메뉴 건너뛰기




Volumn 17, Issue 1, 2010, Pages 81-88

High expression of atypical protein kinase C λ/ι in gastric cancer as a prognostic factor for recurrence

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; FLUOROURACIL; PROTEIN KINASE C IOTA; PROTEIN KINASE C LAMBDA; UFT; UVOMORULIN;

EID: 74649083141     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-009-0708-x     Document Type: Article
Times cited : (55)

References (46)
  • 1
    • 33645526144 scopus 로고    scopus 로고
    • Cancer statistics, 2006
    • 10.3322/canjclin.56.2.106 16514137
    • A Jemal R Siegel E Ward MJ Thun 2006 Cancer Statistics, 2006 CA Cancer J Clin. 56 106 130 10.3322/canjclin.56.2.106 16514137
    • (2006) CA Cancer J Clin. , vol.56 , pp. 106-130
    • Jemal, A.1    Siegel, R.2    Ward, E.3    Thun, M.J.4
  • 2
    • 3042778739 scopus 로고    scopus 로고
    • Differential trends in the intestinal and diffuse types of gastric carcinoma in the United States, 1973-2000: Increase in the signet ring cell type
    • 15214826
    • DE Henson C Dittus M Younes H Nguyen J Albores-Saavedra 2004 Differential trends in the intestinal and diffuse types of gastric carcinoma in the United States, 1973-2000: increase in the signet ring cell type Arch Pathol Lab Med 128 765 770 15214826
    • (2004) Arch Pathol Lab Med , vol.128 , pp. 765-770
    • Henson, D.E.1    Dittus, C.2    Younes, M.3    Nguyen, H.4    Albores-Saavedra, J.5
  • 4
    • 13844250344 scopus 로고    scopus 로고
    • Epidemiology and long term survival of gastric carcinoma in the French district of Finistere between 1984 and 1995
    • 15738892
    • J Faycal C Bessaguet JB Nousbaum, et al. 2005 Epidemiology and long term survival of gastric carcinoma in the French district of Finistere between 1984 and 1995 Gastroenterol Clin Biol. 29 23 32 15738892
    • (2005) Gastroenterol Clin Biol. , vol.29 , pp. 23-32
    • Faycal, J.1    Bessaguet, C.2    Nousbaum, J.B.3
  • 5
    • 0034478138 scopus 로고    scopus 로고
    • Screening for gastric cancer in Japan
    • 10.1007/PL00011692 11984703
    • Y Tsubono S Hisamichi 2000 Screening for gastric cancer in Japan Gastric Cancer 3 9 18 10.1007/PL00011692 11984703
    • (2000) Gastric Cancer , vol.3 , pp. 9-18
    • Tsubono, Y.1    Hisamichi, S.2
  • 6
    • 40749153540 scopus 로고    scopus 로고
    • S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): A phase III trial
    • 10.1016/S1470-2045(08)70035-4 1:CAS:528:DC%2BD1cXivVaqtb4%3D 18282805
    • W Koizumi H Narahara T Hara, et al. 2008 S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): a phase III trial Lancet Oncol 9 215 221 10.1016/S1470-2045(08)70035-4 1:CAS:528:DC%2BD1cXivVaqtb4%3D 18282805
    • (2008) Lancet Oncol , vol.9 , pp. 215-221
    • Koizumi, W.1    Narahara, H.2    Hara, T.3
  • 7
    • 52049087904 scopus 로고    scopus 로고
    • Optimizing docetaxel chemotherapy in patients with cancer of the gastric and gastroesophageal junction: Evolution of the docetaxel, cisplatin, and 5-fluorouracil regimen
    • 10.1002/cncr.23661 1:CAS:528:DC%2BD1cXhtFSlur3E 18623382
    • JA Ajani 2008 Optimizing docetaxel chemotherapy in patients with cancer of the gastric and gastroesophageal junction: evolution of the docetaxel, cisplatin, and 5-fluorouracil regimen Cancer 113 945 955 10.1002/cncr.23661 1:CAS:528:DC%2BD1cXhtFSlur3E 18623382
    • (2008) Cancer , vol.113 , pp. 945-955
    • Ajani, J.A.1
  • 8
    • 0029060391 scopus 로고
    • Protein kinase C and lipid signaling for sustained cellular responses
    • 1:CAS:528:DyaK2MXlsVOqurk%3D 7737456
    • Y Nishizuka 1995 Protein kinase C and lipid signaling for sustained cellular responses FASEB J 9 484 496 1:CAS:528:DyaK2MXlsVOqurk%3D 7737456
    • (1995) FASEB J , vol.9 , pp. 484-496
    • Nishizuka, Y.1
  • 9
    • 0037287298 scopus 로고    scopus 로고
    • Protein kinase C λ/ι (PKCλ/ι: A PKC isotype essential for the development of multicellular organisms
    • DOI 10.1093/jb/mvg018
    • A Suzuki K Akimoto S Ohno 2003 Protein kinase C lambda/iota (PKClambda/iota): a PKC isotype essential for the development of multicellular organisms J Biochem 133 9 16 10.1093/jb/mvg018 1:CAS:528:DC%2BD3sXitlOkurc%3D 12761193 (Pubitemid 36240973)
    • (2003) Journal of Biochemistry , vol.133 , Issue.1 , pp. 9-16
    • Suzuki, A.1    Akimoto, K.2    Ohno, S.3
  • 10
    • 0028298476 scopus 로고
    • A new member of the third class in the protein kinase C family, PKC lambda, expressed dominantly in an undifferentiated mouse embryonal carcinoma cell line and also in many tissues and cells
    • 1:CAS:528:DyaK2cXktVeksL8%3D 7513693
    • K Akimoto K Mizuno S Osada, et al. 1994 A new member of the third class in the protein kinase C family, PKC lambda, expressed dominantly in an undifferentiated mouse embryonal carcinoma cell line and also in many tissues and cells J Biol Chem 269 12677 12683 1:CAS:528:DyaK2cXktVeksL8%3D 7513693
    • (1994) J Biol Chem , vol.269 , pp. 12677-12683
    • Akimoto, K.1    Mizuno, K.2    Osada, S.3
  • 11
    • 0035479930 scopus 로고    scopus 로고
    • Intercellular junctions and cellular polarity: The PAR-aPKC complex, a conserved core cassette playing fundamental roles in cell polarity
    • DOI 10.1016/S0955-0674(00)00264-7
    • S Ohno 2001 Intercellular junctions and cellular polarity: the Par-aPKC complex, a conserved core cassette playing fundamental roles in cell polarity Curr Opin Cell Biol 13 641 648 10.1016/S0955-0674(00)00264-7 1:CAS:528:DC%2BD3MXmsFersbk%3D 11544035 (Pubitemid 32817025)
    • (2001) Current Opinion in Cell Biology , vol.13 , Issue.5 , pp. 641-648
    • Ohno, S.1
  • 12
    • 0033547873 scopus 로고    scopus 로고
    • Protein kinase Cι activity is necessary for Bcr-Abl-mediated resistance to drug-induced apoptosis
    • DOI 10.1074/jbc.274.7.3927
    • L Jamieson L Carpenter TJ Biden AP Fields 1999 Protein kinase C iota activity is necessary for Bcr-Abl-mediated resistance to drug-induced apoptosis J Biol Chem 274 3927 3930 10.1074/jbc.274.7.3927 1:CAS:528:DyaK1MXhslahtL0%3D 9933579 (Pubitemid 29090914)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.7 , pp. 3927-3930
    • Jamieson, L.1    Carpenter, L.2    Biden, T.J.3    Fields, A.P.4
  • 13
    • 0037222950 scopus 로고    scopus 로고
    • Cell polarity: Par6, aPKC and cytoskeletal crosstalk
    • DOI 10.1016/S0955-0674(02)00005-4
    • S Etienne-Manneville A Hall 2003 Cell polarity: Par6, aPKC and cytoskeletal crosstalk Curr Opin Cell Biol 1 67 72 10.1016/S0955-0674(02)00005-4 (Pubitemid 36044717)
    • (2003) Current Opinion in Cell Biology , vol.15 , Issue.1 , pp. 67-72
    • Etienne-Manneville, S.1    Hall, A.2
  • 14
    • 0034328882 scopus 로고    scopus 로고
    • The atypical protein kinase Cs. Functional specificity mediated by specific protein adapters
    • 10.1093/embo-reports/kvd098 1:CAS:528:DC%2BD3MXjtF2hsLs%3D 11258478
    • J Moscat MT Diaz-Meco 2000 The atypical protein kinase Cs. Functional specificity mediated by specific protein adapters EMBO Rep 1 399 403 10.1093/embo-reports/kvd098 1:CAS:528:DC%2BD3MXjtF2hsLs%3D 11258478
    • (2000) EMBO Rep , vol.1 , pp. 399-403
    • Moscat, J.1    Diaz-Meco, M.T.2
  • 15
    • 0030022346 scopus 로고    scopus 로고
    • EGF or PDGF receptors activate atypical PKC lambda through phosphatidylinositol 3-kinase
    • 1:CAS:528:DyaK28XhsFGgt7k%3D 8631300
    • K Akimoto R Takahashi S Moriya, et al. 1996 EGF or PDGF receptors activate atypical PKC lambda through phosphatidylinositol 3-kinase EMBO J 15 788 798 1:CAS:528:DyaK28XhsFGgt7k%3D 8631300
    • (1996) EMBO J , vol.15 , pp. 788-798
    • Akimoto, K.1    Takahashi, R.2    Moriya, S.3
  • 16
    • 0032532270 scopus 로고    scopus 로고
    • Atypical protein kinase C lambda binds and regulates p70 S6 kinase
    • 1:CAS:528:DyaK1cXntFWntbY%3D 9761742
    • K Akimoto M Nakaya T Yamanaka, et al. 1998 Atypical protein kinase C lambda binds and regulates p70 S6 kinase Biochem J 335 417 424 1:CAS:528:DyaK1cXntFWntbY%3D 9761742
    • (1998) Biochem J , vol.335 , pp. 417-424
    • Akimoto, K.1    Nakaya, M.2    Yamanaka, T.3
  • 17
    • 33747886310 scopus 로고    scopus 로고
    • Cell signaling and function organized by PB1 domain interactions
    • DOI 10.1016/j.molcel.2006.08.002, PII S1097276506005375
    • J Moscat MT Diaz-Meco A Albert S Campuzano 2006 Cell signaling and function organized by PB1 domain interactions Mol Cell 23 631 640 10.1016/j.molcel.2006.08.002 1:CAS:528:DC%2BD28XhtVSkt73E 16949360 (Pubitemid 44292560)
    • (2006) Molecular Cell , vol.23 , Issue.5 , pp. 631-640
    • Moscat, J.1    Diaz-Meco, M.T.2    Albert, A.3    Campuzano, S.4
  • 18
    • 24744469442 scopus 로고    scopus 로고
    • Atypical protein kinase Cτ plays a critical role in human lung cancer cell growth and tumorigenicity
    • DOI 10.1074/jbc.M505402200
    • RP Regala C Weems L Jamieson JA Copland EA Thompson AP Fields 2005 Atypical protein kinase C ι plays a critical role in human lung cancer cell growth and tumorigenicity J Biol Chem. 280 31109 31115 10.1074/jbc.M505402200 1:CAS:528:DC%2BD2MXpsVCmtbg%3D 15994303 (Pubitemid 41291846)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.35 , pp. 31109-31115
    • Regala, R.P.1    Weems, C.2    Jamieson, L.3    Copland, J.A.4    Thompson, E.A.5    Fields, A.P.6
  • 19
    • 25444531988 scopus 로고    scopus 로고
    • Atypical protein kinase Cι is an oncogene in human non-small cell lung cancer
    • DOI 10.1158/0008-5472.CAN-05-2372
    • PR Roderick W Capella J Lee, et al. 2005 Atypical protein kinase C ι is an oncogene in human non-small cell lung cancer Cancer Res 65 8905 8911 10.1158/0008-5472.CAN-05-2372 (Pubitemid 41377380)
    • (2005) Cancer Research , vol.65 , Issue.19 , pp. 8905-8911
    • Regala, R.P.1    Weems, C.2    Jamieson, L.3    Khoor, A.4    Edell, E.S.5    Lohse, C.M.6    Fields, A.P.7
  • 20
    • 1242267227 scopus 로고    scopus 로고
    • Protein kinase C isoform expression in ovarian carcinoma correlates with indicators of poor prognosis
    • 1:CAS:528:DC%2BD3sXntVCjsLk%3D 12888898
    • W Weichert V Gekeler C Denkert M Dietel S Hauptmann 2003 Protein kinase C isoform expression in ovarian carcinoma correlates with indicators of poor prognosis Int J Oncol 23 633 639 1:CAS:528:DC%2BD3sXntVCjsLk%3D 12888898
    • (2003) Int J Oncol , vol.23 , pp. 633-639
    • Weichert, W.1    Gekeler, V.2    Denkert, C.3    Dietel, M.4    Hauptmann, S.5
  • 22
    • 33646418390 scopus 로고    scopus 로고
    • Integrative genomic analysis of protein kinase C (PKC) family identifies PKC iota as a biomarker and potential oncogene in ovarian carcinoma
    • 10.1158/0008-5472.CAN-05-4527 1:CAS:528:DC%2BD28XjvF2ksLc%3D 16651413
    • L Zhang J Huang N Yang, et al. 2006 Integrative genomic analysis of protein kinase C (PKC) family identifies PKC iota as a biomarker and potential oncogene in ovarian carcinoma Cancer Res 66 4627 4635 10.1158/0008-5472.CAN-05- 4527 1:CAS:528:DC%2BD28XjvF2ksLc%3D 16651413
    • (2006) Cancer Res , vol.66 , pp. 4627-4635
    • Zhang, L.1    Huang, J.2    Yang, N.3
  • 24
    • 39049087115 scopus 로고    scopus 로고
    • Correlation of aPKC-iota and E-cadherin expression with invasion and prognosis of cholangiocarcinoma
    • 18234642
    • Q Li JM Wang C Liu BL Xiao JX Lu SQ Zou 2008 Correlation of aPKC-iota and E-cadherin expression with invasion and prognosis of cholangiocarcinoma Hepatobiliary Pancreat Dis Int 7 70 75 18234642
    • (2008) Hepatobiliary Pancreat Dis Int , vol.7 , pp. 70-75
    • Li, Q.1    Wang, J.M.2    Liu, C.3    Xiao, B.L.4    Lu, J.X.5    Zou, S.Q.6
  • 26
    • 0032956497 scopus 로고    scopus 로고
    • New perspectives on mechanisms involved in generating epithelial cell polarity
    • 1:CAS:528:DyaK1MXhs1Cgu70%3D 9922368
    • C Yeaman KK Grindstaff WJ Nelson 1999 New perspectives on mechanisms involved in generating epithelial cell polarity Physiol Rev 79 73 98 1:CAS:528:DyaK1MXhs1Cgu70%3D 9922368
    • (1999) Physiol Rev , vol.79 , pp. 73-98
    • Yeaman, C.1    Grindstaff, K.K.2    Nelson, W.J.3
  • 27
    • 44449111555 scopus 로고    scopus 로고
    • Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways
    • 10.1158/0008-5472.CAN-07-2938 1:CAS:528:DC%2BD1cXlvVOitLw%3D 18483246
    • TT Onder PB Gupta SA Mani J Yang ES Lander RA Weinberg 2008 Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways Cancer Res 68 3645 3654 10.1158/0008-5472.CAN-07-2938 1:CAS:528: DC%2BD1cXlvVOitLw%3D 18483246
    • (2008) Cancer Res , vol.68 , pp. 3645-3654
    • Onder, T.T.1    Gupta, P.B.2    Mani, S.A.3    Yang, J.4    Lander, E.S.5    Weinberg, R.A.6
  • 28
    • 0031031014 scopus 로고    scopus 로고
    • Abnormal immunoreactivity of the E-cadherin-catenin complex in gastric carcinoma: Relationship with patients survival
    • 10.1016/S0016-5085(97)70218-X 1:STN:280:DyaK2s7jt12rsQ%3D%3D 8978342
    • A Jawhari S Johnson S Poole P Browne M Pignatelli MJ Farthing 1997 Abnormal immunoreactivity of the E-cadherin-catenin complex in gastric carcinoma: relationship with patients survival Gastroenterology 112 46 54 10.1016/S0016-5085(97)70218-X 1:STN:280:DyaK2s7jt12rsQ%3D%3D 8978342
    • (1997) Gastroenterology , vol.112 , pp. 46-54
    • Jawhari, A.1    Johnson, S.2    Poole, S.3    Browne, P.4    Pignatelli, M.5    Farthing, M.J.6
  • 29
    • 0033748785 scopus 로고    scopus 로고
    • Inverse expression of S100A4 and E-cadherin is associated with metastatic potential in gastric cancer
    • 1:CAS:528:DC%2BD3cXovVSgtbg%3D 11106237
    • Y Yonemura Y Endou K Kimura, et al. 2000 Inverse expression of S100A4 and E-cadherin is associated with metastatic potential in gastric cancer Clin Cancer Res. 6 4234 4242 1:CAS:528:DC%2BD3cXovVSgtbg%3D 11106237
    • (2000) Clin Cancer Res. , vol.6 , pp. 4234-4242
    • Yonemura, Y.1    Endou, Y.2    Kimura, K.3
  • 33
    • 0037106581 scopus 로고    scopus 로고
    • APKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarization
    • 10.1242/jcs.00032 1:CAS:528:DC%2BD38XnvFGns7o%3D 12186943
    • A Suzuki C Ishiyama K Hashiba M Shimizu K Ebnet S Ohno 2002 aPKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarization J Cell Sci 115 3565 3573 10.1242/jcs.00032 1:CAS:528:DC%2BD38XnvFGns7o%3D 12186943
    • (2002) J Cell Sci , vol.115 , pp. 3565-3573
    • Suzuki, A.1    Ishiyama, C.2    Hashiba, K.3    Shimizu, M.4    Ebnet, K.5    Ohno, S.6
  • 35
    • 33645746316 scopus 로고    scopus 로고
    • The PAR-aPKC system: Lessons in polarity
    • 10.1242/jcs.02898 1:CAS:528:DC%2BD28Xjs1yrsbo%3D 16525119
    • A Suzuki S Ohno 2006 The PAR-aPKC system: lessons in polarity J Cell Sci 119 979 987 10.1242/jcs.02898 1:CAS:528:DC%2BD28Xjs1yrsbo%3D 16525119
    • (2006) J Cell Sci , vol.119 , pp. 979-987
    • Suzuki, A.1    Ohno, S.2
  • 37
    • 0035900791 scopus 로고    scopus 로고
    • Protein kinase C isoforms involved in the transcriptional activation of cyclin D1 by transforming Ha-Ras
    • 10.1074/jbc.M102047200 1:CAS:528:DC%2BD3MXptlelsrg%3D 11551901
    • S Kampfer M Windegger F Hochholdinger W Schwaiger RG Pestell G Baier, et al. 2001 Protein kinase C isoforms involved in the transcriptional activation of cyclin D1 by transforming Ha-Ras J Biol Chem 276 42834 42842 10.1074/jbc.M102047200 1:CAS:528:DC%2BD3MXptlelsrg%3D 11551901
    • (2001) J Biol Chem , vol.276 , pp. 42834-42842
    • Kampfer, S.1    Windegger, M.2    Hochholdinger, F.3    Schwaiger, W.4    Pestell, R.G.5    Baier, G.6
  • 39
    • 0028810482 scopus 로고
    • Clinicopathologic evaluation of immunohistochemical E-cadherin expression in human gastric carcinomas
    • 10.1002/1097-0142(19951201)76:11<2193::AID-CNCR2820761104>3.0. CO;2-2 1:STN:280:DyaK283itlaksg%3D%3D 8635021
    • Y Shino A Watanabe Y Yamada, et al. 1995 Clinicopathologic evaluation of immunohistochemical E-cadherin expression in human gastric carcinomas Cancer 76 2193 2201 10.1002/1097-0142(19951201)76:11<2193::AID-CNCR2820761104>3.0. CO;2-2 1:STN:280:DyaK283itlaksg%3D%3D 8635021
    • (1995) Cancer , vol.76 , pp. 2193-2201
    • Shino, Y.1    Watanabe, A.2    Yamada, Y.3
  • 40
    • 0037714334 scopus 로고    scopus 로고
    • Abnormal expression of E-cadherin, beta-catenin, and c-erbB-2 in advanced gastric cancer: Its association with liver metastasis
    • 12548420
    • A Ougolkov K Yamashita V Bilim Y Takahashi M Mai T Minamoto 2003 Abnormal expression of E-cadherin, beta-catenin, and c-erbB-2 in advanced gastric cancer: its association with liver metastasis Int J Colorectal Dis 18 160 166 12548420
    • (2003) Int J Colorectal Dis , vol.18 , pp. 160-166
    • Ougolkov, A.1    Yamashita, K.2    Bilim, V.3    Takahashi, Y.4    Mai, M.5    Minamoto, T.6
  • 41
    • 0035833317 scopus 로고    scopus 로고
    • NF-κB/RelA transactivation is required for atypical protein kinase Cl-mediated cell survival
    • DOI 10.1038/sj.onc.1204607
    • Y Lu L Jamieson AR Brasier AP Fields 2001 NF-kappaB/RelA transactivation is required for atypical protein kinase C iota-mediated cell survival Oncogene 20 4777 4792 10.1038/sj.onc.1204607 1:CAS:528:DC%2BD3MXmtlCrsL0%3D 11521190 (Pubitemid 32803149)
    • (2001) Oncogene , vol.20 , Issue.35 , pp. 4777-4792
    • Lu, Y.1    Jamieson, L.2    Brasier, A.R.3    Fields, A.P.4
  • 42
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • DOI 10.1038/nrc1590
    • M Dean T Fojo S Bates 2005 Tumour stem cells and drug resistance Nat Rev Cancer 5 275 284 10.1038/nrc1590 1:CAS:528:DC%2BD2MXivVarsL4%3D 15803154 (Pubitemid 40488633)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.4 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3
  • 43
    • 34250722131 scopus 로고    scopus 로고
    • Protein kinase Cι: Human oncogene, prognostic marker and therapeutic target
    • DOI 10.1016/j.phrs.2007.04.015, PII S1043661807000886
    • AP Fields RP Regala 2007 Protein kinase C iota: human oncogene, prognostic marker and therapeutic target Pharmacol Res 55 487 497 10.1016/j.phrs.2007.04.015 1:CAS:528:DC%2BD2sXntFyhtrc%3D 17570678 (Pubitemid 46962307)
    • (2007) Pharmacological Research , vol.55 , Issue.6 , pp. 487-497
    • Fields, A.P.1    Regala, R.P.2
  • 44
    • 48649092328 scopus 로고    scopus 로고
    • Atypical protein kinase C iota expression and aurothiomalate sensitivity in human lung cancer cells
    • 10.1158/0008-5472.CAN-08-0438 1:CAS:528:DC%2BD1cXovVCnsbk%3D 18632643
    • RP Regala EA Thompson AP Fields 2008 Atypical protein kinase C iota expression and aurothiomalate sensitivity in human lung cancer cells Cancer Res 68 5888 5895 10.1158/0008-5472.CAN-08-0438 1:CAS:528:DC%2BD1cXovVCnsbk%3D 18632643
    • (2008) Cancer Res , vol.68 , pp. 5888-5895
    • Regala, R.P.1    Thompson, E.A.2    Fields, A.P.3
  • 45
    • 51349135500 scopus 로고    scopus 로고
    • Protein kinase C isozymes as therapeutic targets for treatment of human cancers
    • 10.1016/j.advenzreg.2007.11.014 1:CAS:528:DC%2BD1MXhsFGmtbrP 18167314
    • AP Fields NR Murray 2008 Protein kinase C isozymes as therapeutic targets for treatment of human cancers Adv Enzyme Regul 48 166 178 10.1016/j.advenzreg. 2007.11.014 1:CAS:528:DC%2BD1MXhsFGmtbrP 18167314
    • (2008) Adv Enzyme Regul , vol.48 , pp. 166-178
    • Fields, A.P.1    Murray, N.R.2
  • 46
    • 32944470373 scopus 로고    scopus 로고
    • A novel small-molecule inhibitor of protein kinase Cι blocks transformed growth of non-small-cell lung cancer cells
    • DOI 10.1158/0008-5472.CAN-05-3405
    • M Stallings-Mann L Jamieson RP Regala C Weems NR Murray AP Fields 2006 A novel small-molecule inhibitor of protein kinase C iota blocks transformed growth of non-small-cell lung cancer cells Cancer Res 66 1767 1774 10.1158/0008-5472.CAN-05-3405 1:CAS:528:DC%2BD28XpsVeltw%3D%3D 16452237 (Pubitemid 43259962)
    • (2006) Cancer Research , vol.66 , Issue.3 , pp. 1767-1774
    • Stailings-Mann, M.1    Jamieson, L.2    Regala, R.P.3    Weems, C.4    Murray, N.R.5    Fields, A.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.