Loss of the polarity protein PAR3 activates STAT3 signaling via an atypical protein Kinase C (aPKC)/NF-κB/interleukin-6 (IL-6) axis in mouse mammary cells

Journal of Biological Chemistry

Volumn 290, Issue 13, 2015, Pages 8457-8468

  Guyer, Richard A ^a,b   Macara, Ian G ^a  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINS; TUMORS;

MAMMARY TUMORS; POLARITY PROTEINS; PROTEIN KINASE C; TUMOR PROGRESSIONS; TUMOR SUPPRESSORS;

CELL SIGNALING;

CELL PROTEIN; GLYCOPROTEIN GP 130; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; PROTEIN KINASE C; PROTEIN PAR3; STAT3 PROTEIN; UNCLASSIFIED DRUG; CELL ADHESION MOLECULE; IL6ST PROTEIN, MOUSE; PARD3 PROTEIN, MOUSE; PKC-3 PROTEIN; STAT3 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; AUTOCRINE EFFECT; BREAST CELL; BREAST EPITHELIUM CELL; CARCINOGENICITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE SILENCING; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; ANIMAL; C3H MOUSE; CELL CULTURE; CYTOLOGY; EPITHELIUM CELL; FEMALE; GENETICS; METABOLISM; PHOSPHORYLATION; PROTEIN PROCESSING; UDDER;

ANIMALS; AUTOCRINE COMMUNICATION; CELL ADHESION MOLECULES; CELLS, CULTURED; CYTOKINE RECEPTOR GP130; ENZYME ACTIVATION; EPITHELIAL CELLS; FEMALE; INTERLEUKIN-6; MAMMARY GLANDS, ANIMAL; MICE, INBRED C3H; NF-KAPPA B; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN PROCESSING, POST-TRANSLATIONAL; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 84925815779     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.621011     Document Type: Article

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