-
1
-
-
84906852294
-
Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but nonapoptotic caspase-8 is required for inflammasome priming
-
Allam, R., Lawlor, K.E., Yu, E.C., Mildenhall, A.L., Moujalled, D.M., Lewis, R.S., Ke, F., Mason, K.D., White, M.J., Stacey, K.J., Strasser, A., O'Reilly, L.A., Alexander, W., Kile, B.T., Vaux, D.L., and Vince, J.E. (2014). Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but nonapoptotic caspase-8 is required for inflammasome priming. EMBO Rep 9, 982-990.
-
(2014)
EMBO Rep
, vol.9
, pp. 982-990
-
-
Allam, R.1
Lawlor, K.E.2
Yu, E.C.3
Mildenhall, A.L.4
Moujalled, D.M.5
Lewis, R.S.6
Ke, F.7
Mason, K.D.8
White, M.J.9
Stacey, K.J.10
Strasser, A.11
O'Reilly, L.A.12
Alexander, W.13
Kile, B.T.14
Vaux, D.L.15
Vince, J.E.16
-
2
-
-
84888140819
-
Autophagy in inflammation, infection, neurodegeneration and cancer
-
Arroyo, D.S., Gaviglio, E.A., Peralta Ramos, J.M., Bussi, C., Rodriguez-Galan, M.C., and Iribarren, P. (2014). Autophagy in inflammation, infection, neurodegeneration and cancer. Int Immunopharmacol 18, 55-65.
-
(2014)
Int Immunopharmacol
, vol.18
, pp. 55-65
-
-
Arroyo, D.S.1
Gaviglio, E.A.2
Peralta Ramos, J.M.3
Bussi, C.4
Rodriguez-Galan, M.C.5
Iribarren, P.6
-
3
-
-
84874596968
-
Inflammasome components coordinate autophagy and pyroptosis as macrophage responses to infection
-
Byrne, B.G., Dubuisson, J.-F.F., Joshi, A.D., Persson, J.J., and Swanson, M.S. (2013). Inflammasome components coordinate autophagy and pyroptosis as macrophage responses to infection. MBio 4, e00620-12.
-
(2013)
MBio
, vol.4
, pp. e00620-e00712
-
-
Byrne, B.G.1
Dubuisson, J.-F.F.2
Joshi, A.D.3
Persson, J.J.4
Swanson, M.S.5
-
4
-
-
84907898151
-
Autophagy in microglia degrades extracellular bamyloid fibrils and regulates the NLRP3 inflammasome
-
Cho, M.-H., Cho, K., Kang, H.-J., Jeon, E.-Y., Kim, H.-S., et al. (2014). Autophagy in microglia degrades extracellular bamyloid fibrils and regulates the NLRP3 inflammasome. Autophagy 10, 1-15.
-
(2014)
Autophagy
, vol.10
, pp. 1-15
-
-
Cho, M.-H.1
Cho, K.2
Kang, H.-J.3
Jeon, E.-Y.4
Kim, H.-S.5
-
5
-
-
84926642760
-
Natural compounds and aging: Between autophagy and inflammasome
-
Chuang, S.-Y., Lin, C.-H., and Fang, J.-Y. (2014). Natural compounds and aging: between autophagy and inflammasome. Biomed Res Int 2014, 297293.
-
(2014)
Biomed Res Int
, vol.2014
, pp. 297293
-
-
Chuang, S.-Y.1
Lin, C.-H.2
Fang, J.-Y.3
-
6
-
-
84885077685
-
TLR-induced PAI-2 expression suppresses IL-1b processing via increasing autophagy and NLRP3 degradation
-
Chuang, S.-Y., Yang, C.-H., Chou, C.-C., Chiang, Y.-P., Chuang, T.-H., and Hsu, L.-C. (2013). TLR-induced PAI-2 expression suppresses IL-1b processing via increasing autophagy and NLRP3 degradation. Proc Natl Acad Sci U S A 110, 16079-16084.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 16079-16084
-
-
Chuang, S.-Y.1
Yang, C.-H.2
Chou, C.-C.3
Chiang, Y.-P.4
Chuang, T.-H.5
Hsu, L.-C.6
-
7
-
-
79953046719
-
The inflammasome NLRs in immunity, inflammation, and associated diseases
-
Davis, B.K., Wen, H., and Ting, J.P.-Y. (2011). The inflammasome NLRs in immunity, inflammation, and associated diseases. Annu Rev Immunol 29, 707-735.
-
(2011)
Annu Rev Immunol
, vol.29
, pp. 707-735
-
-
Davis, B.K.1
Wen, H.2
Ting, J.P.-Y.3
-
8
-
-
84862888230
-
Autophagy: An emerging immunological paradigm
-
Deretic, V. (2012). Autophagy: an emerging immunological paradigm. J Immunol 189, 15-20.
-
(2012)
J Immunol
, vol.189
, pp. 15-20
-
-
Deretic, V.1
-
9
-
-
84886797274
-
Autophagy in infection, inflammation and immunity
-
Deretic, V., Saitoh, T., and Akira, S. (2013). Autophagy in infection, inflammation and immunity. Nat Rev Immunol 13, 722-737.
-
(2013)
Nat Rev Immunol
, vol.13
, pp. 722-737
-
-
Deretic, V.1
Saitoh, T.2
Akira, S.3
-
10
-
-
84907356094
-
LOX-1, mtDNA damage and NLRP3 inflammasome activation in macrophages: Implications in atherogenesis
-
Ding, Z., Liu, S., Wang, X., Dai, Y., Khaidakov, M., et al. (2014). LOX-1, mtDNA damage and NLRP3 inflammasome activation in macrophages: implications in atherogenesis. Cardiovasc Res 103, 501-526.
-
(2014)
Cardiovasc Res
, vol.103
, pp. 501-526
-
-
Ding, Z.1
Liu, S.2
Wang, X.3
Dai, Y.4
Khaidakov, M.5
-
11
-
-
82455210868
-
Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1b
-
Dupont, N., Jiang, S., Pilli, M., Ornatowski, W., Bhattacharya, D., and Deretic, V. (2011). Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1b. EMBO J 30, 4701-4711.
-
(2011)
EMBO J
, vol.30
, pp. 4701-4711
-
-
Dupont, N.1
Jiang, S.2
Pilli, M.3
Ornatowski, W.4
Bhattacharya, D.5
Deretic, V.6
-
12
-
-
84858677223
-
Sensing and reacting to microbes through the inflammasomes
-
Franchi, L., Muñoz-Planillo, R., and Núñez, G. (2012). Sensing and reacting to microbes through the inflammasomes. Nat Immunol 13, 325-332.
-
(2012)
Nat Immunol
, vol.13
, pp. 325-332
-
-
Franchi, L.1
Muñoz-Planillo, R.2
Núñez, G.3
-
13
-
-
58049200723
-
Function of Nod-like receptors in microbial recognition and host defense
-
Franchi, L., Warner, N., Viani, K., and Nuñez, G. (2009). Function of Nod-like receptors in microbial recognition and host defense. Immunol Rev 227, 106-128.
-
(2009)
Immunol Rev
, vol.227
, pp. 106-128
-
-
Franchi, L.1
Warner, N.2
Viani, K.3
Nuñez, G.4
-
14
-
-
84889985155
-
Involvement of interleukin-1b in the autophagic process of microglia: Relevance to Alzheimer's disease
-
François, A., Terro, F., Janet, T., Rioux Bilan, A., Paccalin, M., and Page, G. (2013). Involvement of interleukin-1b in the autophagic process of microglia: relevance to Alzheimer's disease. J Neuroinflammation 10, 151.
-
(2013)
J Neuroinflammation
, vol.10
, pp. 151
-
-
François, A.1
Terro, F.2
Janet, T.3
Rioux Bilan, A.4
Paccalin, M.5
Page, G.6
-
15
-
-
84903599695
-
Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer
-
Guo, W., Sun, Y., Liu, W., Wu, X., Guo, L., et al. (2014). Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer. Autophagy 10, 972-985.
-
(2014)
Autophagy
, vol.10
, pp. 972-985
-
-
Guo, W.1
Sun, Y.2
Liu, W.3
Wu, X.4
Guo, L.5
-
16
-
-
84926011028
-
Reactive oxygen species at the crossroads of inflammasome and inflammation
-
Harijith, A., Ebenezer, D.L., and Natarajan, V. (2014). Reactive oxygen species at the crossroads of inflammasome and inflammation. Front Physiol 5, 352.
-
(2014)
Front Physiol
, vol.5
, pp. 352
-
-
Harijith, A.1
Ebenezer, D.L.2
Natarajan, V.3
-
17
-
-
79953176280
-
Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation
-
Harris, J., Hartman, M., Roche, C., Zeng, S.G., O'Shea, A., et al. (2011). Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation. J Biol Chem 286, 9587-9597.
-
(2011)
J Biol Chem
, vol.286
, pp. 9587-9597
-
-
Harris, J.1
Hartman, M.2
Roche, C.3
Zeng, S.G.4
O'Shea, A.5
-
18
-
-
84856002234
-
Autophagy: Cellular defense to excessive inflammation
-
Jo, E.K., Shin, D.M., and Choi, A.M.K. (2012). Autophagy: cellular defense to excessive inflammation. Microbes Infect 14, 119-125.
-
(2012)
Microbes Infect
, vol.14
, pp. 119-125
-
-
Jo, E.K.1
Shin, D.M.2
Choi, A.M.K.3
-
19
-
-
78751672975
-
Autophagy in immunity and inflammation
-
Levine, B., Mizushima, N., and Virgin, H.W. (2011). Autophagy in immunity and inflammation. Nature 469, 323-335.
-
(2011)
Nature
, vol.469
, pp. 323-335
-
-
Levine, B.1
Mizushima, N.2
Virgin, H.W.3
-
20
-
-
84911390954
-
Endoplasmic reticulum stress is involved in the connection between inflammation and autophagy in type 2 diabetes
-
Liu, H., Cao, M., Wang, Y., Li, L., Zhu, L., et al. (2015). Endoplasmic reticulum stress is involved in the connection between inflammation and autophagy in type 2 diabetes. Gen Comp Endocrinol 210, 124-129.
-
(2015)
Gen Comp Endocrinol
, vol.210
, pp. 124-129
-
-
Liu, H.1
Cao, M.2
Wang, Y.3
Li, L.4
Zhu, L.5
-
21
-
-
84907218485
-
HMGB1-DNA complex-induced autophagy limits AIM2 inflammasome activation through RAGE
-
Liu, L., Yang, M., Kang, R., Dai, Y., Yu, Y., et al. (2014). HMGB1-DNA complex-induced autophagy limits AIM2 inflammasome activation through RAGE. Biochem Biophys Res Commun 450, 851-856.
-
(2014)
Biochem Biophys Res Commun
, vol.450
, pp. 851-856
-
-
Liu, L.1
Yang, M.2
Kang, R.3
Dai, Y.4
Yu, Y.5
-
22
-
-
84876685141
-
Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection
-
Lupfer, C., Thomas, P.G., Anand, P.K., Vogel, P., Milasta, S., et al. (2013). Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection. Nat Immunol 14, 480-488.
-
(2013)
Nat Immunol
, vol.14
, pp. 480-488
-
-
Lupfer, C.1
Thomas, P.G.2
Anand, P.K.3
Vogel, P.4
Milasta, S.5
-
23
-
-
80052626087
-
The NLRP3 inflammasome in health and disease: The good, the bad and the ugly
-
Menu, P., and Vince, J.E. (2011). The NLRP3 inflammasome in health and disease: the good, the bad and the ugly. Clin Exp Immunol 166, 1-15.
-
(2011)
Clin Exp Immunol
, vol.166
, pp. 1-15
-
-
Menu, P.1
Vince, J.E.2
-
24
-
-
66449088641
-
Pathogen recognition and inflammatory signaling in innate immune defenses
-
Mogensen, T.H. (2009). Pathogen recognition and inflammatory signaling in innate immune defenses. Clin Microbiol Rev 22, 240-273.
-
(2009)
Clin Microbiol Rev
, vol.22
, pp. 240-273
-
-
Mogensen, T.H.1
-
25
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
Nakahira, K., Haspel, J.A., Rathinam, V.A.K., Lee, S.-J., Dolinay, T., et al. (2011). Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol 12, 222-230.
-
(2011)
Nat Immunol
, vol.12
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.K.3
Lee, S.-J.4
Dolinay, T.5
-
26
-
-
0035902802
-
Chronic immune activation and inflammation as the cause of malignancy
-
O'Byrne, K.J., and Dalgleish, A.G. (2001). Chronic immune activation and inflammation as the cause of malignancy. Br J Cancer 85, 473-483.
-
(2001)
Br J Cancer
, vol.85
, pp. 473-483
-
-
O'Byrne, K.J.1
Dalgleish, A.G.2
-
27
-
-
84902141285
-
Dectin-1 pathway activates robust autophagy-dependent unconventional protein secretion in human macrophages
-
Ohman, T., Teirila?, L., Lahesmaa-Korpinen, A.-M., Cypryk, W., Veckman, V., et al. (2014). Dectin-1 pathway activates robust autophagy-dependent unconventional protein secretion in human macrophages. J Immunol 192, 5952-5962.
-
(2014)
J Immunol
, vol.192
, pp. 5952-5962
-
-
Ohman, T.1
Teirila, L.2
Lahesmaa-Korpinen, A.-M.3
Cypryk, W.4
Veckman, V.5
-
28
-
-
84907828161
-
Decline in cellular clearance systems induces inflammasome signaling in human ARPE-19 cells
-
Piippo, N., Korkmaz, A., Hytti, M., Kinnunen, K., Salminen, A., et al. (2014). Decline in cellular clearance systems induces inflammasome signaling in human ARPE-19 cells. Biochim Biophys Acta 1843, 3038-3046.
-
(2014)
Biochim Biophys Acta
, vol.1843
, pp. 3038-3046
-
-
Piippo, N.1
Korkmaz, A.2
Hytti, M.3
Kinnunen, K.4
Salminen, A.5
-
29
-
-
84859448447
-
Autophagy links inflammasomes to atherosclerotic progression
-
Razani, B., Feng, C., Coleman, T., Emanuel, R., Wen, H., et al. (2012). Autophagy links inflammasomes to atherosclerotic progression. Cell Metab 15, 534-544.
-
(2012)
Cell Metab
, vol.15
, pp. 534-544
-
-
Razani, B.1
Feng, C.2
Coleman, T.3
Emanuel, R.4
Wen, H.5
-
30
-
-
84878562770
-
Autophagic processes in yeast: Mechanism, machinery and regulation
-
Reggiori, F., and Klionsky, D.J. (2013). Autophagic processes in yeast: mechanism, machinery and regulation. Genetics 194, 341-361.
-
(2013)
Genetics
, vol.194
, pp. 341-361
-
-
Reggiori, F.1
Klionsky, D.J.2
-
31
-
-
56249090667
-
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
-
Saitoh, T., Fujita, N., Jang, M.H., Uematsu, S., Yang, B.-G., et al. (2008). Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature 456, 264-268.
-
(2008)
Nature
, vol.456
, pp. 264-268
-
-
Saitoh, T.1
Fujita, N.2
Jang, M.H.3
Uematsu, S.4
Yang, B.-G.5
-
32
-
-
84873267192
-
Beclin 1 interactome controls the crosstalk between apoptosis, autophagy and inflammasome activation: Impact on the aging process
-
Salminen, A., Kaarniranta, K., and Kauppinen, A. (2013). Beclin 1 interactome controls the crosstalk between apoptosis, autophagy and inflammasome activation: impact on the aging process. Ageing Res Rev 12, 520-534.
-
(2013)
Ageing Res Rev
, vol.12
, pp. 520-534
-
-
Salminen, A.1
Kaarniranta, K.2
Kauppinen, A.3
-
33
-
-
84905656869
-
NOD-like receptors: Master regulators of inflammation and cancer
-
Saxena, M., and Yeretssian, G. (2014). NOD-like receptors: master regulators of inflammation and cancer. Front Immunol 5, 327.
-
(2014)
Front Immunol
, vol.5
, pp. 327
-
-
Saxena, M.1
Yeretssian, G.2
-
34
-
-
84857195479
-
Activation of autophagy by inflammatory signals limits IL-1b production by targeting ubiquitinated inflammasomes for destruction
-
Shi, C.-S., Shenderov, K., Huang, N.-N., Kabat, J., Abu-Asab, M., et al. (2012). Activation of autophagy by inflammatory signals limits IL-1b production by targeting ubiquitinated inflammasomes for destruction. Nat Immunol 13, 255-263.
-
(2012)
Nat Immunol
, vol.13
, pp. 255-263
-
-
Shi, C.-S.1
Shenderov, K.2
Huang, N.-N.3
Kabat, J.4
Abu-Asab, M.5
-
35
-
-
84890364356
-
Inflammasome activation by altered proteostasis
-
Shin, J.N., Fattah, E.A., Bhattacharya, A., Ko, S., and Eissa, N.T. (2013). Inflammasome activation by altered proteostasis. J Biol Chem 288, 35886-35895.
-
(2013)
J Biol Chem
, vol.288
, pp. 35886-35895
-
-
Shin, J.N.1
Fattah, E.A.2
Bhattacharya, A.3
Ko, S.4
Eissa, N.T.5
-
36
-
-
84878405540
-
Caspase 1 activation is protective against hepatocyte cell death by up-regulating beclin 1 protein and mitochondrial autophagy in the setting of redox stress
-
Sun, Q., Gao, W., Loughran, P., Shapiro, R., Fan, J., et al. (2013). Caspase 1 activation is protective against hepatocyte cell death by up-regulating beclin 1 protein and mitochondrial autophagy in the setting of redox stress. J Biol Chem 288, 15947-15958.
-
(2013)
J Biol Chem
, vol.288
, pp. 15947-15958
-
-
Sun, Q.1
Gao, W.2
Loughran, P.3
Shapiro, R.4
Fan, J.5
-
37
-
-
38049086105
-
A role for Nod-like receptors in autophagy induced by Shigella infection
-
Suzuki, T., and Núñez, G. (2008). A role for Nod-like receptors in autophagy induced by Shigella infection. Autophagy 4, 73-75.
-
(2008)
Autophagy
, vol.4
, pp. 73-75
-
-
Suzuki, T.1
Núñez, G.2
-
38
-
-
84896867382
-
The inflammasome and its regulation
-
Tsuchiya, K., and Hara, H. (2014). The inflammasome and its regulation. Crit Rev Immunol 34, 41-80.
-
(2014)
Crit Rev Immunol
, vol.34
, pp. 41-80
-
-
Tsuchiya, K.1
Hara, H.2
-
39
-
-
84894481149
-
Defects in mitochondrial clearance predispose human monocytes to interleukin-1b hypersecretion
-
Van Der Burgh, R., Nijhuis, L., Pervolaraki, K., Compeer, E.B., Jongeneel, L.H., et al. (2014). Defects in mitochondrial clearance predispose human monocytes to interleukin-1b hypersecretion. J Biol Chem 289, 5000-5012.
-
(2014)
J Biol Chem
, vol.289
, pp. 5000-5012
-
-
Van Der Burgh, R.1
Nijhuis, L.2
Pervolaraki, K.3
Compeer, E.B.4
Jongeneel, L.H.5
-
40
-
-
84908053092
-
The microtubule-associated protein EB1 links AIM2 inflammasomes with autophagy-dependent secretion
-
Wang, L.-J., Huang, H.-Y., Huang, M.-P., Liou, W., Chang, Y.-T., et al. (2014). The microtubule-associated protein EB1 links AIM2 inflammasomes with autophagy-dependent secretion. J Biol Chem 289, 29322-29333.
-
(2014)
J Biol Chem
, vol.289
, pp. 29322-29333
-
-
Wang, L.-J.1
Huang, H.-Y.2
Huang, M.-P.3
Liou, W.4
Chang, Y.-T.5
-
41
-
-
84877331888
-
Autophagy regulates inflammation following oxidative injury in diabetes
-
Wang, Y., Li, Y.B., Yin, J.J., Wang, Y., Zhu, L.B., et al. (2013). Autophagy regulates inflammation following oxidative injury in diabetes. Autophagy 9, 272-277.
-
(2013)
Autophagy
, vol.9
, pp. 272-277
-
-
Wang, Y.1
Li, Y.B.2
Yin, J.J.3
Wang, Y.4
Zhu, L.B.5
-
42
-
-
84900420410
-
Crosstalk between autophagy and inflammasomes
-
Yuk, J.-M.M., and Jo, E.-K.K. (2013). Crosstalk between autophagy and inflammasomes. Mol Cells 36, 393-399.
-
(2013)
Mol Cells
, vol.36
, pp. 393-399
-
-
Yuk, J.-M.M.1
Jo, E.-K.K.2
-
43
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
Zhou, R., Yazdi, A.S., Menu, P., and Tschopp, J. (2011). A role for mitochondria in NLRP3 inflammasome activation. Nature 469, 221-225.
-
(2011)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
|