메뉴 건너뛰기




Volumn 55, Issue 2-3, 2010, Pages 390-395

Patulin-induced oxidative DNA damage and p53 modulation in HepG2 cells

Author keywords

Glutathione; HepG2 cells; Oxidative DNA damage; P53; Patulin; Single cell gel electrophoresis

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; BUTHIONINE SULFOXIMINE; DICHLORODIHYDROFLUORESCEIN DIACETATE; DNA; GLUTATHIONE; PATULIN; PHTHALALDEHYDE; PROTEIN P53; REACTIVE OXYGEN METABOLITE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

EID: 72749095740     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2009.08.019     Document Type: Article
Times cited : (52)

References (38)
  • 1
    • 0018718742 scopus 로고
    • Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line
    • Aden D.P., Fogel A., Plotkin S., Damjanov I., and Knowles B.B. Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line. Nature 282 (1979) 615-616
    • (1979) Nature , vol.282 , pp. 615-616
    • Aden, D.P.1    Fogel, A.2    Plotkin, S.3    Damjanov, I.4    Knowles, B.B.5
  • 2
    • 0034067139 scopus 로고    scopus 로고
    • Induction of micronuclei and chromosomal aberrations by the mycotoxin patulin in mammalian cells: role of ascorbic acid as a modulatorof patulin clastogenicity
    • Alves I., Oliveira N.G., Laires A., Rodrigues A.S., and Rueff J. Induction of micronuclei and chromosomal aberrations by the mycotoxin patulin in mammalian cells: role of ascorbic acid as a modulatorof patulin clastogenicity. Mutagenesis 15 (2000) 229-234
    • (2000) Mutagenesis , vol.15 , pp. 229-234
    • Alves, I.1    Oliveira, N.G.2    Laires, A.3    Rodrigues, A.S.4    Rueff, J.5
  • 3
    • 26844473978 scopus 로고    scopus 로고
    • Kinetic analysis of the chronology of patulin- and gossypol-induced cytotoxicity in vitro
    • Barhoumi R., and Burghardt R.C. Kinetic analysis of the chronology of patulin- and gossypol-induced cytotoxicity in vitro. Fundam. Appl. Toxicol 30 (1996) 290-297
    • (1996) Fundam. Appl. Toxicol , vol.30 , pp. 290-297
    • Barhoumi, R.1    Burghardt, R.C.2
  • 4
    • 0038424492 scopus 로고    scopus 로고
    • Council of Agricultural Science and Technology, Task force rep. no. 139, CAST, Ames, IA
    • CAST. Mycotoxins: risks in plant, animal, and human systems. Council of Agricultural Science and Technology, Task force rep. no. 139 (2003), CAST, Ames, IA
    • (2003) Mycotoxins: risks in plant, animal, and human systems
    • CAST1
  • 5
    • 2942572700 scopus 로고    scopus 로고
    • Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean?
    • Halliwell B., and Whiteman M. Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean?. Br. J. Pharmacol 142 (2004) 231-255
    • (2004) Br. J. Pharmacol , vol.142 , pp. 231-255
    • Halliwell, B.1    Whiteman, M.2
  • 6
    • 0017064979 scopus 로고
    • A fluorometric method for determination of oxidized and reduced glutathione in tissues
    • Hissin P.J., and Hilf R. A fluorometric method for determination of oxidized and reduced glutathione in tissues. Anal. Biochem 74 (1976) 214-226
    • (1976) Anal. Biochem , vol.74 , pp. 214-226
    • Hissin, P.J.1    Hilf, R.2
  • 8
    • 0031469841 scopus 로고    scopus 로고
    • Analysis of a form of oxidative DNA damage, 8-hydroxy- 2-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis
    • Kasai H. Analysis of a form of oxidative DNA damage, 8-hydroxy- 2-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis. Mutat. Res. 387 (1997) 147-163
    • (1997) Mutat. Res. , vol.387 , pp. 147-163
    • Kasai, H.1
  • 9
    • 0021769722 scopus 로고
    • Hydroxylation of deoxyguanosine at the C8 position by ascorbic acid and other reducing agents
    • Kasai H., and Nishimura S. Hydroxylation of deoxyguanosine at the C8 position by ascorbic acid and other reducing agents. Nucleic Acids Res. 12 (1984) 2137-2145
    • (1984) Nucleic Acids Res. , vol.12 , pp. 2137-2145
    • Kasai, H.1    Nishimura, S.2
  • 11
    • 0019332750 scopus 로고
    • Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen
    • Knowles B.B., Howe C.C., and Aden D.P. Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. Science 209 (1980) 497-499
    • (1980) Science , vol.209 , pp. 497-499
    • Knowles, B.B.1    Howe, C.C.2    Aden, D.P.3
  • 12
    • 0018195287 scopus 로고
    • The glutathione status of cells
    • Kosower N.S., and Kosower E.M. The glutathione status of cells. Int. Rev. Cytol 54 (1978) 109-160
    • (1978) Int. Rev. Cytol , vol.54 , pp. 109-160
    • Kosower, N.S.1    Kosower, E.M.2
  • 14
    • 0028848633 scopus 로고
    • Mutagenicity of a unique 8-oxoguanine in a human Ha-ras sequence in mammalian cells
    • Lepage F., Margot A., Grollman A.P., Sarasin A., and Gentil A. Mutagenicity of a unique 8-oxoguanine in a human Ha-ras sequence in mammalian cells. Carcinogenesis 16 (1995) 2779-2784
    • (1995) Carcinogenesis , vol.16 , pp. 2779-2784
    • Lepage, F.1    Margot, A.2    Grollman, A.P.3    Sarasin, A.4    Gentil, A.5
  • 16
    • 0043234938 scopus 로고    scopus 로고
    • Evaluation of genotoxic risk and oxidative DNA damage in mammalian cells exposed to mycotoxins, patulin and citrinin
    • Liu B.H., Yu F.Y., Wu T.S., Li S.Y., Su M.C., Wang M.C., and Shih S.M. Evaluation of genotoxic risk and oxidative DNA damage in mammalian cells exposed to mycotoxins, patulin and citrinin. Toxicol. Appl. Pharmacol 191 (2003) 255-263
    • (2003) Toxicol. Appl. Pharmacol , vol.191 , pp. 255-263
    • Liu, B.H.1    Yu, F.Y.2    Wu, T.S.3    Li, S.Y.4    Su, M.C.5    Wang, M.C.6    Shih, S.M.7
  • 17
    • 0034039040 scopus 로고    scopus 로고
    • Dial 9-1-1 for p53: mechanisms of p53 activation by cellular stress
    • Ljungman M. Dial 9-1-1 for p53: mechanisms of p53 activation by cellular stress. Neoplasia 2 (2000) 209-225
    • (2000) Neoplasia , vol.2 , pp. 209-225
    • Ljungman, M.1
  • 18
    • 0027074364 scopus 로고
    • Oxidative DNA damage estimated by 8-hydroxydeoxyguanosine excretion in humans: influence of smoking, gender and body mass index
    • Loft S., Vistisen K., Ewertz M., Tjnneland A., Overvad K., and Poulsen H.E. Oxidative DNA damage estimated by 8-hydroxydeoxyguanosine excretion in humans: influence of smoking, gender and body mass index. Carcinogenesis 13 (1992) 2241-2247
    • (1992) Carcinogenesis , vol.13 , pp. 2241-2247
    • Loft, S.1    Vistisen, K.2    Ewertz, M.3    Tjnneland, A.4    Overvad, K.5    Poulsen, H.E.6
  • 19
    • 31144468764 scopus 로고    scopus 로고
    • Cisplatin-induced hepatotoxicity is enhanced by elevated expression of cytochrome P450 2E1
    • Lu Y., and Cederbaum A.I. Cisplatin-induced hepatotoxicity is enhanced by elevated expression of cytochrome P450 2E1. Toxicol. Sci. 89 (2006) 515-523
    • (2006) Toxicol. Sci. , vol.89 , pp. 515-523
    • Lu, Y.1    Cederbaum, A.I.2
  • 20
    • 2342483759 scopus 로고    scopus 로고
    • Use of a human-derived liver cell line for the detection of cytoprotective, antigenotoxic and cogenotoxic agents
    • Mersch-Sundermann V., Knasmuller S., Wu X.J., Darroudi F., and Kassie F. Use of a human-derived liver cell line for the detection of cytoprotective, antigenotoxic and cogenotoxic agents. Toxicology 198 (2004) 329-340
    • (2004) Toxicology , vol.198 , pp. 329-340
    • Mersch-Sundermann, V.1    Knasmuller, S.2    Wu, X.J.3    Darroudi, F.4    Kassie, F.5
  • 21
    • 0027215203 scopus 로고
    • Mutation in the mutY gene of Escherichia coli enhances the frequency of targeted GC 3 TA transversions induced by a single 8-oxoguanine residue in single-stranded DNA
    • Moriya M., and Grollman A.P. Mutation in the mutY gene of Escherichia coli enhances the frequency of targeted GC 3 TA transversions induced by a single 8-oxoguanine residue in single-stranded DNA. Mol. Gen. Genet. 239 (1993) 72-76
    • (1993) Mol. Gen. Genet. , vol.239 , pp. 72-76
    • Moriya, M.1    Grollman, A.P.2
  • 22
    • 0033579412 scopus 로고    scopus 로고
    • Regulation of the p53 tumor suppressor protein
    • Oren M. Regulation of the p53 tumor suppressor protein. J. Biol. Chem. 274 (1999) 36031-36034
    • (1999) J. Biol. Chem. , vol.274 , pp. 36031-36034
    • Oren, M.1
  • 23
    • 33749627734 scopus 로고    scopus 로고
    • Benzo[a]pyrene-induced DNA damage and p53 modulation in human hepatoma HepG2 cells for the identification of potential biomarkers for PAH monitoring and risk assessment
    • Park S.Y., Lee S.M., Ye S.K., Yoon S.H., Chung M.H., and Choi J. Benzo[a]pyrene-induced DNA damage and p53 modulation in human hepatoma HepG2 cells for the identification of potential biomarkers for PAH monitoring and risk assessment. Toxicol. Lett. 167 (2006) 27-33
    • (2006) Toxicol. Lett. , vol.167 , pp. 27-33
    • Park, S.Y.1    Lee, S.M.2    Ye, S.K.3    Yoon, S.H.4    Chung, M.H.5    Choi, J.6
  • 24
    • 0031927107 scopus 로고    scopus 로고
    • Aneuploidogenic and clastogenic potencial of the mycotoxins citrinin and patulin
    • Pfeiffer E., Groβ K., and Metzle rM. Aneuploidogenic and clastogenic potencial of the mycotoxins citrinin and patulin. Carcinogenesis 19 (1998) 1313-1318
    • (1998) Carcinogenesis , vol.19 , pp. 1313-1318
    • Pfeiffer, E.1    Groß, K.2    Metzle, rM.3
  • 25
    • 0025736665 scopus 로고
    • The mechanism of patulin's cytotoxicity and its antioxidant activity of indole tetramic acids
    • Riley R.T., and Showker J.L. The mechanism of patulin's cytotoxicity and its antioxidant activity of indole tetramic acids. Toxicol. Appl. Pharmacol 109 (1991) 108-126
    • (1991) Toxicol. Appl. Pharmacol , vol.109 , pp. 108-126
    • Riley, R.T.1    Showker, J.L.2
  • 26
    • 0036783335 scopus 로고    scopus 로고
    • Pharmacogenomics, regulation and signaling pathways of phase I and II drug metabolizing enzymes
    • Rushmore T.H., and Kong A.N. Pharmacogenomics, regulation and signaling pathways of phase I and II drug metabolizing enzymes. Curr Drug Metab 3 (2002) 481-490
    • (2002) Curr Drug Metab , vol.3 , pp. 481-490
    • Rushmore, T.H.1    Kong, A.N.2
  • 27
    • 0026544394 scopus 로고
    • The protective role of glutathione, cysteine and vitamin C against oxidative DNA damage induced in rat kidney by potassium bromate
    • Sai K., Umemura T., Takagi A., Hasegawa R., and Kurokawa Y. The protective role of glutathione, cysteine and vitamin C against oxidative DNA damage induced in rat kidney by potassium bromate. Jpn. J. Cancer Res. 83 1 (1992) 45-51
    • (1992) Jpn. J. Cancer Res. , vol.83 , Issue.1 , pp. 45-51
    • Sai, K.1    Umemura, T.2    Takagi, A.3    Hasegawa, R.4    Kurokawa, Y.5
  • 28
    • 14644408151 scopus 로고    scopus 로고
    • Mutagenicity of the mycotoxin patulin in cultured Chinese hamster V79 cells, and its modulation by intracellular glutathione
    • Schumacher D.M., Metzler M., and Lehmann L. Mutagenicity of the mycotoxin patulin in cultured Chinese hamster V79 cells, and its modulation by intracellular glutathione. Arch. Toxicol 79 (2005) 110-121
    • (2005) Arch. Toxicol , vol.79 , pp. 110-121
    • Schumacher, D.M.1    Metzler, M.2    Lehmann, L.3
  • 30
    • 0030968310 scopus 로고    scopus 로고
    • Microgel electrophoresis: sensitivity, mechanisms, and DNA electrostretching
    • Singh N.P., and Stephens R.E. Microgel electrophoresis: sensitivity, mechanisms, and DNA electrostretching. Mutat. Res. 383 (1997) 167-175
    • (1997) Mutat. Res. , vol.383 , pp. 167-175
    • Singh, N.P.1    Stephens, R.E.2
  • 31
    • 21144458092 scopus 로고    scopus 로고
    • Protective effects of panduratin A against oxidative damage of tertbutylhydroperoxide in human HepG2 cells
    • Sohn J.H., Han K.L., Lee S.H., and Hwang J.K. Protective effects of panduratin A against oxidative damage of tertbutylhydroperoxide in human HepG2 cells. Biol. Pharm. Bull. 28 (2005) 1083-1086
    • (2005) Biol. Pharm. Bull. , vol.28 , pp. 1083-1086
    • Sohn, J.H.1    Han, K.L.2    Lee, S.H.3    Hwang, J.K.4
  • 32
    • 0020067317 scopus 로고
    • Patulin, a further clastogenic mycotoxin, is negative in the SCE assay in Chinese hamster V79-E cells in vitro
    • Thust R., Kneist S., and Mendel J. Patulin, a further clastogenic mycotoxin, is negative in the SCE assay in Chinese hamster V79-E cells in vitro. Mutat. Res. 103 (1982) 91-97
    • (1982) Mutat. Res. , vol.103 , pp. 91-97
    • Thust, R.1    Kneist, S.2    Mendel, J.3
  • 35
    • 72749100505 scopus 로고    scopus 로고
    • van Egmond, H.P., 1987. Current limits and regulations on mycotoxins. In: MYC 87/9.2, joint FAO/WHO/UNEP Second International Conference on mycotoxins, Bangkok, Thailand, September 28-October 3. Food and Agricultural Organization of the United Nations, Rome, Italy.
    • van Egmond, H.P., 1987. Current limits and regulations on mycotoxins. In: MYC 87/9.2, joint FAO/WHO/UNEP Second International Conference on mycotoxins, Bangkok, Thailand, September 28-October 3. Food and Agricultural Organization of the United Nations, Rome, Italy.
  • 37
    • 2542434173 scopus 로고    scopus 로고
    • The role of reactive oxygen species in microcytin-LR-induced DNA damage
    • Žegura B., Lah T.T., and Filipic M. The role of reactive oxygen species in microcytin-LR-induced DNA damage. Toxicology 200 (2004) 59-68
    • (2004) Toxicology , vol.200 , pp. 59-68
    • Žegura, B.1    Lah, T.T.2    Filipic, M.3
  • 38
    • 61449262757 scopus 로고    scopus 로고
    • Patulin-induced genotoxicity and modulation of glutathione in HepG2 cells
    • Zhou S.M., Jiang L.P., Geng Ch.Y., Cao J., and Zhong L.F. Patulin-induced genotoxicity and modulation of glutathione in HepG2 cells. Toxicon 53 (2009) 584-586
    • (2009) Toxicon , vol.53 , pp. 584-586
    • Zhou, S.M.1    Jiang, L.P.2    Geng, Ch.Y.3    Cao, J.4    Zhong, L.F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.