메뉴 건너뛰기




Volumn 29, Issue 2, 2007, Pages 155-172

Interleukin-6 and cyclic AMP stimulate release of cathepsin B in human osteoblasts

Author keywords

cAMP; Cathepsin B; IL 6; MAPK; Osteoblast; uPA

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CATHEPSIN B; CYCLIC AMP; CYTOKINE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE P38; PYRROLIDINE DITHIOCARBAMATE; SN 50; UROKINASE;

EID: 34548590952     PISSN: 08923973     EISSN: 15322513     Source Type: Journal    
DOI: 10.1080/08923970701511579     Document Type: Article
Times cited : (14)

References (35)
  • 1
    • 0037673933 scopus 로고    scopus 로고
    • Control of osteoblast function and regulation of bone mass
    • Harada, S.; Rodan, G.A. Control of osteoblast function and regulation of bone mass. Nature 2003, 423, 349-355.
    • (2003) Nature , vol.423 , pp. 349-355
    • Harada, S.1    Rodan, G.A.2
  • 2
    • 0037673945 scopus 로고    scopus 로고
    • Osteoclast differentiation and activation
    • Boyle, W.J.; Simonet, W.S.; Lacey, D.L. Osteoclast differentiation and activation. Nature. 2003, 423, 337-342.
    • (2003) Nature , vol.423 , pp. 337-342
    • Boyle, W.J.1    Simonet, W.S.2    Lacey, D.L.3
  • 4
    • 0032540319 scopus 로고    scopus 로고
    • Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
    • Lacey, D.L.; Timms, E.; Tan, H.L.; Kelley, M.J.; Dunstan, C.R.; et al. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 1998, 93, 165-176.
    • (1998) Cell , vol.93 , pp. 165-176
    • Lacey, D.L.1    Timms, E.2    Tan, H.L.3    Kelley, M.J.4    Dunstan, C.R.5
  • 5
    • 0033940651 scopus 로고    scopus 로고
    • Distinct roles of cathepsin K and cathepsin L in osteoclastic bone resorption
    • Furuyama, N.; Fujisawa, Y. Distinct roles of cathepsin K and cathepsin L in osteoclastic bone resorption. Endocr. Res. 2000, 26, 189-204.
    • (2000) Endocr. Res , vol.26 , pp. 189-204
    • Furuyama, N.1    Fujisawa, Y.2
  • 7
    • 12644251053 scopus 로고    scopus 로고
    • E64d, a membrane-permeable cysteine protease inhibitor, attenuates the effects of parathyroid hormone on osteoblasts in vitro
    • Murray, E.J.; Grisanti, M.S.; Bentley, G.V.; Murray, S.S. E64d, a membrane-permeable cysteine protease inhibitor, attenuates the effects of parathyroid hormone on osteoblasts in vitro. Metabolism. 1997, 46, 1090-1094.
    • (1997) Metabolism , vol.46 , pp. 1090-1094
    • Murray, E.J.1    Grisanti, M.S.2    Bentley, G.V.3    Murray, S.S.4
  • 8
    • 0032981308 scopus 로고    scopus 로고
    • Pathogenesis of joint damage in rheumatoid arthritis
    • Bresnihan, B. Pathogenesis of joint damage in rheumatoid arthritis. J Rheumatol. 1999, 26, 717-719.
    • (1999) J Rheumatol , vol.26 , pp. 717-719
    • Bresnihan, B.1
  • 9
    • 0027015335 scopus 로고
    • Physiological mechanisms for metalloproteinase activation
    • Murphy, G.; Ward, R.; Gavrilovic, J.; Atkinson, S. Physiological mechanisms for metalloproteinase activation. Matrix. (suppl) 1992, 1, 224-230.
    • (1992) Matrix. (suppl , vol.1 , pp. 224-230
    • Murphy, G.1    Ward, R.2    Gavrilovic, J.3    Atkinson, S.4
  • 10
    • 0027438713 scopus 로고
    • Inhibition of cartilage proteoglycan release by a specific inactivator of cathepsin B and an inhibitor of matrix metalloproteinases. Evidence for two converging pathways of chondrocyte-mediated proteoglycan degradation
    • Buttle, D.J.; Handley, C.J.; Ilic, M.Z.; Saklatvala, J.; Murata, M.; Barrett, A.J. Inhibition of cartilage proteoglycan release by a specific inactivator of cathepsin B and an inhibitor of matrix metalloproteinases. Evidence for two converging pathways of chondrocyte-mediated proteoglycan degradation. Arthr. Rheum. 1993, 36, 1709-1717.
    • (1993) Arthr. Rheum , vol.36 , pp. 1709-1717
    • Buttle, D.J.1    Handley, C.J.2    Ilic, M.Z.3    Saklatvala, J.4    Murata, M.5    Barrett, A.J.6
  • 11
    • 0032211766 scopus 로고    scopus 로고
    • Cathepsin B: An alternative protease for the generation of an aggrecan 'metalloproteinase' cleavage neoepitope
    • Mort, J.S.; Magny, M.C.; Lee, E.R. Cathepsin B: an alternative protease for the generation of an aggrecan 'metalloproteinase' cleavage neoepitope. Biochem. J. 1998, 335, 491-494.
    • (1998) Biochem. J , vol.335 , pp. 491-494
    • Mort, J.S.1    Magny, M.C.2    Lee, E.R.3
  • 12
    • 0022142088 scopus 로고    scopus 로고
    • Codorean, E.; Gabrielescu, E. Cytochemical investigation of cathepsin B in rheumatoid synovial membrane and fluid. Morphol. Embryol. (Bucur). 1985, 31, 269-274.
    • Codorean, E.; Gabrielescu, E. Cytochemical investigation of cathepsin B in rheumatoid synovial membrane and fluid. Morphol. Embryol. (Bucur). 1985, 31, 269-274.
  • 13
    • 0030837038 scopus 로고    scopus 로고
    • Selective induction of the secretion of cathepsins B and L by cytokines in synovial fibroblast-like cells
    • Lemaire, R.; Huet, G.; Zerimech, F.; Grard, G.; Fontaine, C.; Duquesnoy, B.; Flipo, Selective induction of the secretion of cathepsins B and L by cytokines in synovial fibroblast-like cells. Br. J. Rheumatol. 1997, 36, 735-743.
    • (1997) Br. J. Rheumatol , vol.36 , pp. 735-743
    • Lemaire, R.1    Huet, G.2    Zerimech, F.3    Grard, G.4    Fontaine, C.5    Duquesnoy, B.6    Flipo7
  • 14
    • 0025987727 scopus 로고
    • Cathepsin B in synovial cells at the site of joint destruction in rheumatoid arthritis
    • Trabandt, A.; Gay, R.E.; Fassbender, H.G.; Gay, S. Cathepsin B in synovial cells at the site of joint destruction in rheumatoid arthritis. Arthr. Rheum. 1991, 34, 1444-1451.
    • (1991) Arthr. Rheum , vol.34 , pp. 1444-1451
    • Trabandt, A.1    Gay, R.E.2    Fassbender, H.G.3    Gay, S.4
  • 15
    • 0027535914 scopus 로고
    • Biology and biochemistry of proteinases in tumor invasion
    • Mignatti, P.; Rifkin, D.B. Biology and biochemistry of proteinases in tumor invasion. Physiol. Rev. 1993, 73, 161-195.
    • (1993) Physiol. Rev , vol.73 , pp. 161-195
    • Mignatti, P.1    Rifkin, D.B.2
  • 16
    • 0026703365 scopus 로고
    • Plasminogen activator regulation in osteoblasts: Parathyroid hormone inhibition of type-1 plasminogen activator inhibitor and its mRNA
    • Fukumoto, S.; Allan, E.H.; Yee, J.A.; Gelehrter, T.D.; Martin. T.J.; Plasminogen activator regulation in osteoblasts: parathyroid hormone inhibition of type-1 plasminogen activator inhibitor and its mRNA. J. Cell Physiol. 1992, 152, 346-355.
    • (1992) J. Cell Physiol , vol.152 , pp. 346-355
    • Fukumoto, S.1    Allan, E.H.2    Yee, J.A.3    Gelehrter, T.D.4    Martin, T.J.5
  • 17
    • 0029416956 scopus 로고
    • Prostaglandin E2 regulates production of plasminogen activator isoenzymes, urokinase receptor, and plasminogen activator inhibitor-1 in primary cultures of rat calvarial osteoblasts
    • Allan, E.H.; Martin, T.J. Prostaglandin E2 regulates production of plasminogen activator isoenzymes, urokinase receptor, and plasminogen activator inhibitor-1 in primary cultures of rat calvarial osteoblasts. J. Cell Physiol. 1995, 165, 521-529.
    • (1995) J. Cell Physiol , vol.165 , pp. 521-529
    • Allan, E.H.1    Martin, T.J.2
  • 18
    • 0033054362 scopus 로고    scopus 로고
    • Carmeliet. G.. The role of the plasminogen system in bone resorption in vitro
    • Daci, E.; Udagawa. N.; Martin, T.J.; Bouillon, R.; Carmeliet. G.. The role of the plasminogen system in bone resorption in vitro. J. Bone Miner. Res. 1999, 14, 946-952.
    • (1999) J. Bone Miner. Res , vol.14 , pp. 946-952
    • Daci, E.1    Udagawa, N.2    Martin, T.J.3    Bouillon, R.4
  • 19
    • 0028237332 scopus 로고
    • Relationship of the plasminogen activator/plasmin cascade to osteoclast invasion and mineral resorption in explanted fetal metatarsal bones
    • Leloup G., Delaisse, J.M., Vaes, G. Relationship of the plasminogen activator/plasmin cascade to osteoclast invasion and mineral resorption in explanted fetal metatarsal bones. J. Bone Miner. Res. 1994, 9, 891-902.
    • (1994) J. Bone Miner. Res , vol.9 , pp. 891-902
    • Leloup, G.1    Delaisse, J.M.2    Vaes, G.3
  • 20
    • 0029783970 scopus 로고    scopus 로고
    • Vaes, G.. Bone resorption and response to calcium-regulating hormones in the absence of tissue or urokinase plasminogen activator or of their type 1 inhibitor
    • Leloup, G.; Lemoine. P.; Carmeliet, P.; Vaes, G.. Bone resorption and response to calcium-regulating hormones in the absence of tissue or urokinase plasminogen activator or of their type 1 inhibitor. J. Bone Miner. Res. 1996, 11, 1146-1157.
    • (1996) J. Bone Miner. Res , vol.11 , pp. 1146-1157
    • Leloup, G.1    Lemoine, P.2    Carmeliet, P.3
  • 21
    • 0025253851 scopus 로고
    • Biology of multifunctional cytokines: IL 6 and related molecules (IL 1 and TNF)
    • Akira, S.; Hirano, T.; Taga, T.; Kishimoto, T. Biology of multifunctional cytokines: IL 6 and related molecules (IL 1 and TNF). FASEB J. 1990, 4, 2860-2867.
    • (1990) FASEB J , vol.4 , pp. 2860-2867
    • Akira, S.1    Hirano, T.2    Taga, T.3    Kishimoto, T.4
  • 22
    • 24944439793 scopus 로고    scopus 로고
    • Intestinal inflammation-induced growth retardation acts through IL-6 in rats and depends on the -174 IL-6 G/C polymorphism in children
    • Sawczenko, A.; Azooz, O.; Paraszczuk, J.; Idestrom, M.; Croft, N.M.; et al. Intestinal inflammation-induced growth retardation acts through IL-6 in rats and depends on the -174 IL-6 G/C polymorphism in children. Proc. Natl. Acad. Sci. U S A. 2005, 102, 13260-13265.
    • (2005) Proc. Natl. Acad. Sci. U S A , vol.102 , pp. 13260-13265
    • Sawczenko, A.1    Azooz, O.2    Paraszczuk, J.3    Idestrom, M.4    Croft, N.M.5
  • 23
    • 0028031990 scopus 로고
    • Interleukin-6 (IL-6) as an anti-inflammatory cytokine: Induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55
    • Tilg, H.; Trehu, E.; Atkins, M.B.; Dinarello, C.A.; Mier, J.W. Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55. Blood 1994, 83, 113-118.
    • (1994) Blood , vol.83 , pp. 113-118
    • Tilg, H.1    Trehu, E.2    Atkins, M.B.3    Dinarello, C.A.4    Mier, J.W.5
  • 24
    • 0033032092 scopus 로고    scopus 로고
    • Transcriptional regulation of the interleukin-6 gene in mesangial cells
    • Grassl, C.; Luckow, B.; Schlondorff, D.; Dendorfer, U. Transcriptional regulation of the interleukin-6 gene in mesangial cells. J. Am. Soc. Nephrol. 1999, 10, 1466-1477.
    • (1999) J. Am. Soc. Nephrol , vol.10 , pp. 1466-1477
    • Grassl, C.1    Luckow, B.2    Schlondorff, D.3    Dendorfer, U.4
  • 25
    • 33244471726 scopus 로고    scopus 로고
    • Noncanonical cAMP pathway and p38 MAPK mediate beta2-adrenergic receptor-induced IL-6 production in neonatal mouse cardiac fibroblasts
    • Yin, F.; Wang, Y.Y.; Du, J.H.; Li, C.; Lu, Z.Z.; et al. Noncanonical cAMP pathway and p38 MAPK mediate beta2-adrenergic receptor-induced IL-6 production in neonatal mouse cardiac fibroblasts. J. Mol. Cell Cardiol. 2006, 40, 384-393.
    • (2006) J. Mol. Cell Cardiol , vol.40 , pp. 384-393
    • Yin, F.1    Wang, Y.Y.2    Du, J.H.3    Li, C.4    Lu, Z.Z.5
  • 26
    • 10944265518 scopus 로고    scopus 로고
    • Adenylyl cyclase-cAMP system inhibits thyroid hormone-stimulated osteocalcin synthesis in osteoblasts
    • Kanno, Y.; Ishisaki, A.; Yoshida, M.; Nakajima, K.; Tokuda, H.; et al. Adenylyl cyclase-cAMP system inhibits thyroid hormone-stimulated osteocalcin synthesis in osteoblasts. Mol. Cell Endocrinol. 2005, 229, 75-82.
    • (2005) Mol. Cell Endocrinol , vol.229 , pp. 75-82
    • Kanno, Y.1    Ishisaki, A.2    Yoshida, M.3    Nakajima, K.4    Tokuda, H.5
  • 27
    • 0035142048 scopus 로고    scopus 로고
    • The p38 mitogen-activated protein kinase pathway regulates interleukin-6 synthesis in response to tumor necrosis factor in osteoblasts
    • Chae, H.J.; Chae, S.W.; Chin, H.Y.; Bang, B.G.; Cho, S.B.; et al. The p38 mitogen-activated protein kinase pathway regulates interleukin-6 synthesis in response to tumor necrosis factor in osteoblasts. Bone. 2001, 28, 45-53.
    • (2001) Bone , vol.28 , pp. 45-53
    • Chae, H.J.1    Chae, S.W.2    Chin, H.Y.3    Bang, B.G.4    Cho, S.B.5
  • 28
    • 0025865317 scopus 로고
    • The inducible transcription activator NF-kappa B: Regulation by distinct protein subunits
    • Baeuerle, P.A. The inducible transcription activator NF-kappa B: regulation by distinct protein subunits. Biochim. Biophys. Acta. 1991, 1072, 63-80.
    • (1991) Biochim. Biophys. Acta , vol.1072 , pp. 63-80
    • Baeuerle, P.A.1
  • 29
    • 8944222565 scopus 로고    scopus 로고
    • Increased IL-6-production by cells isolated from the fibrous bone dysplasia tissues in patients with McCune-Albright syndrome
    • Yamamoto, T.; Ozono, K.; Kasayama, S.; Yoh, K.; Hiroshima, K.; et al. Increased IL-6-production by cells isolated from the fibrous bone dysplasia tissues in patients with McCune-Albright syndrome. J. Clin. Invest. 1996, 98, 30-35.
    • (1996) J. Clin. Invest , vol.98 , pp. 30-35
    • Yamamoto, T.1    Ozono, K.2    Kasayama, S.3    Yoh, K.4    Hiroshima, K.5
  • 30
    • 0025999255 scopus 로고
    • Tissue and urokinase plasminogen activators in bone tissue and their regulation by parathyroid hormone
    • Leloup, G.; Peeters-Joris, C.; Delaisse, J.M.; Opdenakker, G..; Vaes, G.. Tissue and urokinase plasminogen activators in bone tissue and their regulation by parathyroid hormone. J. Bone Miner. Res. 1991, 6, 1081-1090.
    • (1991) J. Bone Miner. Res , vol.6 , pp. 1081-1090
    • Leloup, G.1    Peeters-Joris, C.2    Delaisse, J.M.3    Opdenakker, G.4    Vaes, G.5
  • 31
    • 0027071850 scopus 로고
    • The effect of transforming growth factor beta on the plasminogen activator activity of normal human osteoblast-like cells and a human osteosarcoma cell line MG-63
    • Fawthrop, F.W.; Oyajobi, B.O.; Bunning, R.A.; Russell, R.G.. The effect of transforming growth factor beta on the plasminogen activator activity of normal human osteoblast-like cells and a human osteosarcoma cell line MG-63. J. Bone Miner. Res. 1992, 7, 1363-1371.
    • (1992) J. Bone Miner. Res , vol.7 , pp. 1363-1371
    • Fawthrop, F.W.1    Oyajobi, B.O.2    Bunning, R.A.3    Russell, R.G.4
  • 32
    • 0029145671 scopus 로고
    • Regulation of plasminogen activation, matrix metalloproteinases and urokinase-type plasminogen activator-mediated extracellular matrix degradation in human osteosarcoma cell line MG63 by interleukin-1 alpha
    • de Bart, A.C.; Quax, P.H.; Lowik, C.W.; Verheijen, J.H. Regulation of plasminogen activation, matrix metalloproteinases and urokinase-type plasminogen activator-mediated extracellular matrix degradation in human osteosarcoma cell line MG63 by interleukin-1 alpha. J. Bone Miner. Res. 1995, 10, 1374-1384.
    • (1995) J. Bone Miner. Res , vol.10 , pp. 1374-1384
    • de Bart, A.C.1    Quax, P.H.2    Lowik, C.W.3    Verheijen, J.H.4
  • 33
    • 0027968219 scopus 로고    scopus 로고
    • Campbell, P.G..; Wines, K.; Yanosick, T.B.; Novak, J.F. Binding and activation of plasminogen on the surface of osteosarcoma cells. J. Cell Physiol. 1994, 159 (1), 1-10.
    • Campbell, P.G..; Wines, K.; Yanosick, T.B.; Novak, J.F. Binding and activation of plasminogen on the surface of osteosarcoma cells. J. Cell Physiol. 1994, 159 (1), 1-10.
  • 34
    • 0026516022 scopus 로고
    • Effective activation of the proenzyme form of the urokinase-type plasminogen activator (pro-uPA) by the cysteine protease cathepsin L
    • Goretzki, L.; Schmitt, M.; Mann, K.; Calvete, J.; Chucholowski, N.; et al. Effective activation of the proenzyme form of the urokinase-type plasminogen activator (pro-uPA) by the cysteine protease cathepsin L. FEBS Lett. 1992, 297, 112-118.
    • (1992) FEBS Lett , vol.297 , pp. 112-118
    • Goretzki, L.1    Schmitt, M.2    Mann, K.3    Calvete, J.4    Chucholowski, N.5
  • 35
    • 0025995714 scopus 로고
    • Biological and clinical relevance of the urokinase-type plasminogen activator (uPA) in breast cancer
    • Schmitt, M.; Goretzki, L.; Janicke, F.; Calvete, J.; Eulitz, M.; et al. Biological and clinical relevance of the urokinase-type plasminogen activator (uPA) in breast cancer. Biomed. Biochim Acta. 1991, 50, 731-741.
    • (1991) Biomed. Biochim Acta , vol.50 , pp. 731-741
    • Schmitt, M.1    Goretzki, L.2    Janicke, F.3    Calvete, J.4    Eulitz, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.