Hypoxia-inducible TAp73 supports tumorigenesis by regulating the angiogenic transcriptome

Nature Cell Biology

Volumn 17, Issue 4, 2015, Pages 511-523

  Dulloo, Iqbal ^a   Phang, Beng Hooi ^a   Othman, Rashidah ^a   Tan, Soo Yong ^b   Vijayaraghavan, Aadhitthya ^c   Goh, Liang Kee ^c   Martin Lopez, Marta ^d   Marques, Margarita M ^d   Li, Chun Wei ^e   Wang, De Yun ^e   Marín, Maria Carmen ^d   Xian, Wa ^f   Mckeon, Frank ^g   Sabapathy, Kanaga ^a,c,e  

^a DIVISION OF MEDICAL ONCOLOGY   (Singapore)

^b SINGAPORE GENERAL HOSPITAL   (Singapore)

^c DUKE NUS MEDICAL SCHOOL   (Singapore)

^d Instituto de Biomedicina (IBIOMED) and Department of Molecular Biology   (Spain)

^e NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^f INSTITUTE OF MEDICAL BIOLOGY   (Singapore)

^g GENOME INSTITUTE OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROTEIN SIAH1; PROTEIN TAP73; REGULATOR PROTEIN; TRANSCRIPTOME; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; HIF1A PROTEIN, HUMAN; NUCLEAR PROTEIN; PROTEIN BINDING; SEVEN IN ABSENTIA PROTEINS; TUMOR SUPPRESSOR PROTEIN; TUMOR SUPPRESSOR PROTEIN P73; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ANGIOGENIC GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER SIZE; CARCINOGENESIS; CONTROLLED STUDY; FEMALE; GENE; GENE EXPRESSION; GENETIC REGULATION; HUMAN; HUMAN CELL; HYPOXIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; PROTEIN STABILITY; PROTEIN TARGETING; TUMOR VASCULARIZATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; C57BL MOUSE; CELL HYPOXIA; CELL TRANSFORMATION; GENE EXPRESSION REGULATION; GENETICS; HCT116 CELL LINE; KNOCKOUT MOUSE; METABOLISM; NEOPLASM; NEOVASCULARIZATION (PATHOLOGY); SCID MOUSE; TUMOR CELL LINE; UBIQUITINATION; VASCULARIZATION;

ANIMALS; CELL HYPOXIA; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HCT116 CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, SCID; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; NUCLEAR PROTEINS; PROTEIN BINDING; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84925937153     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb3130     Document Type: Article

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