Induction and intracellular localization of Nur77 dictate fenretinide-induced apoptosis of human liver cancer cells

Biochemical Pharmacology

Volumn 79, Issue 7, 2010, Pages 948-954

  Yang, Hui ^a,b,c   Bushue, Nathan ^a   Bu, Pengli ^a   Yvonne Wan, Yu Jui ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b GUANGZHOU MEDICAL UNIVERSITY   (China)

^c GUANGZHOU FIRST PEOPLE'S HOSPITAL   (China)

Author keywords

Apoptosis; Fenretinide; Nuclear receptor; Nur77; Retinoids; ROS

Indexed keywords

CASPASE 3; FENRETINIDE; NUCLEAR RECEPTOR NUR77; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; MESSENGER RNA; NR4A1 PROTEIN, HUMAN; RETINOIC ACID RECEPTOR; RETINOIC ACID RECEPTOR BETA;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL DIFFERENTIATION; CELL NUCLEUS; CELL STRAIN HEPG2; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; HUMAN; HUMAN CELL; LIVER CANCER; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; DRUG EFFECT; GENETICS; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; FENRETINIDE; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MITOCHONDRIA; NUCLEAR RECEPTOR SUBFAMILY 4, GROUP A, MEMBER 1; REACTIVE OXYGEN SPECIES; RECEPTORS, RETINOIC ACID; RNA, MESSENGER;

EID: 77449127144     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2009.11.004     Document Type: Article

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