Tissue-type plasminogen activator has a neuroprotective effect in the ischemic brain mediated by neuronal TNF-α

Journal of Cerebral Blood Flow and Metabolism

Volumn 32, Issue 1, 2012, Pages 57-69

  Haile, Woldeab B ^a   Wu, Jialing ^a,b   Echeverry, Ramiro ^a   Wu, Fang ^a   An, Jie ^c   Yepes, Manuel ^a,d  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Tianjin Huanhu Hospital   (China)

^c SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d ATLANTA VA MEDICAL CENTER   (United States)

Author keywords

cerebral ischemia; tissue type plasminogen activator; tumor necrosis factor

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1A; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PLASMIN; TISSUE PLASMINOGEN ACTIVATOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN HYPOXIA; BRAIN ISCHEMIA; CELL SURVIVAL; CONCENTRATION (PARAMETERS); GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; ISCHEMIC PRECONDITIONING; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVE CELL; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; ENZYME-LINKED IMMUNOSORBENT ASSAY; HYPOXIA-ISCHEMIA, BRAIN; ISCHEMIC PRECONDITIONING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; NEUROPROTECTIVE AGENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TISSUE PLASMINOGEN ACTIVATOR; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84855347516     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2011.106     Document Type: Article

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