SIRT1 over-expression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance
Niederer F., Ospelt C., Brentano F., et al. SIRT1 over-expression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance. Ann Rheum Dis 2011, 70:1866-1873.
Resveratrol, a sirtuin 1 activator, increases IL-6 production by peripheral blood mononuclear cells of patients with knee osteoarthritis
Wendling D., Abbas W., Godfrin-Valnet M., et al. Resveratrol, a sirtuin 1 activator, increases IL-6 production by peripheral blood mononuclear cells of patients with knee osteoarthritis. Clin Epigenetics 2013, 5:10. 10.1186/1868-7083-5-10.
Histone deacetylases are dysregulated in rheumatoid arthritis and a novel histone deacetylase 3-selective inhibitor reduces interleukin-6 production by peripheral blood mononuclear cells from rheumatoid arthritis patients
Gillespie J., Savic S., Wong C., et al. Histone deacetylases are dysregulated in rheumatoid arthritis and a novel histone deacetylase 3-selective inhibitor reduces interleukin-6 production by peripheral blood mononuclear cells from rheumatoid arthritis patients. Arthritis Rheum 2012, 64:418-422.
Sirt1 and osteoarthritis. Comments on the paper by Gabay et al.: "Sirt1-deficient mice exhibit an altered cartilage phenotype". Joint Bone Spine 2013
Wendling D., Herbein G. Sirt1 and osteoarthritis. Comments on the paper by Gabay et al.: "Sirt1-deficient mice exhibit an altered cartilage phenotype". Joint Bone Spine 2013. Joint Bone Spine 2014, 81:104-105.