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Volumn 28, Issue 4, 2014, Pages 1582-1592

In situ intracellular calcium oscillations in osteocytes in intact mouse long bones under dynamic mechanical loading

Author keywords

Acunocanalicular system; Endoplasmic reticulum; Fluorescence recovery after photobleaching; Mechanotransduction; Purinergic receptor; Shear stress

Indexed keywords

CALCIUM; PHOSPHOLIPASE C; PURINERGIC P2 RECEPTOR;

EID: 84901037100     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.13-237578     Document Type: Article
Times cited : (91)

References (60)
  • 1
    • 79251493453 scopus 로고    scopus 로고
    • The amazing osteocyte
    • Bonewald, L. F. (2011) The amazing osteocyte. J. Bone Miner. Res. 26, 229-238
    • (2011) J. Bone Miner. Res. , vol.26 , pp. 229-238
    • Bonewald, L.F.1
  • 3
    • 84863111789 scopus 로고    scopus 로고
    • Osteocyte network; a negative regulatory system for bone mass augmented by the induction of rankl in osteoblasts and sost in osteocytes at unloading
    • Moriishi, T., Fukuyama, R., Ito, M., Miyazaki, T., Maeno, T., Kawai, Y., Komori, H., and Komori, T. (2012) Osteocyte network; a negative regulatory system for bone mass augmented by the induction of Rankl in osteoblasts and Sost in osteocytes at unloading. PLoS One 7, e40143
    • (2012) PLoS One , vol.7
    • Moriishi, T.1    Fukuyama, R.2    Ito, M.3    Miyazaki, T.4    Maeno, T.5    Kawai, Y.6    Komori, H.7    Komori, T.8
  • 5
    • 67651027592 scopus 로고    scopus 로고
    • Fluid and solute transport in bone: Flow-induced mechanotransduction
    • Fritton, S. P., and Weinbaum, S. (2009) Fluid and solute transport in bone: flow-induced mechanotransduction. Annu. Rev. Fluid Mech. 41, 347-374
    • (2009) Annu. Rev. Fluid Mech. , vol.41 , pp. 347-374
    • Fritton, S.P.1    Weinbaum, S.2
  • 9
    • 77957755212 scopus 로고    scopus 로고
    • Activation of -catenin signaling in mlo-y4 osteocytic cells versus 2t3 osteoblastic cells by fluid flow shear stress and pge2 implications for the study of mechanosensation in bone
    • Kamel, M. A., Picconi, J. L., Lara-Castillo, N., and Johnson, M. L. (2010) Activation of -catenin signaling in MLO-Y4 osteocytic cells versus 2T3 osteoblastic cells by fluid flow shear stress and PGE2: implications for the study of mechanosensation in bone. Bone 47, 872-881
    • (2010) Bone , vol.47 , pp. 872-881
    • Kamel, M.A.1    Picconi, J.L.2    Lara-Castillo, N.3    Johnson, M.L.4
  • 10
    • 0029617377 scopus 로고
    • Pulsating fluid flow increases nitric oxide (no) synthesis by osteocytes but not periosteal fibroblasts-correlation with prostaglandin upregulation
    • Klein-Nulend, J., Semeins, C. M., Ajubi, N. E., Nijweide, P. J., and Burger, E. H. (1995) Pulsating fluid flow increases nitric oxide (NO) synthesis by osteocytes but not periosteal fibroblasts-correlation with prostaglandin upregulation. Biochem. Biophys. Res. Commun. 217, 640-648
    • (1995) Biochem. Biophys. Res. Commun. , vol.217 , pp. 640-648
    • Klein-Nulend, J.1    Semeins, C.M.2    Ajubi, N.E.3    Nijweide, P.J.4    Burger, E.H.5
  • 11
    • 84865129170 scopus 로고    scopus 로고
    • Fluid flow-induced calcium response in early or late differentiated osteoclasts
    • Li, P., Hu, M., Sun, S., Zhang, Y., Gao, Y., Long, M., Huo, B., and Zhang, D. (2012) Fluid flow-induced calcium response in early or late differentiated osteoclasts. Ann. Biomed. Eng. 40, 1874-1883
    • (2012) Ann. Biomed. Eng. , vol.40 , pp. 1874-1883
    • Li, P.1    Hu, M.2    Sun, S.3    Zhang, Y.4    Gao, Y.5    Long, M.6    Huo, B.7    Zhang, D.8
  • 14
    • 0036510537 scopus 로고    scopus 로고
    • Intercellular calcium signaling occurs between human osteoblasts and osteoclasts and requires activation of osteoclast p2x7 receptors
    • Jorgensen, N. R., Henriksen, Z., Sorensen, O. H., Eriksen, E. F., Civitelli, R., and Steinberg, T. H. (2002) Intercellular calcium signaling occurs between human osteoblasts and osteoclasts and requires activation of osteoclast P2X7 receptors. J. Biol. Chem. 277, 7574-7580
    • (2002) J. Biol. Chem. , vol.277 , pp. 7574-7580
    • Jorgensen, N.R.1    Henriksen, Z.2    Sorensen, O.H.3    Eriksen, E.F.4    Civitelli, R.5    Steinberg, T.H.6
  • 15
    • 33645221301 scopus 로고    scopus 로고
    • The predominant mechanism of intercellular calcium wave propagation changes during long-term culture of human osteoblast-like cells
    • Henriksen, Z., Hiken, J. F., Steinberg, T. H., and Jorgensen, N. R. (2006) The predominant mechanism of intercellular calcium wave propagation changes during long-term culture of human osteoblast-like cells. Cell Calcium 39, 435-444
    • (2006) Cell Calcium , vol.39 , pp. 435-444
    • Henriksen, Z.1    Hiken, J.F.2    Steinberg, T.H.3    Jorgensen, N.R.4
  • 17
    • 0035918140 scopus 로고    scopus 로고
    • Osteopontin gene regulation by oscillatory fluid flow via intracellular calcium mobilization and activation of mitogen-activated protein kinase in mc3t3-e1 osteoblasts
    • You, J., Reilly, G. C., Zhen, X., Yellowley, C. E., Chen, Q., Donahue, H. J., and Jacobs, C. R. (2001) Osteopontin gene regulation by oscillatory fluid flow via intracellular calcium mobilization and activation of mitogen-activated protein kinase in MC3T3-E1 osteoblasts. J. Biol. Chem. 276, 13365-13371
    • (2001) J. Biol. Chem. , vol.276 , pp. 13365-13371
    • You, J.1    Reilly, G.C.2    Zhen, X.3    Yellowley, C.E.4    Chen, Q.5    Donahue, H.J.6    Jacobs, C.R.7
  • 18
    • 84857243185 scopus 로고    scopus 로고
    • Osteocytic network is more responsive in calcium signaling than osteoblastic network under fluid flow
    • Lu, X. L., Huo, B., Chiang, V., and Guo, X. E. (2012) Osteocytic network is more responsive in calcium signaling than osteoblastic network under fluid flow. J. Bone Miner. Res. 27, 563-574
    • (2012) J. Bone Miner. Res. , vol.27 , pp. 563-574
    • Lu, X.L.1    Huo, B.2    Chiang, V.3    Guo, X.E.4
  • 19
    • 84873498185 scopus 로고    scopus 로고
    • Spatiotemporal properties of intracellular calcium signaling in osteocytic and osteoblastic cell networks under fluid flow
    • Jing, D., Lu, X. L., Luo, E., Sajda, P., Leong, P. L., and Guo, X. E. (2013) Spatiotemporal properties of intracellular calcium signaling in osteocytic and osteoblastic cell networks under fluid flow. Bone 53, 531-540
    • (2013) Bone , vol.53 , pp. 531-540
    • Jing, D.1    Lu, X.L.2    Luo, E.3    Sajda, P.4    Leong, P.L.5    Guo, X.E.6
  • 20
    • 77649273816 scopus 로고    scopus 로고
    • An atp-dependent mechanism mediates intercellular calcium signaling in bone cell network under single cell nanoindentation
    • Huo, B., Lu, X. L., Costa, K. D., Xu, Q., and Guo, X. E. (2010) An ATP-dependent mechanism mediates intercellular calcium signaling in bone cell network under single cell nanoindentation. Cell Calcium 47, 234-241
    • (2010) Cell Calcium , vol.47 , pp. 234-241
    • Huo, B.1    Lu, X.L.2    Costa, K.D.3    Xu, Q.4    Guo, X.E.5
  • 22
    • 84872179683 scopus 로고    scopus 로고
    • Ex vivo real-time observation of ca2-signaling in living bone in response to shear stress applied on the bone surface
    • Ishihara, Y., Sugawara, Y., Kamioka, H., Kawanabe, N., Hayano, S., Balam, T. A., Naruse, K., and Yamashiro, T. (2013) Ex vivo real-time observation of Ca2-signaling in living bone in response to shear stress applied on the bone surface. Bone 53, 204-215
    • (2013) Bone , vol.53 , pp. 204-215
    • Ishihara, Y.1    Sugawara, Y.2    Kamioka, H.3    Kawanabe, N.4    Hayano, S.5    Balam, T.A.6    Naruse, K.7    Yamashiro, T.8
  • 23
    • 84857229741 scopus 로고    scopus 로고
    • In situ imaging of the autonomous intracellular Ca2-oscillations of osteoblasts and osteocytes in bone
    • Ishihara, Y., Sugawara, Y., Kamioka, H., Kawanabe, N., Kurosaka, H., Naruse, K., and Yamashiro, T. (2012) In situ imaging of the autonomous intracellular Ca2-oscillations of osteoblasts and osteocytes in bone. Bone 50, 842-852
    • (2012) Bone , vol.50 , pp. 842-852
    • Ishihara, Y.1    Sugawara, Y.2    Kamioka, H.3    Kawanabe, N.4    Kurosaka, H.5    Naruse, K.6    Yamashiro, T.7
  • 24
    • 28844442933 scopus 로고    scopus 로고
    • Non-invasive axial loading of mouse tibiae increases cortical bone formation and modifies trabecular organization: A new model to study cortical and cancellous compartments in a single loaded element
    • De Souza, R. L., Matsuura, M., Eckstein, F., Rawlinson, S. C., Lanyon, L. E., and Pitsillides, A. A. (2005) Non-invasive axial loading of mouse tibiae increases cortical bone formation and modifies trabecular organization: a new model to study cortical and cancellous compartments in a single loaded element. Bone 37, 810-818
    • (2005) Bone , vol.37 , pp. 810-818
    • De Souza, R.L.1    Matsuura, M.2    Eckstein, F.3    Rawlinson, S.C.4    Lanyon, L.E.5    Pitsillides, A.A.6
  • 25
    • 20444421878 scopus 로고    scopus 로고
    • Loading induces site-specific increases in mineral content assessed by microcomputed tomography of the mouse tibia
    • Fritton, J. C., Myers, E. R., Wright, T. M., and van der Meulen, M. C. (2005) Loading induces site-specific increases in mineral content assessed by microcomputed tomography of the mouse tibia. Bone 36, 1030-1038
    • (2005) Bone , vol.36 , pp. 1030-1038
    • Fritton, J.C.1    Myers, E.R.2    Wright, T.M.3    Van Der Meulen, M.C.4
  • 26
    • 77956807497 scopus 로고    scopus 로고
    • Aged mice have enhanced endocortical response and normal periosteal response compared with young-adult mice following 1 week of axial tibial compression
    • Brodt, M. D., and Silva, M. J. (2010) Aged mice have enhanced endocortical response and normal periosteal response compared with young-adult mice following 1 week of axial tibial compression. J. Bone Miner. Res. 25, 2006-2015
    • (2010) J. Bone Miner. Res. , vol.25 , pp. 2015
    • Brodt, M.D.1    Silva, M.J.2
  • 27
    • 84859709984 scopus 로고    scopus 로고
    • Tibial loading increases osteogenic gene expression and cortical bone volume in mature and middle-aged mice
    • Silva, M. J., Brodt, M. D., Lynch, M. A., Stephens, A. L., Wood, D. J., and Civitelli, R. (2012) Tibial loading increases osteogenic gene expression and cortical bone volume in mature and middle-aged mice. PLoS One 7, e34980
    • (2012) PLoS One , vol.7
    • Silva, M.J.1    Brodt, M.D.2    Lynch, M.A.3    Stephens, A.L.4    Wood, D.J.5    Civitelli, R.6
  • 30
    • 38149111214 scopus 로고    scopus 로고
    • Differential outgrowth of axons and their branches is regulated by localized calcium transients
    • Hutchins, B. I., and Kalil, K. (2008) Differential outgrowth of axons and their branches is regulated by localized calcium transients. J. Neurosci. 28, 143-153
    • (2008) J. Neurosci. , vol.28 , pp. 143-153
    • Hutchins, B.I.1    Kalil, K.2
  • 31
    • 79251485661 scopus 로고    scopus 로고
    • Real-time measurement of solute transport within the lacunar-canalicular system of mechanically loaded bone: Direct evidence for loadinduced fluid flow
    • Price, C., Zhou, X., Li, W., and Wang, L. (2011) Real-time measurement of solute transport within the lacunar-canalicular system of mechanically loaded bone: direct evidence for loadinduced fluid flow. J. Bone Miner. Res. 26, 277-285
    • (2011) J. Bone Miner. Res. , vol.26 , pp. 277-285
    • Price, C.1    Zhou, X.2    Li, W.3    Wang, L.4
  • 32
    • 0031647592 scopus 로고    scopus 로고
    • A pyramid approach to subpixel registration based on intensity
    • Thevenaz, P., Ruttimann, U. E., and Unser, M. (1998) A pyramid approach to subpixel registration based on intensity. IEEE Trans. Image Process. 7, 27-41
    • (1998) IEEE Trans. Image Process. , vol.7 , pp. 27-41
    • Thevenaz, P.1    Ruttimann, U.E.2    Unser, M.3
  • 33
    • 84864779201 scopus 로고    scopus 로고
    • Calcium response in osteocytic networks under steady and oscillatory fluid flow
    • Lu, X. L., Huo, B., Park, M., and Guo, X. E. (2012) Calcium response in osteocytic networks under steady and oscillatory fluid flow. Bone 51, 466-473
    • (2012) Bone , vol.51 , pp. 466-473
    • Lu, X.L.1    Huo, B.2    Park, M.3    Guo, X.E.4
  • 34
    • 0028386524 scopus 로고
    • A model for the excitation of osteocytes by mechanical loading-induced bone fluid shear stresses
    • Weinbaum, S., Cowin, S. C., and Zeng, Y. (1994) A model for the excitation of osteocytes by mechanical loading-induced bone fluid shear stresses. J. Biomech. 27, 339-360
    • (1994) J. Biomech. , vol.27 , pp. 339-360
    • Weinbaum, S.1    Cowin, S.C.2    Zeng, Y.3
  • 35
    • 0029950887 scopus 로고    scopus 로고
    • Neomycin inhibits histamine and thapsigargin mediated ca2-entry in ddt1 mf-2 cells independent of phospholipase c activation
    • Sipma, H., Van der Zee, L., Den Hertog, A., and Nelemans, A. (1996) Neomycin inhibits histamine and thapsigargin mediated Ca2-entry in DDT1 MF-2 cells independent of phospholipase C activation. Eur. J. Pharmacol. 305, 207-212
    • (1996) Eur. J. Pharmacol. , vol.305 , pp. 207-212
    • Sipma, H.1    Van Der Zee, L.2    Den Hertog, A.3    Nelemans, A.4
  • 36
    • 0032875177 scopus 로고    scopus 로고
    • Different receptors mediating the inhibitory action of exogenous atp and endogenously released purines on guineapig intestinal peristalsis
    • Heinemann, A., Shahbazian, A., Bartho, L., and Holzer, P. (1999) Different receptors mediating the inhibitory action of exogenous ATP and endogenously released purines on guineapig intestinal peristalsis. Br. J. Pharmacol. 128, 313-320
    • (1999) Br. J. Pharmacol. , vol.128 , pp. 313-320
    • Heinemann, A.1    Shahbazian, A.2    Bartho, L.3    Holzer, P.4
  • 37
    • 0030927307 scopus 로고    scopus 로고
    • Extracellular atp modulates [ca2-]i in retinoic acidtreated embryonic chondrocytes
    • Hung, C. T., Allen, F. D., Mansfield, K. D., and Shapiro, I. M. (1997) Extracellular ATP modulates [Ca2-]i in retinoic acidtreated embryonic chondrocytes. Am. J. Physiol. 272, C1611-C1617
    • (1997) Am. J. Physiol. , vol.272
    • Hung, C.T.1    Allen, F.D.2    Mansfield, K.D.3    Shapiro, I.M.4
  • 38
    • 0033060335 scopus 로고    scopus 로고
    • Inhibition of gap junction communication in alveolar epithelial cells by 18-glycyrrhetinic acid
    • Guo, Y., Martinez-Williams, C., Gilbert, K. A., and Rannels, D. E. (1999) Inhibition of gap junction communication in alveolar epithelial cells by 18-glycyrrhetinic acid. Am. J. Physiol. 276, L1018-L1026
    • (1999) Am. J. Physiol. , vol.276
    • Guo, Y.1    Martinez-Williams, C.2    Gilbert, K.A.3    Rannels, D.E.4
  • 39
    • 1642397011 scopus 로고    scopus 로고
    • Nnc 55-"0396 [(1s,2s)-2-(2-(n-[(3-benzimidazol-2-yl)propyl]-n- methylamino)ethyl)-6-fluoro-1,2, 3,4-tetrahydro-1-isopropyl-2-naphtyl cyclopropanecarboxylate dihydrochloride]: A new selective inhibitor of t-type calcium channels
    • Huang, L., Keyser, B. M., Tagmose, T. M., Hansen, J. B., Taylor, J. T., Zhuang, H., Zhang, M., Ragsdale, D. S., and Li, M. (2004) NNC 55-0396 [(1S,2S)-2-(2-(N-[(3-benzimidazol-2-yl)propyl]-N-methylamino)ethyl)-6-fluoro-1, 2, 3,4-tetrahydro-1-isopropyl-2-naphtyl cyclopropanecarboxylate dihydrochloride]: a new selective inhibitor of T-type calcium channels. J. Pharmacol. Exp. Ther. 309, 193-199
    • (2004) J. Pharmacol. Exp. Ther. , vol.309 , pp. 193-199
    • Huang, L.1    Keyser, B.M.2    Tagmose, T.M.3    Hansen, J.B.4    Taylor, J.T.5    Zhuang, H.6    Zhang, M.7    Ragsdale, D.S.8    Li, M.9
  • 40
    • 0037967718 scopus 로고    scopus 로고
    • Antiproliferative effect of ca2-channel blockers on human epidermoid carcinoma a431 cells
    • Yoshida, J., Ishibashi, T., and Nishio, M. (2003) Antiproliferative effect of Ca2-channel blockers on human epidermoid carcinoma A431 cells. Eur. J. Pharmacol. 472, 23-31
    • (2003) Eur. J. Pharmacol. , vol.472 , pp. 23-31
    • Yoshida, J.1    Ishibashi, T.2    Nishio, M.3
  • 42
    • 84876735183 scopus 로고    scopus 로고
    • Quantifying load-induced solute transport and solutematrix interactions within the osteocyte lacunar-canalicular system
    • Wang, B., Zhou, X., Price, C., Li, W., Pan, J., and Wang, L. (2013) Quantifying load-induced solute transport and solutematrix interactions within the osteocyte lacunar-canalicular system. J. Bone Miner. Res. 28, 1075-1086
    • (2013) J. Bone Miner. Res. , vol.28 , pp. 1075-1086
    • Wang, B.1    Zhou, X.2    Price, C.3    Li, W.4    Pan, J.5    Wang, L.6
  • 43
    • 40849106249 scopus 로고    scopus 로고
    • Osteocytes, mechanosensing and wnt signaling
    • Bonewald, L. F., and Johnson, M. L. (2008) Osteocytes, mechanosensing and Wnt signaling. Bone 42, 606-615
    • (2008) Bone , vol.42 , pp. 606-615
    • Bonewald, L.F.1    Johnson, M.L.2
  • 44
    • 49149090893 scopus 로고    scopus 로고
    • Osteocyte morphology in fibula and calvaria-is there a role for mechanosensing?
    • Vatsa, A., Breuls, R. G., Semeins, C. M., Salmon, P. L., Smit, T. H., and Klein-Nulend, J. (2008) Osteocyte morphology in fibula and calvaria -is there a role for mechanosensing? Bone 43, 452-458
    • (2008) Bone , vol.43 , pp. 452-458
    • Vatsa, A.1    Breuls, R.G.2    Semeins, C.M.3    Salmon, P.L.4    Smit, T.H.5    Klein-Nulend, J.6
  • 45
    • 84855858086 scopus 로고    scopus 로고
    • Structural differences in the osteocyte network between the calvaria and long bone revealed by three-dimensional fluorescence morphometry, possibly reflecting distinct mechano-adaptations and sensitivities
    • Himeno-Ando, A., Izumi, Y., Yamaguchi, A., and Iimura, T. (2012) Structural differences in the osteocyte network between the calvaria and long bone revealed by three-dimensional fluorescence morphometry, possibly reflecting distinct mechano-adaptations and sensitivities. Biochem. Biophys. Res. Commun. 417, 765-770
    • (2012) Biochem. Biophys. Res. Commun. , vol.417 , pp. 765-770
    • Himeno-Ando, A.1    Izumi, Y.2    Yamaguchi, A.3    Iimura, T.4
  • 46
    • 68049108296 scopus 로고    scopus 로고
    • Regulation of mechanical signals in bone
    • Judex, S., Gupta, S., and Rubin, C. (2009) Regulation of mechanical signals in bone. Orthod. Craniofac. Res. 12, 94-104
    • (2009) Orthod. Craniofac. Res. , vol.12 , pp. 94-104
    • Judex, S.1    Gupta, S.2    Rubin, C.3
  • 47
    • 70349974398 scopus 로고    scopus 로고
    • Mechanical signaling for bone modeling and remodeling
    • Robling, A. G., and Turner, C. H. (2009) Mechanical signaling for bone modeling and remodeling. Crit. Rev. Eukaryot. Gene Expr. 19, 319-338
    • (2009) Crit. Rev. Eukaryot. Gene Expr. , vol.19 , pp. 319-338
    • Robling, A.G.1    Turner, C.H.2
  • 48
    • 23844535859 scopus 로고    scopus 로고
    • Mechanisms by which exercise improves bone strength
    • Turner, C. H., and Robling, A. G. (2005) Mechanisms by which exercise improves bone strength. J. Bone Miner. Metab. 23(Suppl.), 16-22
    • (2005) J. Bone Miner. Metab. , vol.23 , Issue.SUPPL. , pp. 16-22
    • Turner, C.H.1    Robling, A.G.2
  • 49
    • 77956461991 scopus 로고    scopus 로고
    • Osteocyte: The unrecognized side of bone tissue
    • Rochefort, G. Y., Pallu, S., and Benhamou, C. L. (2010) Osteocyte: the unrecognized side of bone tissue. Osteoporos. Int. 21, 1457-1469
    • (2010) Osteoporos. Int. , vol.21 , pp. 1457-1469
    • Rochefort, G.Y.1    Pallu, S.2    Benhamou, C.L.3
  • 53
    • 0034792594 scopus 로고    scopus 로고
    • A model for strain amplification in the actin cytoskeleton of osteocytes due to fluid drag on pericellular matrix
    • You, L., Cowin, S. C., Schaffler, M. B., and Weinbaum, S. (2001) A model for strain amplification in the actin cytoskeleton of osteocytes due to fluid drag on pericellular matrix. J. Biomech. 34, 1375-1386
    • (2001) J. Biomech. , vol.34 , pp. 1375-1386
    • You, L.1    Cowin, S.C.2    Schaffler, M.B.3    Weinbaum, S.4
  • 55
    • 34249871139 scopus 로고    scopus 로고
    • Oscillating fluid flow activation of gap junction hemichannels induces atp release from mlo-y4 osteocytes
    • Genetos, D. C., Kephart, C. J., Zhang, Y., Yellowley, C. E., and Donahue, H. J. (2007) Oscillating fluid flow activation of gap junction hemichannels induces ATP release from MLO-Y4 osteocytes. J. Cell. Physiol. 212, 207-214
    • (2007) J. Cell. Physiol. , vol.212 , pp. 207-214
    • Genetos, D.C.1    Kephart, C.J.2    Zhang, Y.3    Yellowley, C.E.4    Donahue, H.J.5
  • 56
    • 30044443068 scopus 로고    scopus 로고
    • The p2x7 nucleotide receptor mediates skeletal mechanotransduction
    • Li, J., Liu, D., Ke, H. Z., Duncan, R. L., and Turner, C. H. (2005) The P2X7 nucleotide receptor mediates skeletal mechanotransduction. J. Biol. Chem. 280, 42952-42959
    • (2005) J. Biol. Chem. , vol.280 , pp. 42952-42959
    • Li, J.1    Liu, D.2    Ke, H.Z.3    Duncan, R.L.4    Turner, C.H.5
  • 59
    • 84870388520 scopus 로고    scopus 로고
    • Enhanced periosteal and endocortical responses to axial tibial compression loading in conditional connexin43 deficient mice
    • Grimston, S. K., Watkins, M. P., Brodt, M. D., Silva, M. J., and Civitelli, R. (2012) Enhanced periosteal and endocortical responses to axial tibial compression loading in conditional connexin43 deficient mice. PLoS One 7, e44222
    • (2012) PLoS One , vol.7
    • Grimston, S.K.1    Watkins, M.P.2    Brodt, M.D.3    Silva, M.J.4    Civitelli, R.5
  • 60
    • 84866032039 scopus 로고    scopus 로고
    • Connexin43 and pannexin1 channels in osteoblasts: Who is the "hemichannel"?
    • Thi, M. M., Islam, S., Suadicani, S. O., and Spray, D. C. (2012) Connexin43 and pannexin1 channels in osteoblasts: who is the "hemichannel"? J. Membr. Biol. 245, 401-409
    • (2012) J. Membr. Biol. , vol.245 , pp. 401-409
    • Thi, M.M.1    Islam, S.2    Suadicani, S.O.3    Spray, D.C.4


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