Anti-oxidative, anti-apoptotic, and pro-angiogenic effects mediate functional improvement by sonic hedgehog against focal cerebral ischemia in rats

Experimental Neurology

Volumn 247, Issue , 2013, Pages 680-688

  Huang, Shiang Suo ^a,b   Cheng, Henrich ^c   Tang, Ching Min ^d   Nien, Mao Wei ^a,b   Huang, Yuahn Sieh ^e   Lee, I Huei ^d   Yin, Jiu Haw ^f   Kuo, Terry B J ^d   Yang, Cheryl C H ^d   Tsai, Shen Kou ^f   Yang, Ding I ^d  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

^e NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^f CHENG HSIN GENERAL HOSPITAL   (Taiwan)

Author keywords

Angiogenesis; Anti apoptosis; Anti oxidation; Focal ischemia; Middle cerebral artery occlusion

Indexed keywords

BROXURIDINE; CYCLOPAMINE; NESTIN; SONIC HEDGEHOG PROTEIN;

AMINO TERMINAL SEQUENCE; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; ASTROCYTOSIS; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CELL PROLIFERATION; CONTROLLED STUDY; DRUG MECHANISM; IMMUNOHISTOCHEMISTRY; LIPID PEROXIDATION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEURAL STEM CELL; NEUROPROTECTION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN METABOLISM; RAT; REPERFUSION INJURY;

ANGIOGENESIS; ANTI-APOPTOSIS; ANTI-OXIDATION; FOCAL ISCHEMIA; MIDDLE CEREBRAL ARTERY OCCLUSION;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BROMODEOXYURIDINE; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HAND STRENGTH; HEDGEHOG PROTEINS; IN SITU NICK-END LABELING; INFARCTION, MIDDLE CEREBRAL ARTERY; LIPID PEROXIDATION; MALE; MOTOR ACTIVITY; NEOVASCULARIZATION, PATHOLOGIC; NESTIN; NEURAL STEM CELLS; NEUROLOGIC EXAMINATION; OXIDATION-REDUCTION; RATS; RATS, LONG-EVANS; ROTAROD PERFORMANCE TEST; VERATRUM ALKALOIDS;

EID: 84881370807     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2013.03.004     Document Type: Article

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