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Volumn 31, Issue 3, 2011, Pages 683-690

Serum hepcidin and macrophage iron correlate with MCP-1 release and vascular damage in patients with metabolic syndrome alterations

Author keywords

atherosclerosis; cytokines; free radicals free radical scavengers; iron; macrophages; risk factors

Indexed keywords

CD36 ANTIGEN; FERRIC AMMONIUM CITRATE; HEMOJUVELIN; HEPCIDIN; HEPCIDIN 25; INTERLEUKIN 6; IRON; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 79952191602     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.110.214858     Document Type: Article
Times cited : (81)

References (49)
  • 1
    • 33846549431 scopus 로고    scopus 로고
    • Association of body iron stores with low molecular weight iron and oxidant damage of human atherosclerotic plaques
    • DOI 10.1016/j.freeradbiomed.2006.11.014, PII S0891584906007520
    • Lapenna D, Pierdomenico SD, Ciofani G, Ucchino S, Neri M, Giamberardino MA, Cuccurullo F. Association of body iron stores with low molecular weight iron and oxidant damage of human atherosclerotic plaques. Free Radic Biol Med. 2007;42:492-498. (Pubitemid 46162117)
    • (2007) Free Radical Biology and Medicine , vol.42 , Issue.4 , pp. 492-498
    • Lapenna, D.1    Pierdomenico, S.D.2    Ciofani, G.3    Ucchino, S.4    Neri, M.5    Giamberardino, M.A.6    Cuccurullo, F.7
  • 3
    • 34548429748 scopus 로고    scopus 로고
    • Macrophage iron, hepcidin, and atherosclerotic plaque stability
    • DOI 10.3181/0703-MR-54
    • Sullivan JL. Macrophage iron, hepcidin, and atherosclerotic plaque stability. Exp Biol Med (Maywood). 2007;232:1014-1020. (Pubitemid 47358184)
    • (2007) Experimental Biology and Medicine , vol.232 , Issue.8 , pp. 1014-1020
    • Sullivan, J.L.1
  • 4
    • 40449120460 scopus 로고    scopus 로고
    • Iron depletion by deferoxamine up-regulates glucose uptake and insulin signaling in hepatoma cells and in rat liver
    • DOI 10.2353/ajpath.2008.070097
    • Dongiovanni P, Valenti L, Ludovica Fracanzani A, Gatti S, Cairo G, Fargion S. Iron depletion by deferoxamine up-regulates glucose uptake and insulin signaling in hepatoma cells and in rat liver. Am J Pathol. 2008;172:738-747. (Pubitemid 351354546)
    • (2008) American Journal of Pathology , vol.172 , Issue.3 , pp. 738-747
    • Dongiovanni, P.1    Valenti, L.2    Fracanzani, A.L.3    Gatti, S.4    Cairo, G.5    Fargion, S.6
  • 7
    • 15744362815 scopus 로고    scopus 로고
    • Iron loading increases cholesterol accumulation and macrophage scavenger receptor I expression in THP-1 mononuclear phagocytes
    • DOI 10.1016/j.metabol.2004.10.012
    • Kraml PJ, Klein RL, Huang Y, Nareika A, Lopes-Virella MF. Iron loading increases cholesterol accumulation and macrophage scavenger receptor I expression in THP-1 mononuclear phagocytes. Metabolism. 2005;54:453-459. (Pubitemid 40410444)
    • (2005) Metabolism: Clinical and Experimental , vol.54 , Issue.4 , pp. 453-459
    • Kraml, P.J.1    Klein, R.L.2    Huang, Y.3    Nareika, A.4    Lopes-Virella, M.F.5
  • 8
    • 0038350932 scopus 로고    scopus 로고
    • Chronic iron administration increases vascular oxidative stress and accelerates arterial thrombosis
    • Day SM, Duquaine D, Mundada LV, Menon RG, Khan BV, Rajagopalan S, Fay WP. Chronic iron administration increases vascular oxidative stress and accelerates arterial thrombosis. Circulation. 2003;107: 2601-2606. (Pubitemid 36628943)
    • (2003) Circulation , vol.107 , Issue.20 , pp. 2601-2606
    • Day, S.M.1    Duquaine, D.2    Mundada, L.V.3    Menon, R.G.4    Khan, B.V.5    Rajagopalan, S.6    Fay, W.P.7
  • 9
    • 0033537671 scopus 로고    scopus 로고
    • Iron-deficient diet reduces atherosclerotic lesions in apoE-deficient mice
    • Lee TS, Shiao MS, Pan CC, Chau LY. Iron-deficient diet reduces atherosclerotic lesions in apoE-deficient mice. Circulation. 1999;99: 1222-1229.
    • (1999) Circulation , vol.99 , pp. 1222-1229
    • Lee, T.S.1    Shiao, M.S.2    Pan, C.C.3    Chau, L.Y.4
  • 10
    • 0032167670 scopus 로고    scopus 로고
    • Donation of blood is associated with reduced risk of myocardial infarction: The Kuopio Ischaemic Heart Disease Risk Factor Study
    • Salonen JT, Tuomainen TP, Salonen R, Lakka TA, Nyyssonen K. Donation of blood is associated with reduced risk of myocardial infarction. The Kuopio Ischaemic Heart Disease Risk Factor Study. Am J Epidemiol. 1998;148:445-451. (Pubitemid 28411101)
    • (1998) American Journal of Epidemiology , vol.148 , Issue.5 , pp. 445-451
    • Salonen, J.T.1    Tuomainen, T.-P.2    Salonen, R.3    Lakka, T.A.4    Nyyssonen, K.5
  • 13
    • 0028212084 scopus 로고
    • Iron status and coronary heart disease: Negative findings from the NHANES I Epidemiologic Follow-up Study
    • Liao Y, Cooper RS, McGee DL. Iron status and coronary heart disease: negative findings from the NHANES I epidemiologic follow-up study. Am J Epidemiol. 1994;139:704-712. (Pubitemid 24121279)
    • (1994) American Journal of Epidemiology , vol.139 , Issue.7 , pp. 704-712
    • Liao, Y.1    Cooper, R.S.2    McGee, D.L.3
  • 14
    • 36349028180 scopus 로고    scopus 로고
    • Hemochromatosis: An endocrine liver disease
    • DOI 10.1002/hep.21886
    • Pietrangelo A. Hemochromatosis: an endocrine liver disease. Hepatology. 2007;46:1291-1301. (Pubitemid 350144793)
    • (2007) Hepatology , vol.46 , Issue.4 , pp. 1291-1301
    • Pietrangelo, A.1
  • 15
    • 10844258104 scopus 로고    scopus 로고
    • Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
    • DOI 10.1126/science.1104742
    • Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, Ganz T, Kaplan J. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science. 2004;306: 2090-2093. (Pubitemid 40007660)
    • (2004) Science , vol.306 , Issue.5704 , pp. 2090-2093
    • Nemeth, E.1    Tuttle, M.S.2    Powelson, J.3    Vaughn, M.D.4    Donovan, A.5    Ward, D.M.6    Ganz, T.7    Kaplan, J.8
  • 19
    • 0015108443 scopus 로고
    • Protective effects of hemochromatosis against senile and diabetic angiopathies
    • Pirart J, Barbier P. Protective effects of hemochromatosis against senile and diabetic angiopathies. Diabetologia. 1971;7:227-236.
    • (1971) Diabetologia , vol.7 , pp. 227-236
    • Pirart, J.1    Barbier, P.2
  • 23
    • 8644245902 scopus 로고    scopus 로고
    • Secretion of ferritin by iron-laden macrophages and influence of lipoproteins
    • DOI 10.1080/10715760400011692
    • Yuan XM, Li W, Baird SK, Carlsson M, Melefors O. Secretion of ferritin by iron-laden macrophages and influence of lipoproteins. Free Radic Res. 2004;38:1133-1142. (Pubitemid 39504349)
    • (2004) Free Radical Research , vol.38 , Issue.10 , pp. 1133-1142
    • Yuan, X.-M.1    Li, W.2    Baird, S.K.3    Carlsson, M.4    Melefors, O.5
  • 25
    • 77952557403 scopus 로고    scopus 로고
    • The iron chelator, desferrioxamine, reduces inflammation and atherosclerotic lesion development in experimental mice
    • Zhang WJ, Wei H, Frei B. The iron chelator, desferrioxamine, reduces inflammation and atherosclerotic lesion development in experimental mice. Exp Biol Med (Maywood). 2010;235:633-641.
    • (2010) Exp Biol Med (Maywood) , vol.235 , pp. 633-641
    • Zhang, W.J.1    Wei, H.2    Frei, B.3
  • 26
    • 34249098685 scopus 로고    scopus 로고
    • Iron depletion by phlebotomy improves insulin resistance in patients with nonalcoholic fatty liver disease and hyperferritinemia: Evidence from a case-control study
    • DOI 10.1111/j.1572-0241.2007.01192.x
    • Valenti L, Fracanzani AL, Dongiovanni P, Bugianesi E, Marchesini G, Manzini P, Vanni E, Fargion S. Iron depletion by phlebotomy improves insulin resistance in patients with nonalcoholic fatty liver disease and hyperferritinemia: evidence from a case-control study. Am J Gastroenterol. 2007;102:1251-1258. (Pubitemid 46802029)
    • (2007) American Journal of Gastroenterology , vol.102 , Issue.6 , pp. 1251-1258
    • Valenti, L.1    Fracanzani, A.L.2    Dongiovanni, P.3    Bugianesi, E.4    Marchesini, G.5    Manzini, P.6    Vanni, E.7    Fargion, S.8
  • 28
    • 43949134238 scopus 로고    scopus 로고
    • HFE mutations in nonalcoholic fatty liver disease
    • DOI 10.1002/hep.22059
    • Valenti L, Dongiovanni P, Fracanzani AL, Fargion S. HFE mutations in nonalcoholic fatty liver disease. Hepatology. 2008;47:1794-1795. (Pubitemid 351702767)
    • (2008) Hepatology , vol.47 , Issue.5 , pp. 1794-1795
    • Valenti, L.1    Dongiovanni, P.2    Fracanzani, A.L.3    Fargion, S.4
  • 31
    • 0030894809 scopus 로고    scopus 로고
    • Inappropriately high iron regulatory protein activity in monocytes of patients with genetic hemochromatosis
    • Cairo G, Recalcati S, Montosi G, Castrusini E, Conte D, Pietrangelo A. Inappropriately high iron regulatory protein activity in monocytes of patients with genetic hemochromatosis. Blood. 1997;89:2546-2553. (Pubitemid 27143304)
    • (1997) Blood , vol.89 , Issue.7 , pp. 2546-2553
    • Cairo, G.1    Recalcati, S.2    Montosi, G.3    Castrusini, E.4    Conte, D.5    Pietrangelo, A.6
  • 35
    • 33645421347 scopus 로고    scopus 로고
    • Iron regulatory proteins 1 and 2 in human monocytes, macrophages and duodenum: Expression and regulation in hereditary hemochromatosis and iron deficiency
    • Recalcati S, Alberghini A, Campanella A, Gianelli U, De Camilli E, Conte D, Cairo G. Iron regulatory proteins 1 and 2 in human monocytes, macrophages and duodenum: expression and regulation in hereditary hemochromatosis and iron deficiency. Haematologica. 2006;91:303-310.
    • (2006) Haematologica , vol.91 , pp. 303-310
    • Recalcati, S.1    Alberghini, A.2    Campanella, A.3    Gianelli, U.4    De Camilli, E.5    Conte, D.6    Cairo, G.7
  • 36
    • 24144476577 scopus 로고    scopus 로고
    • Heme oxygenase and atherosclerosis
    • DOI 10.1161/01.ATV.0000178169.95781.49
    • Morita T. Heme oxygenase and atherosclerosis. Arterioscler Thromb Vasc Biol. 2005;25:1786-1795. (Pubitemid 41243444)
    • (2005) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.25 , Issue.9 , pp. 1786-1795
    • Morita, T.1
  • 39
    • 53149123286 scopus 로고    scopus 로고
    • Attenuated inflammatory responses in hemochromatosis reveal a role for iron in the regulation of macrophage cytokine translation
    • Wang L, Johnson EE, Shi HN, Walker WA, Wessling-Resnick M, Cherayil BJ. Attenuated inflammatory responses in hemochromatosis reveal a role for iron in the regulation of macrophage cytokine translation. J Immunol. 2008;181:2723-2731.
    • (2008) J Immunol , vol.181 , pp. 2723-2731
    • Wang, L.1    Johnson, E.E.2    Shi, H.N.3    Walker, W.A.4    Wessling-Resnick, M.5    Cherayil, B.J.6
  • 40
    • 0019434645 scopus 로고
    • Iron and the sex difference in heart disease risk
    • Sullivan JL. Iron and the sex difference in heart disease risk. Lancet. 1981;1:1293-1294. (Pubitemid 11111356)
    • (1981) Lancet , vol.1 , Issue.8233 , pp. 1293-1294
    • Sullivan, J.L.1
  • 43
    • 68049088677 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 in acute coronary syndromes: Complex vicious interaction
    • Amasyali B, Kose S, Kursaklioglu H, Barcin C, Kilic A. Monocyte chemoattractant protein-1 in acute coronary syndromes: complex vicious interaction. Int J Cardiol. 2009;136:356-357.
    • (2009) Int J Cardiol , vol.136 , pp. 356-357
    • Amasyali, B.1    Kose, S.2    Kursaklioglu, H.3    Barcin, C.4    Kilic, A.5
  • 44
    • 0026075699 scopus 로고
    • Monocyte chemoattractant protein-1 in human atheromatous plaques
    • Nelken NA, Coughlin SR, Gordon D, Wilcox JN. Monocyte chemoattractant protein-1 in human atheromatous plaques. J Clin Invest. 1991; 88:1121-1127.
    • (1991) J Clin Invest , vol.88 , pp. 1121-1127
    • Nelken, N.A.1    Coughlin, S.R.2    Gordon, D.3    Wilcox, J.N.4
  • 45
    • 0032134003 scopus 로고    scopus 로고
    • Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice
    • Gu L, Okada Y, Clinton SK, Gerard C, Sukhova GK, Libby P, Rollins BJ. Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice. Mol Cell. 1998;2: 275-281. (Pubitemid 128373654)
    • (1998) Molecular Cell , vol.2 , Issue.2 , pp. 275-281
    • Gu, L.1    Okada, Y.2    Clinton, S.K.3    Gerard, C.4    Sukhova, G.K.5    Libby, P.6    Rollins, B.J.7
  • 46
    • 31744452154 scopus 로고    scopus 로고
    • Parenteral iron treatment induces MCP-1 accumulation in plasma, normal kidneys, and in experimental nephropathy
    • DOI 10.1111/j.1523-1755.2005.00565.x, PII 4494756
    • Zager RA. Parenteral iron treatment induces MCP-1 accumulation in plasma, normal kidneys, and in experimental nephropathy. Kidney Int. 2005;68:1533-1542. (Pubitemid 43173381)
    • (2005) Kidney International , vol.68 , Issue.4 , pp. 1533-1542
    • Zager, R.A.1
  • 47
    • 33645508160 scopus 로고    scopus 로고
    • Proinflammatory effects of iron sucrose in chronic kidney disease
    • Agarwal R. Proinflammatory effects of iron sucrose in chronic kidney disease. Kidney Int. 2006;69:1259-1263.
    • (2006) Kidney Int , vol.69 , pp. 1259-1263
    • Agarwal, R.1
  • 49
    • 34548348137 scopus 로고    scopus 로고
    • Elevated MCP-1 serum levels are associated with the H63D mutation and not the C282Y mutation in hereditary hemochromatosis
    • DOI 10.1111/j.1399-0039.2007.00895.x
    • Lawless MW, White M, Mankan AK, O'Dwyer MJ, Norris S. Elevated MCP-1 serum levels are associated with the H63D mutation and not the C282Y mutation in hereditary hemochromatosis. Tissue Antigens. 2007; 70:294-300. (Pubitemid 47340724)
    • (2007) Tissue Antigens , vol.70 , Issue.4 , pp. 294-300
    • Lawless, M.W.1    White, M.2    Mankan, A.K.3    O'Dwyer, M.J.4    Norris, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.