A Voltage-Gated Calcium Channel Regulates Lysosomal Fusion with Endosomes and Autophagosomes and Is Required for Neuronal Homeostasis

PLoS Biology

Volumn 13, Issue 3, 2015, Pages

  Tian, Xuejun ^a   Gala, Upasana ^b   Zhang, Yongping ^a   Shang, Weina ^a   Nagarkar Jaiswal, Sonal ^b   di Ronza, Alberto ^b,c   Jaiswal, Manish ^b   Yamamoto, Shinya ^b,c   Sandoval, Hector ^b,c   Duraine, Lita ^b   Sardiello, Marco ^b,c   Sillitoe, Roy V ^b,c   Venkatachalam, Kartik ^b,d   Fan, Hengyu ^a   Bellen, Hugo J ^b,c   Tong, Chao ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c TEXAS CHILDREN S HOSPITAL   (United States)

^d UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VOLTAGE GATED CALCIUM CHANNEL; CAC PROTEIN, DROSOPHILA; CACNA2D2 PROTEIN, MOUSE; CALCIUM; CALCIUM CHANNEL; CALCIUM CHANNEL N TYPE; DROSOPHILA PROTEIN; STJ PROTEIN, DROSOPHILA; VOLTAGE-DEPENDENT CALCIUM CHANNEL (P-Q TYPE);

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATAXIA; AUTOPHAGOSOME; AUTOPHAGY; CAC GENE; CACNA1A GENE; CACNA2D2 GENE; CELL VACUOLE; CEREBELLUM; CONTROLLED STUDY; DROSOPHILA; ENDOSOME; FEMALE; GENE; GENE LOSS; HOMEOSTASIS; LYSOSOME; MALE; MOTOR DYSFUNCTION; MOUSE; MUTANT; NERVE CELL; NERVE CELL CULTURE; NERVE ENDING; NONHUMAN; PHENOTYPE; PHOTORECEPTOR CELL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SYNAPTIC TRANSMISSION; ANIMAL; C57BL MOUSE; CYTOLOGY; DEFICIENCY; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; MEMBRANE FUSION; METABOLISM; PHAGOSOME; PRIMARY CELL CULTURE; SYNAPSE VESICLE; ULTRASTRUCTURE;

MUS;

ANIMALS; AUTOPHAGY; CALCIUM; CALCIUM CHANNELS; CALCIUM CHANNELS, N-TYPE; CEREBELLUM; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ENDOSOMES; FEMALE; GENE EXPRESSION REGULATION; HOMEOSTASIS; LYSOSOMES; MALE; MEMBRANE FUSION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; PHAGOSOMES; PRIMARY CELL CULTURE; SYNAPTIC TRANSMISSION; SYNAPTIC VESICLES;

EID: 84926382243     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1002103     Document Type: Article

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