메뉴 건너뛰기




Volumn 22, Issue 2, 2015, Pages 158-166

Tetrameric Ctp1 coordinates DNA binding and DNA bridging in DNA double-strand-break repair

Author keywords

[No Author keywords available]

Indexed keywords

CTP1 PROTEIN; DOUBLE STRANDED DNA; INTRINSICALLY DISORDERED PROTEIN; TETRAMER; UNCLASSIFIED DRUG; CTP1 PROTEIN, S POMBE; DNA BINDING PROTEIN; PROTEIN BINDING; SCHIZOSACCHAROMYCES POMBE PROTEIN;

EID: 84926419222     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.2945     Document Type: Article
Times cited : (51)

References (60)
  • 1
    • 34948899943 scopus 로고    scopus 로고
    • Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template
    • Williams, R.S., Williams, J.S. & Tainer, J.A. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template. Biochem. Cell Biol. 85, 509-520 (2007).
    • (2007) Biochem. Cell Biol. , vol.85 , pp. 509-520
    • Williams, R.S.1    Williams, J.S.2    Tainer, J.A.3
  • 2
    • 84872547120 scopus 로고    scopus 로고
    • Drugging topoisomerases: Lessons and challenges
    • Pommier, Y. Drugging topoisomerases: lessons and challenges. ACS Chem. Biol. 8, 82-95 (2013).
    • (2013) ACS Chem. Biol. , vol.8 , pp. 82-95
    • Pommier, Y.1
  • 3
    • 72149103012 scopus 로고    scopus 로고
    • CtIP links DNA double-strand break sensing to resection
    • You, Z. et al. CtIP links DNA double-strand break sensing to resection. Mol. Cell 36, 954-969 (2009).
    • (2009) Mol. Cell , vol.36 , pp. 954-969
    • You, Z.1
  • 4
    • 70349472553 scopus 로고    scopus 로고
    • Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair
    • Williams, R.S. et al. Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair. Cell 139, 87-99 (2009).
    • (2009) Cell , vol.139 , pp. 87-99
    • Williams, R.S.1
  • 5
    • 34948872046 scopus 로고    scopus 로고
    • Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination
    • Limbo, O. et al. Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination. Mol. Cell 28, 134-146 (2007).
    • (2007) Mol. Cell , vol.28 , pp. 134-146
    • Limbo, O.1
  • 6
    • 53349162987 scopus 로고    scopus 로고
    • CDK targets Sae2 to control DNA-end resection and homologous recombination
    • Huertas, P., Cortes-Ledesma, F., Sartori, A.A., Aguilera, A. & Jackson, S.P. CDK targets Sae2 to control DNA-end resection and homologous recombination. Nature 455, 689-692 (2008).
    • (2008) Nature , vol.455 , pp. 689-692
    • Huertas, P.1    Cortes-Ledesma, F.2    Sartori, A.A.3    Aguilera, A.4    Jackson, S.P.5
  • 7
    • 36549060102 scopus 로고    scopus 로고
    • Human CtIP promotes DNA end resection
    • Sartori, A.A. et al. Human CtIP promotes DNA end resection. Nature 450, 509-514 (2007).
    • (2007) Nature , vol.450 , pp. 509-514
    • Sartori, A.A.1
  • 8
    • 66149114020 scopus 로고    scopus 로고
    • Human CtIP mediates cell cycle control of DNA end resection and double strand break repair
    • Huertas, P. & Jackson, S.P. Human CtIP mediates cell cycle control of DNA end resection and double strand break repair. J. Biol. Chem. 284, 9558-9565 (2009).
    • (2009) J. Biol. Chem. , vol.284 , pp. 9558-9565
    • Huertas, P.1    Jackson, S.P.2
  • 10
    • 17644375501 scopus 로고    scopus 로고
    • Inactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiency
    • Chen, P.L. et al. Inactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiency. Mol. Cell. Biol. 25, 3535-3542 (2005).
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 3535-3542
    • Chen, P.L.1
  • 11
    • 80055077904 scopus 로고    scopus 로고
    • CtIP mutations cause Seckel and Jawad syndromes
    • Qvist, P. et al. CtIP mutations cause Seckel and Jawad syndromes. PLoS Genet. 7, e1002310 (2011).
    • (2011) PLoS Genet. , vol.7 , pp. e1002310
    • Qvist, P.1
  • 12
    • 84896703742 scopus 로고    scopus 로고
    • Quantitation of DNA double-strand break resection intermediates in human cells
    • Zhou, Y., Caron, P., Legube, G. & Paull, T.T. Quantitation of DNA double-strand break resection intermediates in human cells. Nucleic Acids Res. 42, e19 (2014).
    • (2014) Nucleic Acids Res. , vol.42 , pp. e19
    • Zhou, Y.1    Caron, P.2    Legube, G.3    Paull, T.T.4
  • 13
    • 84875974739 scopus 로고    scopus 로고
    • Coincident resection at both ends of random, gamma-induced double-strand breaks requires MRX (MRN), Sae2 (Ctp1), and Mre11-nuclease
    • Westmoreland, J.W. & Resnick, M.A. Coincident resection at both ends of random, gamma-induced double-strand breaks requires MRX (MRN), Sae2 (Ctp1), and Mre11-nuclease. PLoS Genet. 9, e1003420 (2013).
    • (2013) PLoS Genet. , vol.9 , pp. e1003420
    • Westmoreland, J.W.1    Resnick, M.A.2
  • 14
    • 80053447704 scopus 로고    scopus 로고
    • Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks
    • Langerak, P., Mejia-Ramirez, E., Limbo, O. & Russell, P. Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks. PLoS Genet. 7, e1002271 (2011).
    • (2011) PLoS Genet. , vol.7 , pp. e1002271
    • Langerak, P.1    Mejia-Ramirez, E.2    Limbo, O.3    Russell, P.4
  • 15
    • 53649104599 scopus 로고    scopus 로고
    • Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
    • Mimitou, E.P. & Symington, L.S. Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing. Nature 455, 770-774 (2008).
    • (2008) Nature , vol.455 , pp. 770-774
    • Mimitou, E.P.1    Symington, L.S.2
  • 16
    • 23944459784 scopus 로고    scopus 로고
    • Endonucleolytic processing of covalent protein-linked DNA double-strand breaks
    • Neale, M.J., Pan, J. & Keeney, S. Endonucleolytic processing of covalent protein-linked DNA double-strand breaks. Nature 436, 1053-1057 (2005).
    • (2005) Nature , vol.436 , pp. 1053-1057
    • Neale, M.J.1    Pan, J.2    Keeney, S.3
  • 17
    • 67249153681 scopus 로고    scopus 로고
    • Ctp1 and Exonuclease 1, alternative nucleases regulated by the MRN complex, are required for efficient meiotic recombination
    • Farah, J.A., Cromie, G.A. & Smith, G.R. Ctp1 and Exonuclease 1, alternative nucleases regulated by the MRN complex, are required for efficient meiotic recombination. Proc. Natl. Acad. Sci. USA 106, 9356-9361 (2009).
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 9356-9361
    • Farah, J.A.1    Cromie, G.A.2    Smith, G.R.3
  • 18
    • 58149289464 scopus 로고    scopus 로고
    • Distinct requirements for the Rad32(Mre11) nuclease and Ctp1(CtIP) in the removal of covalently bound topoisomerase I and II from DNA
    • Hartsuiker, E., Neale, M.J. & Carr, A.M. Distinct requirements for the Rad32(Mre11) nuclease and Ctp1(CtIP) in the removal of covalently bound topoisomerase I and II from DNA. Mol. Cell 33, 117-123 (2009).
    • (2009) Mol. Cell , vol.33 , pp. 117-123
    • Hartsuiker, E.1    Neale, M.J.2    Carr, A.M.3
  • 19
    • 36248942617 scopus 로고    scopus 로고
    • Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex
    • Lengsfeld, B.M., Rattray, A.J., Bhaskara, V., Ghirlando, R. & Paull, T.T. Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex. Mol. Cell 28, 638-651 (2007).
    • (2007) Mol. Cell , vol.28 , pp. 638-651
    • Lengsfeld, B.M.1    Rattray, A.J.2    Bhaskara, V.3    Ghirlando, R.4    Paull, T.T.5
  • 20
    • 0037169325 scopus 로고    scopus 로고
    • The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements
    • Lobachev, K.S., Gordenin, D.A. & Resnick, M.A. The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements. Cell 108, 183-193 (2002).
    • (2002) Cell , vol.108 , pp. 183-193
    • Lobachev, K.S.1    Gordenin, D.A.2    Resnick, M.A.3
  • 21
    • 70349470626 scopus 로고    scopus 로고
    • A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage
    • Lloyd, J. et al. A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage. Cell 139, 100-111 (2009).
    • (2009) Cell , vol.139 , pp. 100-111
    • Lloyd, J.1
  • 22
    • 3042593642 scopus 로고    scopus 로고
    • Dimerization of CtIP, a BRCA1- and CtBP-interacting protein, is mediated by an N-terminal coiled-coil motif
    • Dubin, M.J. et al. Dimerization of CtIP, a BRCA1- and CtBP-interacting protein, is mediated by an N-terminal coiled-coil motif. J. Biol. Chem. 279, 26932-26938 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 26932-26938
    • Dubin, M.J.1
  • 23
    • 24044538903 scopus 로고    scopus 로고
    • IUPred: Web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content
    • Dosztányi, Z., Csizmok, V., Tompa, P. & Simon, I. IUPred: web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content. Bioinformatics 21, 3433-3434 (2005).
    • (2005) Bioinformatics , vol.21 , pp. 3433-3434
    • Dosztányi, Z.1    Csizmok, V.2    Tompa, P.3    Simon, I.4
  • 24
    • 84876524220 scopus 로고    scopus 로고
    • D2P2: Database of disordered protein predictions
    • Oates, M.E. et al. D2P2: database of disordered protein predictions. Nucleic Acids Res. 41, D508-D516 (2013).
    • (2013) Nucleic Acids Res. , vol.41 , pp. D508-D516
    • Oates, M.E.1
  • 25
    • 84866463338 scopus 로고    scopus 로고
    • Structural biology: Versatility from protein disorder
    • Babu, M.M., Kriwacki, R.W. & Pappu, R.V. Structural biology: versatility from protein disorder. Science 337, 1460-1461 (2012).
    • (2012) Science , vol.337 , pp. 1460-1461
    • Babu, M.M.1    Kriwacki, R.W.2    Pappu, R.V.3
  • 26
    • 0036803243 scopus 로고    scopus 로고
    • Intrinsically unstructured proteins
    • Tompa, P. Intrinsically unstructured proteins. Trends Biochem. Sci. 27, 527-533 (2002).
    • (2002) Trends Biochem. Sci. , vol.27 , pp. 527-533
    • Tompa, P.1
  • 27
    • 84863726680 scopus 로고    scopus 로고
    • Structure of Mre11-Nbs1 complex yields insights into ataxia- telangiectasia-like disease mutations and DNA damage signaling
    • Schiller, C.B. et al. Structure of Mre11-Nbs1 complex yields insights into ataxia- telangiectasia-like disease mutations and DNA damage signaling. Nat. Struct. Mol. Biol. 19, 693-700 (2012).
    • (2012) Nat. Struct. Mol. Biol. , vol.19 , pp. 693-700
    • Schiller, C.B.1
  • 28
    • 20744436198 scopus 로고    scopus 로고
    • ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1
    • You, Z., Chahwan, C., Bailis, J., Hunter, T. & Russell, P. ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1. Mol. Cell. Biol. 25, 5363-5379 (2005).
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 5363-5379
    • You, Z.1    Chahwan, C.2    Bailis, J.3    Hunter, T.4    Russell, P.5
  • 29
    • 44349086462 scopus 로고    scopus 로고
    • + gene in DNA double-strand break repair in association with the Mre11-Rad50-Nbs1 complex
    • + gene in DNA double-strand break repair in association with the Mre11-Rad50-Nbs1 complex. Mol. Cell. Biol. 28, 3639-3651 (2008).
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 3639-3651
    • Akamatsu, Y.1
  • 30
    • 52949149420 scopus 로고    scopus 로고
    • Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair
    • Williams, R.S. et al. Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair. Cell 135, 97-109 (2008).
    • (2008) Cell , vol.135 , pp. 97-109
    • Williams, R.S.1
  • 31
    • 0036682314 scopus 로고    scopus 로고
    • The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair
    • Hopfner, K.P. et al. The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair. Nature 418, 562-566 (2002).
    • (2002) Nature , vol.418 , pp. 562-566
    • Hopfner, K.P.1
  • 32
    • 84896125249 scopus 로고    scopus 로고
    • ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling
    • Deshpande, R.A. et al. ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling. EMBO J. 33, 482-500 (2014).
    • (2014) EMBO J. , vol.33 , pp. 482-500
    • Deshpande, R.A.1
  • 33
    • 84857820399 scopus 로고    scopus 로고
    • A human XRCC4-XLF complex bridges DNA
    • Andres, S.N. et al. A human XRCC4-XLF complex bridges DNA. Nucleic Acids Res. 40, 1868-1878 (2012).
    • (2012) Nucleic Acids Res. , vol.40 , pp. 1868-1878
    • Andres, S.N.1
  • 34
    • 0024420685 scopus 로고
    • Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin
    • Hsiang, Y.H., Lihou, M.G. & Liu, L.F. Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin. Cancer Res. 49, 5077-5082 (1989).
    • (1989) Cancer Res. , vol.49 , pp. 5077-5082
    • Hsiang, Y.H.1    Lihou, M.G.2    Liu, L.F.3
  • 35
    • 14644420930 scopus 로고    scopus 로고
    • Interfacial inhibition of macromolecular interactions: Nature's paradigm for drug discovery
    • Pommier, Y. & Cherfils, J. Interfacial inhibition of macromolecular interactions: nature's paradigm for drug discovery. Trends Pharmacol. Sci. 26, 138-145 (2005).
    • (2005) Trends Pharmacol. Sci. , vol.26 , pp. 138-145
    • Pommier, Y.1    Cherfils, J.2
  • 36
    • 84877824758 scopus 로고    scopus 로고
    • Processing of damaged DNA ends for double-strand break repair in mammalian cells
    • Povirk, L.F. Processing of damaged DNA ends for double-strand break repair in mammalian cells. ISRN Mol. Biol. 2012, 345805 (2012).
    • (2012) ISRN Mol. Biol. , vol.2012 , pp. 345805
    • Povirk, L.F.1
  • 37
    • 40849094757 scopus 로고    scopus 로고
    • Functional interactions between Sae2 and the Mre11 complex
    • Kim, H.S. et al. Functional interactions between Sae2 and the Mre11 complex. Genetics 178, 711-723 (2008).
    • (2008) Genetics , vol.178 , pp. 711-723
    • Kim, H.S.1
  • 38
    • 84862282124 scopus 로고    scopus 로고
    • CtIP protein dimerization is critical for its recruitment to chromosomal DNA double-stranded breaks
    • Wang, H. et al. CtIP protein dimerization is critical for its recruitment to chromosomal DNA double-stranded breaks. J. Biol. Chem. 287, 21471-21480 (2012).
    • (2012) J. Biol. Chem. , vol.287 , pp. 21471-21480
    • Wang, H.1
  • 39
    • 84908045717 scopus 로고    scopus 로고
    • Sae2 promotes dsDNA endonuclease activity within Mre11- Rad50-Xrs2 to resect DNA breaks
    • Cannavo, E. & Cejka, P. Sae2 promotes dsDNA endonuclease activity within Mre11- Rad50-Xrs2 to resect DNA breaks. Nature 514, 122-125 (2014).
    • (2014) Nature , vol.514 , pp. 122-125
    • Cannavo, E.1    Cejka, P.2
  • 40
    • 78649460650 scopus 로고    scopus 로고
    • DNA end resection by CtIP and exonuclease 1 prevents genomic instability
    • Eid, W. et al. DNA end resection by CtIP and exonuclease 1 prevents genomic instability. EMBO Rep. 11, 962-968 (2010).
    • (2010) EMBO Rep. , vol.11 , pp. 962-968
    • Eid, W.1
  • 41
    • 78650995499 scopus 로고    scopus 로고
    • An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway
    • Zhang, Y. & Jasin, M. An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway. Nat. Struct. Mol. Biol. 18, 80-84 (2011).
    • (2011) Nat. Struct. Mol. Biol. , vol.18 , pp. 80-84
    • Zhang, Y.1    Jasin, M.2
  • 42
    • 24944540931 scopus 로고    scopus 로고
    • Mesoscale conformational changes in the DNA-repair complex Rad50/Mre11/Nbs1 upon binding DNA
    • Moreno-Herrero, F. et al. Mesoscale conformational changes in the DNA-repair complex Rad50/Mre11/Nbs1 upon binding DNA. Nature 437, 440-443 (2005).
    • (2005) Nature , vol.437 , pp. 440-443
    • Moreno-Herrero, F.1
  • 43
    • 10344240414 scopus 로고    scopus 로고
    • Chromosome fragmentation after induction of a double-strand break is an active process prevented by the RMX repair complex
    • Lobachev, K., Vitriol, E., Stemple, J., Resnick, M.A. & Bloom, K. Chromosome fragmentation after induction of a double-strand break is an active process prevented by the RMX repair complex. Curr. Biol. 14, 2107-2112 (2004).
    • (2004) Curr. Biol. , vol.14 , pp. 2107-2112
    • Lobachev, K.1    Vitriol, E.2    Stemple, J.3    Resnick, M.A.4    Bloom, K.5
  • 44
    • 0035930342 scopus 로고    scopus 로고
    • Promotion of Dnl4- catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes
    • Chen, L., Trujillo, K., Ramos, W., Sung, P. & Tomkinson, A.E. Promotion of Dnl4- catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes. Mol. Cell 8, 1105-1115 (2001).
    • (2001) Mol. Cell , vol.8 , pp. 1105-1115
    • Chen, L.1    Trujillo, K.2    Ramos, W.3    Sung, P.4    Tomkinson, A.E.5
  • 45
    • 0036926615 scopus 로고    scopus 로고
    • A new vector for high-throughput, ligation-independent cloning encoding a tobacco etch virus protease cleavage site
    • Stols, L. et al. A new vector for high-throughput, ligation-independent cloning encoding a tobacco etch virus protease cleavage site. Protein Expr. Purif. 25, 8-15 (2002).
    • (2002) Protein Expr. Purif. , vol.25 , pp. 8-15
    • Stols, L.1
  • 46
    • 0027447099 scopus 로고
    • A self-consistent method for the analysis of protein secondary structure from circular dichroism
    • Sreerama, N. & Woody, R.W. A self-consistent method for the analysis of protein secondary structure from circular dichroism. Anal. Biochem. 209, 32-44 (1993).
    • (1993) Anal. Biochem. , vol.209 , pp. 32-44
    • Sreerama, N.1    Woody, R.W.2
  • 47
    • 0033042935 scopus 로고    scopus 로고
    • Estimation of the number of alpha-helical and beta-strand segments in proteins using circular dichroism spectroscopy
    • Sreerama, N., Venyaminov, S.Y. & Woody, R.W. Estimation of the number of alpha-helical and beta-strand segments in proteins using circular dichroism spectroscopy. Protein Sci. 8, 370-380 (1999).
    • (1999) Protein Sci. , vol.8 , pp. 370-380
    • Sreerama, N.1    Venyaminov, S.Y.2    Woody, R.W.3
  • 48
    • 3242877618 scopus 로고    scopus 로고
    • DICHROWEB, an online server for protein secondary structure analyses from circular dichroism spectroscopic data
    • Whitmore, L. & Wallace, B.A. DICHROWEB, an online server for protein secondary structure analyses from circular dichroism spectroscopic data. Nucleic Acids Res. 32, W668-W673 (2004).
    • (2004) Nucleic Acids Res. , vol.32 , pp. W668-W673
    • Whitmore, L.1    Wallace, B.A.2
  • 49
    • 0031059866 scopus 로고    scopus 로고
    • Processing of X-ray diffraction data collected in oscillation mode
    • Otwinowski, Z. & Minor, W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276, 307-326 (1997).
    • (1997) Methods Enzymol. , vol.276 , pp. 307-326
    • Otwinowski, Z.1    Minor, W.2
  • 50
    • 34447508216 scopus 로고    scopus 로고
    • Phaser crystallographic software
    • McCoy, A.J. et al. Phaser crystallographic software. J. Appl. Crystallogr. 40, 658-674 (2007).
    • (2007) J. Appl. Crystallogr. , vol.40 , pp. 658-674
    • McCoy, A.J.1
  • 51
    • 4143118964 scopus 로고    scopus 로고
    • Crystal structure of the coiled-coil dimerization motif of geminin: Structural and functional insights on DNA replication regulation
    • Thépaut, M. et al. Crystal structure of the coiled-coil dimerization motif of geminin: structural and functional insights on DNA replication regulation. J. Mol. Biol. 342, 275-287 (2004).
    • (2004) J. Mol. Biol. , vol.342 , pp. 275-287
    • Thépaut, M.1
  • 52
    • 79953737180 scopus 로고    scopus 로고
    • Overview of the CCP4 suite and current developments
    • Winn, M.D. et al. Overview of the CCP4 suite and current developments. Acta Crystallogr. D Biol. Crystallogr. 67, 235-242 (2011).
    • (2011) Acta Crystallogr. D Biol. Crystallogr. , vol.67 , pp. 235-242
    • Winn, M.D.1
  • 55
    • 76449098262 scopus 로고    scopus 로고
    • PHENIX: A comprehensive Python-based system for macromolecular structure solution
    • Adams, P.D. et al. PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta Crystallogr. D Biol. Crystallogr. 66, 213-221 (2010).
    • (2010) Acta Crystallogr. D Biol. Crystallogr. , vol.66 , pp. 213-221
    • Adams, P.D.1
  • 57
    • 0026025891 scopus 로고
    • Molecular genetic analysis of fission yeast Schizosaccharomyces pombe
    • Moreno, S., Klar, A. & Nurse, P. Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol. 194, 795-823 (1991).
    • (1991) Methods Enzymol. , vol.194 , pp. 795-823
    • Moreno, S.1    Klar, A.2    Nurse, P.3
  • 58
    • 0030811046 scopus 로고    scopus 로고
    • Identification and preliminary characterization of p31, a new PSTAIRE-related protein in fission yeast
    • Tournier, S., Gachet, Y. & Hyams, J.S. Identification and preliminary characterization of p31, a new PSTAIRE-related protein in fission yeast. Yeast 13, 727-734 (1997).
    • (1997) Yeast , vol.13 , pp. 727-734
    • Tournier, S.1    Gachet, Y.2    Hyams, J.S.3
  • 59
    • 77949550655 scopus 로고    scopus 로고
    • γH2A binds Brc1 to maintain genome integrity during S-phase
    • Williams, J.S. et al. γH2A binds Brc1 to maintain genome integrity during S-phase. EMBO J. 29, 1136-1148 (2010).
    • (2010) EMBO J. , vol.29 , pp. 1136-1148
    • Williams, J.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.