-
1
-
-
84856952418
-
Genetics and epigenetics of osteoarthritis
-
Reynard LN, Loughlin J: Genetics and epigenetics of osteoarthritis. Maturitas 2012, 71:200-204.
-
(2012)
Maturitas
, vol.71
, pp. 200-204
-
-
Reynard, L.N.1
Loughlin, J.2
-
2
-
-
84870710969
-
Epigenetics, sirtuins and osteoarthritis
-
Gabay O, Sanchez C: Epigenetics, sirtuins and osteoarthritis. Joint Bone Spine 2012, 79:570-573.
-
(2012)
Joint Bone Spine
, vol.79
, pp. 570-573
-
-
Gabay, O.1
Sanchez, C.2
-
3
-
-
79952364679
-
Histone deacetylases in viral infections
-
Herbein G, Wendling D: Histone deacetylases in viral infections. Clin Epigenetics 2010, 1:13-24.
-
(2010)
Clin Epigenetics
, vol.1
, pp. 13-24
-
-
Herbein, G.1
Wendling, D.2
-
4
-
-
58149140055
-
Biological and potential therapeutic roles of sirtuin deacetylases
-
Taylor DM, Maxwell MM, Luthi-Carter R, Kazantsev AG: Biological and potential therapeutic roles of sirtuin deacetylases. Cell Mol Life Sci 2008, 65:4000-4018.
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 4000-4018
-
-
Taylor, D.M.1
Maxwell, M.M.2
Luthi-Carter, R.3
Kazantsev, A.G.4
-
5
-
-
61549114593
-
Silent information regulator, Sirtuin 1, and age-related diseases
-
Zeng L, Chen R, Liang F, Tsuchiya H, Murai H, Nakahashi T, Iwai K, Takahashi T, Kanda T, Morimoto S: Silent information regulator, Sirtuin 1, and age-related diseases. Geriatr & Gerontol Int 2009, 9:7-15.
-
(2009)
Geriatr & Gerontol Int
, vol.9
, pp. 7-15
-
-
Zeng, L.1
Chen, R.2
Liang, F.3
Tsuchiya, H.4
Murai, H.5
Nakahashi, T.6
Iwai, K.7
Takahashi, T.8
Kanda, T.9
Morimoto, S.10
-
6
-
-
85027953113
-
Increased apoptotic chondrocytes in articular cartilage from adult heterozygous SirT1 mice
-
Gabay O, Oppenhiemer H, Meir H, Zaal K, Sanchez C, Dvir-Ginzberg M: Increased apoptotic chondrocytes in articular cartilage from adult heterozygous SirT1 mice. Ann Rheum Dis 2012, 71: 613-616.
-
(2012)
Ann Rheum Dis
, vol.71
, pp. 613-616
-
-
Gabay, O.1
Oppenhiemer, H.2
Meir, H.3
Zaal, K.4
Sanchez, C.5
Dvir-Ginzberg, M.6
-
7
-
-
69449107308
-
SIRT1 regulation of apoptosis of human chondrocytes
-
Takayama K, Ishida K, Matsushita T, Fujita N, Hayashi S, Sasaki K, Tei K, Kubo S, Matsumoto T, Fujioka H, Kurosaka M, Kuroda R: SIRT1 regulation of apoptosis of human chondrocytes. Arthritis Rheum 2009, 60:2731-2740.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 2731-2740
-
-
Takayama, K.1
Ishida, K.2
Matsushita, T.3
Fujita, N.4
Hayashi, S.5
Sasaki, K.6
Tei, K.7
Kubo, S.8
Matsumoto, T.9
Fujioka, H.10
Kurosaka, M.11
Kuroda, R.12
-
8
-
-
77951717549
-
SirT1 enhances survival of human osteoarthritic chondrocytes by repressing protein tyrosine phosphatase 1B and activating the insulin-like growth factor receptor pathway
-
Gagarina V, Gabay O, Dvir-Ginzberg M, Lee EJ, Brady JK, Quon MJ, Hall DJ: SirT1 enhances survival of human osteoarthritic chondrocytes by repressing protein tyrosine phosphatase 1B and activating the insulin-like growth factor receptor pathway. Arthritis Rheum 2010, 62:1383-1392.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 1383-1392
-
-
Gagarina, V.1
Gabay, O.2
Dvir-Ginzberg, M.3
Lee, E.J.4
Brady, J.K.5
Quon, M.J.6
Hall, D.J.7
-
9
-
-
78650978303
-
Potential involvement of SIRT1 in the pathogenesis of osteoarthritis through the modulation of chondrocyte gene expressions
-
Fujita N, Matsushita T, Ishida K, Kubo S, Matsumoto T, Takayama K, Kurosaka M, Kuroda R: Potential involvement of SIRT1 in the pathogenesis of osteoarthritis through the modulation of chondrocyte gene expressions. J Orthop Res 2011, 29:511-515.
-
(2011)
J Orthop Res
, vol.29
, pp. 511-515
-
-
Fujita, N.1
Matsushita, T.2
Ishida, K.3
Kubo, S.4
Matsumoto, T.5
Takayama, K.6
Kurosaka, M.7
Kuroda, R.8
-
10
-
-
79961125549
-
Tumor necrosis factor alpha-mediated cleavage and inactivation of SirT1 in human osteoarthritic chondrocytes
-
Dvir-Ginzberg M, Gagarina V, Lee EJ, Booth R, Gabay O, Hall DJ: Tumor necrosis factor alpha-mediated cleavage and inactivation of SirT1 in human osteoarthritic chondrocytes. Arthritis Rheum 2011, 63:2363-2373.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 2363-2373
-
-
Dvir-Ginzberg, M.1
Gagarina, V.2
Lee, E.J.3
Booth, R.4
Gabay, O.5
Hall, D.J.6
-
11
-
-
84867702707
-
Sirtuin activators and inhibitors
-
Villalba JM, Alcain FJ: Sirtuin activators and inhibitors. Biofactors 2012, 38:349-359.
-
(2012)
Biofactors
, vol.38
, pp. 349-359
-
-
Villalba, J.M.1
Alcain, F.J.2
-
12
-
-
84855559736
-
Resveratrol inhibits interleukin 1β-mediated inducible nitric oxide synthase expression in articular chondrocytes by activating SIRT1 and thereby suppressing nuclear factor-κB activity
-
Lei M, Wang JG, Xiao DM, Fan M, Wang DP, Xiong JY, Chen Y, Ding Y, Liu SL: Resveratrol inhibits interleukin 1β-mediated inducible nitric oxide synthase expression in articular chondrocytes by activating SIRT1 and thereby suppressing nuclear factor-κB activity. Eur J Pharmacol 2012, 674:73-79.
-
(2012)
Eur J Pharmacol
, vol.674
, pp. 73-79
-
-
Lei, M.1
Wang, J.G.2
Xiao, D.M.3
Fan, M.4
Wang, D.P.5
Xiong, J.Y.6
Chen, Y.7
Ding, Y.8
Liu, S.L.9
-
13
-
-
84863880436
-
Effect of resveratrol on cartilage protection and apoptosis inhibition in experimental osteoarthritis of rabbit
-
Wang J, Gao JS, Chen JW, Li F, Tian J: Effect of resveratrol on cartilage protection and apoptosis inhibition in experimental osteoarthritis of rabbit. Rheumatol Int 2012, 32:1541-1548.
-
(2012)
Rheumatol Int
, vol.32
, pp. 1541-1548
-
-
Wang, J.1
Gao, J.S.2
Chen, J.W.3
Li, F.4
Tian, J.5
-
14
-
-
67650091375
-
Resveratrol induces mitochondrial biogenesis in endothelial cells
-
Csiszar A, Labinskyy N, Pinto JT, Ballabh P, Zhang H, Losonczy G, Pearson K, de Cabo R, Zhang C, Ungvari Z: Resveratrol induces mitochondrial biogenesis in endothelial cells. Am J Physiol Heart Circ Physiol 2009, 297:H13-H20.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
-
-
Csiszar, A.1
Labinskyy, N.2
Pinto, J.T.3
Ballabh, P.4
Zhang, H.5
Losonczy, G.6
Pearson, K.7
De Cabo, R.8
Zhang, C.9
Ungvari, Z.10
-
15
-
-
80055113353
-
Activation of Sirt1 by resveratrol inhibits TNF-α induced inflammation in fibroblasts
-
Zhu X, Liu Q, Wang M, Liang M, Yang X, Xu X, Zou H, Qiu J: Activation of Sirt1 by resveratrol inhibits TNF-α induced inflammation in fibroblasts. PLoS One 2011, 6:e27081.
-
(2011)
PLoS One
, vol.6
-
-
Zhu, X.1
Liu, Q.2
Wang, M.3
Liang, M.4
Yang, X.5
Xu, X.6
Zou, H.7
Qiu, J.8
-
17
-
-
3242719545
-
Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase
-
DOI 10.1038/sj.emboj.7600244
-
Yeung F, Hoberg JE, Ramsey CS, Keller MD, Jones DR, Frye RA, Mayo MW: Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J 2004, 23:2369-2380. (Pubitemid 38954844)
-
(2004)
EMBO Journal
, vol.23
, Issue.12
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
Keller, M.D.4
Jones, D.R.5
Frye, R.A.6
Mayo, M.W.7
-
18
-
-
0034802887
-
The p65 (RelA) subunit of NF-κB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression
-
DOI 10.1128/MCB.21.20.7065-7077.2001
-
Ashburner BP, Westerheide SD, Baldwin AS Jr: The p65 (RelA) subunit of NF-κB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. Mol Cell Biol 2001, 21:7065-7077. (Pubitemid 32916079)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.20
, pp. 7065-7077
-
-
Ashburner, B.P.1
Westerheide, S.D.2
Baldwin Jr., A.S.3
-
19
-
-
34548590952
-
Interleukin-6 and cyclic AMP stimulate release of cathepsin B in human osteoblasts
-
Chae HJ, Ha KC, Lee GY, Yang SK, Yun KJ, Kim EC, Kim SH, Chae SW, Kim HR: Interleukin-6 and cyclic AMP stimulate release of cathepsin B in human osteoblasts. Immunopharmacol Immunotoxicol 2007, 29:155-172.
-
(2007)
Immunopharmacol Immunotoxicol
, vol.29
, pp. 155-172
-
-
Chae, H.J.1
Ha, K.C.2
Lee, G.Y.3
Yang, S.K.4
Yun, K.J.5
Kim, E.C.6
Kim, S.H.7
Chae, S.W.8
Kim, H.R.9
-
20
-
-
84871737782
-
Sirtuin 1 enzymatic activity is required for cartilage homeostasis in vivo in a mouse model
-
Gabay O, Sanchez C, Dvir-Ginzberg M, Gagarina V, Zaal KJ, Song Y, He XH, McBurney MW: Sirtuin 1 enzymatic activity is required for cartilage homeostasis in vivo in a mouse model. Arthritis Rheum 2013, 65:159-166.
-
(2013)
Arthritis Rheum
, vol.65
, pp. 159-166
-
-
Gabay, O.1
Sanchez, C.2
Dvir-Ginzberg, M.3
Gagarina, V.4
Zaal, K.J.5
Song, Y.6
He, X.H.7
McBurney, M.W.8
-
21
-
-
84894703144
-
Sirtuin-1 is a nutrient-dependent modulator of inflammation
-
Kotas ME, Gorecki MC, Gillum MP: Sirtuin-1 is a nutrient-dependent modulator of inflammation. Adipocyte 2013, 2:113-118.
-
(2013)
Adipocyte
, vol.2
, pp. 113-118
-
-
Kotas, M.E.1
Gorecki, M.C.2
Gillum, M.P.3
-
22
-
-
50649112638
-
SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase
-
Hou X, Xu S, Maitland-Toolan KA, Sato K, Jiang B, Ido Y, Lan F, Walsh K, Wierzbicki M, Verbeuren TJ, Cohen RA, Zang M: SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase. J Biol Chem 2008, 283:20015-20026.
-
(2008)
J Biol Chem
, vol.283
, pp. 20015-20026
-
-
Hou, X.1
Xu, S.2
Maitland-Toolan, K.A.3
Sato, K.4
Jiang, B.5
Ido, Y.6
Lan, F.7
Walsh, K.8
Wierzbicki, M.9
Verbeuren, T.J.10
Cohen, R.A.11
Zang, M.12
-
23
-
-
84859822652
-
Sirtuin inhibition attenuates the production of inflammatory cytokines in lipopolysaccharide-stimulated macrophages
-
Fernandes CA, Fievez L, Neyrinck AM, Delzenne NM, Bureau F, Vanbever R: Sirtuin inhibition attenuates the production of inflammatory cytokines in lipopolysaccharide-stimulated macrophages. Biochem Biophys Res Commun 2012, 420:857-861.
-
(2012)
Biochem Biophys Res Commun
, vol.420
, pp. 857-861
-
-
Fernandes, C.A.1
Fievez, L.2
Neyrinck, A.M.3
Delzenne, N.M.4
Bureau, F.5
Vanbever, R.6
-
24
-
-
80052453175
-
SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance
-
Niederer F, Ospelt C, Brentano F, Hottiger MO, Gay RE, Gay S, Detmar M, Kyburz D: SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance. Ann Rheum Dis 2011, 70:1866-1873.
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 1866-1873
-
-
Niederer, F.1
Ospelt, C.2
Brentano, F.3
Hottiger, M.O.4
Gay, R.E.5
Gay, S.6
Detmar, M.7
Kyburz, D.8
-
25
-
-
79251554670
-
Histone deacetylase inhibitors impair innate immune response to Toll-like receptor agonists and to infection
-
Roger T, Lugrin J, Le Roy D, Goy G, Mombelli M, Koessler T, Ding XC, Chanson AL, Reymond MK, Miconnet I, Schrenzel J, François P, Calandra T: Histone deacetylase inhibitors impair innate immune response to Toll-like receptor agonists and to infection. Blood 2011, 117:1205-1217.
-
(2011)
Blood
, vol.117
, pp. 1205-1217
-
-
Roger, T.1
Lugrin, J.2
Le Roy, D.3
Goy, G.4
Mombelli, M.5
Koessler, T.6
Ding, X.C.7
Chanson, A.L.8
Reymond, M.K.9
Miconnet, I.10
Schrenzel, J.11
François, P.12
Calandra, T.13
-
26
-
-
80053428068
-
Histone deacetylase inhibitors impair antibacterial defenses of macrophages
-
Mombelli M, Lugrin J, Rubino I, Chanson AL, Giddey M, Calandra T, Roger T: Histone deacetylase inhibitors impair antibacterial defenses of macrophages. J Infect Dis 2011, 204: 1367-1374.
-
(2011)
J Infect Dis
, vol.204
, pp. 1367-1374
-
-
Mombelli, M.1
Lugrin, J.2
Rubino, I.3
Chanson, A.L.4
Giddey, M.5
Calandra, T.6
Roger, T.7
-
27
-
-
63349108526
-
Anti-inflammatory mechanisms of resveratrol in activated HMC-1 cells: Pivotal roles of NF-κB and MAPK
-
Kang OH, Jang HJ, Chae HS, Oh YC, Choi JG, Lee YS, Kim JH, Kim YC, Sohn DH, Park H, Kwon DY: Anti-inflammatory mechanisms of resveratrol in activated HMC-1 cells: pivotal roles of NF-κB and MAPK. Pharmacol Res 2009, 59:330-337.
-
(2009)
Pharmacol Res
, vol.59
, pp. 330-337
-
-
Kang, O.H.1
Jang, H.J.2
Chae, H.S.3
Oh, Y.C.4
Choi, J.G.5
Lee, Y.S.6
Kim, J.H.7
Kim, Y.C.8
Sohn, D.H.9
Park, H.10
Kwon, D.Y.11
-
28
-
-
84878796452
-
Towards elucidating the role of Sirt1 in osteoarthritis
-
Dvir-Ginzberg M, Steinmeyer J: Towards elucidating the role of Sirt1 in osteoarthritis. Front Biosci 2013, 18:343-355.
-
(2013)
Front Biosci
, vol.18
, pp. 343-355
-
-
Dvir-Ginzberg, M.1
Steinmeyer, J.2
|