Methods to measure cytoplasmic and mitochondrial Ca2+ concentration using Ca2+-sensitive dyes

Methods in Enzymology

Volumn 543, Issue , 2014, Pages 1-20

  Srikanth, Sonal ^a   Kim, Kyun Do ^a   Gwack, Yousang ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

CRAC channel; Fura 2; Orai; Rhod 2; STIM; T cells

Indexed keywords

CD4 ANTIGEN; DYE; FURA 2; REAGENT; AEQUORIN; CALCIUM; COLORING AGENT;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL DIFFERENTIATION; CELL ISOLATION; CYTOPLASM; EFFECTOR CELL; LYMPH NODE; MITOCHONDRION; PRIORITY JOURNAL; SINGLE CELL ANALYSIS; SPLEEN; T LYMPHOCYTE; ANIMAL; CELL COMPARTMENTALIZATION; DRUG EFFECTS; HUMAN; METABOLISM; MOUSE; TRANSGENIC MOUSE; TUMOR CELL LINE;

AEQUORIN; ANIMALS; CALCIUM; CELL COMPARTMENTATION; CELL LINE, TUMOR; COLORING AGENTS; CYTOPLASM; HUMANS; MICE; MICE, TRANSGENIC; MITOCHONDRIA;

EID: 84902179545     PISSN: 00766879     EISSN: 15577988     Source Type: Book Series    
DOI: 10.1016/B978-0-12-801329-8.00001-5     Document Type: Chapter

References (51)

1. J.M. Baughman, F. Perocchi, H.S. Girgis, M. Plovanich, C.A. Belcher-Timme, and Y. Sancak et al. Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter Nature 476 7360 2011 341 345
2. O. Brandman, J. Liou, W.S. Park, and T. Meyer STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2 + levels Cell 131 7 2007 1327 1339
3. R.C. Budd Activation-induced cell death Current Opinion in Immunology 13 3 2001 356 362
4. M.D. Cahalan STIMulating store-operated Ca(2 +) entry Nature Cell Biology 11 6 2009 669 677
5. M.D. Cahalan, and K.G. Chandy The functional network of ion channels in T lymphocytes Immunological Reviews 231 1 2009 59 87
6. Y.F. Chen, W.T. Chiu, Y.T. Chen, P.Y. Lin, H.J. Huang, and C.Y. Chou et al. Calcium store sensor stromal-interaction molecule 1-dependent signaling plays an important role in cervical cancer growth, migration, and angiogenesis Proceedings of the National Academy of Sciences of the United States of America 108 2011 15225 15230
7. H.E. Collins, X. Zhu-Mauldin, R.B. Marchase, and J.C. Chatham STIM1/Orai1-mediated SOCE: Current perspectives and potential roles in cardiac function and pathology American Journal of Physiology. Heart and Circulatory Physiology 305 4 2013 H446 H458
8. W.I. Dehaven, J.T. Smyth, R.R. Boyles, G.S. Bird, and J.W. Putney Jr. Complex actions of 2-aminoethyldiphenyl borate on store-operated calcium entry Journal of Biological Chemistry 283 28 2008 19265 19273
9. D. De Stefani, A. Raffaello, E. Teardo, I. Szabo, and R. Rizzuto A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter Nature 476 7360 2011 336 340
10. M. Feng, D.M. Grice, H.M. Faddy, N. Nguyen, S. Leitch, and Y. Wang et al. Store-independent activation of Orai1 by SPCA2 in mammary tumors Cell 143 1 2010 84 98
11. S. Feske, Y. Gwack, M. Prakriya, S. Srikanth, S.H. Puppel, and B. Tanasa et al. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function Nature 441 7090 2006 179 185
12. R.I. Fonteriz, S. de la Fuente, A. Moreno, C.D. Lobaton, M. Montero, and J. Alvarez Monitoring mitochondrial [Ca(2 +)] dynamics with rhod-2, ratiometric pericam and aequorin Cell Calcium 48 1 2010 61 69
13. G. Grynkiewicz, M. Poenie, and R.Y. Tsien A new generation of Ca2 + indicators with greatly improved fluorescence properties Journal of Biological Chemistry 260 6 1985 3440 3450
14. Y. Gwack, S. Srikanth, S. Feske, F. Cruz-Guilloty, M. Oh-hora, and D.S. Neems et al. Biochemical and functional characterization of Orai proteins Journal of Biological Chemistry 282 22 2007 16232 16243
15. Y. Gwack, S. Srikanth, M. Oh-Hora, P.G. Hogan, E.D. Lamperti, and M. Yamashita et al. Hair loss and defective T and B cell function in mice lacking ORAI1 Molecular and Cellular Biology 28 17 2008 5209 5222
16. D. Hildeman, T. Jorgensen, J. Kappler, and P. Marrack Apoptosis and the homeostatic control of immune responses Current Opinion in Immunology 19 5 2007 516 521
17. D.A. Hildeman, Y. Zhu, T.C. Mitchell, P. Bouillet, A. Strasser, and J. Kappler et al. Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim Immunity 16 6 2002 759 767
18. M.R. Hodge, A.M. Ranger, F. Charles de la Brousse, T. Hoey, M.J. Grusby, and L.H. Glimcher Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice Immunity 4 4 1996 397 405
19. P.G. Hogan, R.S. Lewis, and A. Rao Molecular basis of calcium signaling in lymphocytes: STIM and ORAI Annual Review of Immunology 28 2010 491 533
20. K.D. Kim, S. Srikanth, M.K. Yee, D.C. Mock, G.W. Lawson, and Y. Gwack ORAI1 deficiency impairs activated T cell death and enhances T cell survival Journal of Immunology 187 7 2011 3620 3630
21. P.H. Krammer, R. Arnold, and I.N. Lavrik Life and death in peripheral T cells Nature Reviews. Immunology 7 7 2007 532 542
22. R.S. Lewis Store-operated calcium channels: New perspectives on mechanism and function Cold Spring Harbor Perspectives in Biology 3 12 2011 a003970
23. J. Liou, M.L. Kim, W.D. Heo, J.T. Jones, J.W. Myers, and J.E. Ferrell Jr. et al. STIM is a Ca2 + sensor essential for Ca2+-store-depletion-triggered Ca2 + influx Current Biology 15 13 2005 1235 1241
24. F. Macian, F. Garcia-Cozar, S.H. Im, H.F. Horton, M.C. Byrne, and A. Rao Transcriptional mechanisms underlying lymphocyte tolerance Cell 109 6 2002 719 731
25. P. Marrack, and J. Kappler Control of T cell viability Annual Review of Immunology 22 2004 765 787
26. V.S. Marsden, and A. Strasser Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more Annual Review of Immunology 21 2003 71 105
27. M.P. Matheu, I. Parker, and M.D. Cahalan Dissection and 2-photon imaging of peripheral lymph nodes in mice Journal of Visualized Experiments 7 2007 265
28. M. Oh-Hora, M. Yamashita, P.G. Hogan, S. Sharma, E. Lamperti, and W. Chung et al. Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance Nature Immunology 9 4 2008 432 443
29. C. Peinelt, A. Lis, A. Beck, A. Fleig, and R. Penner 2- Aminoethoxydiphenyl borate directly facilitates and indirectly inhibits STIM1-dependent gating of CRAC channels Journal of Physiology 586 13 2008 3061 3073
30. M. Prakriya, and R.S. Lewis Potentiation and inhibition of Ca(2 +) release-activated Ca(2 +) channels by 2-aminoethyldiphenyl borate (2-APB) occurs independently of IP(3) receptors Journal of Physiology 536 Pt 1 2001 3 19
31. N. Prevarskaya, R. Skryma, and Y. Shuba Calcium in tumour metastasis: New roles for known actors Nature Reviews. Cancer 11 8 2011 609 618
32. J.W. Putney Jr. A model for receptor-regulated calcium entry Cell Calcium 7 1 1986 1 12
33. A. Quintana, M. Pasche, C. Junker, D. Al-Ansary, H. Rieger, and C. Kummerow et al. Calcium microdomains at the immunological synapse: How ORAI channels, mitochondria and calcium pumps generate local calcium signals for efficient T-cell activation EMBO Journal 30 19 2011 3895 3912
34. A. Quintana, C. Schwindling, A.S. Wenning, U. Becherer, J. Rettig, and E.C. Schwarz et al. T cell activation requires mitochondrial translocation to the immunological synapse Proceedings of the National Academy of Sciences of the United States of America 104 36 2007 14418 14423
35. J. Roos, P.J. DiGregorio, A.V. Yeromin, K. Ohlsen, M. Lioudyno, and S. Zhang et al. STIM1, an essential and conserved component of store-operated Ca2 + channel function Journal of Cell Biology 169 3 2005 435 445
36. R. Schindl, J. Bergsmann, I. Frischauf, I. Derler, M. Fahrner, and M. Muik et al. 2-Aminoethoxydiphenyl borate alters selectivity of orai3 channels by increasing their pore size Journal of Biological Chemistry 283 29 2008 20261 20267
37. E. Serfling, S. Klein-Hessling, A. Palmetshofer, T. Bopp, M. Stassen, and E. Schmitt NFAT transcription factors in control of peripheral T cell tolerance European Journal of Immunology 36 11 2006 2837 2843
38. J. Soboloff, B.S. Rothberg, M. Madesh, and D.L. Gill STIM proteins: Dynamic calcium signal transducers Nature Reviews. Molecular Cell Biology 13 9 2012 549 565
39. S. Srikanth, and Y. Gwack Measurement of intracellular Ca2 + concentration in single cells using ratiometric calcium dyes Methods in Molecular Biology 963 2013 3 14
40. S. Srikanth, and Y. Gwack Orai1-NFAT signalling pathway triggered by T cell receptor stimulation Molecules and Cells 35 3 2013 182 194
41. S. Srikanth, M. Jew, K.D. Kim, M.K. Yee, J. Abramson, and Y. Gwack Junctate is a Ca2+-sensing structural component of Orai1 and stromal interaction molecule 1 (STIM1) Proceedings of the National Academy of Sciences of the United States of America 109 22 2012 8682 8687
42. S. Srikanth, H.J. Jung, K.D. Kim, P. Souda, J. Whitelegge, and Y. Gwack A novel EF-hand protein, CRACR2A, is a cytosolic Ca2 + sensor that stabilizes CRAC channels in T cells Nature Cell Biology 12 5 2010 436 446
43. J.A. Stiber, and P.B. Rosenberg The role of store-operated calcium influx in skeletal muscle signaling Cell Calcium 49 5 2011 341 349
44. A. Strasser The role of BH3-only proteins in the immune system Nature Reviews. Immunology 5 3 2005 189 200
45. A. Strasser, and M. Pellegrini T-lymphocyte death during shutdown of an immune response Trends in Immunology 25 11 2004 610 615
46. M. Trebak STIM/Orai signalling complexes in vascular smooth muscle Journal of Physiology 590 Pt 17 2012 4201 4208
47. M. Vig, C. Peinelt, A. Beck, D.L. Koomoa, D. Rabah, and M. Koblan-Huberson et al. CRACM1 is a plasma membrane protein essential for store-operated Ca2 + entry Science 312 5777 2006 1220 1223
48. M. Yamashita, A. Somasundaram, and M. Prakriya Competitive modulation of Ca2 + release-activated Ca2 + channel gating by STIM1 and 2-aminoethyldiphenyl borate Journal of Biological Chemistry 286 11 2011 9429 9442
49. S. Yang, J.J. Zhang, and X.Y. Huang Orai1 and STIM1 are critical for breast tumor cell migration and metastasis Cancer Cell 15 2 2009 124 134
50. S.L. Zhang, J.A. Kozak, W. Jiang, A.V. Yeromin, J. Chen, and Y. Yu et al. Store-dependent and -independent modes regulating Ca2 + release-activated Ca2 + channel activity of human Orai1 and Orai3 Journal of Biological Chemistry 283 25 2008 17662 17671
51. S.L. Zhang, A.V. Yeromin, X.H. Zhang, Y. Yu, O. Safrina, and A. Penna et al. Genome-wide RNAi screen of Ca(2 +) influx identifies genes that regulate Ca(2 +) release-activated Ca(2 +) channel activity Proceedings of the National Academy of Sciences of the United States of America 103 24 2006 9357 9362