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Volumn 2, Issue , 2013, Pages

Tumor-targeted chlorotoxin-coupled nanoparticles for nucleic acid delivery to glioblastoma cells: A promising system for glioblastoma treatment

Author keywords

chlorotoxin; glioblastoma; liposome; miR 21; stable nucleic acid lipid particle

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CHLOROTOXIN; LIPOSOME; NANOCARRIER; PEPTIDE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 84879940866     PISSN: None     EISSN: 21622531     Source Type: Journal    
DOI: 10.1038/mtna.2013.30     Document Type: Article
Times cited : (93)

References (49)
  • 1
    • 34250877865 scopus 로고    scopus 로고
    • Genetic pathways to primary and secondary glioblastoma
    • DOI 10.2353/ajpath.2007.070011
    • Ohgaki, H and Kleihues, P (2007). Genetic pathways to primary and secondary glioblastoma. Am J Pathol 170: 1445-1453. (Pubitemid 47339290)
    • (2007) American Journal of Pathology , vol.170 , Issue.5 , pp. 1445-1453
    • Ohgaki, H.1    Kleihues, P.2
  • 2
    • 76749157903 scopus 로고    scopus 로고
    • Advances in the treatment of malignant gliomas
    • Khasraw, M and Lassman, AB (2010). Advances in the treatment of malignant gliomas. Curr Oncol Rep 12: 26-33.
    • (2010) Curr Oncol Rep , vol.12 , pp. 26-33
    • Khasraw, M.1    Lassman, A.B.2
  • 3
    • 65349121788 scopus 로고    scopus 로고
    • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTCNCIC trial
    • European Organisation for Research and Treatment of Cancer Brain Tumour and Radiation Oncology Groups; National Cancer Institute of Canada Clinical Trials Group.
    • Stupp, R, Hegi, ME, Mason, WP, van den Bent, MJ, Taphoorn, MJ, Janzer, RC et al.; European Organisation for Research and Treatment of Cancer Brain Tumour and Radiation Oncology Groups; National Cancer Institute of Canada Clinical Trials Group. (2009). Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTCNCIC trial. Lancet Oncol 10: 459-466.
    • (2009) Lancet Oncol , vol.10 , pp. 459-466
    • Stupp, R.1    Hegi, M.E.2    Mason, W.P.3    Van Den Bent, M.J.4    Taphoorn, M.J.5    Janzer, R.C.6
  • 6
    • 84873438180 scopus 로고    scopus 로고
    • MicroRNA-21 silencing enhances the cytotoxic effect of the antiangiogenic drug sunitinib in glioblastoma
    • Costa, PM, Cardoso, AL, Nóbrega, C, Pereira de Almeida, LF, Bruce, JN, Canoll, P et al. (2013). MicroRNA-21 silencing enhances the cytotoxic effect of the antiangiogenic drug sunitinib in glioblastoma. Hum Mol Genet 22: 904-918.
    • (2013) Hum Mol Genet , vol.22 , pp. 904-918
    • Costa, P.M.1    Cardoso, A.L.2    Nóbrega, C.3    De Almeida, P.4    Bruce, L.F.5    Canoll P, J.N.6
  • 7
    • 84865041580 scopus 로고    scopus 로고
    • Co-inhibition of microRNA-10b and microRNA-21 exerts synergistic inhibition on the proliferation and invasion of human glioma cells
    • Dong, CG, Wu, WK, Feng, SY, Wang, XJ, Shao, JF and Qiao, J (2012). Co-inhibition of microRNA-10b and microRNA-21 exerts synergistic inhibition on the proliferation and invasion of human glioma cells. Int J Oncol 41: 1005-1012.
    • (2012) Int J Oncol , vol.41 , pp. 1005-1012
    • Dong, C.G.1    Wu, W.K.2    Feng, S.Y.3    Wang, X.J.4    Shao, J.F.5    Qiao, J.6
  • 8
    • 84865988896 scopus 로고    scopus 로고
    • Sequence-dependent synergistic inhibition of human glioma cell lines by combined temozolomide and miR-21 inhibitor gene therapy
    • Qian, X, Ren, Y, Shi, Z, Long, L, Pu, P, Sheng, J et al. (2012). Sequence-dependent synergistic inhibition of human glioma cell lines by combined temozolomide and miR-21 inhibitor gene therapy. Mol Pharm 9: 2636-2645.
    • (2012) Mol Pharm , vol.9 , pp. 2636-2645
    • Qian, X.1    Ren, Y.2    Shi, Z.3    Long, L.4    Pu, P.5    Sheng, J.6
  • 10
    • 56349102126 scopus 로고    scopus 로고
    • Tf-lipoplexes for neuronal siRNA delivery: A promising system to mediate gene silencing in the CNS
    • Cardoso, AL, Simões, S, de Almeida, LP, Plesnila, N, Pedroso de Lima, MC, Wagner, E et al. (2008). Tf-lipoplexes for neuronal siRNA delivery: a promising system to mediate gene silencing in the CNS. J Control Release 132: 113-123.
    • (2008) J Control Release , vol.132 , pp. 113-123
    • Cardoso, A.L.1    Simões, S.2    De Almeida, L.P.3    Plesnila, N.4    De Lima, P.5    Wagner E, M.C.6
  • 12
    • 84855486345 scopus 로고    scopus 로고
    • Oncolytic virus-mediated manipulation of DNA damage responses: Synergy with chemotherapy in killing glioblastoma stem cells
    • Kanai, R, Rabkin, SD, Yip, S, Sgubin, D, Zaupa, CM, Hirose, Y et al. (2012). Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells. J Natl Cancer Inst 104: 42-55.
    • (2012) J Natl Cancer Inst , vol.104 , pp. 42-55
    • Kanai, R.1    Rabkin, S.D.2    Yip, S.3    Sgubin, D.4    Zaupa, C.M.5    Hirose, Y.6
  • 14
    • 65649085603 scopus 로고    scopus 로고
    • Confirming the RNAi-mediated mechanism of action of siRNA-based cancer therapeutics in mice
    • Judge, AD, Robbins, M, Tavakoli, I, Levi, J, Hu, L, Fronda, A et al. (2009). Confirming the RNAi-mediated mechanism of action of siRNA-based cancer therapeutics in mice. J Clin Invest 119: 661-673.
    • (2009) J Clin Invest , vol.119 , pp. 661-673
    • Judge, A.D.1    Robbins, M.2    Tavakoli, I.3    Levi, J.4    Hu, L.5    Fronda, A.6
  • 15
    • 74949127407 scopus 로고    scopus 로고
    • Transferrin receptor-targeted liposomes encapsulating anti-BCR-ABL siRNA or asODN for chronic myeloid leukemia treatment
    • Mendonça, LS, Firmino, F, Moreira, JN, Pedroso de Lima, MC and Simões, S (2010). Transferrin receptor-targeted liposomes encapsulating anti-BCR-ABL siRNA or asODN for chronic myeloid leukemia treatment. Bioconjug Chem 21: 157-168.
    • (2010) Bioconjug Chem , vol.21 , pp. 157-168
    • Mendonça, L.S.1    Firmino, F.2    Moreira, J.N.3    Pedroso De Lima, M.C.4    Simões, S.5
  • 16
    • 33847776789 scopus 로고    scopus 로고
    • Targeted delivery of antitumoral therapy to glioma and other malignancies with synthetic chlorotoxin (TM-601)
    • DOI 10.1517/17425247.4.2.175
    • Mamelak, AN and Jacoby, DB (2007). Targeted delivery of antitumoral therapy to glioma and other malignancies with synthetic chlorotoxin (TM-601). Expert Opin Drug Deliv 4: 175-186. (Pubitemid 46389915)
    • (2007) Expert Opinion on Drug Delivery , vol.4 , Issue.2 , pp. 175-186
    • Mamelak, A.N.1    Jacoby, D.B.2
  • 17
    • 77956011432 scopus 로고    scopus 로고
    • Chlorotoxin bound magnetic nanovector tailored for cancer cell targeting, imaging, and siRNA delivery
    • Veiseh, O, Kievit, FM, Fang, C, Mu, N, Jana, S, Leung, MC et al. (2010). Chlorotoxin bound magnetic nanovector tailored for cancer cell targeting, imaging, and siRNA delivery. Biomaterials 31: 8032-8042.
    • (2010) Biomaterials , vol.31 , pp. 8032-8042
    • Veiseh, O.1    Kievit, F.M.2    Fang, C.3    Mu, N.4    Jana, S.5    Leung, M.C.6
  • 18
    • 68049144958 scopus 로고    scopus 로고
    • Specific targeting of brain tumors with an optical/magnetic resonance imaging nanoprobe across the bloodbrain barrier
    • Veiseh, O, Sun, C, Fang, C, Bhattarai, N, Gunn, J, Kievit, F et al. (2009). Specific targeting of brain tumors with an optical/magnetic resonance imaging nanoprobe across the bloodbrain barrier. Cancer Res 69: 6200-6207.
    • (2009) Cancer Res , vol.69 , pp. 6200-6207
    • Veiseh, O.1    Sun, C.2    Fang, C.3    Bhattarai, N.4    Gunn, J.5    Kievit, F.6
  • 19
    • 0037423212 scopus 로고    scopus 로고
    • Chlorotoxin inhibits glioma cell invasion via matrix metalloproteinase-2
    • DOI 10.1074/jbc.M205662200
    • Deshane, J, Garner, CC and Sontheimer, H (2003). Chlorotoxin inhibits glioma cell invasion via matrix metalloproteinase-2. J Biol Chem 278: 4135-4144. (Pubitemid 36801150)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.6 , pp. 4135-4144
    • Deshane, J.1    Garner, C.C.2    Sontheimer, H.3
  • 20
    • 47549109566 scopus 로고    scopus 로고
    • MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene
    • DOI 10.1038/onc.2008.72, PII ONC200872
    • Lu, Z, Liu, M, Stribinskis, V, Klinge, CM, Ramos, KS, Colburn, NH et al. (2008). MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene. Oncogene 27: 4373-4379. (Pubitemid 352010003)
    • (2008) Oncogene , vol.27 , Issue.31 , pp. 4373-4379
    • Lu, Z.1    Liu, M.2    Stribinskis, V.3    Klinge, C.M.4    Ramos, K.S.5    Colburn, N.H.6    Li, Y.7
  • 21
    • 34547524771 scopus 로고    scopus 로고
    • MicroRNA-21 Regulates Expression of the PTEN Tumor Suppressor Gene in Human Hepatocellular Cancer
    • DOI 10.1053/j.gastro.2007.05.022, PII S0016508507010025
    • Meng, F, Henson, R, Wehbe-Janek, H, Ghoshal, K, Jacob, ST and Patel, T (2007). MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 133: 647-658. (Pubitemid 47187346)
    • (2007) Gastroenterology , vol.133 , Issue.2 , pp. 647-658
    • Meng, F.1    Henson, R.2    Wehbe-Janek, H.3    Ghoshal, K.4    Jacob, S.T.5    Patel, T.6
  • 23
    • 0035946624 scopus 로고    scopus 로고
    • Cationic lipid-DNA complexes in gene delivery: From biophysics to biological applications
    • DOI 10.1016/S0169-409X(01)00110-7, PII S0169409X01001107
    • Pedroso de Lima, MC, Simoes, S, Pires, P, Faneca, H and Duzgunes, N (2001). Cationic lipid-DNA complexes in gene delivery: from biophysics to biological applications. Adv Drug Deliv Rev 47: 277-294. (Pubitemid 32324118)
    • (2001) Advanced Drug Delivery Reviews , vol.47 , Issue.2-3 , pp. 277-294
    • Pedroso De Lima, M.C.1    Simoes, S.2    Pires, P.3    Faneca, H.4    Duzgunes, N.5
  • 27
    • 51049104302 scopus 로고    scopus 로고
    • Pharmacokinetics and biodistribution of nanoparticles
    • Li, SD and Huang, L (2008). Pharmacokinetics and biodistribution of nanoparticles. Mol Pharm 5: 496-504.
    • (2008) Mol Pharm , vol.5 , pp. 496-504
    • Li, S.D.1    Huang, L.2
  • 28
    • 33846493607 scopus 로고    scopus 로고
    • Pegylation of liposomes favours the endosomal degradation of the delivered phosphodiester oligonucleotides
    • DOI 10.1016/j.jconrel.2006.10.029, PII S016836590600589X
    • Remaut, K, Lucas, B, Braeckmans, K, Demeester, J and De Smedt, SC (2007). Pegylation of liposomes favours the endosomal degradation of the delivered phosphodiester oligonucleotides. J Control Release 117: 256-266. (Pubitemid 46161877)
    • (2007) Journal of Controlled Release , vol.117 , Issue.2 , pp. 256-266
    • Remaut, K.1    Lucas, B.2    Braeckmans, K.3    Demeester, J.4    De Smedt, S.C.5
  • 30
    • 41749113108 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
    • DOI 10.1038/sj.onc.1210856, PII 1210856
    • Asangani, IA, Rasheed, SA, Nikolova, DA, Leupold, JH, Colburn, NH, Post, S et al. (2008). MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 27: 2128-2136. (Pubitemid 351485639)
    • (2008) Oncogene , vol.27 , Issue.15 , pp. 2128-2136
    • Asangani, I.A.1    Rasheed, S.A.K.2    Nikolova, D.A.3    Leupold, J.H.4    Colburn, N.H.5    Post, S.6    Allgayer, H.7
  • 31
    • 79959977098 scopus 로고    scopus 로고
    • Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo
    • Gaur, AB, Holbeck, SL, Colburn, NH and Israel, MA (2011). Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo. Neuro-oncology 13: 580-590.
    • (2011) Neuro-oncology , vol.13 , pp. 580-590
    • Gaur, A.B.1    Holbeck, S.L.2    Colburn, N.H.3    Israel, M.A.4
  • 33
    • 79959794242 scopus 로고    scopus 로고
    • PI3Kinase signaling in glioblastoma
    • Lino, MM and Merlo, A (2011). PI3Kinase signaling in glioblastoma. J Neurooncol 103: 417-427.
    • (2011) J Neurooncol , vol.103 , pp. 417-427
    • Lino, M.M.1    Merlo, A.2
  • 34
    • 0035825611 scopus 로고    scopus 로고
    • A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-κB or ODC transactivation
    • DOI 10.1038/sj.onc.1204137
    • Yang, HS, Jansen, AP, Nair, R, Shibahara, K, Verma, AK, Cmarik, JL et al. (2001). A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-kappaB or ODC transactivation. Oncogene 20: 669-676. (Pubitemid 32179335)
    • (2001) Oncogene , vol.20 , Issue.6 , pp. 669-676
    • Yang, H.-S.1    Jansen, A.P.2    Nair, R.3    Shibahara, K.4    Verma, A.K.5    Cmarik, J.L.6    Colburn, N.H.7
  • 35
    • 77749279909 scopus 로고    scopus 로고
    • Co-delivery of as-miR-21 and 5-FU by poly(amidoamine) dendrimer attenuates human glioma cell growth in vitro
    • Ren, Y, Kang, CS, Yuan, XB, Zhou, X, Xu, P, Han, L et al. (2010). Co-delivery of as-miR-21 and 5-FU by poly(amidoamine) dendrimer attenuates human glioma cell growth in vitro. J Biomater Sci Polym Ed 21: 303-314.
    • (2010) J Biomater Sci Polym Ed , vol.21 , pp. 303-314
    • Ren, Y.1    Kang, C.S.2    Yuan, X.B.3    Zhou, X.4    Xu, P.5    Han, L.6
  • 36
    • 77349125856 scopus 로고    scopus 로고
    • MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol
    • Ren, Y, Zhou, X, Mei, M, Yuan, XB, Han, L, Wang, GX et al. (2010). MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol. BMC Cancer 10: 27.
    • (2010) BMC Cancer , vol.10 , pp. 27
    • Ren, Y.1    Zhou, X.2    Mei, M.3    Yuan, X.B.4    Han, L.5    Wang, G.X.6
  • 37
    • 79959795987 scopus 로고    scopus 로고
    • Phase II study of sunitinib malate in patients with recurrent high-grade glioma
    • Neyns, B, Sadones, J, Chaskis, C, Dujardin, M, Everaert, H, Lv, S et al. (2011). Phase II study of sunitinib malate in patients with recurrent high-grade glioma. J Neurooncol 103: 491-501.
    • (2011) J Neurooncol , vol.103 , pp. 491-501
    • Neyns, B.1    Sadones, J.2    Chaskis, C.3    Dujardin, M.4    Everaert, H.5    Lv, S.6
  • 38
    • 0035575846 scopus 로고    scopus 로고
    • Targeting Stealth liposomes in a murine model of human small cell lung cancer
    • DOI 10.1016/S0005-2736(01)00411-4, PII S0005273601004114
    • Moreira, JN, Gaspar, R and Allen, TM (2001). Targeting Stealth liposomes in a murine model of human small cell lung cancer. Biochim Biophys Acta 1515: 167-176. (Pubitemid 33086833)
    • (2001) Biochimica et Biophysica Acta - Biomembranes , vol.1515 , Issue.2 , pp. 167-176
    • Moreira, J.N.1    Gaspar, R.2    Allen, T.M.3
  • 41
    • 33846821991 scopus 로고    scopus 로고
    • Effect of cationic carriers on the pharmacokinetics and tumor localization of nucleic acids after intravenous administration
    • DOI 10.1016/j.ijpharm.2006.10.029, PII S0378517306009021
    • de Wolf, HK, Snel, CJ, Verbaan, FJ, Schiffelers, RM, Hennink, WE and Storm, G (2007). Effect of cationic carriers on the pharmacokinetics and tumor localization of nucleic acids after intravenous administration. Int J Pharm 331: 167-175. (Pubitemid 46216670)
    • (2007) International Journal of Pharmaceutics , vol.331 , Issue.2 , pp. 167-175
    • De Wolf, H.K.1    Snel, C.J.2    Verbaan, F.J.3    Schiffelers, R.M.4    Hennink, W.E.5    Storm, G.6
  • 42
    • 79961082146 scopus 로고    scopus 로고
    • Survivin silencing as a promising strategy to enhance the sensitivity of cancer cells to chemotherapeutic agents
    • Trabulo, S, Cardoso, AM, Santos-Ferreira, T, Cardoso, AL, Simões, S and Pedroso de Lima, MC (2011). Survivin silencing as a promising strategy to enhance the sensitivity of cancer cells to chemotherapeutic agents. Mol Pharm 8: 1120-1131.
    • (2011) Mol Pharm , vol.8 , pp. 1120-1131
    • Trabulo, S.1    Cardoso, A.M.2    Santos-Ferreira, T.3    Cardoso, A.L.4    Simões, S.5    Pedroso De Lima, M.C.6
  • 43
    • 0035983279 scopus 로고    scopus 로고
    • Chlorotoxin, a scorpion-derived peptide, specifically binds to gliomas and tumors of neuroectodermal origin
    • DOI 10.1002/glia.10083
    • Lyons, SA, O'Neal, J and Sontheimer, H (2002). Chlorotoxin, a scorpion-derived peptide, specifically binds to gliomas and tumors of neuroectodermal origin. Glia 39: 162-173. (Pubitemid 34817056)
    • (2002) GLIA , vol.39 , Issue.2 , pp. 162-173
    • Lyons, S.A.1    O'Neal, J.2    Sontheimer, H.3
  • 45
    • 33947666141 scopus 로고    scopus 로고
    • The Liebermann-Burchard reaction: Sulfonation, desaturation, and rearrangment of cholesterol in acid
    • DOI 10.1007/s11745-006-3013-5
    • Xiong, Q, Wilson, WK and Pang, J (2007). The Liebermann-Burchard reaction: sulfonation, desaturation, and rearrangment of cholesterol in acid. Lipids 42: 87-96. (Pubitemid 46490747)
    • (2007) Lipids , vol.42 , Issue.1 , pp. 87-96
    • Xiong, Q.1    Wilson, W.K.2    Pang, J.3
  • 46
    • 0036200912 scopus 로고    scopus 로고
    • Use of the post-insertion technique to insert peptide ligands into pre-formed stealth liposomes with retention of binding activity and cytotoxicity
    • DOI 10.1023/A:1014434732752
    • Moreira, JN, Ishida, T, Gaspar, R and Allen, TM (2002). Use of the post-insertion technique to insert peptide ligands into pre-formed stealth liposomes with retention of binding activity and cytotoxicity. Pharm Res 19: 265-269. (Pubitemid 34211842)
    • (2002) Pharmaceutical Research , vol.19 , Issue.3 , pp. 265-269
    • Moreira, J.N.1    Ishida, T.2    Gaspar, R.3    Allen, T.M.4
  • 47
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RTPCR
    • Pfaffl, MW (2001). A new mathematical model for relative quantification in real-time RTPCR. Nucleic Acids Res 29: e45.
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1
  • 48
    • 84863205849 scopus 로고    scopus 로고
    • NIH Image to ImageJ: 25 years of image analysis
    • Schneider, CA, Rasband, WS and Eliceiri, KW (2012). NIH Image to ImageJ: 25 years of image analysis. Nat Methods 9: 671-675.
    • (2012) Nat Methods , vol.9 , pp. 671-675
    • Schneider, C.A.1    Rasband, W.S.2    Eliceiri, K.W.3


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