Chelation of dietary iron prevents iron accumulation and macrophage infiltration in the type i diabetic kidney

European Journal of Pharmacology

Volumn 756, Issue , 2015, Pages 85-91

  Morita, Tatsuyori ^a,b   Nakano, Daisuke ^a   Kitada, Kento ^a   Morimoto, Satoshi ^c   Ichihara, Atsuhiro ^c   Hitomi, Hirofumi ^a   Kobori, Hiroyuki ^a   Shiojima, Ichiro ^c   Nishiyama, Akira ^a  

^a KAGAWA UNIVERSITY   (Japan)

^b KANSAI MEDICAL UNIVERSITY   (Japan)

^c TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Cellular senescence; Diabetic nephropathy; Iron; P21; Proximal tubular cells

Indexed keywords

DEFERASIROX; PROTEIN P16; PROTEIN P21; BENZOIC ACID DERIVATIVE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; IRON; IRON CHELATING AGENT; IRON INTAKE; TRIAZOLE DERIVATIVE;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY DETECTION; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DRUG EFFICACY; DRUG SAFETY; GLUCOSE BLOOD LEVEL; HEMATOCRIT; HEMOGLOBIN BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; INSULIN DEPENDENT DIABETES MELLITUS; IRON CHELATION; IRON INTAKE; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENESCENCE; ANIMAL; C57BL MOUSE; CELL AGING; COMPLICATION; DEFICIENCY; DIABETIC NEPHROPATHIES; DRUG EFFECTS; GENE INACTIVATION; GENETICS; IMMUNOLOGY; KIDNEY; METABOLISM; PATHOLOGY;

ANIMALS; BENZOATES; CELL AGING; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DIABETES MELLITUS, TYPE 1; DIABETIC NEPHROPATHIES; GENE KNOCKOUT TECHNIQUES; IRON; IRON CHELATING AGENTS; IRON, DIETARY; KIDNEY; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; TRIAZOLES;

EID: 84926218025     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2015.03.053     Document Type: Article

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