Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects

Molecular Aspects of Medicine

Volumn 34, Issue 2-3, 2013, Pages 571-585

  Schiöth, Helgi B ^a   Roshanbin, Sahar ^a   Hägglund, Maria G A ^a   Fredriksson, Robert ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Amino acid transporter; Glutamate glutamine cycle; SLC32; SLC36; SLC38; VIAAT

Indexed keywords

4,5,6,7 TETRAHYDROISOXAZOLO[4,5 C]PYRIDIN 3 OL; AMINO ACID TRANSPORTER; ARALKYLAMINE ACETYLTRANSFERASE; BARBITURIC ACID DERIVATIVE; BENZODIAZEPINE DERIVATIVE; GABOXADOL; PROTEIN PAT1; PROTEIN PAT2; PROTEIN SLC32; PROTEIN SLC36; PROTEIN SLC38; UNCLASSIFIED DRUG; VESICULAR INHIBITORY AMINO ACID TRANSPORTER;

AMINO ACID TRANSPORT; ANXIETY; ANXIETY DISORDER; CELL VOLUME; CENTRAL NERVOUS SYSTEM; DRUG MANUFACTURE; DRUG TARGETING; EPILEPSY; EUKARYOTE; GABAERGIC TRANSMISSION; GENE; GREEN ALGA; HUMAN; INSOMNIA; LIVER; MALIGNANT NEOPLASTIC DISEASE; MOLECULAR EVOLUTION; MOLECULAR PHYLOGENY; NEUROPATHIC PAIN; NEUROTRANSMISSION; NONHUMAN; NUCLEOTIDE SEQUENCE; NUTRIENT UPTAKE; PANIC; PROTEIN ANALYSIS; PROTEIN DATABASE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; REGULATORY MECHANISM; REVIEW; SLC32A1 GENE; SLC36A1 GENE; SLC36A2 GENE; SLC36A3 GENE; SLC36A4 GENE; SLC38A1 GENE; SLC38A10 GENE; SLC38A11 GENE; SLC38A2 GENE; SLC38A3 GENE; SLC38A4 GENE; SLC38A5 GENE; SLC38A6 GENE; SLC38A7 GENE; SLC38A8 GENE; SLC38A9 GENE; STRUCTURE ANALYSIS; TISSUE DISTRIBUTION; TREATMENT INDICATION;

AMINO ACID TRANSPORT SYSTEMS, NEUTRAL; DRUG DISCOVERY; EVOLUTION, MOLECULAR; HUMANS; LIVER; MODELS, BIOLOGICAL; PHYLOGENY; REAL-TIME POLYMERASE CHAIN REACTION; SPECIES SPECIFICITY; SYMPORTERS; VESICULAR INHIBITORY AMINO ACID TRANSPORT PROTEINS;

EID: 84875161720     PISSN: 00982997     EISSN: 18729452     Source Type: Journal    
DOI: 10.1016/j.mam.2012.07.012     Document Type: Review

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