A Smoothened receptor agonist is neuroprotective and promotes regeneration after ischemic brain injury

Cell Death and Disease

Volumn 5, Issue 10, 2014, Pages

  Chechneva, O V ^a   Mayrhofer, F ^b   Daugherty, D J ^a   Krishnamurty, R G ^a   Bannerman, P ^b   Pleasure, D E ^a,b   Deng, W ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SHRINERS HOSPITALS FOR CHILDREN NORTHERN CALIFORNIA   (United States)

^c HUBEI UNIVERSITY OF ARTS AND SCIENCE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROPROTECTIVE AGENT; PURMORPHAMINE; SONIC HEDGEHOG PROTEIN; TISSUE PLASMINOGEN ACTIVATOR; TRANSCRIPTION FACTOR GLI1; UNCLASSIFIED DRUG; G PROTEIN COUPLED RECEPTOR; MORPHOLINE DERIVATIVE; PURINE DERIVATIVE; SMO PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTOSIS; ATTENUATION; BLOOD BRAIN BARRIER; BRAIN INFARCTION; BRAIN ISCHEMIA; CARCINOGENICITY; CELL DEATH; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NERVE CELL LESION; NERVOUS SYSTEM INFLAMMATION; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; REGENERATION; SIGNAL TRANSDUCTION; AGONISTS; ANIMAL; BRAIN CORTEX; C57BL MOUSE; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; INFLAMMATION; METABOLISM; NERVE CELL; NERVE REGENERATION; PATHOLOGY; PATHOPHYSIOLOGY; TIME; UPREGULATION;

ANIMALIA; ERINACEIDAE;

ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; HEDGEHOG PROTEINS; INFLAMMATION; MALE; MICE, INBRED C57BL; MORPHOLINES; NERVE REGENERATION; NEURONS; NEUROPROTECTIVE AGENTS; PURINES; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; STROKE; TIME FACTORS; TISSUE PLASMINOGEN ACTIVATOR; UP-REGULATION;

EID: 84926225770     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.446     Document Type: Article

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