The mechanisms of Fenretinide-mediated anti-cancer activity and prevention of obesity and type-2 diabetes

Biochemical Pharmacology

Volumn 91, Issue 3, 2014, Pages 277-286

  Mody, Nimesh ^a   McIlroy, George D ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Adipogenesis; Apoptosis; Autophagy; Obesity; Reactive oxygen species; Retinoic acid; Type 2 diabetes

Indexed keywords

ANTINEOPLASTIC AGENT; CYTOCHROME P450; FENRETINIDE; PLASMA RETINOL BINDING PROTEIN; RBP4 PROTEIN, HUMAN; REACTIVE OXYGEN METABOLITE; RETINOIC ACID 4-HYDROXYLASE; RETINOL; APOPTOSIS SIGNAL REGULATING KINASE 1; CERAMIDE; DJ 1 PROTEIN; DRUG METABOLITE; GLUCOSE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LIPID; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAK; PROTEIN BCL 2; RETINOIC ACID RECEPTOR; RETINOID; RETINOL BINDING PROTEIN 4;

ANIMAL; AUTOPHAGY; BLOOD; CLINICAL TRIAL (TOPIC); DIABETES MELLITUS, TYPE 2; DRUG EFFECTS; ELECTRON TRANSPORT; HUMAN; LIPID METABOLISM; METABOLISM; OBESITY; SIGNAL TRANSDUCTION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; DRUG EFFICACY; DRUG MECHANISM; ENERGY BALANCE; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; HOMEOSTASIS; INSULIN RESISTANCE; LIPID HOMEOSTASIS; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; REVIEW;

ANIMALS; ANTINEOPLASTIC AGENTS; AUTOPHAGY; CLINICAL TRIALS AS TOPIC; CYTOCHROME P-450 ENZYME SYSTEM; DIABETES MELLITUS, TYPE 2; ELECTRON TRANSPORT; FENRETINIDE; HUMANS; LIPID METABOLISM; OBESITY; REACTIVE OXYGEN SPECIES; RETINOL-BINDING PROTEINS, PLASMA; SIGNAL TRANSDUCTION; VITAMIN A;

EID: 84925736785     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2014.07.012     Document Type: Note

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