In vivo mechanical loading rapidly activates β-catenin signaling in osteocytes through a prostaglandin mediated mechanism

Bone

Volumn 76, Issue , 2015, Pages 58-66

  Lara Castillo, N ^a   Kim Weroha, N A ^a   Kamel, M A ^a   Javaheri, B ^b   Ellies, D L ^c   Krumlauf, R E ^a,d   Thiagarajan, G ^e   Johnson, M L ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY SCHOOL OF DENTISTRY   (United States)

^b ROYAL VETERINARY COLLEGE   (United Kingdom)

^c OsteoGeneX Inc   (United States)

^d STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

^e UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

Mechanical loading; Osteocyte; Prostaglandin; Wnt catenin signaling

Indexed keywords

BETA CATENIN; CARPROFEN; DICKKOPF 1 PROTEIN; PROSTAGLANDIN; PROSTAGLANDIN E RECEPTOR 2; SCLEROSTIN; DKK1 PROTEIN, MOUSE; GLYCOPROTEIN; SIGNAL PEPTIDE; SOST PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CELL COUNT; CELLULAR DISTRIBUTION; CORTICAL BONE; DKK1 GENE; FEMALE; FOREARM; GENE; GENE EXPRESSION; HOMEOSTASIS; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; OSTEOCYTE; PROSTAGLANDIN RELEASE; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SHEAR STRESS; ULNA; ANIMAL; CELL LINE; FINITE ELEMENT ANALYSIS; GENETICS; KINETICS; MECHANICAL STRESS; METABOLISM; SIGNAL TRANSDUCTION;

ANIMALS; BETA CATENIN; CELL LINE; FEMALE; FINITE ELEMENT ANALYSIS; GLYCOPROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KINETICS; MICE; OSTEOCYTES; PROSTAGLANDINS; SIGNAL TRANSDUCTION; STRESS, MECHANICAL;

EID: 84926393989     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2015.03.019     Document Type: Article

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