TAp73 suppresses tumor angiogenesis through repression of proangiogenic cytokines and HIF-1α activity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 1, 2015, Pages 220-225

  Stantic, Marina ^a   Sakil, Habib A M ^a   Zirath, Hanna ^a   Fang, Trixy ^a   Sanz, Gema ^a   Fernandez Woodbridge, Alejandro ^a   Marin, Ana ^a   Susanto, Evelyn ^a   Mak, Tak W ^b   Henriksson, Marie Arsenian ^a   Wilhelm, Margareta T ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b University Health Network   (Canada)

Author keywords

Angiogenesis; HIF 1 alpha; p73; Tumor microenvironment; Vascular permeability

Indexed keywords

CYTOKINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROTEIN P73; TUMOR SUPPRESSOR PROTEIN; TUMOR SUPPRESSOR PROTEIN TAP73; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN; ANGIOGENIC FACTOR; CADHERIN; DNA BINDING PROTEIN; ISOPROTEIN; NUCLEAR PROTEIN; TUMOR SUPPRESSOR PROTEIN P73;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL PERMEABILITY; BREAST CANCER; CANCER GROWTH; CANCER INHIBITION; CELL JUNCTION; CONTROLLED STUDY; CORRELATIONAL STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; UPREGULATION; ANGIOGENESIS; ANIMAL; BREAST TUMOR; CELL HYPOXIA; CELL PROLIFERATION; FEMALE; GENE EXPRESSION REGULATION; GENETICS; INFLAMMATION; METABOLISM; PATHOLOGY; PERMEABILITY; TRANSFORMED CELL LINE; VASCULARIZATION; ZEBRA FISH;

ANGIOGENESIS INDUCING AGENTS; ANIMALS; BREAST NEOPLASMS; CADHERINS; CELL HYPOXIA; CELL LINE, TRANSFORMED; CELL PROLIFERATION; CYTOKINES; DNA-BINDING PROTEINS; ENDOTHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INFLAMMATION; MICE; NEOVASCULARIZATION, PATHOLOGIC; NEOVASCULARIZATION, PHYSIOLOGIC; NUCLEAR PROTEINS; PERMEABILITY; PROTEIN ISOFORMS; TUMOR SUPPRESSOR PROTEINS; ZEBRAFISH;

EID: 84920425095     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1421697112     Document Type: Article

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