-
1
-
-
34247523141
-
Discovery and biology of IL-23 and IL-27: Related but functionally distinct regulators of inflammation
-
Kastelein RA, Hunter CA, Cua DJ (2007) Discovery and biology of IL-23 and IL-27: Related but functionally distinct regulators of inflammation. Annu Rev Immunol 25: 221-242.
-
(2007)
Annu Rev Immunol
, vol.25
, pp. 221-242
-
-
Kastelein, R.A.1
Hunter, C.A.2
Cua, D.J.3
-
2
-
-
0033638507
-
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
-
Oppmann B, et al. (2000) Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 13: 715-725.
-
(2000)
Immunity
, vol.13
, pp. 715-725
-
-
Oppmann, B.1
-
3
-
-
21844444831
-
New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions
-
Hunter CA (2005) New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions. Nat Rev Immunol 5:521-531.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 521-531
-
-
Hunter, C.A.1
-
4
-
-
2942720565
-
Commensal Gram-negative bacteria prime human dendritic cells for enhanced IL-23 and IL-27 expression and enhanced Th1 development
-
Smits HH, et al. (2004) Commensal Gram-negative bacteria prime human dendritic cells for enhanced IL-23 and IL-27 expression and enhanced Th1 development. Eur J Immunol 34:1371-1380.
-
(2004)
Eur J Immunol
, vol.34
, pp. 1371-1380
-
-
Smits, H.H.1
-
5
-
-
9444244401
-
Prostaglandin E2 induces IL-23 production in bone marrow-derived dendritic cells
-
DOI 10.1096/fj.03-1367fje
-
Sheibanie AF, Tadmori I, Jing H, Vassiliou E, Ganea D (2004) Prostaglandin E2 induces IL-23 production in bone marrow-derived dendritic cells. FASEB J 18:1318-1320. (Pubitemid 39561589)
-
(2004)
FASEB Journal
, vol.18
, Issue.11
, pp. 1318-1320
-
-
Sheibanie, A.F.1
Tadmori, I.2
Jing, H.3
Vassiliou, E.4
Ganea, D.5
-
6
-
-
47949122478
-
In vitro differentiation of dendritic cells in the presence of prostaglandin E2 alters the IL-12/IL-23 balance and promotes differentiation of Th17 cells
-
Khayrullina T, Yen JH, Jing H, Ganea D (2008) In vitro differentiation of dendritic cells in the presence of prostaglandin E2 alters the IL-12/IL-23 balance and promotes differentiation of Th17 cells. J Immunol 181:721-735.
-
(2008)
J Immunol
, vol.181
, pp. 721-735
-
-
Khayrullina, T.1
Yen, J.H.2
Jing, H.3
Ganea, D.4
-
7
-
-
45149118823
-
Differential regulation of interleukin 12 and interleukin 23 production in human dendritic cells
-
DOI 10.1084/jem.20071450
-
Gerosa F, et al. (2008) Differential regulation of interleukin 12 and interleukin 23 production in human dendritic cells. J Exp Med 205:1447-1461. (Pubitemid 351831499)
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.6
, pp. 1447-1461
-
-
Gerosa, F.1
Baldani-Guerra, B.2
Lyakh, L.A.3
Batoni, G.4
Esin, S.5
Winkler-Pickett, R.T.6
Consolaro, M.R.7
De Marchi, M.8
Giachino, D.9
Robbiano, A.10
Astegiano, M.11
Sambataro, A.12
Kastelein, R.A.13
Carra, G.14
Trinchieri, G.15
-
8
-
-
36049033394
-
Signaling to NF-kappaB by Toll-like receptors
-
Kawai T, Akira S (2007) Signaling to NF-kappaB by Toll-like receptors. Trends Mol Med 13:460-469.
-
(2007)
Trends Mol Med
, vol.13
, pp. 460-469
-
-
Kawai, T.1
Akira, S.2
-
9
-
-
39049183044
-
Regulation and function of IKK and IKK-related kinases
-
Häcker H, Karin M (2006) Regulation and function of IKK and IKK-related kinases. Sci STKE 2006:re13.
-
(2006)
Sci STKE 2006:re13
-
-
Häcker, H.1
Karin, M.2
-
10
-
-
33750467991
-
Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models
-
DOI 10.1038/sj.onc.1209944, PII 1209944
-
Gerondakis S, et al. (2006) Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models. Oncogene 25:6781-6799. (Pubitemid 44657852)
-
(2006)
Oncogene
, vol.25
, Issue.51
, pp. 6781-6799
-
-
Gerondakis, S.1
Grumont, R.2
Gugasyan, R.3
Wong, L.4
Isomura, I.5
Ho, W.6
Banerjee, A.7
-
11
-
-
38849199203
-
Shared principles in NF-kappaB signaling
-
Hayden MS, Ghosh S (2008) Shared principles in NF-kappaB signaling. Cell 132: 344-362.
-
(2008)
Cell
, vol.132
, pp. 344-362
-
-
Hayden, M.S.1
Ghosh, S.2
-
12
-
-
42449146639
-
Tumor suppressor CYLD: Negative regulation of NF-kappaB signaling and more
-
Courtois G (2008) Tumor suppressor CYLD: Negative regulation of NF-kappaB signaling and more. Cell Mol Life Sci 65:1123-1132.
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 1123-1132
-
-
Courtois, G.1
-
13
-
-
0041967054
-
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination
-
DOI 10.1038/nature01802
-
Kovalenko A, et al. (2003) The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination. Nature 424:801-805. (Pubitemid 37021712)
-
(2003)
Nature
, vol.424
, Issue.6950
, pp. 801-805
-
-
Kovalenko, A.1
Chable-Bessia, C.2
Cantarella, G.3
Israel, A.4
Wallach, D.5
Courtois, G.6
-
14
-
-
0024397415
-
The structure and regulation of protein phosphatases
-
Cohen P (1989) The structure and regulation of protein phosphatases. Annu Rev Biochem 58:453-508.
-
(1989)
Annu Rev Biochem
, vol.58
, pp. 453-508
-
-
Cohen, P.1
-
15
-
-
27744553677
-
Positive regulation of IkappaB kinase signaling by protein serine/threonine phosphatase 2A
-
DOI 10.1074/jbc.M506093200
-
Kray AE, et al. (2005) Positive regulation of IkappaB kinase signaling by protein serine/threonine phosphatase 2A. J Biol Chem 280:35974-35982. (Pubitemid 41633866)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.43
, pp. 35974-35982
-
-
Kray, A.E.1
Carter, R.S.2
Pennington, K.N.3
Gomez, R.J.4
Sanders, L.E.5
Llanes, J.M.6
Khan, W.N.7
Ballard, D.W.8
Wadzinski, B.E.9
-
16
-
-
37349111560
-
RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling
-
DOI 10.1016/j.molcel.2006.10.015
-
Li S, Wang L, Berman MA, Zhang Y, Dorf ME (2006) RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling. Mol Cell 24:497-509. (Pubitemid 350284222)
-
(2006)
Molecular Cell
, vol.24
, Issue.4
, pp. 497-509
-
-
Li, S.1
Wang, L.2
Berman, M.A.3
Zhang, Y.4
Dorf, M.E.5
-
17
-
-
0032514680
-
Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Calpha
-
DOI 10.1073/pnas.95.21.12370
-
Götz J, Probst A, Ehler E, Hemmings B, Kues W (1998) Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Calpha. Proc Natl Acad Sci USA 95:12370-12375. (Pubitemid 28483772)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.21
, pp. 12370-12375
-
-
Gotz, J.1
Probst, A.2
Ehler, E.3
Hemmings, B.4
Kues, W.5
-
18
-
-
77952377269
-
Negative regulation of MyD88-dependent signaling by IL-10 in dendritic cells
-
Chang J, Kunkel SL, Chang CH (2009) Negative regulation of MyD88-dependent signaling by IL-10 in dendritic cells. Proc Natl Acad Sci USA 106:18327-18332.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 18327-18332
-
-
Chang, J.1
Kunkel, S.L.2
Chang, Ch.3
-
19
-
-
31344442772
-
MAP kinase phosphatase 1 controls innate immune responses and suppresses endotoxic shock
-
DOI 10.1084/jem.20051794
-
Zhao Q, et al. (2006) MAP kinase phosphatase 1 controls innate immune responses and suppresses endotoxic shock. J Exp Med 203:131-140. (Pubitemid 43139652)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.1
, pp. 131-140
-
-
Zhao, Q.1
Wang, X.2
Nelin, L.D.3
Yao, Y.4
Matta, R.5
Manson, M.E.6
Baliga, R.S.7
Meng, X.8
Smith, C.V.9
Bauer, J.A.10
Chang, C.-H.11
Liu, Y.12
-
20
-
-
0030610362
-
A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB
-
DOI 10.1038/41493
-
DiDonato JA, Hayakawa M, Rothwarf DM, Zandi E, Karin M (1997) A cytokineresponsive IkappaB kinase that activates the transcription factor NF-kappaB. Nature 388:548-554. (Pubitemid 27339997)
-
(1997)
Nature
, vol.388
, Issue.6642
, pp. 548-554
-
-
Didonato, J.A.1
Hayakawa, M.2
Rothwarf, D.M.3
Zandi, E.4
Karin, M.5
-
21
-
-
32244442562
-
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
-
DOI 10.1016/j.immuni.2006.01.001, PII S1074761306000045
-
Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B (2006) TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 24:179-189. (Pubitemid 43214587)
-
(2006)
Immunity
, vol.24
, Issue.2
, pp. 179-189
-
-
Veldhoen, M.1
Hocking, R.J.2
Atkins, C.J.3
Locksley, R.M.4
Stockinger, B.5
-
22
-
-
0030804330
-
Inhibition of the Ser-Thr phosphatases PP1 and PP2A by naturally occurring toxins
-
Sheppeck JE, 2nd, Gauss CM, Chamberlin AR (1997) Inhibition of the Ser-Thr phosphatases PP1 and PP2A by naturally occurring toxins. Bioorg Med Chem 5: 1739-1750.
-
(1997)
Bioorg Med Chem
, vol.5
, pp. 1739-1750
-
-
Sheppeck II, J.E.1
Gauss, C.M.2
Chamberlin, A.R.3
-
23
-
-
0023691731
-
Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics
-
Bialojan C, Takai A (1988) Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics. Biochem J 256:283-290.
-
(1988)
Biochem J
, vol.256
, pp. 283-290
-
-
Bialojan, C.1
Takai, A.2
-
24
-
-
0345826130
-
Protein Phosphatase 2Cbeta Association with the IkappaB Kinase Complex is Involved in Regulating NF-kappaB Activity
-
DOI 10.1074/jbc.M306273200
-
Prajapati S, Verma U, Yamamoto Y, Kwak YT, Gaynor RB (2004) Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity. J Biol Chem 279:1739-1746. (Pubitemid 38084441)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.3
, pp. 1739-1746
-
-
Prajapati, S.1
Verma, U.2
Yamamoto, Y.3
Kwak, Y.T.4
Gaynor, R.B.5
-
25
-
-
30444456370
-
IkappaBNS inhibits induction of a subset of toll-like receptor-dependent genes and limits inflammation
-
DOI 10.1016/j.immuni.2005.11.004, PII S1074761305003778
-
Kuwata H, et al. (2006) IkappaBNS inhibits induction of a subset of Toll-like receptordependent genes and limits inflammation. Immunity 24:41-51. (Pubitemid 43077199)
-
(2006)
Immunity
, vol.24
, Issue.1
, pp. 41-51
-
-
Kuwata, H.1
Matsumoto, M.2
Atarashi, K.3
Morishita, H.4
Hirotani, T.5
Koga, R.6
Takeda, K.7
-
26
-
-
42049105550
-
AIP1 recruits phosphatase PP2A to ASK1 in tumor necrosis factor-induced ASK1-JNK activation
-
DOI 10.1161/CIRCRESAHA.107.168153
-
Min W, et al. (2008) AIP1 recruits phosphatase PP2A to ASK1 in tumor necrosis factorinduced ASK1-JNK activation. Circ Res 102:840-848. (Pubitemid 351521590)
-
(2008)
Circulation Research
, vol.102
, Issue.7
, pp. 840-848
-
-
Min, W.1
Lin, Y.2
Tang, S.3
Yu, L.4
Zhang, H.5
Wan, T.6
Luhn, T.7
Fu, H.8
Chen, H.9
-
27
-
-
2642530239
-
An inactive protein phosphatase 2A population is associated with methylesterase and can be re-activated by the phosphotyrosyl phosphatase activator
-
DOI 10.1042/BJ20031643
-
Longin S, et al. (2004) An inactive protein phosphatase 2A population is associated with methylesterase and can be re-activated by the phosphotyrosyl phosphatase activator. Biochem J 380:111-119. (Pubitemid 38725735)
-
(2004)
Biochemical Journal
, vol.380
, Issue.1
, pp. 111-119
-
-
Longin, S.1
Jordens, J.2
Martens, E.3
Stevens, I.4
Janssens, V.5
Rondelez, E.6
De Baere, I.7
Derua, R.8
Waelkens, E.9
Goris, J.10
Van Hoof, C.11
-
28
-
-
33750282677
-
17 axis: Therapeutic targets for autoimmune inflammation
-
DOI 10.1016/j.coi.2006.09.008, PII S0952791506001932
-
Kikly K, Liu L, Na S, Sedgwick JD (2006) The IL-23/Th(17) axis: Therapeutic targets for autoimmune inflammation. Curr Opin Immunol 18:670-675. (Pubitemid 44635178)
-
(2006)
Current Opinion in Immunology
, vol.18
, Issue.6
, pp. 670-675
-
-
Kikly, K.1
Liu, L.2
Na, S.3
Sedgwick, J.D.4
-
29
-
-
0347285359
-
Increased Expression of Interleukin 23 p19 and p40 in Lesional Skin of Patients with Psoriasis Vulgaris
-
DOI 10.1084/jem.20030451
-
Lee E, et al. (2004) Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris. J Exp Med 199:125-130. (Pubitemid 38076484)
-
(2004)
Journal of Experimental Medicine
, vol.199
, Issue.1
, pp. 125-130
-
-
Lee, E.1
Trepicchio, W.L.2
Oestreicher, J.L.3
Pittman, D.4
Wang, F.5
Chamian, F.6
Dhodapkar, M.7
Krueger, J.G.8
-
30
-
-
13944281011
-
Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease: Elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis
-
DOI 10.1097/00054725-200501000-00003
-
Schmidt C, et al. (2005) Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease: Elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis. Inflamm Bowel Dis 11:16-23. (Pubitemid 40340252)
-
(2005)
Inflammatory Bowel Diseases
, vol.11
, Issue.1
, pp. 16-23
-
-
Schmidt, C.1
Giese, T.2
Ludwig, B.3
Mueller-Molaian, I.4
Marth, T.5
Zeuzem, S.6
Meuer, S.C.7
Stallmach, A.8
-
31
-
-
33744936550
-
IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production
-
Vaknin-Dembinsky A, Balashov K, Weiner HL (2006) IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production. J Immunol 176:7768-7774. (Pubitemid 43849078)
-
(2006)
Journal of Immunology
, vol.176
, Issue.12
, pp. 7768-7774
-
-
Vaknin-Dembinsky, A.1
Balashov, K.2
Weiner, H.L.3
-
32
-
-
33750598021
-
Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice
-
DOI 10.1172/JCI28746
-
Zhang J, et al. (2006) Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice. J Clin Invest 116:3042-3049. (Pubitemid 44684489)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.11
, pp. 3042-3049
-
-
Zhang, J.1
Stirling, B.2
Temmerman, S.T.3
Ma, C.A.4
Fuss, I.J.5
Derry, J.M.J.6
Jain, A.7
-
33
-
-
22344444092
-
Interleukin (IL)-4 inhibits IL-10 to promote IL-12 production by dendritic cells
-
DOI 10.1084/jem.20050324
-
Yao Y, Li W, Kaplan MH, Chang CH (2005) Interleukin (IL)-4 inhibits IL-10 to promote IL-12 production by dendritic cells. J Exp Med 201:1899-1903. (Pubitemid 41002926)
-
(2005)
Journal of Experimental Medicine
, vol.201
, Issue.12
, pp. 1899-1903
-
-
Yao, Y.1
Li, W.2
Kaplan, M.H.3
Chang, C.-H.4
|