메뉴 건너뛰기




Volumn 10, Issue 3, 2015, Pages

Dysregulated serum IL-23 and SIRT1 activity in peripheral blood mononuclear cells of patients with rheumatoid arthritis

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 23; INTERLEUKIN 6; INTERLEUKIN 8; SIRTUIN 1; TUMOR NECROSIS FACTOR; BIOLOGICAL MARKER; IL23A PROTEIN, HUMAN; INTERLEUKIN 23P19; SIRT1 PROTEIN, HUMAN;

EID: 84925707559     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0119981     Document Type: Article
Times cited : (37)

References (57)
  • 1
    • 84874721851 scopus 로고    scopus 로고
    • Genetics and epigenetics of rheumatoid arthritis
    • PMID: 23381558
    • Viatte S, Plant D, Raychaudhuri S (2013) Genetics and epigenetics of rheumatoid arthritis. Nat Rev Rheumatol 9: 141-153. doi: 10.1038/nrrheum.2012.237 PMID: 23381558
    • (2013) Nat Rev Rheumatol , vol.9 , pp. 141-153
    • Viatte, S.1    Plant, D.2    Raychaudhuri, S.3
  • 2
    • 79960776307 scopus 로고    scopus 로고
    • Interleukin-23: A key cytokine in inflammatory diseases
    • PMID: 21585245
    • Duvallet E, Semerano L, Assier E., Falgarone G, Boissier MC (2011) Interleukin-23: a key cytokine in inflammatory diseases. Ann Med 43: 503-511. doi: 10.3109/07853890.2011.577093 PMID: 21585245
    • (2011) Ann Med , vol.43 , pp. 503-511
    • Duvallet, E.1    Semerano, L.2    Assier, E.3    Falgarone, G.4    Boissier, M.C.5
  • 3
    • 84884250248 scopus 로고    scopus 로고
    • Tristetra-prolin regulation of Interleukin 23 mRNA stability prevents a spontaneous inflammatory disease
    • PMID: 23940256
    • Molle C, Zhang T, Ysebrant de Lendonck L, Gueydan C, Andrianne M, Sherer F, et al. (2013)Tristetra-prolin regulation of interleukin 23 mRNA stability prevents a spontaneous inflammatory disease. J Exp Med 210: 1675-1684. doi: 10.1084/jem.20120707 PMID: 23940256
    • (2013) J Exp Med , vol.210 , pp. 1675-1684
    • Molle, C.1    Zhang, T.2    Ysebrant De Lendonck, L.3    Gueydan, C.4    Andrianne, M.5    Sherer, F.6
  • 4
    • 84895153556 scopus 로고    scopus 로고
    • Emerging cell and cytokine targets in rheumatoid arthritis
    • PMID: 24217582
    • Burmester GR, Feist E, Dorner T (2014) Emerging cell and cytokine targets in rheumatoid arthritis. Nat RevRheumatol 10: 77-88. doi: 10.1038/nrrheum.2013.168 PMID: 24217582
    • (2014) Nat RevRheumatol , vol.10 , pp. 77-88
    • Burmester, G.R.1    Feist, E.2    Dorner, T.3
  • 5
    • 70450189514 scopus 로고    scopus 로고
    • Monocyte derived Interleukin (IL)-23 is an important determinant of synovial IL-17A expression in rheumatoid arthritis
    • PMID: 19797506
    • Stamp LK, Easson A, Pettersson L., Highton J, Hessian PA (2009) Monocyte derived interleukin (IL)-23 is an important determinant of synovial IL-17A expression in rheumatoid arthritis. J Rheumatol 36: 2403-2408. doi: 10.3899/jrheum.081304 PMID: 19797506
    • (2009) J Rheumatol , vol.36 , pp. 2403-2408
    • Stamp, L.K.1    Easson, A.2    Pettersson, L.3    Highton, J.4    Hessian, P.A.5
  • 6
    • 77952392957 scopus 로고    scopus 로고
    • Interleukin-23 production in dendritic cells is negatively regulated by protein phosphatase 2A
    • PMID: 20404153
    • Chang J, Voorhees TJ, Liu Y, Zhao Y., Chang CH (2010) Interleukin-23 production in dendritic cells is negatively regulated by protein phosphatase 2A. Proc Natl Acad Sci USA 107: 8340-8345. doi: 10. 1073/pnas.0914703107 PMID: 20404153
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 8340-8345
    • Chang, J.1    Voorhees, T.J.2    Liu, Y.3    Zhao, Y.4    Chang, C.H.5
  • 7
    • 79952363670 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: A new and promising drug class for the treatment of arthritis?
    • PMID: 22704084
    • Toussirot E, Khan KA, Herbein G (2010) Histone deacetylase inhibitors: a new and promising drug class for the treatment of arthritis? Clin Epigenetics 1: 3-6. doi: 10.1007/s13148-010-0002-6 PMID: 22704084
    • (2010) Clin Epigenetics , vol.1 , pp. 3-6
    • Toussirot, E.1    Khan, K.A.2    Herbein, G.3
  • 8
    • 54149098343 scopus 로고    scopus 로고
    • Epigenetic modifications in rheumatoid arthritis
    • PMID: 18947370
    • Strietholt S, Maurer B, Peters M.A., Pap T., Gay S (2008) Epigenetic modifications in rheumatoid arthritis. Arthritis ResTher 10: 219. doi: 10.1186/ar2500 PMID: 18947370
    • (2008) Arthritis ResTher , vol.10 , pp. 219
    • Strietholt, S.1    Maurer, B.2    Peters, M.A.3    Pap, T.4    Gay, S.5
  • 9
    • 34247227700 scopus 로고    scopus 로고
    • Histone deacety-lase/acetylase activity in total synovial tissue derived from rheumatoid arthritis and osteoarthritis patients
    • PMID: 17393417
    • Huber LC, Brock M, Hemmatazad H., Giger OT, Moritz F, Trenkmann M, et al. (2007) Histone deacety-lase/acetylase activity in total synovial tissue derived from rheumatoid arthritis and osteoarthritis patients. Arthritis Rheum 56:1087-1093. PMID: 17393417
    • (2007) Arthritis Rheum , vol.56 , pp. 1087-1093
    • Huber, L.C.1    Brock, M.2    Hemmatazad, H.3    Giger, O.T.4    Moritz, F.5    Trenkmann, M.6
  • 10
    • 58149140055 scopus 로고    scopus 로고
    • Biological and potential therapeutic roles of sirtuin deacetylases
    • PMID: 18820996
    • Taylor DM, Maxwell MM, Luthi-Carter R, Kazantsev AG (2008) Biological and potential therapeutic roles of sirtuin deacetylases. Cell Mol Life Sci 65: 4000-4018. doi: 10.1007/s00018-008-8357-y PMID: 18820996
    • (2008) Cell Mol Life Sci , vol.65 , pp. 4000-4018
    • Taylor, D.M.1    Maxwell, M.M.2    Luthi-Carter, R.3    Kazantsev, A.G.4
  • 11
    • 61549114593 scopus 로고    scopus 로고
    • Silent information regulator, sirtuin 1, and age-related diseases
    • PMID: 19260974
    • Zeng L, Chen R, Liang F., Tsuchiya H, Murai H, Nakahashi T., et al. (2009) Silent information regulator, Sirtuin 1, and age-related diseases. Geriatr Gerontol Int 9: 7-15. doi: 10.1111/j.1447-0594.2008. 00504.x PMID: 19260974
    • (2009) Geriatr Gerontol Int , vol.9 , pp. 7-15
    • Zeng, L.1    Chen, R.2    Liang, F.3    Tsuchiya, H.4    Murai, H.5    Nakahashi, T.6
  • 12
    • 79961125549 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha-mediated cleavage and inactivation of sirt1 in human osteoarthritic chondrocytes
    • PMID: 21305533
    • Dvir-Ginzberg M, Gagarina V, Lee E.J., Booth R., Gabay O, Hall DJ (2011) Tumor necrosis factor alpha-mediated cleavage and inactivation of Sirt1 in human osteoarthritic chondrocytes. Arthritis Rheum 63: 2363-2373. doi: 10.1002/art.30279 PMID: 21305533
    • (2011) Arthritis Rheum , vol.63 , pp. 2363-2373
    • Dvir-Ginzberg, M.1    Gagarina, V.2    Lee, E.J.3    Booth, R.4    Gabay, O.5    Hall, D.J.6
  • 13
    • 84867702707 scopus 로고    scopus 로고
    • Sirtuin activators and inhibitors
    • PMID: 22730114
    • Villalba JM, Alcain FJ (2012) Sirtuin activators and inhibitors. Biofactors 38: 349-359. doi: 10.1002/ biof.1032 PMID: 22730114
    • (2012) Biofactors , vol.38 , pp. 349-359
    • Villalba, J.M.1    Alcain, F.J.2
  • 14
    • 79952364679 scopus 로고    scopus 로고
    • Histone deacetylases in viral infections
    • PMID: 22704086
    • Herbein G, Wendling D (2010) Histone deacetylases in viral infections. Clin Epigenetics 1: 13-24. doi: 10.1007/s13148-010-0003-5 PMID: 22704086
    • (2010) Clin Epigenetics , vol.1 , pp. 13-24
    • Herbein, G.1    Wendling, D.2
  • 15
    • 77953290752 scopus 로고    scopus 로고
    • SIRT1-dependent regulation of chromatin and transcription: Linking NAD(+) metabolism and signaling to the control of cellular functions
    • PMID: 19879981
    • Zhang T, Kraus WL (2010) SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functions. Biochim Biophys Acta 1804: 1666-1675. doi: 10.1016/j.bbapap.2009.10.022 PMID: 19879981
    • (2010) Biochim Biophys Acta , vol.1804 , pp. 1666-1675
    • Zhang, T.1    Kraus, W.L.2
  • 16
    • 67649201751 scopus 로고    scopus 로고
    • Bcl-3-regulated transcription from major immediate-early promoter of human cytomegalovirus in monocyte-derived macrophages
    • PMID: 19494302
    • Khan KA, Coaquette A, Davrinche C., Herbein G (2009) Bcl-3-regulated transcription from major immediate-early promoter of human cytomegalovirus in monocyte-derived macrophages. J Immunol 182: 7784-7794. doi: 10.4049/jimmunol.0803800 PMID: 19494302
    • (2009) J Immunol , vol.182 , pp. 7784-7794
    • Khan, K.A.1    Coaquette, A.2    Davrinche, C.3    Herbein, G.4
  • 17
    • 0037462825 scopus 로고    scopus 로고
    • Exogenous nef protein activates NF-kappa B, AP-1, and c-jun N-terminal kinase and stimulates HIV transcription in promono-cytic cells. Role in AIDS pathogenesis
    • PMID: 12419805
    • Varin A, Manna SK, Quivy V, Decrion A.Z., Van Lint C, Herbein G, et al. (2003) Exogenous Nef protein activates NF-kappa B, AP-1, and c-Jun N-terminal kinase and stimulates HIV transcription in promono-cytic cells. Role in AIDS pathogenesis. J BiolChem 278: 2219-2227. PMID: 12419805
    • (2003) J BiolChem , vol.278 , pp. 2219-2227
    • Varin, A.1    Manna, S.K.2    Quivy, V.3    Decrion, A.Z.4    Van Lint, C.5    Herbein, G.6
  • 18
    • 84893806758 scopus 로고    scopus 로고
    • Resveratrol, asir-tuin 1 activator, increases IL-6 production by peripheral blood mononuclear cells of patients with knee osteoarthritis
    • PMID: 23844973
    • Wendling D, Abbas W, Godfrin-Valnet M, Guillot X., Khan KA, Cedoz JP, et al. (2013) Resveratrol, asir-tuin 1 activator, increases IL-6 production by peripheral blood mononuclear cells of patients with knee osteoarthritis. Clin Epigenetics 5: 10. doi: 10.1186/1868-7083-5-10 PMID: 23844973
    • (2013) Clin Epigenetics , vol.5 , pp. 10
    • Wendling, D.1    Abbas, W.2    Godfrin-Valnet, M.3    Guillot, X.4    Khan, K.A.5    Cedoz, J.P.6
  • 19
    • 84881595671 scopus 로고    scopus 로고
    • Imbalance between HAT and HDAC activities in the PBMCs of patients with ankylosing spondylitis or rheumatoid arthritis and influence of HDAC inhibitors on TNF alpha production
    • PMID: 24039666
    • Toussirot E, Abbas W, Khan K.A., Tissot M., Jeudy A, Baud L, et al. (2013) Imbalance between HAT and HDAC activities in the PBMCs of patients with ankylosing spondylitis or rheumatoid arthritis and influence of HDAC inhibitors on TNF alpha production. PLoS One 8: e70939. doi: 10.1371/journal.pone. 0070939 PMID: 24039666
    • (2013) PLoS One , vol.8
    • Toussirot, E.1    Abbas, W.2    Khan, K.A.3    Tissot, M.4    Jeudy, A.5    Baud, L.6
  • 20
    • 84927690742 scopus 로고    scopus 로고
    • Sirt1 activity in peripheral blood mononuclear cells from patients with rheumatoid arthritis
    • PMID: 24746477
    • Wendling D, Vidon C, Abbas W., Guillot X, Toussirot E, Herbein G (2014) Sirt1 activity in peripheral blood mononuclear cells from patients with rheumatoid arthritis. Joint Bone Spine 81: 462-463. doi: 10. 1016/j.jbspin.2014.02.006 PMID: 24746477
    • (2014) Joint Bone Spine , vol.81 , pp. 462-463
    • Wendling, D.1    Vidon, C.2    Abbas, W.3    Guillot, X.4    Toussirot, E.5    Herbein, G.6
  • 21
    • 85027953113 scopus 로고    scopus 로고
    • Increased apoptotic chondrocytes in articular cartilage from adult heterozygous SirT1 mice
    • PMID: 22258484
    • Gabay O, Oppenheimer H, Meir H., Zaal K, Sanchez C, Dvir-Ginzberg M (2012) Increased apoptotic chondrocytes in articular cartilage from adult heterozygous SirT1 mice. Ann Rheum Dis 71: 613-616. doi: 10.1136/ard.2011.200504 PMID: 22258484
    • (2012) Ann Rheum Dis , vol.71 , pp. 613-616
    • Gabay, O.1    Oppenheimer, H.2    Meir, H.3    Zaal, K.4    Sanchez, C.5    Dvir-Ginzberg, M.6
  • 23
    • 80052453175 scopus 로고    scopus 로고
    • SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance
    • PMID: 21742641
    • Niederer F, Ospelt C, Brentano F., Hottiger MO, Gay RE, Gay S, et al. (2011) SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance. Ann Rheum Dis 70: 1866-1873. doi: 10.1136/ard.2010.148957 PMID: 21742641
    • (2011) Ann Rheum Dis , vol.70 , pp. 1866-1873
    • Niederer, F.1    Ospelt, C.2    Brentano, F.3    Hottiger, M.O.4    Gay, R.E.5    Gay, S.6
  • 24
    • 84894703144 scopus 로고    scopus 로고
    • Sirtuin-1 is a nutrient-dependent modulator of inflammation
    • PMID: 23805409
    • Kotas ME, Gorecki MC, Gillum MP(2013)Sirtuin-1 is a nutrient-dependent modulator of inflammation. Adipocyte 2: 113-118. doi: 10.4161/adip.23437 PMID: 23805409
    • (2013) Adipocyte , vol.2 , pp. 113-118
    • Kotas, M.E.1    Gorecki, M.C.2    Gillum, M.P.3
  • 25
    • 84884732385 scopus 로고    scopus 로고
    • CD56+ monocytes have a dysregulated cytokine response to lipopolysaccharide and accumulate in rheumatoid arthritis and immunosenescence
    • PMID: 24286519
    • Krasselt M, Baerwald C, Wagner U., Rossol M (2013) CD56+ monocytes have a dysregulated cytokine response to lipopolysaccharide and accumulate in rheumatoid arthritis and immunosenescence. Arthritis ResTher 15: R139. doi: 10.1186/ar4321 PMID: 24286519
    • (2013) Arthritis ResTher , vol.15 , pp. R139
    • Krasselt, M.1    Baerwald, C.2    Wagner, U.3    Rossol, M.4
  • 26
    • 40949123149 scopus 로고    scopus 로고
    • Activation of innate immunity system during aging: Nf-kB signaling is the molecular culprit of inflamm-aging
    • PMID: 17964225
    • Salminen A, Huuskonen J, Ojala J., Kauppinen A, Kaarniranta K, Suuronen T (2008) Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging. Ageing Res Rev 7: 83-105. PMID: 17964225
    • (2008) Ageing Res Rev , vol.7 , pp. 83-105
    • Salminen, A.1    Huuskonen, J.2    Ojala, J.3    Kauppinen, A.4    Kaarniranta, K.5    Suuronen, T.6
  • 27
    • 84869412264 scopus 로고    scopus 로고
    • Sirt1: Def-eating senescence?
    • PMID: 22983125
    • Fusco S, Maulucci G, Pani G (2012) Sirt1: def-eating senescence? Cell Cycle 11: 4135-4146. doi: 10. 4161/cc.22074 PMID: 22983125
    • (2012) Cell Cycle , vol.11 , pp. 4135-4146
    • Fusco, S.1    Maulucci, G.2    Pani, G.3
  • 28
    • 3242719545 scopus 로고    scopus 로고
    • Modulation of NF-kap-paB-dependent transcription and cell survival by the SIRT1 deacetylase
    • PMID: 15152190
    • Yeung F, Hoberg JE, Ramsey C.S., Keller MD, Jones DR, Frye RA, et al. (2004) Modulation of NF-kap-paB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBOJ 23:2369-2380. PMID: 15152190
    • (2004) EMBOJ , vol.23 , pp. 2369-2380
    • Yeung, F.1    Hoberg, J.E.2    Ramsey, C.S.3    Keller, M.D.4    Jones, D.R.5    Frye, R.A.6
  • 29
    • 0034802887 scopus 로고    scopus 로고
    • The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression
    • PMID: 11564889
    • Ashburner BP, Westerheide SD, Baldwin AS Jr (2001) The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. Mol Cell Biol 21: 7065-7077. PMID: 11564889
    • (2001) Mol Cell Biol , vol.21 , pp. 7065-7077
    • Ashburner, B.P.1    Westerheide, S.D.2    Baldwin, A.S.3
  • 31
    • 49049103008 scopus 로고    scopus 로고
    • IL-23 induces receptor activator of NF-kappaB ligand expression on CD4+ T cells and promotes osteoclastogenesis in an autoimmune arthritis model
    • PMID: 18606706
    • Ju JH, Cho ML, Moon Y.M., Oh HJ, Park JS, Yoon CH, et al. (2008) IL-23 induces receptor activator of NF-kappaB ligand expression on CD4+ T cells and promotes osteoclastogenesis in an autoimmune arthritis model. J Immunol 181:1507-1518. PMID: 18606706
    • (2008) J Immunol , vol.181 , pp. 1507-1518
    • Ju, J.H.1    Cho, M.L.2    Moon, Y.M.3    Oh, H.J.4    Park, J.S.5    Yoon, C.H.6
  • 32
    • 84863115908 scopus 로고    scopus 로고
    • Cathepsin cleavage of sirtuin 1 in endothelial progenitor cells mediates stress-induced premature senescence
    • PMID: 22234173
    • Chen J, Xavier S, Moskowitz-Kassai E, Chen R., Lu CY, Sanduski K, et al. (2012) Cathepsin cleavage of sirtuin 1 in endothelial progenitor cells mediates stress-induced premature senescence. Am J Pathol 180: 973-983. doi: 10.1016/j.ajpath.2011.11.033 PMID: 22234173
    • (2012) Am J Pathol , vol.180 , pp. 973-983
    • Chen, J.1    Xavier, S.2    Moskowitz-Kassai, E.3    Chen, R.4    Lu, C.Y.5    Sanduski, K.6
  • 33
    • 84859822652 scopus 로고    scopus 로고
    • Sirtuin inhibition attenuates the production of inflammatory cytokines in lipopolysaccharide-stimulated macrophages
    • PMID: 22469470
    • Fernandes CA, Fievez L, Neyrinck A.M., Delzenne NM, Bureau F, Vanbever R (2012) Sirtuin inhibition attenuates the production of inflammatory cytokines in lipopolysaccharide-stimulated macrophages. Biochem Biophys Res Commun 420: 857-861. doi: 10.1016/j.bbrc.2012.03.088 PMID: 22469470
    • (2012) Biochem Biophys Res Commun , vol.420 , pp. 857-861
    • Fernandes, C.A.1    Fievez, L.2    Neyrinck, A.M.3    Delzenne, N.M.4    Bureau, F.5    Vanbever, R.6
  • 34
    • 84867407211 scopus 로고    scopus 로고
    • Sirtuin 1 is a key regulator of the interleukin-12 p70/Interleukin-23 balance in human dendritic cells
    • PMID: 22893703
    • Alvarez Y, Rodriguez M, Municio C., Hugo E, Alonso S, Ibarrola N., et al. (2012) Sirtuin 1 is a key regulator of the interleukin-12 p70/interleukin-23 balance in human dendritic cells. J Biol Chem 287: 35689-35701. doi: 10.1074/jbc.M112.391839 PMID: 22893703
    • (2012) J Biol Chem , vol.287 , pp. 35689-35701
    • Alvarez, Y.1    Rodriguez, M.2    Municio, C.3    Hugo, E.4    Alonso, S.5    Ibarrola, N.6
  • 35
    • 79251554670 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors impair innate immune responses to toll-like receptor agonists and to infection
    • PMID: 20956800
    • Roger T, Lugrin J, Le Roy D, Goy G, Mombelli M., Koessler T, et al. (2011) Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection. Blood 117: 1205-1217. doi: 10.1182/blood-2010-05-284711 PMID: 20956800
    • (2011) Blood , vol.117 , pp. 1205-1217
    • Roger, T.1    Lugrin, J.2    Le Roy, D.3    Goy, G.4    Mombelli, M.5    Koessler, T.6
  • 36
    • 80053428068 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors impair antibacterial defenses of macrophages
    • PMID: 21921209
    • Mombelli M, Lugrin J, Rubino I., Chanson AL, Giddey M, Calandra T, et al (2011) Histone deacetylase inhibitors impair antibacterial defenses of macrophages. J Infect Dis 204: 1367-1374. doi: 10.1093/ infdis/jir553 PMID: 21921209
    • (2011) J Infect Dis , vol.204 , pp. 1367-1374
    • Mombelli, M.1    Lugrin, J.2    Rubino, I.3    Chanson, A.L.4    Giddey, M.5    Calandra, T.6
  • 37
    • 84863395477 scopus 로고    scopus 로고
    • Histone deacetylases are dysregulated in rheumatoid arthritis and a novel histone deacetylase 3-selective inhibitor reduces inter-Leukin-6 production by peripheral blood mononuclear cells from rheumatoid arthritis patients
    • PMID: 21952924
    • Gillespie J, Savic S, Wong C., Hempshall A, Inman M, Emery P., et al (2012) Histone deacetylases are dysregulated in rheumatoid arthritis and a novel histone deacetylase 3-selective inhibitor reduces inter-leukin-6 production by peripheral blood mononuclear cells from rheumatoid arthritis patients. Arthritis Rheum 64: 418-422. doi: 10.1002/art.33382 PMID: 21952924
    • (2012) Arthritis Rheum , vol.64 , pp. 418-422
    • Gillespie, J.1    Savic, S.2    Wong, C.3    Hempshall, A.4    Inman, M.5    Emery, P.6
  • 38
    • 79955552937 scopus 로고    scopus 로고
    • Safety and efficacy of an oral histone deacetylase inhibitor in systemic-onset juvenile idiopathic arthritis
    • PMID: 21538322
    • Vojinovic J, Damjanov N, D'Urzo C, Furlan A, Susic G., Pasic S, et al. (2011) Safety and efficacy of an oral histone deacetylase inhibitor in systemic-onset juvenile idiopathic arthritis. Arthritis Rheum 63: 1452-1458. doi: 10.1002/art.30238 PMID: 21538322
    • (2011) Arthritis Rheum , vol.63 , pp. 1452-1458
    • Vojinovic, J.1    Damjanov, N.2    D'Urzo, C.3    Furlan, A.4    Susic, G.5    Pasic, S.6
  • 39
    • 77951925741 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue
    • PMID: 20100935
    • Grabiec AM, Krausz S, de Jager W, Burakowski T, Groot D., Sanders ME, et al. (2010) Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue. J Immunol 184: 2718-2728. doi: 10.4049/jimmunol.0901467 PMID: 20100935
    • (2010) J Immunol , vol.184 , pp. 2718-2728
    • Grabiec, A.M.1    Krausz, S.2    De Jager, W.3    Burakowski, T.4    Groot, D.5    Sanders, M.E.6
  • 40
    • 0037022598 scopus 로고    scopus 로고
    • The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits anti inflammatory properties via suppression of cytokines
    • PMID: 11867742
    • Leoni F, Zaliani A, Bertolini G., Porro G, Pagani P, Pozzi P., et al (2002) The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits anti inflammatory properties via suppression of cytokines. Proc Natl Acad Sci U S A 99: 2995-3000. PMID: 11867742
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 2995-3000
    • Leoni, F.1    Zaliani, A.2    Bertolini, G.3    Porro, G.4    Pagani, P.5    Pozzi, P.6
  • 42
    • 58349087850 scopus 로고    scopus 로고
    • Abundant expression of the inter-Leukin (IL)23 subunit p19, but low levels of bioactive IL23 in the rheumatoid synovium: Differential expression and toll-like receptor-(TLR) dependent regulation of the IL23subunits, p19and p40, in rheumatoid arthritis
    • PMID: 18276743
    • Brentano F, Ospelt C, Stanczyk J., Gay RE, Gay S, Kyburz D (2009) Abundant expression of the inter-leukin (IL)23 subunit p19, but low levels of bioactive IL23 in the rheumatoid synovium: differential expression and Toll-like receptor-(TLR) dependent regulation of the IL23subunits, p19and p40, in rheumatoid arthritis. Ann Rheum Dis 68: 143-150. doi: 10.1136/ard.2007.082081 PMID: 18276743
    • (2009) Ann Rheum Dis , vol.68 , pp. 143-150
    • Brentano, F.1    Ospelt, C.2    Stanczyk, J.3    Gay, R.E.4    Gay, S.5    Kyburz, D.6
  • 43
    • 80055113353 scopus 로고    scopus 로고
    • Activation of sirt1 by resveratrol inhibits TNF-alpha induced inflammation in fibroblasts
    • PMID: 22069489
    • Zhu X, Liu Q, Wang M., Liang M, Yang X, Xu X., et al. (2011) Activation of Sirt1 by resveratrol inhibits TNF-alpha induced inflammation in fibroblasts. PLoS One 6: e27081. doi: 10.1371/journal.pone. 0027081 PMID: 22069489
    • (2011) PLoS One , vol.6
    • Zhu, X.1    Liu, Q.2    Wang, M.3    Liang, M.4    Yang, X.5    Xu, X.6
  • 44
    • 63349108526 scopus 로고    scopus 로고
    • Anti-inflammatory mechanisms of resveratrol in activated HMC-1 cells: Pivotal roles of NF-kappaB and MAPK
    • PMID: 19416633
    • Kang OH, Jang HJ, Chae H.S., Oh YC, Choi JG, Lee YS, et al. (2009) Anti-inflammatory mechanisms of resveratrol in activated HMC-1 cells: pivotal roles of NF-kappaB and MAPK. Pharmacol Res 59: 330-337. doi: 10.1016/j.phrs.2009.01.009 PMID: 19416633
    • (2009) Pharmacol Res , vol.59 , pp. 330-337
    • Kang, O.H.1    Jang, H.J.2    Chae, H.S.3    Oh, Y.C.4    Choi, J.G.5    Lee, Y.S.6
  • 45
    • 77957879962 scopus 로고    scopus 로고
    • Increased Interleukin 21 (IL-21) and IL-23 are associated with increased disease activity and with radiographic status in patients with early rheumatoid arthritis
    • PMID: 20682664
    • Rasmussen TK, Andersen T, Hvid M., Hetland ML, Horslev-Petersen K, Stengaard-Pedersen K, et al. (2010) Increased interleukin 21 (IL-21) and IL-23 are associated with increased disease activity and with radiographic status in patients with early rheumatoid arthritis. J Rheumatol 37: 2014-2020. doi: 10.3899/jrheum.100259 PMID: 20682664
    • (2010) J Rheumatol , vol.37 , pp. 2014-2020
    • Rasmussen, T.K.1    Andersen, T.2    Hvid, M.3    Hetland, M.L.4    Horslev-Petersen, K.5    Stengaard-Pedersen, K.6
  • 46
    • 77949444874 scopus 로고    scopus 로고
    • Systemic levels of IL-23 are strongly associated with disease activity in rheumatoid arthritis but not spondylarthritis
    • PMID: 19196728
    • Melis L, Vandooren B, Kruithof E., Jacques P, De Vos M, Mielants H, et al. (2010) Systemic levels of IL-23 are strongly associated with disease activity in rheumatoid arthritis but not spondylarthritis. Ann Rheum Dis 69: 618-623. doi: 10.1136/ard.2009.107649 PMID: 19196728
    • (2010) Ann Rheum Dis , vol.69 , pp. 618-623
    • Melis, L.1    Vandooren, B.2    Kruithof, E.3    Jacques, P.4    De Vos, M.5    Mielants, H.6
  • 47
    • 79955591489 scopus 로고    scopus 로고
    • Age related changes in NAD+metabolism oxidative stress and sirt1 activity in wistar rats
    • PMID: 21541336
    • Braidy N, Guillemin GJ, Mansour H, Chan-Ling T, Poljak A., Grant R (2011) Age related changes in NAD+metabolism oxidative stress and Sirt1 activity in wistar rats. PLoS One 6:e19194 doi: 10.1371/journal.pone.0019194 PMID: 21541336
    • (2011) PLoS One , vol.6
    • Braidy, N.1    Guillemin, G.J.2    Mansour, H.3    Chan-Ling, T.4    Poljak, A.5    Grant, R.6
  • 48
    • 73949153257 scopus 로고    scopus 로고
    • Aging-dependent upregulation of IL-23p19 gene expression in dendritic cells is associated with differential transcription factor binding and histone modifications
    • PMID: 19624579
    • El Mezayen R, El Gazzar M, Myer R, High KP (2009) Aging-dependent upregulation of IL-23p19 gene expression in dendritic cells is associated with differential transcription factor binding and histone modifications. Aging Cell 8:553-565 doi: 10.1111/j.1474-9726.2009.00502.x PMID: 19624579
    • (2009) Aging Cell , vol.8 , pp. 553-565
    • El Mezayen, R.1    El Gazzar, M.2    Myer, R.3    High, K.P.4
  • 49
    • 84873258877 scopus 로고    scopus 로고
    • Age-related dysregulation of inflammation and innate immunity: Lessons learned from rodent models
    • PMID: 22396887
    • Brubaker AL, Palmer JL, Kovacs EJ (2011) Age-related dysregulation of inflammation and innate immunity: lessons learned from rodent models. Aging Dis 2:346-360. PMID: 22396887
    • (2011) Aging Dis , vol.2 , pp. 346-360
    • Brubaker, A.L.1    Palmer, J.L.2    Kovacs, E.J.3
  • 50
    • 57149099029 scopus 로고    scopus 로고
    • Blocking TH17-polarizing cytokines by histone deacetylase inhibitors in vitro and in vivo
    • PMID: 18780875
    • Bosisio D, Vulcano M, Del P.A., Sironi M., Salvi V, Salogni L, et al. (2008) Blocking TH17-polarizing cytokines by histone deacetylase inhibitors in vitro and in vivo. J Leukoc Biol 84: 1540-1548. doi: 10.1189/ jlb.0708401 PMID: 18780875
    • (2008) J Leukoc Biol , vol.84 , pp. 1540-1548
    • Bosisio, D.1    Vulcano, M.2    Del, P.A.3    Sironi, M.4    Salvi, V.5    Salogni, L.6
  • 51
    • 84857774124 scopus 로고    scopus 로고
    • The IL23/Th17 pathway as a therapeutic target in chronic inflammatory diseases
    • PMID: 22280236
    • Toussirot E (2012) The IL23/Th17 pathway as a therapeutic target in chronic inflammatory diseases. Inflamm Allergy Drug Targets 11:159-168. PMID: 22280236
    • (2012) Inflamm Allergy Drug Targets , vol.11 , pp. 159-168
    • Toussirot, E.1
  • 52
    • 84871737782 scopus 로고    scopus 로고
    • Sirtuin 1 enzymatic activity is required for cartilage homeostasis in vivo in a mouse model
    • PMID: 23124828
    • Gabay O, Sanchez C, Dvir-Ginzberg M, Gagarina V., Zaal KJ, Song Y, et al. (2013) Sirtuin 1 enzymatic activity is required for cartilage homeostasis in vivo in a mouse model. Arthritis Rheum 65: 159-166. doi: 10.1002/art.37750 PMID: 23124828
    • (2013) Arthritis Rheum , vol.65 , pp. 159-166
    • Gabay, O.1    Sanchez, C.2    Dvir-Ginzberg, M.3    Gagarina, V.4    Zaal, K.J.5    Song, Y.6
  • 53
    • 77951717549 scopus 로고    scopus 로고
    • Sirt1 enhances survival of human osteoarthritic chondrocytes by repressing protein tyrosine phosphatase 1B and activating the insulin-like growth factor receptor pathway
    • PMID: 20131294
    • Gagarina V, Gabay O, Dvir-Ginzberg M, Lee E.J., Brady JK, Quong MJ, et al. (2010) Sirt1 enhances survival of human osteoarthritic chondrocytes by repressing protein tyrosine phosphatase 1B and activating the insulin-like growth factor receptor pathway. Arthritis Rheum 62: 1383-1392. doi: 10.1002/art. 27369 PMID: 20131294
    • (2010) Arthritis Rheum , vol.62 , pp. 1383-1392
    • Gagarina, V.1    Gabay, O.2    Dvir-Ginzberg, M.3    Lee, E.J.4    Brady, J.K.5    Quong, M.J.6
  • 54
    • 84880571495 scopus 로고    scopus 로고
    • SIRT1 inhibits TNF-alpha-inducedapopto-sis of vascular adventitial fibroblasts partly through the deacetylation of FoxO1
    • PMID: 23479127
    • Wang W, Yan C, Zhang J., Lin R, Lin Q, Yang L., et al. (2013) SIRT1 inhibits TNF-alpha-inducedapopto-sis of vascular adventitial fibroblasts partly through the deacetylation of FoxO1. Apoptosis 18: 689-701. doi: 10.1007/s10495-013-0833-7 PMID: 23479127
    • (2013) Apoptosis , vol.18 , pp. 689-701
    • Wang, W.1    Yan, C.2    Zhang, J.3    Lin, R.4    Lin, Q.5    Yang, L.6
  • 55
    • 84922337401 scopus 로고    scopus 로고
    • IL-23 induces apoptosis of self-reactive thymocytes in thymic negative selection by an rorc dependent mechanism
    • Li H, Wu Q, Yang P., Cua D, Hsu HC, Mountz J (2011) IL-23 induces apoptosis of self-reactive thymocytes in thymic negative selection by an Rorc dependent mechanism. J Immunol 186:6419.
    • (2011) J Immunol , vol.186 , pp. 6419
    • Li, H.1    Wu, Q.2    Yang, P.3    Cua, D.4    Hsu, H.C.5    Mountz, J.6
  • 56
    • 25444495492 scopus 로고    scopus 로고
    • Increased spontaneous apoptosis of CD4+CD25+ T cells in patients with active rheumatoid arthritis is reduced by infliximab
    • PMID: 16126991
    • Toubi E, Kessel A, Mahmudov Z., Hallas K, Rozenbaum M, Rosner I (2005). Increased spontaneous apoptosis of CD4+CD25+ T cells in patients with active rheumatoid arthritis is reduced by infliximab. Ann NY AcadSci. 1051:506-514. PMID: 16126991
    • (2005) Ann NY AcadSci. , vol.1051 , pp. 506-514
    • Toubi, E.1    Kessel, A.2    Mahmudov, Z.3    Hallas, K.4    Rozenbaum, M.5    Rosner, I.6
  • 57
    • 84890503696 scopus 로고    scopus 로고
    • Deficient spontaneous in vitro apoptosis and increased tmTNF reverse signaling-induced apoptosis of monocytes predict suboptimal therapeutic response of rheumatoid arthritis to TNF inhibition
    • PMID: 24354986
    • Meusch U, Klingner M, Baerwald C., Rossol M, Wagner U (2013). Deficient spontaneous in vitro apoptosis and increased tmTNF reverse signaling-induced apoptosis of monocytes predict suboptimal therapeutic response of rheumatoid arthritis to TNF inhibition. Arthritis ResTher 15:R219. PMID: 24354986
    • (2013) Arthritis ResTher , vol.15 , pp. R219
    • Meusch, U.1    Klingner, M.2    Baerwald, C.3    Rossol, M.4    Wagner, U.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.