttenuation of frontal asymmetry in pediatric posttraumatic stress disorder. Biol Psychiatry 50: 943-951.
24. Cartmill EA, Armstrong BF, Gleitman LR, Goldin-Meadow S, Medina TN, Trueswell JC (2013). Qual ity of early parent input predicts child vocabulary 3 years later. Proc Natl Acad Sci USA 110: 11278-11283.
25. Chisholm K (1998). A three year follow-up of attachment and indiscriminate friendliness in children adopted from Romanian orphanages. Child Dev 69: 1092-1106.
26. Chugani HT, Behen ME, Muzik O, Juhá sz C, Nagy F, Chugani DC (2001). Local brain functional activity following early deprivation: A study of postinstitu tionalized Romanian orphans. Neuroimage 14: 1290-1301.
27. Cicchetti D, Rogosch FA (2001). The impact of child maltreatment and psychopathology on neuroendocrine functioning. Dev Psychopathol 13: 783-804.
28. Cicchetti D, Rogosch FA (2010). The differential impacts of early physical and sexual abuse and internalizing problems on daytime cortisol rhythm in school-aged children. Child Dev 81: 252-269.
29. Conway F, Oster M, Szymanski K (2011). ADHD and complex trauma: A descriptive study of hospitalized children in an urban psychiatric hospital. J Infant, Child, Adolesc Psychother 10: 60-72.
30. Curtis WJ, Lindeke LL, Georgieff MK, Nelson CA (2002). Neurobehavioural functioning in neonatal intensive care unit graduates in late childhood and early adolescence. Brain 125: 1646-1659.
31. Cutajar MC, Mullen P E, Ogloff JRP, Thomas SD, Wells DL, Spataro J (2010). Psychopathology in a large cohort of sexually abused children followed up to 43 years. Child Abus Negl 34: 813-822.
32. Dalgleish T, Moradi AR, Taghavi MR, Neshat-Doost HT, Yule W (2001). An experimental investigation of hypervigilance for threat in children and adolescents with post-traumatic stress disorder. Psychol Med 31: 541-547.
33. De Bellis MD (2001). Developmental traumatology: The psychobiological development of maltreated children and its implications for research, treatment, and policy. Dev Psychopathol 13: 539-564.
34. De Bellis MD, Baum AS, Bir maher B, Keshavan MS, Eccard CH, Boring AM et al (1999). Developmental traumatology part I: Biological stress systems. Biol Psychiatry 45: 1259-1270.
35. De Bellis MD, Hall J, Boring AM, Fru staci K, Moritz G (2001). A pilot longitudinal study of hippocampal volumes in pediatric maltreatment-related posttraumatic stress disorder. Biol Psychiatry 50: 305-309.
36. De Bellis MD, Keshavan MS, Shiff lett H, Iyengar S, Beers SR, Hall J et al (2002). Brain structures in pediatric maltreatment-related posttraumatic stress disorder: A sociodemographically matched study. Biol Psychiatry 52: 1066-1078.
37. De Bellis MD, Zisk A (2014). The biological effects of childhood trauma. Child Adolesc Psychiatr Clin N Am 23: 185-222.
38. Dodge KA, Pettit GS, Bates JE, Valente E (1995). Social information-pr ocessing patterns partially mediate the effect of early physical abuse on later conduct problems. J Abnorm Psychol 104: 632-643.
39. D'Onofrio BM, Van Hulle CA, Waldman ID, Rodgers JL, Rathouz PJ, Lahey BB ( 2007). Causal inferences regarding prenatal alcohol exposure and childhood externalizing problems. Arch Gen Psychiatry 64: 1296-1304.
40. Dong M Anda R Felitti V 2004 The interrelatedness of multiple forms of childhood abuse, neglect, and household dysfunction Child Abuse Negl 28 771-784.
41. Dozier M, Manni M, Gordon MK, Peloso E, Gunnar MR, Stovall-McClough KC et al (2006). Foster ch ildren's diurnal production of cortisol: An exploratory study. Child Maltreat 11: 189-197.
42. Drury SS, Gleason MM, Theall KP, Smyke AT, Nelson CA, Fox NA et al (2012a). Genetic sensitivity to the caregiving context: The influence of 5httlpr and BDNF val66met on indiscriminate social behavior. Physiol Beha v 106: 728-735.
43. Drury SS, Theall K, Gleason M, Smyke AT, De Vivo I, Wong J et al (2012b). Telomere length and early severe social deprivation: Linking early adversity and cellular aging. Mol Psy chiatry 17: 719-727.
44. Drury SS, Theall KP, Smyke AT, Keats BJB, Egger HL, Nelson CA et al (2010). Modification of depression by COMT val158met polymorphism in children exposed to early severe psychoso cial deprivation. Child Abus Negl 34: 387-395.
45. Durston S, Thomas KM, Yang Y, Ulu AM, Zimmerman RD, Casey BJ (2002). A neural basis for the development of inhibitory control. Dev Sci 5: F9-F16.
46. Egger HL, Erkanli A, Keeler G, Potts E, Walter BK, Angold A (2006). Test-retest reliability of the preschool age psychiatric assessment (PAPA). J Am Acad Child Adolesc Psychiatry 45: 538-549.
47. Ellis BH, Fisher PA, Zaharie S (2004). Predictors of disruptive behavior, developmental delays, anxiety, and affective symptomatology among institutionally reared Romanian children. J Am Acad Child Adolesc Psychiatry 43: 1283-1292.
48. Eluvathingal TJ, Chugani HT, Behen ME, Juhá sz C, Muzik O, Maqbool M et al (2006). Abnormal brain connectivity in children after early severe socioemotional deprivation: A diffusion tensor imaging study. Pediatrics 117: 2093-2100.
49. Eyberg SM, Nelson MM, Boggs SR (2008). Evidence-based psychosocial treatments for children and adolescents with disruptive behavior. J Clin Child Adolesc Psychol 37: 215-237.
50. Fairchild G, Passamonti L, Hurford G, Hagan CC, von dem Hagen EAH, Van Goozen SHM et al (2011). Brain structure abnormalities in early-onset and adolescent-onset conduct disorder. Am J Psychiatry 168: 624-633.
51. Fantuzzo JW, delGaudio Weiss A, Atkins M, Meyers R, Noone M (1998). A contextually relevant assessment of the impact of child maltreatment on the social competencies of low-income urban children. J Am Acad Chil d Adolesc Psychiatry 37: 1201-1208.
52. Fergusson DM, Boden JM, Horwood LJ (2008). Exposure to childhood sexual and physical abuse and adjustment in early adulthood. Child Abus Negl 32: 607-619.
53. Field T (1994). The effects of mother's physical and emotional unavailability on emotion regulation. Monogr Soc Res Child Dev 59: 208-227.
54. Ford JD, Racusin R, Ellis CG, Daviss WB, Reise r J, Fleischer A et al (2000). Child maltreatment, other trauma exposure, and posttraumatic symptomatology among children with oppositional defiant and attention deficit hyperactivity disorders. Child Maltreat 5: 205-217.
55. Ford JD, Stockton P, Kaltman S, Green BL (2006). Disorders of extreme stress (DESNOS) symptoms are associated with type and severity of interpersonal trauma exposure in a sample of healthy young women. J Interpers Violence 21: 1399-1416.
56. Frick PJ, Nigg JT (2012). Current issues in the diagnosis of attention deficit hyperactivity disorder, oppositional defiant disorder, and conduct disorder. Annu Rev Clin Psychol 8: 77-107.
57. Fox SE, Levitt P, Nelson CA (2010). How the timing and quality of early experiences influence the development of brain architecture. Child Dev 81: 28-40.
58. Gee DG, Gabard-Durnam LJ, Flannery J, Goff B, Humphreys KL, Telzer EH et al (2013). Early developmental emergence of human amygdala-prefrontal connectivity after maternal deprivation. Proc Natl Acad Sci USA 110: 15638-15643.
59. Ghera MM, Marshall PJ, Fox N a, Zeanah CH, Nelson C a, Smyke AT et al (2009). The effects of foster care intervention on socially deprived institutionalized children's attention and positive affect: Results from the BEIP study. J Child Psychol Psychiatry 50: 246-253.
60. Gleason MM, Fox NA, Drury S, Smyke A, Egger HL, Nelson CA et al (2011a). Validity of evidence-derived criteria for reactive attachment disorder: Indiscriminately social/disinhibited and emotionally withdrawn/inhibited types. J Am Acad Child Adolesc Psychiatry 50: 216-231.
61. Gleason MM Zamfirescu A Egger HL Nelson C.A. Fox N.A. Zeanah CH (2011b)Epidemiology of psychiatric disorders in very young children in a Romanian pediatric setting. Eur Child Adolesc Psychiatry 20 527-535.
62. Goldfarb W (1945). Psychological privation in infancy and subsequent adjustment. Am J Orthopsychiatry 15: 247-255.
63. Govindan RM, Behen ME, Helder E, Makki MI, Chugani HT (2010). Altered water diffusivity in cortical association tracts in children with early deprivation identified with Tract-Based Spatial Statistics (TBSS). Cereb Cortex 20: 561-569.
64. Greenough WT, Black JE, Wallace CS (1987). Experience and brain development. Child Dev 58: 539-559.
65. Gunnar MR, Bruce J, Grotevant HD (2000). International adoption of institutionally reared children: Research and policy. Dev Psychopathol 12: 677-693.
66. Gunnar MR, Morison SJ, Chisholm K, Schuder M (2001). Salivary cortisol levels in children adopted from romanian orphanages. Dev Psychopathol 13: 611-628.
67. Gunnar MR, Van Dulmen M. International Adoption Project Team (2007). Behavior problems in post-institutionalized internationally adopted children. Dev Psychopathol 19: 129-148.
68. Hakamata Y, Lissek S, Bar-Haim Y, Britton JC, Fox NA, Leibenluft E et al (2010). Attention bias modification treatment: A meta-analysis toward the establishment of novel treatment for anxiety. Biol Psych iatry 68: 982-990.
69. Halfon N, Hochstein M (2002). Life course health development: An integrated framework for developing health, policy, and research. Milbank Q 80: 433-479.
70. Hart B, Risley TR (1995). Meaningful Differences in the Everyday Experience of Young American Children. Brookes: Baltimore, MD.
71. Heneghan A, Stein REK, Hurlburt MS, Zhang J, Rolls-Reutz J, Fisher E et al (2013). Mental health problems in teens investigated by U.S. child welfare agencies. J Adolesc Heal 52: 634-640.
72. Hertzman C, Wiens M (1996). Child development and long-term outcomes: A population health perspective and summary of successful interventions. Soc Sci Med 43: 1083-1095.
73. Humphreys KL, Zeanah CH, Scheeringa MS. (in press). Infant development. The first 3 years of life. In: Tasman A, Kay J, Lieberman JA, First MB, Riba M (eds). Psychiatry. 4th edn, Wiley-Blackwell.
74. Hunt JM (1979). Psychological development: Early experience. Annu Rev Psychol 30: 103-144.
75. Jack owski AP, Douglas-Palumberi H, Jackowski M, Win L, Schultz RT, Staib LW et al (2008). Corpus callosum in maltreated children with PTSD: A diffusion tensor imaging study. Psychiatry Res 162: 256-261.
76. Johnson DE, Guthrie D, Smyke AT, Koga SF, Fox NA, Zeanah CH et al (2010). Growth and associations between auxology, caregiving environment, and cognition in socially deprived Romanian children randomized to foster vs o ngoing institutional care. Arch Pediatr Adolesc Med 164: 507-516.
77. Jones AP, Laurens KR, Herba CM, Barker GJ, Viding E (2009). Amygdala hypoactivity to fearful faces in boys with conduct problems and callousunemotional traits. Am J Psychiatry 166: 95-102.
78. Jones W, Bellugi U, Lai Z, Chiles M, Reilly J, Lincoln A et al (2000). Hypersociability in Williams syndrome. J Cogn Neurosci 12: 30-46.
79. Jonson-Reid M, Kohl PL, Drake B (2012). Child and adult outcomes of chronic child maltreatment. Pediatrics 129: 839-845.
80. Kaplow JB, Widom CS (2007). Age of onset of child maltreatment predicts longterm mental health outcomes. J Abnorm Psychol 116: 176-187.
81. Kearney CA, Wechsler A, Kaur H, Lemos-Miller A (2010). Posttraumatic stress disorder in maltreated youth: A r eview of contemporary research and thought. Clin Child Fam Psychol Rev 13: 46-76.
82. Keiley MK, Howe TR, Dodge KA, Bates JE, Petti GS (2001). The timing of child physical maltreatment: A cross-domain g rowth analysis of impact on adolescent externalizing and internalizing problems. Dev Psychopathol 13: 891-912.
83. Kessler RC Sonnega A Bromet E Hughes M Nelson CB 1995 Posttraumatic stress disorder in the National Comorbidity Survey.Arch Gen Psychiatry 52 1048-1060.
84. Kim J, Cicchetti D (2010). Longitudinal pathways linking child maltreatment, emotion regulation, peer relations, and psychopathology. J Child Psychol Psychiatry 51: 706-716.
85. Kim-Cohen J, Caspi A, T aylor A, Williams B, Newcombe R, Craig IW et al (2006). MAOA, maltreatment, and gene-environment interaction predicting children's mental health: New evidence and a meta-analysis. Mol Psychiatry 11: 903-913.
86. Knudsen EI (2004). Sensitive periods in the development of the brain and behavior. J Cogn Neurosci 16: 1412-1425.
87. Kolko DJ, Hurlburt MS, Zhang J, Barth RP, Leslie LK, Burns BJ (2010). Posttraumatic stress symptoms in children and adolescents referred for child welfare investigation. A national sample of in-home and out-of-home care. Chi ld Maltreat 15: 48-63.
88. Kotch JB, Lewis T, Hussey JM, English D, Thompson R, Litrownik AJ et al (2008). Importance of early neglect for childhood aggression. Pediatrics 121: 725-731.
89. Kreppner JM, O'Connor TG, Rutter M (2001). Can inattention/overactivity be an institutional deprivation syndrome? J Abnorm Child Psychol 29: 513-528.
90. Kreppner JM, Rutter M, Beckett C, Castle J, Colvert E, Groothues C et al (2007). Normality and impairment following profound early institutional deprivation: A longitudinal follow-up into early adolescence. Dev Psychol 43: 931-946.
91. Lansford JE, Dodge K, Pettit GS, Bates JE, Crozier J, Kaplow J (2002). A 12-year prospective study of the long-term effects of early child physical maltreatment on psychological, behavioral, and academic problems in adolescen ce. Arch Pediatr Adolesc Med 156: 824-830.
92. Lawler JM, Hostinar CE, Miliner SB, Gunnar MR (2014). Disinhibited social engagement in postinstitutionalized children: Differentiating normal from atypical behavio r. Dev Psychopathol 26: 451-461.
93. Lerner RM, Overton WF (2008). Exemplifying the integrations of the relational developmental system: Synthesizing theory, research, and application to promote positive developmen t and social justice. J Adolesc Res 23: 245-255.
94. Levy F, Hay DA, McStephen M, Wood C, Waldman I (1997). Attention-deficit hyperactivity disorder: A category or a continuum? Genetic analysis of a largescale twin study. J Am Acad Child Adolesc Psychiatry 36: 737-744.
95. Lewis EE, Dozier M, Ackerman J, Sepulveda-Kozakowski S (2007). The effect of placement instability on adopted children's inhibito ry control abilities and oppositional behavior. Dev Psychol 43: 1415-1427.
96. Li JJ, Lee SS (2012). Interaction of dopamine transporter (DAT1) genotype and maltreatment for ADHD: A latent class analysis. J Child Psychol Psychiatry 53: 997-1005.
97. Lifford KJ, Harold GT, Thapar A (2008). Parent-child relationships and ADHD symptoms: A longitudinal analysis. J Abnorm Child Psychol 36: 285-296.
98. Loman MM, Johnson AE, Westerlund A, Pollak SD, Nelson CA, Gunnar MR (2013). The effect of early deprivation on executive attention in middle childhood. J Child Psychol Psychiatry 54: 37-45.
99. Lupien SJ, McEwen BS, Gunnar MR, Heim C (2009). Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nat Rev Neurosci 10: 434-445.
100. Lyons-Ruth K, Bureau JF, Riley CD , Atlas-Corbett AF (2009). Socially indiscriminate attachment behavior in the strange situation: Convergent and discriminant validity in relation to caregiving risk, later behavior problems, and attachment insecurity. Dev Psychopathol 2 1: 355-372.
101. Maestripieri D, Carroll KA (1998). Child abuse and neglect: Usefulness of the animal data. Psychol Bull 123: 211-223.
102. Manly JT, Kim JE, Rogosch FA, Cicchetti D (2001). Dimensions of child maltreatment and children's adjustment: Contributions of developmental timing and subtype. Dev Psychopathol 13: 759-782.
103. Marcus DK, Barry TD (2011). Does attention-deficit/hyperactivity disorder have a dimensional latent structure? A taxometric analysis. J Abnorm Psychol 120: 427-442.
104. Marshall PJ Fox N.A. BEIP Core Group 2004 A comparison of the electroencephalogram between institutionalized and community children in Romania J Cogn Neurosci 16 1327-1338.
105. Marshall PJ, Reeb BC, Fox NA, Nelson CA, Zeanah CH (2008). Effects of early intervention on EEG power and coherence in pr eviously institutionalized children in Romania. Dev Psychopathol 20: 861-880.
106. McCrory EJ, De Brito SA, Sebastian CL, Mechelli A, Bird G, Kelly PA et al (2011). Heightened neural reactivity to th reat in child victims of family violence. Curr Biol 21: R947-R948.
107. McEwen BS (1998). Stress, adaptation, and disease. Allostasis and allostatic load. Ann N Y Acad Sci 840: 33-44.
108. Mc Ewen BS, Seeman T (1999). Protective and damaging effects of mediators of stress. Elaborating and testing the concepts of allostasis and allostatic load. Ann N Y Acad Sci 896: 30-47.
109. McGoron L, Zeanah CH, Frick PJ, Nelson CA, Fox NA (2013). Callous-unemotional traits in children with a history of institutional care. Fifth Biennial Meeting for Scientific Study of Psychopathy.
110. McLaughlin KA, Fox NA, Zeanah CH, Sheri dan MA, Marshall P, Nelson CA (2010). Delayed maturation in brain electrical activity partially explains the association between early environmental deprivation and symptoms of attention-deficit/hyperactivity disorder. Biol Psychiatry 68: 329-336.
111. McLaughlin KA, Sheridan MA, Lambert HK (2014). Childhood adversity and neural development: Deprivation and threat as distinct dimensions of early experience. Manuscript under Editorial Review.
112. McLaughlin KA, Sheridan MA, Winter W, Fox NA, Zeanah CH, Nelson CA (2013). Widespread reductions in cortical thickness following severe early-life deprivation: A neurodevelopmental pathway to attention-deficit/hyperactivit y disorder. Biol Psychiatry print copy in press (originally published online 30 September 2013, at http://www.biologicalpsychiatryjournal.com/article/S0006-3223(13)00769-5/
113. Mehta MA, Golembo NI, Nosarti C, Colvert E, Mota A, Williams SCR et al (2009). Amygdala, hippocampal and corpus callosum size following severe early institutional deprivation: The English and Romanian Adoptees study pilot. J Child Psychol Psychiatry 50: 943-95 1.
114. Mennen FE, Kim K, Sang J, Trickett PK (2010). Child neglect: Definition and identification of youth's experiences in official reports of maltreatment. Child Abus Negl 34: 647-658.
115. Miller L , Chan W, Litvinova A (2006). Fetal alcohol spectrum disorders in children residing in Russian orphanages: A phenotypic survey. Alcohol Clin Exp Res 30: 531-538.
116. Murray-Close D, Han G, Cicchetti D, Crick NR, Rogosch FA (2008). Neuroendocrine regulation and physical and relational aggression: The moderating roles of child maltreatment and gender. Dev Psychol 44: 1160-1176.
117. Narr KL, Woods RP, Li n J, Kim J, Phillips OR, Del'Homme M et al (2009). Widespread cortical thinning is a robust anatomical marker for attentiondeficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry 48: 1014-1022.
118. National Research Council (2013). New Directions in Child Abuse and Neglect Research. National Academies Press.
119. Nelson CA, Bos K, Gunnar MR, Sonuga-Barke EJ (2011). The neurobiological toll of early human deprivation. Monogr Soc Res Child Dev 76: 127-146.
120. Nelson CA, Fox NA, Zeanah CH (2014). Romania's Abandoned Children. Harvard University Press.
121. Neubauer S, Hublin J-J (2012). The evolution of human brain development. Evol Biol 39: 568-586.
122. O'Connor TG, Marvin RS, Rutter M, Olrick JT, Britner PA (2003). Childparent attachment following early institutional deprivation. Dev Psychopathol 15: 19-38.
123. Olsavsky AK, Telzer EH, Shapiro M, Humphreys KL, Flannery J, Goff B et al (2013). Indiscriminate amygdala response to mothers and strangers after early maternal deprivation. Biol Psychiatry 74: 853-860.
124. Oosterman M, Schuengel C, Wim Slot N, Bullens RAR, Doreleijers TAH (2007). Disruptions in foster care: A review and meta-analysis. Child Youth Serv Rev 29: 53-76.
125. Ouyang L Fang X Mercy J Perou R Grosse SD 2008Attention-/hyperactivity disorder symptoms and child maltreatment: A population-based studyJ Pediatr 153 851-856.
126. Passamonti L, Fairchild G, Fornito A, Goodyer IM, Nimmo-Smith I, Hagan CC et al (2012). Abnormal anatomical connectivity between the amygdala and orbitofrontal cortex in conduct disorder. PLoS One 7: E 48789.
127. Patterson GR (2002). The early development of coercive family process. In: Reid JB, Patterson GR, Snyder J (eds). Antisocial Behavior in Children and Adolescents: Developmental Theories and Models for Intervention. American Psychological Association: Washington, DC, pp 25-44.
128. Pears KC, Bruce J, Fisher PA, Kim HK (2010). Indiscriminate friendliness in maltreated foster children. Child Maltreat 15: 64-75.
129. Pine DS, Mogg K, Bradley BP, Montgomery L, Monk CS, McClure E et al (2005). Attention bias to threat in maltreated children: Implications for vulnerability to stress-related psychopathology. Am J Psychiatry 162: 291-296.
130. Polanczyk G, De Lima MS, Hor ta BL, Biederman J, Rohde La (2007). The worldwide prevalence of ADHD: A systematic review and metaregression analysis. Am J Psychiatry 164: 942-948.
131. Pollak SD, Cicchetti D, Klorman R, Brumaghim JT (1997). Cognitive brain eventrelated potentials and emotion processing in maltreated children. Child Dev 68: 773-787.
132. Pollak SD, Klorman R, Thatcher JE, Cicchetti D (2001). P3b reflects maltreated children's reactions to facial displays of emotion. Psychophysiology 38: 267-274.
133. Pollak SD, Sinha P (2002). Effects of early experience on children's recognition of facial displays of emotion. Dev Psychol 38: 784-791.
134. Pollak SD, Tolley-Schell SA (2003). Selective attention to facial emotion in physically abused children. J Abnorm Psychol 112: 323-338.
135. Richert KA, Carrion VG, Karchemskiy A, Reiss AL (2006). Regional differences of the prefrontal cortex in pediatric PTSD: An MRI study. Depress Anxiety 25: 17-25.
136. Romens SE, Svaren J, Pollak SD. (in press). Associations between early life stress and gene methylation in children. Child Dev.
137. Roy P, Rutter M, Pickles A (2004). Institutional care: Associations between overactivity and lack of selectivity in social relationships. J Child Psychol Psychiatry 45: 866-873.
138. Rutter M, Kreppner J, Sonuga-Barke E (2009). Emanuel Miller lecture: Attachment insecurity, disinhibited attachment, and attachment disorders: Where do resear ch findings leave the concepts? J Child Psychol Psychiatry 50: 529-543.
139. Rutter M, Sonuga-Barke EJ, Beckett C, Bell CA, Kreppner J, Kumsta R et al (2010a). Deprivation-specific psychological patterns: Effects of institutional deprivation by the English and Romanian Adoptee Study Team. Monogr Soc Res Child Dev 75: 1-252.
140. Rutter M, Sonuga-Barke EJ, Castle J (2010b). I. Investigating the impact of early institutional deprivation on development: Background and research strategy of the English and Romanian Adoptees (ERA) study. Monogr Soc Res Child D ev 75: 1-20.
141. Sameroff AJ, Chandler MJ (1975). Reproductive risk and the continuum of caretaking casualty. Rev Child Dev Res 4: 187-244.
142. Scarr S (1992). Developmental th eories for the 1990s: Development and individual differences. Child Dev 63: 1-19.
143. Scheeringa MS, Wright MJ, Hunt JP, Zeanah CH (2006). Factors affecting the diagnosis and prediction of PTSD symptomatolo gy in children and adolescents. Am J Psychiatry 163: 644-651.
144. Scheeringa MS, Zeanah CH (1995). Symptom expression and trauma variables in children under 48 months of age. Infant Ment Health J 16: 259-270.
145. Scheeringa MS, Zeanah CH, Cohen JA (2011). PTSD in children and adolescents: Toward an empirically based algorithma. Depress Anxiety 28: 770-782.
146. Scheeringa MS, Zeanah CH, My ers L, Putnam FW (2003). New findings on alternative criteria for PTSD in preschool children. J Am Acad Child Adolesc Psychiatry 42: 561-570.
147. Shackman JE Shackman AJ Pollak SD 2007 Physical abuse amplifies attention to threat and increases anxiety in children Emotion 7 838-852.
148. Shalev I, Moffitt TE, Sugden K, Williams B, Houts RM, Danese A et al (2012). Exposure to violence dur ing childhood is associated with telomere erosion from 5 to 10 years of age: A longitudinal study. Mol Psychiatry 18: 576-581.
149. Shaw DS, Hyde LW, Brennan LM (2012). Early predictors of boys' antisocial trajectories. Dev Psychopathol 24: 871-888.
150. Shaw P, Lerch J, Greenstein D, Sharp W, Clasen L, Evans A et al (2006). Longitudinal mapping of cortical thickness and clinical outcome in children and ado lescents with attention-deficit/hyperactivity disorder. Arch Gen Psychiatry 63: 540-549.
151. Sheridan MA, Fox NA, Zeanah CH, McLaughlin KA, Nelson CA (2012). Variation in neural development as a result of e xposure to institutionalization early in childhood. Proc Natl Acad Sci USA 109: 12927-12932.
152. Sheridan MA, McLaughlin KA (2014). Dimensions of early experience and neural development: Deprivation and threat. Manuscript under Editorial Review.
153. Shields A, Cicchetti D (2001). Parental maltreatment and emotion dysregulation as risk factors for bullying and victimization in middle childhood. J Clin Child Psychol 30: 349-363.
154. Shonkoff JP, Garner AS (2012). The lifelong effects of early childhood adversity and toxic stress. Pediatrics 129: E232-e246.
155. Singer MJ, Humphreys KL, Lee SS (2012). Coping self-efficacy mediates the association between child abuse and ADHD in adulthood. J Atten Disord print copy in press (originally published online 29 November 2012, at http://jad.sagepub.com/content/early/2012/11/29/1087054712465337/
156. Slopen N, McLaughlin KA, Fox NA, Zeanah CH, Nelson CA (2012). Alterations in neural processing and psychopathology in children raised in institutions. Arch Gen Psychiatry 69: 1022-1030.
157. Smith DK, Johnson AB, Pears KC, Fisher PA, DeGarmo DS (2007). Child maltreatment and foster care: Unpacking the effects of prenatal and postnatal parental substan ce use. Child Maltreat 12: 150-160.
158. Smyke AT, Dumitrescu A, Zeanah CH (2002). Attachment disturbances in young children. I: The continuum of caretaking casualty. J Am Acad Child Adolesc Psychiatry 41: 972-982.
159. Smyke AT, Koga SF, Johnson DE, Fox NA, Marshall PJ, Nelson CA et al (2007). The caregiving context in institution-reared and family-reared infants and toddlers in Romania. J Ch ild Psychol Psychiatry 48: 210-218.
160. Snyder SM, Hall JR (2006). A meta-analysis of quantitative EEG power associated with attention-deficit hyperactivity disorder. J Clin Neurophysiol 23: 440-455.
161. Soares I, Belsky J, Mesquita AR, Osorio A, Sampaio A (2013). Why do only some institutionalized children become indiscriminately friendly? Insights from the study of Williams Syndrome. Child Dev Perspect 7: 187-192.
162. Sonuga-Barke EJS, Beckett C, Kreppner J, Castle J, Colvert E, Stevens S et al (2008). Is sub-nutrition necessary for a poor outcome following early institutional deprivation? Dev Med Child Neurol 50: 664-671.
163. Spitz RA (1945). Hospitalism; an inquiry into the genesis of psychiatric conditions in early childhood. Psychoanal Study Child 1: 53-74.
164. Sroufe La (1983). Infant-caregi ver attachment and patterns of adaptation in preschool: The roots of maladaptation and competence. Dev Policy Concern Child with Spec Needs (Minnesota Symp Child Psychol 16: 41-83.
165. Stevens SE, Sonuga-Barke EJS, Kreppner JM, Beckett C, Castle J, Colvert E et al (2008). Inattention/overactivity following early severe institutional deprivation: Presentation and associations in early adolescence. J Abnorm Child Psychol 36: 385-398.
166. Stouthamer-Loeber M, Loeber R, Homish DL, Wei E (2001). Maltreatment of boys and the development of disruptive and delinquent behavior. Dev Psychopathol 13: 941-955.
167. Suliman S, Mkabile SG, Fincham DS, Ahmed R, Stein DJ, Seedat S (2009). Cumulative effect of multiple trauma on symptoms of posttraumatic stress disorder, anxiety, and depression in adolescents. Compr Psychiatry 50: 121-127.
168. Tarullo AR Garvin MC Gunnar MR 2011 Atypical EEG power correlates with indiscriminately friendly behavior in internationally adopted children Dev Psychol 47 417-431.
169. Thornberry TP, Ireland T O, Smith CA (2001). The importance of timing: The varying impact of childhood and adolescent maltreatment on multiple problem outcomes. Dev Psychopathol 13: 957-979.
170. Tibu F, Humphreys KL, Fox NA, Ne lson CA, Zeanah CA (2014). Psychopathology in young children in two types of foster care following institutional rearing. Infant Ment Health J 35: 123-131.
171. Tottenham N, Hare TA, Quinn BT, McCarry TW, Nurse M, Gilhooly T et al (2010). Prolonged institutional rearing is associated with atypically large amygdala volume and difficulties in emotion regulation. Dev Sci 13: 46-61.
172. Trickey D, Siddaway AP, Meiser-Stedman R, Serpell L, Field AP (2012). A metaanalysis of risk factors for post-traumatic stress disorder in children and adolescents. Clin Psychol Rev 32: 122-138.
173. Tronick EZ (1989). Emotions and emotional communication in infants. Am Psychol 44: 112-119.
174. Van Der Kolk BA (2003). Psychological Trauma. American Psychiatric Press.
175. Van Der K olk BA (2005). Developmental trauma disorder. Psychiatr Ann 35: 401-408.
176. Vanderwert RE, Marshall PJ, Nelson CA, Zeanah CH, Fox NA (2010). Timing of intervention affects brain electrical activit y in children exposed to severe psychosocial neglect. PLoS One 5: E11415.
177. Viding E, Frick PJ, Plomin R (2007). Aetiology of the relationship between callousunemotional traits and conduct problems in childhood. Br J Psychiatry 49: S33-s38.
178. Webb E (2013). Poverty, maltreatment and attention deficit hyperactivity disorder. Arch Dis Child 98: 397-400.
179. White MG, Bogdan R, Fisher PM, Mun? oz KE, Williamson DE, Hariri AR (2012). FKBP5 and emotional neglect interact to predict individual differences in amygdala reactivity. Genes Brain Behav 11: 869-878.
180. Widom CS (1998). Childhood victimization: Early adversity and subsequent psychopathology. In: Dohrenwend BP (ed). Adversity, Stress, and Psychopathology. Oxford University Press, pp 81-95.
181. Widom CS (1999). Posttraumatic stress disorder in abused and neglected children grown up. Am J Psychiatry 156: 1223-1229.
182. Wiik KL, Loman MM, Van Ryzin MJ, Armstrong JM, Essex MJ, Pollak SD et al (2011). Behavioral and emotional symptoms of post-institutionalized children in middle childhood. J Child Psychol Psychiatry 52: 56-63.
183. Wilson KR, Hansen DJ, Li M (2011). The traumatic stress response in child maltreatment and resultant neuropsychological effects. Aggress Violent Behav 16: 87-97.
184. Wismer Fries AB, Shi rtcliff EA, Pollak SD (2008). Neuroendocrine dysregulation following early social deprivation in children. Dev Psychobiol 50: 588-599.
185. Wismer Fries AB, Ziegler TE, Kurian JR, Jacoris S, Pollak S D (2005). Early experience in humans is associated with changes in neuropeptides critical for regulating social behavior. Proc Natl Acad Sci USA 102: 17237-17240.
186. Woon FL, Hedges DW (2008). Hippocampal and amygdala volumes in children and adults with childhood maltreatment-related posttraumatic stress disorder: A meta-analysis. Hippocampus 18: 729-736.
187. Wozniak J, Crawford MH, Biederman J, Faraone S V, Spe ncer TJ, Taylor A et al (1999). Antecedents and complications of trauma in boys with ADHD: Findings from a longitudinal study. J Am Acad Child Adolesc Psychiatry 38: 48-55.
188. Zeanah CH (2014). Psychopath ology at age 12 years in children who experienced institutional rearing. 14th World Congrress of the World Association for Infant Mental Health.
189. Zeanah C.H. Egger HL Smyke AT Nelson C.A. Fox N.A. Marshall PJ et al 2009 Institutional rearing and psychiatric disorders in Romanian preschool children Am J Psychiatry 166 777-785.
190. Zeanah CH, Gleason MM (in press). Attachment disorders in early childhood: Clinical presentation, causes, correlates and treatment. J Child Psychol Psychiatry.
191. Zeanah CH, Nelson CA, Fox NA, Smyke AT, Marshall P, Parker SW et al (2003). Designing research to study the effects of institut ionalization on brain and behavioral development: The Bucharest Early Intervention Project. Dev Psychopathol 15: 885-907.
192. Zeanah CH, Scheeringa M, Boris NW, Heller SS, Smyke AT, Trapani J (2004). Reactive attachment disorder in maltreated toddlers. Child Abus Negl 28: 877-888.
193. Zeanah CH, Smyke AT, Dumitrescu A (2002). Attachment disturbances in young children. II: Indiscriminate behavior and insti tutional care. J Am Acad Child Adolesc Psychiatry 41: 983-989.
194. Zeanah CH, Smyke AT, Koga SF, Carlson E (2005). Attachment in institutionalized and community children in Romania. Child Dev 76: 1015-1028.