-
1
-
-
56349166514
-
Mechanisms of microglia accumulation in Alzheimer's disease: therapeutic implications
-
El Khoury, J. and Luster, A.D. (2008) Mechanisms of microglia accumulation in Alzheimer's disease: therapeutic implications. Trends Pharmacol. Sci., 29, 626-632.
-
(2008)
Trends Pharmacol. Sci
, vol.29
, pp. 626-632
-
-
El Khoury, J.1
Luster, A.D.2
-
2
-
-
17144403821
-
Retinoic acid inhibits expression of TNF-alpha and iNOS in activated rat microglia
-
Dheen, S.T., Jun, Y., Yan, Z., Tay, S.S. and Ling, E.A. (2005) Retinoic acid inhibits expression of TNF-alpha and iNOS in activated rat microglia. Glia, 50, 21-31.
-
(2005)
Glia
, vol.50
, pp. 21-31
-
-
Dheen, S.T.1
Jun, Y.2
Yan, Z.3
Tay, S.S.4
Ling, E.A.5
-
3
-
-
70349807619
-
Immune activation in brain aging and neurodegeneration: too much or too little?
-
Lucin, K.M. and Wyss-Coray, T. (2009) Immune activation in brain aging and neurodegeneration: too much or too little? Neuron, 64, 110-122.
-
(2009)
Neuron
, vol.64
, pp. 110-122
-
-
Lucin, K.M.1
Wyss-Coray, T.2
-
4
-
-
77950363010
-
Mechanisms underlying inflammation in neurodegeneration
-
Glass, C.K., Saijo, K., Winner, B., Marchetto, M.C. and Gage, F.H. (2010) Mechanisms underlying inflammation in neurodegeneration. Cell, 140, 918-934.
-
(2010)
Cell
, vol.140
, pp. 918-934
-
-
Glass, C.K.1
Saijo, K.2
Winner, B.3
Marchetto, M.C.4
Gage, F.H.5
-
5
-
-
34147115541
-
Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease
-
El Khoury, J., Toft, M., Hickman, S.E., Means, T.K., Terada, K., Geula, C. and Luster, A.D. (2007) Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease. Nat. Med., 13, 432-438.
-
(2007)
Nat. Med
, vol.13
, pp. 432-438
-
-
El Khoury, J.1
Toft, M.2
Hickman, S.E.3
Means, T.K.4
Terada, K.5
Geula, C.6
Luster, A.D.7
-
6
-
-
0037394788
-
Adult mouse astrocytes degrade amyloid-beta in vitro and in situ
-
Wyss-Coray, T., Loike, J.D., Brionne, T.C., Lu, E., Anankov, R., Yan, F., Silverstein, S.C. and Husemann, J. (2003) Adult mouse astrocytes degrade amyloid-beta in vitro and in situ. Nat. Med., 9, 453-457.
-
(2003)
Nat. Med
, vol.9
, pp. 453-457
-
-
Wyss-Coray, T.1
Loike, J.D.2
Brionne, T.C.3
Lu, E.4
Anankov, R.5
Yan, F.6
Silverstein, S.C.7
Husemann, J.8
-
7
-
-
2542431100
-
The microglial phagocytic role with specific plaque types in the Alzheimer disease brain
-
D'Andrea, M.R., Cole, G.M. and Ard, M.D. (2004) The microglial phagocytic role with specific plaque types in the Alzheimer disease brain. Neurobiol. Aging, 25, 675-683.
-
(2004)
Neurobiol. Aging
, vol.25
, pp. 675-683
-
-
D'Andrea, M.R.1
Cole, G.M.2
Ard, M.D.3
-
8
-
-
0031983986
-
Glial-neuronal interactions in Alzheimer's disease: the potential role of a 'cytokine cycle' in disease progression
-
Griffin, W.S., Sheng, J.G., Royston, M.C., Gentleman, S.M., McKenzie, J.E., Graham, D.I., Roberts, G.W. and Mrak, R.E. (1998) Glial-neuronal interactions in Alzheimer's disease: the potential role of a 'cytokine cycle' in disease progression. Brain Pathol., 8, 65-72.
-
(1998)
Brain Pathol
, vol.8
, pp. 65-72
-
-
Griffin, W.S.1
Sheng, J.G.2
Royston, M.C.3
Gentleman, S.M.4
McKenzie, J.E.5
Graham, D.I.6
Roberts, G.W.7
Mrak, R.E.8
-
9
-
-
35148863154
-
Inflammatory changes parallel the early stages of Alzheimer disease
-
Parachikova, A., Agadjanyan, M.G., Cribbs, D.H., Blurton-Jones, M., Perreau, V., Rogers, J., Beach, T.G. and Cotman, C.W. (2007) Inflammatory changes parallel the early stages of Alzheimer disease. Neurobiol. Aging, 28, 1821-1833.
-
(2007)
Neurobiol. Aging
, vol.28
, pp. 1821-1833
-
-
Parachikova, A.1
Agadjanyan, M.G.2
Cribbs, D.H.3
Blurton-Jones, M.4
Perreau, V.5
Rogers, J.6
Beach, T.G.7
Cotman, C.W.8
-
10
-
-
63049083734
-
A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death
-
Saijo, K., Winner, B., Carson, C.T., Collier, J.G., Boyer, L., Rosenfeld, M.G., Gage, F.H. and Glass, C.K. (2009) A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death. Cell, 137, 47-59.
-
(2009)
Cell
, vol.137
, pp. 47-59
-
-
Saijo, K.1
Winner, B.2
Carson, C.T.3
Collier, J.G.4
Boyer, L.5
Rosenfeld, M.G.6
Gage, F.H.7
Glass, C.K.8
-
11
-
-
84866148510
-
Calcium Signaling and Gliotransmission in Normal versus Reactive Astrocytes
-
Agulhon, C., Sun, M.Y., Murphy, T., Myers, T., Lauderdale, K. and Fiacco, T.A. (2012) Calcium Signaling and Gliotransmission in Normal versus Reactive Astrocytes. Front. Pharmacol., 3, 139.
-
(2012)
Front. Pharmacol
, vol.3
, pp. 139
-
-
Agulhon, C.1
Sun, M.Y.2
Murphy, T.3
Myers, T.4
Lauderdale, K.5
Fiacco, T.A.6
-
12
-
-
33847613885
-
Inflammatory processes in Alzheimer's disease
-
Heneka, M.T. and O'Banion, M.K. (2007) Inflammatory processes in Alzheimer's disease. J. Neuroimmunol., 184, 69-91.
-
(2007)
J. Neuroimmunol
, vol.184
, pp. 69-91
-
-
Heneka, M.T.1
O'Banion, M.K.2
-
13
-
-
35848963223
-
Role of the toll-like receptor 4 in neuroinflammation in Alzheimer's disease
-
Walter, S., Letiembre, M., Liu, Y., Heine, H., Penke, B., Hao, W., Bode, B., Manietta, N., Walter, J., Schulz-Schuffer, W. et al. (2007) Role of the toll-like receptor 4 in neuroinflammation in Alzheimer's disease. Cell Physiol. Biochem., 20, 947-956.
-
(2007)
Cell Physiol. Biochem
, vol.20
, pp. 947-956
-
-
Walter, S.1
Letiembre, M.2
Liu, Y.3
Heine, H.4
Penke, B.5
Hao, W.6
Bode, B.7
Manietta, N.8
Walter, J.9
Schulz-Schuffer, W.10
-
14
-
-
62349114515
-
Screening of innate immune receptors in neurodegenerative diseases: a similar pattern
-
Letiembre, M., Liu, Y., Walter, S., Hao, W., Pfander, T., Wrede, A., Schulz-Schaeffer, W. and Fassbender, K. (2009) Screening of innate immune receptors in neurodegenerative diseases: a similar pattern. Neurobiol. Aging, 30, 759-768.
-
(2009)
Neurobiol. Aging
, vol.30
, pp. 759-768
-
-
Letiembre, M.1
Liu, Y.2
Walter, S.3
Hao, W.4
Pfander, T.5
Wrede, A.6
Schulz-Schaeffer, W.7
Fassbender, K.8
-
15
-
-
75649087741
-
CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
-
Stewart, C.R., Stuart, L.M., Wilkinson, K., van Gils, J.M., Deng, J., Halle, A., Rayner, K.J., Boyer, L., Zhong, R., Frazier, W.A. et al. (2010) CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer. Nat. Immunol., 11, 155-161.
-
(2010)
Nat. Immunol
, vol.11
, pp. 155-161
-
-
Stewart, C.R.1
Stuart, L.M.2
Wilkinson, K.3
van Gils, J.M.4
Deng, J.5
Halle, A.6
Rayner, K.J.7
Boyer, L.8
Zhong, R.9
Frazier, W.A.10
-
16
-
-
78650250592
-
Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFkappaB signaling, MAPK, and Jak1/Stat1 pathways
-
Gorina, R., Font-Nieves, M., Marquez-Kisinousky, L., Santalucia, T. and Planas, A.M. (2011) Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFkappaB signaling, MAPK, and Jak1/Stat1 pathways. Glia, 59, 242-255.
-
(2011)
Glia
, vol.59
, pp. 242-255
-
-
Gorina, R.1
Font-Nieves, M.2
Marquez-Kisinousky, L.3
Santalucia, T.4
Planas, A.M.5
-
17
-
-
49349097868
-
Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid beta-peptide and the membrane lipid peroxidation product 4-hydroxynonenal
-
Tang, S.C., Lathia, J.D., Selvaraj, P.K., Jo, D.G., Mughal, M.R., Cheng, A., Siler, D.A., Markesbery, W.R., Arumugam, T.V. and Mattson, M.P. (2008) Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid beta-peptide and the membrane lipid peroxidation product 4-hydroxynonenal. Exp. Neurol., 213, 114-121.
-
(2008)
Exp. Neurol
, vol.213
, pp. 114-121
-
-
Tang, S.C.1
Lathia, J.D.2
Selvaraj, P.K.3
Jo, D.G.4
Mughal, M.R.5
Cheng, A.6
Siler, D.A.7
Markesbery, W.R.8
Arumugam, T.V.9
Mattson, M.P.10
-
18
-
-
84870351750
-
Indomethacin-loaded lipid-core nanocapsules reduce the damage triggered by Abeta1-42 in Alzheimer's disease models
-
Bernardi, A., Frozza, R.L., Meneghetti, A., Hoppe, J.B., Battastini, A.M., Pohlmann, A.R., Guterres, S.S. and Salbego, C.G. (2012) Indomethacin-loaded lipid-core nanocapsules reduce the damage triggered by Abeta1-42 in Alzheimer's disease models. Int. J. Nanomed., 7, 4927-4942.
-
(2012)
Int. J. Nanomed
, vol.7
, pp. 4927-4942
-
-
Bernardi, A.1
Frozza, R.L.2
Meneghetti, A.3
Hoppe, J.B.4
Battastini, A.M.5
Pohlmann, A.R.6
Guterres, S.S.7
Salbego, C.G.8
-
19
-
-
62249200515
-
Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway
-
Vukic, V., Callaghan, D., Walker, D., Lue, L.F., Liu, Q.Y., Couraud, P.O., Romero, I.A., Weksler, B., Stanimirovic, D.B. and Zhang, W. (2009) Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway. Neurobiol. Dis., 34, 95-106.
-
(2009)
Neurobiol. Dis
, vol.34
, pp. 95-106
-
-
Vukic, V.1
Callaghan, D.2
Walker, D.3
Lue, L.F.4
Liu, Q.Y.5
Couraud, P.O.6
Romero, I.A.7
Weksler, B.8
Stanimirovic, D.B.9
Zhang, W.10
-
20
-
-
77349098528
-
Tf-lipoplex-mediated c-Jun silencing improves neuronal survival following excitotoxic damage in vivo
-
Cardoso, A.L., Costa, P., de Almeida, L.P., Simoes, S., Plesnila, N., Culmsee, C., Wagner, E. and de Lima, M.C. (2010) Tf-lipoplex-mediated c-Jun silencing improves neuronal survival following excitotoxic damage in vivo. J. Control. Release, 142, 392-403.
-
(2010)
J. Control. Release
, vol.142
, pp. 392-403
-
-
Cardoso, A.L.1
Costa, P.2
de Almeida, L.P.3
Simoes, S.4
Plesnila, N.5
Culmsee, C.6
Wagner, E.7
de Lima, M.C.8
-
21
-
-
57649119790
-
An NF-kappaB-sensitive micro RNA-146a-mediated inflammatory circuit in Alzheimer disease and in stressed human brain cells
-
Lukiw, W.J., Zhao, Y. and Cui, J.G. (2008) An NF-kappaB-sensitive micro RNA-146a-mediated inflammatory circuit in Alzheimer disease and in stressed human brain cells. J. Biol. Chem., 283, 31315-31322.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 31315-31322
-
-
Lukiw, W.J.1
Zhao, Y.2
Cui, J.G.3
-
22
-
-
47849124269
-
Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways
-
Cogswell, J.P., Ward, J., Taylor, I.A., Waters, M., Shi, Y., Cannon, B., Kelnar, K., Kemppainen, J., Brown, D., Chen, C. et al. (2008) Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways. J. Alzheimers Dis., 14, 27-41.
-
(2008)
J. Alzheimers Dis
, vol.14
, pp. 27-41
-
-
Cogswell, J.P.1
Ward, J.2
Taylor, I.A.3
Waters, M.4
Shi, Y.5
Cannon, B.6
Kelnar, K.7
Kemppainen, J.8
Brown, D.9
Chen, C.10
-
23
-
-
79959379335
-
Differential expression of miRNA-146a-regulated inflammatory genes in human primary neural, astroglial and microglial cells
-
Li, Y.Y., Cui, J.G., Dua, P., Pogue, A.I., Bhattacharjee, S. and Lukiw, W.J. (2011) Differential expression of miRNA-146a-regulated inflammatory genes in human primary neural, astroglial and microglial cells. Neurosci. Lett., 499, 109-113.
-
(2011)
Neurosci. Lett
, vol.499
, pp. 109-113
-
-
Li, Y.Y.1
Cui, J.G.2
Dua, P.3
Pogue, A.I.4
Bhattacharjee, S.5
Lukiw, W.J.6
-
24
-
-
34247594818
-
Regulation of the germinal center response by microRNA-155
-
Thai, T.H., Calado, D.P., Casola, S., Ansel, K.M., Xiao, C., Xue, Y., Murphy, A., Frendewey, D., Valenzuela, D., Kutok, J.L. et al. (2007) Regulation of the germinal center response by microRNA-155. Science, 316, 604-608.
-
(2007)
Science
, vol.316
, pp. 604-608
-
-
Thai, T.H.1
Calado, D.P.2
Casola, S.3
Ansel, K.M.4
Xiao, C.5
Xue, Y.6
Murphy, A.7
Frendewey, D.8
Valenzuela, D.9
Kutok, J.L.10
-
25
-
-
83055176904
-
miR-155 modulates microglia-mediated immune response by down-regulating SOCS-1 and promoting cytokine and nitric oxide production
-
Cardoso, A.L., Guedes, J.R., Pereira de Almeida, L. and Pedroso de Lima, M.C. (2012) miR-155 modulates microglia-mediated immune response by down-regulating SOCS-1 and promoting cytokine and nitric oxide production. Immunology, 135, 73-88.
-
(2012)
Immunology
, vol.135
, pp. 73-88
-
-
Cardoso, A.L.1
Guedes, J.R.2
Pereira de Almeida, L.3
Pedroso de Lima, M.C.4
-
26
-
-
84878648745
-
Involvement of microRNA in microglia-mediated immune response
-
Guedes, J., Cardoso, A.L. and Pedroso de Lima, M.C. (2013) Involvement of microRNA in microglia-mediated immune response. Clin. Dev. Immunol., 2013, 186872.
-
(2013)
Clin. Dev. Immunol
, vol.2013
-
-
Guedes, J.1
Cardoso, A.L.2
Pedroso de Lima, M.C.3
-
27
-
-
33846845071
-
MicroRNA-155 is induced during the macrophage inflammatory response
-
O'Connell, R.M., Taganov, K.D., Boldin, M.P., Cheng, G. and Baltimore, D. (2007) MicroRNA-155 is induced during the macrophage inflammatory response. Proc. Natl. Acad. Sci. USA, 104, 1604-1609.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 1604-1609
-
-
O'Connell, R.M.1
Taganov, K.D.2
Boldin, M.P.3
Cheng, G.4
Baltimore, D.5
-
28
-
-
84879880601
-
S100P/RAGE signaling regulates microRNA-155 expression via AP-1 activation in colon cancer
-
Onyeagucha, B.C., Mercado-Pimentel, M.E., Hutchison, J., Flemington, E.K. and Nelson, M.A. (2013) S100P/RAGE signaling regulates microRNA-155 expression via AP-1 activation in colon cancer. Exp. Cell Res., 319, 2081-2090.
-
(2013)
Exp. Cell Res
, vol.319
, pp. 2081-2090
-
-
Onyeagucha, B.C.1
Mercado-Pimentel, M.E.2
Hutchison, J.3
Flemington, E.K.4
Nelson, M.A.5
-
29
-
-
79956014029
-
Species-specific microRNA roles elucidated following astrocyte activation
-
Mor, E., Cabilly, Y., Goldshmit, Y., Zalts, H., Modai, S., Edry, L., Elroy-Stein, O. and Shomron, N. (2011) Species-specific microRNA roles elucidated following astrocyte activation. Nucleic Acids Res., 39, 3710-3723.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 3710-3723
-
-
Mor, E.1
Cabilly, Y.2
Goldshmit, Y.3
Zalts, H.4
Modai, S.5
Edry, L.6
Elroy-Stein, O.7
Shomron, N.8
-
30
-
-
84874664922
-
Anti-viral and anti-inflammatory mechanisms of the innate immune transcription factor interferon regulatory factor 3: relevance to human CNS diseases
-
Tarassishin, L., Bauman, A., Suh, H.S. and Lee, S.C. (2012) Anti-viral and anti-inflammatory mechanisms of the innate immune transcription factor interferon regulatory factor 3: relevance to human CNS diseases. J. Neuroimmune Pharmacol., 8, 132-144.
-
(2012)
J. Neuroimmune Pharmacol
, vol.8
, pp. 132-144
-
-
Tarassishin, L.1
Bauman, A.2
Suh, H.S.3
Lee, S.C.4
-
32
-
-
0344845132
-
Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease
-
Oddo, S., Caccamo, A., Kitazawa, M., Tseng, B.P. and LaFerla, F.M. (2003) Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease. Neurobiol. Aging, 24, 1063-1070.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 1063-1070
-
-
Oddo, S.1
Caccamo, A.2
Kitazawa, M.3
Tseng, B.P.4
LaFerla, F.M.5
-
33
-
-
27744482552
-
Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice
-
Janelsins, M.C., Mastrangelo, M.A., Oddo, S., LaFerla, F.M., Federoff, H.J. and Bowers, W.J. (2005) Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice. J. Neuroinflammation, 2, 23.
-
(2005)
J. Neuroinflammation
, vol.2
, pp. 23
-
-
Janelsins, M.C.1
Mastrangelo, M.A.2
Oddo, S.3
LaFerla, F.M.4
Federoff, H.J.5
Bowers, W.J.6
-
34
-
-
57149101898
-
Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice
-
Janelsins, M.C., Mastrangelo, M.A., Park, K.M., Sudol, K.L., Narrow, W.C., Oddo, S., LaFerla, F.M., Callahan, L.M., Federoff, H.J. and Bowers, W.J. (2008) Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice. Am. J. Pathol., 173, 1768-1782.
-
(2008)
Am. J. Pathol
, vol.173
, pp. 1768-1782
-
-
Janelsins, M.C.1
Mastrangelo, M.A.2
Park, K.M.3
Sudol, K.L.4
Narrow, W.C.5
Oddo, S.6
LaFerla, F.M.7
Callahan, L.M.8
Federoff, H.J.9
Bowers, W.J.10
-
35
-
-
10744227105
-
Hippocampus and entorhinal cortex in mild cognitive impairment and early AD
-
Pennanen, C., Kivipelto, M., Tuomainen, S., Hartikainen, P., Hanninen, T., Laakso, M.P., Hallikainen, M., Vanhanen, M., Nissinen, A., Helkala, E.L. et al. (2004) Hippocampus and entorhinal cortex in mild cognitive impairment and early AD. Neurobiol. Aging, 25, 303-310.
-
(2004)
Neurobiol. Aging
, vol.25
, pp. 303-310
-
-
Pennanen, C.1
Kivipelto, M.2
Tuomainen, S.3
Hartikainen, P.4
Hanninen, T.5
Laakso, M.P.6
Hallikainen, M.7
Vanhanen, M.8
Nissinen, A.9
Helkala, E.L.10
-
36
-
-
38049030287
-
Modulation of miR-155 and miR-125b Levels following Lipopolysaccharide/TNF-Stimulation and Their possible roles in regulating the response to endotoxin shock
-
Tili, E., Michaille, J.J., Cimino, A., Costinean, S., Dumitru, C.D., Adair, B., Fabbri, M., Alder, H., Liu, C.G., Calin, G.A. et al. (2007) Modulation of miR-155 and miR-125b Levels following Lipopolysaccharide/TNF-Stimulation and Their possible roles in regulating the response to endotoxin shock. J. Immunol., 15, 5082-5089.
-
(2007)
J. Immunol
, vol.15
, pp. 5082-5089
-
-
Tili, E.1
Michaille, J.J.2
Cimino, A.3
Costinean, S.4
Dumitru, C.D.5
Adair, B.6
Fabbri, M.7
Alder, H.8
Liu, C.G.9
Calin, G.A.10
-
37
-
-
77952745811
-
Micro RNA-125b (miRNA-125b) function in astrogliosis and glial cell proliferation
-
Pogue, A.I., Cui, J.G., Li, Y.Y., Zhao, Y., Culicchia, F. and Lukiw, W.J. (2010) Micro RNA-125b (miRNA-125b) function in astrogliosis and glial cell proliferation. Neurosci. Lett., 476, 18-122.
-
(2010)
Neurosci. Lett
, vol.476
, pp. 18-122
-
-
Pogue, A.I.1
Cui, J.G.2
Li, Y.Y.3
Zhao, Y.4
Culicchia, F.5
Lukiw, W.J.6
-
38
-
-
63349094897
-
Alterations of the microRNA network cause neurodegenerative disease
-
Hebert, S.S. and De Strooper, B. (2009) Alterations of the microRNA network cause neurodegenerative disease. Trends Neurosci., 32, 199-206.
-
(2009)
Trends Neurosci
, vol.32
, pp. 199-206
-
-
Hebert, S.S.1
De Strooper, B.2
-
39
-
-
80053466213
-
MicroRNAs and Alzheimer's disease mouse models: current insights and future research avenues
-
Delay, C. and Hebert, S.S. (2011) MicroRNAs and Alzheimer's disease mouse models: current insights and future research avenues. Int. J. Alzheimers Dis., 2011, 894938.
-
(2011)
Int. J. Alzheimers Dis
, vol.2011
-
-
Delay, C.1
Hebert, S.S.2
-
40
-
-
80053576812
-
Interferon regulatory factor 3 inhibits astrocyte inflammatory gene expression through suppression of the proinflammatory miR-155 and miR-155*
-
Tarassishin, L., Loudig, O., Bauman, A., Shafit-Zagardo, B., Suh, H.S. and Lee, S.C. (2011) Interferon regulatory factor 3 inhibits astrocyte inflammatory gene expression through suppression of the proinflammatory miR-155 and miR-155*. Glia, 59, 1911-1922.
-
(2011)
Glia
, vol.59
, pp. 1911-1922
-
-
Tarassishin, L.1
Loudig, O.2
Bauman, A.3
Shafit-Zagardo, B.4
Suh, H.S.5
Lee, S.C.6
-
41
-
-
84869171691
-
MicroRNAs are universal regulators of differentiation, activation, and polarization of microglia and macrophages in normal and diseased CNS
-
Ponomarev, E.D., Veremeyko, T. and Weiner, H.L. (2013) MicroRNAs are universal regulators of differentiation, activation, and polarization of microglia and macrophages in normal and diseased CNS. Glia, 61, 91-103.
-
(2013)
Glia
, vol.61
, pp. 91-103
-
-
Ponomarev, E.D.1
Veremeyko, T.2
Weiner, H.L.3
-
42
-
-
84867584246
-
MicroRNA-155 modulates Treg and Th17 cells differentiation and Th17 cell function by targeting SOCS1
-
Yao, R., Ma, Y.L., Liang, W., Li, H.H., Ma, Z.J., Yu, X. and Liao, Y.H. (2012) MicroRNA-155 modulates Treg and Th17 cells differentiation and Th17 cell function by targeting SOCS1. PLoS One, 7, e46082.
-
(2012)
PLoS One
, vol.7
-
-
Yao, R.1
Ma, Y.L.2
Liang, W.3
Li, H.H.4
Ma, Z.J.5
Yu, X.6
Liao, Y.H.7
-
43
-
-
34249660614
-
SOCS proteins, cytokine signalling and immune regulation
-
Yoshimura, A., Naka, T. and Kubo, M. (2007) SOCS proteins, cytokine signalling and immune regulation. Nat. Rev. Immunol., 7, 454-465.
-
(2007)
Nat. Rev. Immunol
, vol.7
, pp. 454-465
-
-
Yoshimura, A.1
Naka, T.2
Kubo, M.3
-
44
-
-
68149147407
-
SOCS1andSOCS3in the control of CNS immunity
-
Baker, B.J., Akhtar, L.N. and Benveniste, E.N. (2009) SOCS1andSOCS3in the control of CNS immunity. Trends Immunol., 30, 392-400.
-
(2009)
Trends Immunol
, vol.30
, pp. 392-400
-
-
Baker, B.J.1
Akhtar, L.N.2
Benveniste, E.N.3
-
45
-
-
79958225650
-
MicroRNAs in NF-kappaB signaling
-
Ma, X., Becker Buscaglia, L.E., Barker, J.R. and Li, Y. (2011) MicroRNAs in NF-kappaB signaling. J. Mol. Cell Biol., 3, 159-166.
-
(2011)
J. Mol. Cell Biol
, vol.3
, pp. 159-166
-
-
Ma, X.1
Becker Buscaglia, L.E.2
Barker, J.R.3
Li, Y.4
-
46
-
-
78649573450
-
Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease
-
Jones, L., Holmans, P.A., Hamshere, M.L., Harold, D., Moskvina, V., Ivanov, D., Pocklington, A., Abraham, R., Hollingworth, P., Sims, R. et al. (2010) Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease. PLoS One, 5, e13950.
-
(2010)
PLoS One
, vol.5
-
-
Jones, L.1
Holmans, P.A.2
Hamshere, M.L.3
Harold, D.4
Moskvina, V.5
Ivanov, D.6
Pocklington, A.7
Abraham, R.8
Hollingworth, P.9
Sims, R.10
-
47
-
-
84873486299
-
Apathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease
-
Holmans, P., Moskvina, V., Jones, L., Sharma, M., International Parkinson's Disease Genomics Consortium, Vedernikov, A., Buchel, F., Saad, M., Bras, J.M., Bettella, F. et al. (2013) Apathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease. Hum. Mol. Genet., 22, 1039-1049.
-
(2013)
Hum. Mol. Genet
, vol.22
, pp. 1039-1049
-
-
Holmans, P.1
Moskvina, V.2
Jones, L.3
Sharma, M.4
International Parkinson's Disease Genomics Consortium Vedernikov, A.5
Buchel, F.6
Saad, M.7
Bras, J.M.8
Bettella, F.9
-
48
-
-
84872057940
-
TREM2 variants in Alzheimer's disease
-
Guerreiro, R., Wojtas, A., Bras, J., Carrasquillo, M., Rogaeva, E., Majounie, E., Cruchaga, C., Sassi, C., Kauwe, J.S., Younkin, S. et al. (2013) TREM2 variants in Alzheimer's disease. N. Engl. J. Med., 368, 117-127.
-
(2013)
N. Engl. J. Med
, vol.368
, pp. 117-127
-
-
Guerreiro, R.1
Wojtas, A.2
Bras, J.3
Carrasquillo, M.4
Rogaeva, E.5
Majounie, E.6
Cruchaga, C.7
Sassi, C.8
Kauwe, J.S.9
Younkin, S.10
-
49
-
-
35048877702
-
Peripheral inflammatory cytokines as biomarkers in Alzheimer's disease and mild cognitive impairment
-
Guerreiro, R.J., Santana, I., Bras, J.M., Santiago, B., Paiva, A. and Oliveira, C. (2007) Peripheral inflammatory cytokines as biomarkers in Alzheimer's disease and mild cognitive impairment. Neurodegener. Dis., 4, 406-412.
-
(2007)
Neurodegener. Dis
, vol.4
, pp. 406-412
-
-
Guerreiro, R.J.1
Santana, I.2
Bras, J.M.3
Santiago, B.4
Paiva, A.5
Oliveira, C.6
-
50
-
-
79956084514
-
The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
-
Albert, M.S., DeKosky, S.T., Dickson, D., Dubois, B., Feldman, H.H., Fox, N.C., Gamst, A., Holtzman, D.M., Jagust, W.J., Petersen, R.C. et al. (2011) The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement, 7, 270-279.
-
(2011)
Alzheimers Dement
, vol.7
, pp. 270-279
-
-
Albert, M.S.1
DeKosky, S.T.2
Dickson, D.3
Dubois, B.4
Feldman, H.H.5
Fox, N.C.6
Gamst, A.7
Holtzman, D.M.8
Jagust, W.J.9
Petersen, R.C.10
-
51
-
-
33748471099
-
Inflammation in Alzheimer disease: driving force, bystander or beneficial response?
-
Wyss-Coray, T. (2006) Inflammation in Alzheimer disease: driving force, bystander or beneficial response? Nat. Med., 12, 1005-1015.
-
(2006)
Nat. Med
, vol.12
, pp. 1005-1015
-
-
Wyss-Coray, T.1
-
52
-
-
66449130960
-
Regulation of innate immune responses in the brain
-
Rivest, S. (2009) Regulation of innate immune responses in the brain. Nat. Rev. Immunol., 9, 429-439.
-
(2009)
Nat. Rev. Immunol
, vol.9
, pp. 429-439
-
-
Rivest, S.1
-
53
-
-
84876006819
-
Functional impairment of microglia coincides with Beta-amyloid deposition in mice with Alzheimer-like pathology
-
Krabbe, G., Halle, A., Matyash, V., Rinnenthal, J.L., Eom, G.D., Bernhardt, U., Miller, K.R., Prokop, S., Kettenmann, H. and Heppner, F.L. (2013) Functional impairment of microglia coincides with Beta-amyloid deposition in mice with Alzheimer-like pathology. PLoS One, 8, e60921.
-
(2013)
PLoS One
, vol.8
-
-
Krabbe, G.1
Halle, A.2
Matyash, V.3
Rinnenthal, J.L.4
Eom, G.D.5
Bernhardt, U.6
Miller, K.R.7
Prokop, S.8
Kettenmann, H.9
Heppner, F.L.10
-
54
-
-
84865973639
-
The classification of microglial activation phenotypes on neurodegeneration and regeneration in Alzheimer's disease brain
-
Varnum, M.M. and Ikezu, T. (2012) The classification of microglial activation phenotypes on neurodegeneration and regeneration in Alzheimer's disease brain. Arch. Immunol. Ther. Exp. (Warsz.), 60, 251-266.
-
(2012)
Arch. Immunol. Ther. Exp. (Warsz.)
, vol.60
, pp. 251-266
-
-
Varnum, M.M.1
Ikezu, T.2
-
55
-
-
84874812665
-
Operational dissection of beta-amyloid cytopathic effects on cultured neurons
-
Callizot, N., Combes, M., Steinschneider, R. and Poindron, P. (2013) Operational dissection of beta-amyloid cytopathic effects on cultured neurons. J. Neurosci. Res., 91, 706-716.
-
(2013)
J. Neurosci. Res
, vol.91
, pp. 706-716
-
-
Callizot, N.1
Combes, M.2
Steinschneider, R.3
Poindron, P.4
-
56
-
-
0042697305
-
Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction
-
Oddo, S., Caccamo, A., Shepherd, J.D., Murphy, M.P., Golde, T.E., Kayed, R., Metherate, R., Mattson, M.P., Akbari, Y. and LaFerla, F.M. (2003) Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron, 39, 409-421.
-
(2003)
Neuron
, vol.39
, pp. 409-421
-
-
Oddo, S.1
Caccamo, A.2
Shepherd, J.D.3
Murphy, M.P.4
Golde, T.E.5
Kayed, R.6
Metherate, R.7
Mattson, M.P.8
Akbari, Y.9
LaFerla, F.M.10
-
57
-
-
77951226607
-
Beta-amyloid1-42 gene transfer model exhibits intraneuronal amyloid, gliosis, tau phosphorylation, and neuronal loss
-
Rebeck, G.W., Hoe, H.S. and Moussa, C.E. (2010) Beta-amyloid1-42 gene transfer model exhibits intraneuronal amyloid, gliosis, tau phosphorylation, and neuronal loss. J. Biol. Chem., 285, 7440-7446.
-
(2010)
J. Biol. Chem
, vol.285
, pp. 7440-7446
-
-
Rebeck, G.W.1
Hoe, H.S.2
Moussa, C.E.3
-
58
-
-
33646377870
-
Interferon signalling network in innate defence
-
Takaoka, A. and Yanai, H. (2006) Interferon signalling network in innate defence. Cell Microbiol., 8, 907-922.
-
(2006)
Cell Microbiol
, vol.8
, pp. 907-922
-
-
Takaoka, A.1
Yanai, H.2
-
59
-
-
80052827401
-
Inflammation in the early stages of neurodegenerative pathology
-
Khandelwal, P.J., Herman, A.M. and Moussa, C.E. (2011) Inflammation in the early stages of neurodegenerative pathology. J. Neuroimmunol., 238, 1-11.
-
(2011)
J. Neuroimmunol
, vol.238
, pp. 1-11
-
-
Khandelwal, P.J.1
Herman, A.M.2
Moussa, C.E.3
-
60
-
-
84871612985
-
Enhanced expression of glia maturation factor correlates with glial activation in the brain of triple transgenic Alzheimer's disease mice
-
Zaheer, S., Thangavel, R., Wu, Y., Khan, M.M., Kempuraj, D. and Zaheer, A. (2013) Enhanced expression of glia maturation factor correlates with glial activation in the brain of triple transgenic Alzheimer's disease mice. Neurochem. Res., 38, 218-225.
-
(2013)
Neurochem. Res
, vol.38
, pp. 218-225
-
-
Zaheer, S.1
Thangavel, R.2
Wu, Y.3
Khan, M.M.4
Kempuraj, D.5
Zaheer, A.6
-
61
-
-
33845680613
-
IFN-beta-induced SOCS-1 negatively regulates CD40 gene expression in macrophages and microglia
-
Qin, H., Wilson, C.A., Lee, S.J. and Benveniste, E.N. (2006) IFN-beta-induced SOCS-1 negatively regulates CD40 gene expression in macrophages and microglia. FASEB J., 20, 985-987.
-
(2006)
FASEB J
, vol.20
, pp. 985-987
-
-
Qin, H.1
Wilson, C.A.2
Lee, S.J.3
Benveniste, E.N.4
-
62
-
-
84879940866
-
Tumor-targeted chlorotoxin-coupled nanoparticles for nucleic acid delivery to glioblastoma cells: A promising system for glioblastoma treatment
-
Costa, P.M., Cardoso, A.L., Mendonca, L.S., Serani, A., Custodia, C., Conceicao, M., Simoes, S., Moreira, J.N., Pereira de Almeida, L. and Pedroso de Lima, M.C. (2013) Tumor-targeted chlorotoxin-coupled nanoparticles for nucleic acid delivery to glioblastoma cells: A promising system for glioblastoma treatment. Mol. Ther. Nucleic Acids, 2, e100.
-
(2013)
Mol. Ther. Nucleic Acids
, vol.2
-
-
Costa, P.M.1
Cardoso, A.L.2
Mendonca, L.S.3
Serani, A.4
Custodia, C.5
Conceicao, M.6
Simoes, S.7
Moreira, J.N.8
Pereira de Almeida, L.9
Pedroso de Lima, M.C.10
-
63
-
-
68649086358
-
Silencing of microRNA-155 in mice during acute inflammatory response leads to derepression of c/ebp Beta and down-regulation of G-CSF
-
Worm, J., Stenvang, J., Petri, A., Frederiksen, K.S., Obad, S., Elmen, J., Hedtjarn, M., Straarup, E.M., Hansen, J.B. and Kauppinen, S. (2009) Silencing of microRNA-155 in mice during acute inflammatory response leads to derepression of c/ebp Beta and down-regulation of G-CSF. Nucleic Acids Res., 37, 5784-5792.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 5784-5792
-
-
Worm, J.1
Stenvang, J.2
Petri, A.3
Frederiksen, K.S.4
Obad, S.5
Elmen, J.6
Hedtjarn, M.7
Straarup, E.M.8
Hansen, J.B.9
Kauppinen, S.10
-
64
-
-
56649123539
-
Epstein-Barr virus latent membrane protein 1 trans-activates miR-155 transcription through the NF-kappaB pathway
-
Gatto, G., Rossi, A., Rossi, D., Kroening, S., Bonatti, S. and Mallardo, M. (2008) Epstein-Barr virus latent membrane protein 1 trans-activates miR-155 transcription through the NF-kappaB pathway. Nucleic Acids Res., 36, 6608-6619.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 6608-6619
-
-
Gatto, G.1
Rossi, A.2
Rossi, D.3
Kroening, S.4
Bonatti, S.5
Mallardo, M.6
-
65
-
-
0033016172
-
Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice
-
Guo, Q., Fu, W., Sopher, B.L., Miller, M.W., Ware, C.B., Martin, G.M. and Mattson, M.P. (1999) Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice. Nat. Med., 5, 101-106.
-
(1999)
Nat. Med
, vol.5
, pp. 101-106
-
-
Guo, Q.1
Fu, W.2
Sopher, B.L.3
Miller, M.W.4
Ware, C.B.5
Martin, G.M.6
Mattson, M.P.7
-
66
-
-
84864658791
-
Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado-Joseph disease
-
Simoes, A.T., Goncalves, N., Koeppen, A., Deglon, N., Kugler, S., Duarte, C.B. and Pereira de Almeida, L. (2012) Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado-Joseph disease. Brain, 135, 2428-2439.
-
(2012)
Brain
, vol.135
, pp. 2428-2439
-
-
Simoes, A.T.1
Goncalves, N.2
Koeppen, A.3
Deglon, N.4
Kugler, S.5
Duarte, C.B.6
Pereira de Almeida, L.7
-
67
-
-
49249118742
-
Neurotoxic effect of oligomeric and fibrillar species of amyloid-beta peptide 1-42: involvement of endoplasmic reticulum calcium release in oligomer-induced cell death
-
Resende, R., Ferreiro, E., Pereira, C. and Resende de Oliveira, C. (2008) Neurotoxic effect of oligomeric and fibrillar species of amyloid-beta peptide 1-42: involvement of endoplasmic reticulum calcium release in oligomer-induced cell death. Neuroscience, 155, 725-737.
-
(2008)
Neuroscience
, vol.155
, pp. 725-737
-
-
Resende, R.1
Ferreiro, E.2
Pereira, C.3
Resende de Oliveira, C.4
-
68
-
-
69049086730
-
Imaging individual microRNAs in single mammalian cells in situ
-
Lu, J. and Tsourkas, A. (2009) Imaging individual microRNAs in single mammalian cells in situ. Nucleic Acids Res., 37, e100.
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Lu, J.1
Tsourkas, A.2
|