Secretion of n-(4-hydroxyphenyl) retinamide-retinol-binding protein from liver parenchymal cells: Evidence for reduced affinity of the complex for transthyretin

International Journal of Cancer

Volumn 71, Issue 4, 1997, Pages 654-659

  Holven, Kirsten B ^a   Natarajan, Vasanti ^a   Gundersen, Thomas E ^a   Moskaug, Jan Øivind ^a   Norum, Kaare R ^a   Blomhoff, Rune ^a  

^a UNIVERSITY OF OSLO   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

FENRETINIDE; PREALBUMIN; RETINOL; RETINOL BINDING PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIET; DRUG BINDING; HEPATOMA CELL; HUMAN; HUMAN CELL; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; RETINOL DEFICIENCY;

ANIMALS; CARCINOMA, HEPATOCELLULAR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHYLOMICRONS; CULTURE MEDIA; DIET; FENRETINIDE; HUMANS; LIVER; LIVER NEOPLASMS; MALE; PREALBUMIN; PROTEIN BINDING; RATS; RATS, WISTAR; RETINOL-BINDING PROTEINS; VITAMIN A DEFICIENCY;

EID: 0030927103     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19970516)71:4<654::AID-IJC23>3.0.CO;2-A     Document Type: Article

References (22)

1. BERNI, R., CLERICI, M., MALPELI, G., CLERIS, L. and FORMHLLI, F., Retinoids: in vitro interaction with retinol-binding protein and influence on plasma retinol FASEB J., 7, 1179-1184 (1993).
2. BERNI, R. and FORMELLI, F., In vitro interaction of fenretinide with plasma retinol binding protein and its functional consequences. FEBS, 308, 43-45 (1992).
3. BLOMHOFF, R., (ed.), Vatamin A in health and disease. M. Dekker, New York (1994).
4. COSTA, A., DE PALO, G., DECENSI, A., FORMELLI, F., CHIESA, F., NAVA, M., CAMERINI, T., MARUBINI, E. and VERONESI, U., Retinoids in cancer chemoprevention, clinical trials with the synthetic analogue Fenretinide. Ann. N.Y. Acad. Sci., 768, 148-162 (1995).
5. DIMITROV, N.V., MEYER, C.J., PERLOFF, M., RUPPENTHAL, M.M., PHILLIPICH, M.J., GILLIAND, D., MALONE, W. and MINN, F.L., Alteration of retinolbinding-protein concentrations by the synthetic retinoid tenretinide in healthy human subjects. Amer. J. clin. Nutr., 51, 1082-1087 (1990).
6. DUELAND, S., PEDERSEN, J.I., HELGERUD, P. and DREVON, C.A., Transport of vitamin D3 from rat intestine: evidence for transfer of vitamin D3 from chylomicrons to α-globulins. J. biol. Chem., 257, 146-150 (1982).
7. FORMELLI. F., BARUA, A.B. and OLSON, J.A., Bioactivities of N-(4-hydroxyphenyl) retinamide and retinoyl β-glucuronide. FASEB J., 10, 1014-1024 (1996).
8. FORMELLI, F. CARSANA, R. and COSTA, A., N-(4-hydroxyphenyl) retinamide (4-HPR) lowers the plasma retinol level in rats. Med. Sci. Res., 15, 843-844 (1987).
9. FORMELLI, F., CARSANA, R., COSTA, A., BURANELLI, F., CAMPA, T., DOSSENA, G., MAGNI, A. and PIZZICHETTA, M., Plasma retinol level reduction by the synthetic retinoid tenretinide: a one year follow-up study of breast cancer patients. Cancer Res., 49, 6149-6152 (1989).
10. KAISER-KUPFER, M.I., PECK, G.L., CARUSO, R.C., JAFFE, M.J., BIGIOVANNI, J.J. and GROSS, E.G., Abnormal retinal function associated with Fenretinide, a synthetic retinoid. Arch. Ophthalmol., 104, 69-70 (1986).
11. KINGSTON, T.P., LOWE, N.J., WINSTON, J. and HECKENLIVELY, J., Visual and cutaneous toxicity which occurs during N-(4-hydroxyphenyl)retinamide therapy for psoriasis. Clin. exp. Dermatol., 11, 624-627 (1986).
12. MALPELI, G., FOLLI, C. and BERNI, R., Retinoid binding to retinol-binding protein and the interference willi the interaction with transthyretin. Biochim. Biophys. Acta, 1294, 48-54 (1996).
13. MARINARI, L., LENICH, CM. and ROSS, A.C., Production and secretion of retinol-bindins protein by a human hepatoma cell line. HepG2. J. Lipid Res., 28, 941-948 (1987).
14. MONACO, H.L., RIZZI, M. and CODA, A., Structure of a complex of two plasma proteins: transthyretin and retinol binding protein. Science, 268, 1039-1041 (1995).
15. MOON, R.C., THOMPSON, H.J., BECCI, P.J., GRUBBS, C.J., GANDER, R.J., NEWTON, D.L., SMITH, J.M., PHILLIPS, S.L., HENDERSON, W.R., MULLEN, L.T., BROWN, C.C. and SPORN, M.B., N-(4-hydroxyphenyl)retinamide, a new retinoid for prevention of breast cancer in the rat. Cancer Res., 39, 1339-1346 (1979).
16. ROTMENSZ, N. and 19 OTHERS, Long-term tolerability of Fenretinide (4-HPR) in breast cancer patients. Europ. J. Cancer, 27, 1127-1131 (1991).
17. SANI, B.P., Binding affinities of retinoids to their binding proteins/receptors and their biological activities. In: Livrea M.A. and Packer L. (eds.) Retinoids, Progress in research and clinical applications, pp. 237-247, M. Dekker, New York (1993).
18. SCHAEFKER, E.M., RITTER, S.J. and SMITH, J.E., N-(4-hydroxyphenyl)retinamide (Fenretinide) induces retinol-binding protein secretion from liver and accumulation in the kidneys in rats. J. Nutr., 123, 1497-1503 (1993).
19. SMITH, J.E., CARPENTER, D., GREEN, M.H. and MOON, R.C., Secretion of vitamin A and retinol-binding protein into plasma is depressed in rats by N-(hydroxyphenyl)retinamide (Fenretinide). J. Nutr., 122, 1999-2009 (1992).
20. WELSCH, C.W., DE HOGG, J.V. and MOON, R.C., Inhibition of mammary tumorigenesis in nulliparous C3H mice by chronic feeding of the synthetic retinoid N-(4-hydroxyphenyl)retinamide. Carcinogenesis, 4, 1185-1187 (1983).
21. ZANOTTI, G., MALPELI, G. and BERNI, R., The interaction of N-ethyl retinamide with plasma retinol binding protein (RBP) and the crystal structure of the retinoid-RBP complex at 1.9 Å resolution. J. biol. Chem., 268, 24873-24879 (1993).
22. ZANOTTI, G., MARCELLO, M., MALPELI, G., FOLLI, C. SARTORI, G. and BERNI, R., Crystallographic studies on complexes between retinoids and plasma retinol-bindine protein. J. biol. Chem., 269, 47;29613-29620 (1994).