Cytotoxic responses to N-(4-hydroxyphenyl)retinamide in human pancreatic cancer cells

Cancer Chemotherapy and Pharmacology

Volumn 68, Issue 2, 2011, Pages 477-487

  Messner, Maria C ^a   Cabot, Myles C ^a  

^a JOHN WAYNE CANCER INSTITUTE   (United States)

Author keywords

4 HPR; Autophagy; Ceramide; Fenretinide; Pancreatic cancer; Reactive oxygen species (ROS)

Indexed keywords

CELL PROTEIN; CERAMIDE; FENRETINIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN LC3 II; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CANCER CELL CULTURE; CELL PROLIFERATION; CELL VACUOLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG RESPONSE; DRUG SENSITIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IC 50; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; BIOLOGICAL MARKERS; CARCINOMA; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CERAMIDES; FENRETINIDE; FREE RADICAL SCAVENGERS; HUMANS; INHIBITORY CONCENTRATION 50; MAP KINASE SIGNALING SYSTEM; MICROTUBULE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; PANCREATIC NEOPLASMS; PHOSPHORYLATION; PROTEIN ISOFORMS; PROTEIN PROCESSING, POST-TRANSLATIONAL; REACTIVE OXYGEN SPECIES;

EID: 79960901066     PISSN: 03445704     EISSN: 14320843     Source Type: Journal    
DOI: 10.1007/s00280-010-1504-9     Document Type: Article

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