메뉴 건너뛰기




Volumn 91, Issue 3, 2014, Pages 348-358

Analyses on the mechanisms that underlie the chondroprotective properties of calcitonin

Author keywords

[No Author keywords available]

Indexed keywords

5 ACETAMIDO 2 (2 METHOXYETHOXY)ACETOPHENONE; AGGRECANASE 2; CALCITONIN; CASPASE 3; CHONDROPROTECTIVE AGENT; COLLAGEN TYPE 2; COLLAGEN TYPE 2A1; COLLAGENASE 3; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; G PROTEIN COUPLED RECEPTOR; GLYCOSAMINOGLYCAN; INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; PREDNISOLONE; PROTEIN BAX; PROTEIN BCL 2; PROTEOGLYCAN; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; ACAN PROTEIN, HUMAN; ADAM PROTEIN; ADAMTS5 PROTEIN, HUMAN; AGGRECAN; BIOLOGICAL MARKER; COL2A1 PROTEIN, HUMAN; MMP13 PROTEIN, HUMAN; PROTECTIVE AGENT; SOX9 PROTEIN, HUMAN;

EID: 84925707221     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2014.07.034     Document Type: Article
Times cited : (10)

References (69)
  • 1
    • 0031602467 scopus 로고    scopus 로고
    • Articular cartilage: Degeneration and osteoarthritis, repair, regeneration, and transplantation
    • J.A. Buckwalter, and H.J. Mankin Articular cartilage: degeneration and osteoarthritis, repair, regeneration, and transplantation Instr Course Lect 47 1998 487 504
    • (1998) Instr Course Lect , vol.47 , pp. 487-504
    • Buckwalter, J.A.1    Mankin, H.J.2
  • 2
    • 33746682471 scopus 로고    scopus 로고
    • The chondrocyte: Biology and clinical application
    • Z. Lin, C. Willers, J. Xu, and M.H. Zheng The chondrocyte: biology and clinical application Tissue Eng 12 2006 1971 1984
    • (2006) Tissue Eng , vol.12 , pp. 1971-1984
    • Lin, Z.1    Willers, C.2    Xu, J.3    Zheng, M.H.4
  • 4
    • 0038639763 scopus 로고    scopus 로고
    • Aggrecanases and cartilage matrix degradation
    • H. Nagase, and M. Kashiwagi Aggrecanases and cartilage matrix degradation Arthritis Res Ther 5 2003 94 103
    • (2003) Arthritis Res Ther , vol.5 , pp. 94-103
    • Nagase, H.1    Kashiwagi, M.2
  • 5
    • 0026736030 scopus 로고
    • Localization of matrix metalloproteinase 3 (stromelysin) in osteoarthritic cartilage and synovium
    • Y. Okada, M. Shinmei, O. Tanaka, K. Naka, A. Kimura, and I. Nakanishi Localization of matrix metalloproteinase 3 (stromelysin) in osteoarthritic cartilage and synovium Lab Invest 66 1992 680 690
    • (1992) Lab Invest , vol.66 , pp. 680-690
    • Okada, Y.1    Shinmei, M.2    Tanaka, O.3    Naka, K.4    Kimura, A.5    Nakanishi, I.6
  • 7
    • 84893782724 scopus 로고    scopus 로고
    • Homeostatic mechanisms in articular cartilage and role of inflammation in osteoarthritis
    • X. Houard, M.B. Goldring, and F. Berenbaum Homeostatic mechanisms in articular cartilage and role of inflammation in osteoarthritis Curr Rheumatol Rep 15 2013 375
    • (2013) Curr Rheumatol Rep , vol.15 , pp. 375
    • Houard, X.1    Goldring, M.B.2    Berenbaum, F.3
  • 8
    • 0031658981 scopus 로고    scopus 로고
    • Linkage of chondrocyte apoptosis and cartilage degradation in human osteoarthritis
    • S. Hashimoto, R.L. Ochs, S. Komiya, and M. Lotz Linkage of chondrocyte apoptosis and cartilage degradation in human osteoarthritis Arthritis Rheumatol 41 1998 1632 1638
    • (1998) Arthritis Rheumatol , vol.41 , pp. 1632-1638
    • Hashimoto, S.1    Ochs, R.L.2    Komiya, S.3    Lotz, M.4
  • 9
    • 33745044261 scopus 로고    scopus 로고
    • Cytokines, tumor necrosis factor-alpha and interleukin-1beta, differentially regulate apoptosis in osteoarthritis cultured human chondrocytes
    • M.J. Lopez-Armada, B. Carames, M. Lires-Dean, B. Cillero-Pastor, C. Ruiz-Romero, and F. Galdo Cytokines, tumor necrosis factor-alpha and interleukin-1beta, differentially regulate apoptosis in osteoarthritis cultured human chondrocytes Osteoarthr Cartil 14 2006 660 669
    • (2006) Osteoarthr Cartil , vol.14 , pp. 660-669
    • Lopez-Armada, M.J.1    Carames, B.2    Lires-Dean, M.3    Cillero-Pastor, B.4    Ruiz-Romero, C.5    Galdo, F.6
  • 10
    • 49749209764 scopus 로고
    • Further evidence for calcitonin. A rapid-acting hormone which lowers plasma-calcium
    • M.A. Kumar, G.V. Foster, and I. Macintyre Further evidence for calcitonin. A rapid-acting hormone which lowers plasma-calcium Lancet 2 1963 480 482
    • (1963) Lancet , vol.2 , pp. 480-482
    • Kumar, M.A.1    Foster, G.V.2    Macintyre, I.3
  • 11
    • 0020603446 scopus 로고
    • The sensitivity of isolated osteoclasts to morphological transformation by calcitonin
    • T.J. Chambers, and A. Moore The sensitivity of isolated osteoclasts to morphological transformation by calcitonin J Clin Endo Met 57 1983 819 824
    • (1983) J Clin Endo Met , vol.57 , pp. 819-824
    • Chambers, T.J.1    Moore, A.2
  • 12
    • 0036679570 scopus 로고    scopus 로고
    • Meta-analyses of therapies for postmenopausal osteoporosis. VI. Meta-analysis of calcitonin for the treatment of postmenopausal osteoporosis
    • A. Cranney, P. Tugwell, N. Zytaruk, V. Robinson, B. Weaver, and B. Shea Meta-analyses of therapies for postmenopausal osteoporosis. VI. Meta-analysis of calcitonin for the treatment of postmenopausal osteoporosis Endocr Rev 23 2002 540 551
    • (2002) Endocr Rev , vol.23 , pp. 540-551
    • Cranney, A.1    Tugwell, P.2    Zytaruk, N.3    Robinson, V.4    Weaver, B.5    Shea, B.6
  • 13
    • 84880718145 scopus 로고    scopus 로고
    • Paget disease of bone: Diagnosis and drug therapy
    • M. Seton Paget disease of bone: diagnosis and drug therapy Cleveland Clin J Med 80 2013 452 462
    • (2013) Cleveland Clin J Med , vol.80 , pp. 452-462
    • Seton, M.1
  • 14
    • 33745622400 scopus 로고    scopus 로고
    • Calcitonin directly attenuates collagen type II degradation by inhibition of matrix metalloproteinase expression and activity in articular chondrocytes
    • B.C. Sondergaard, H. Wulf, K. Henriksen, S. Schaller, S. Oestergaard, and P. Qvist Calcitonin directly attenuates collagen type II degradation by inhibition of matrix metalloproteinase expression and activity in articular chondrocytes Osteoarthr Cartil 14 2006 759 768
    • (2006) Osteoarthr Cartil , vol.14 , pp. 759-768
    • Sondergaard, B.C.1    Wulf, H.2    Henriksen, K.3    Schaller, S.4    Oestergaard, S.5    Qvist, P.6
  • 16
    • 34547778854 scopus 로고    scopus 로고
    • The effect of oral calcitonin on cartilage turnover and surface erosion in an ovariectomized rat model
    • B.C. Sondergaard, S. Oestergaard, C. Christiansen, L.B. Tanko, and M.A. Karsdal The effect of oral calcitonin on cartilage turnover and surface erosion in an ovariectomized rat model Arthritis Rheumatol 56 2007 2674 2678
    • (2007) Arthritis Rheumatol , vol.56 , pp. 2674-2678
    • Sondergaard, B.C.1    Oestergaard, S.2    Christiansen, C.3    Tanko, L.B.4    Karsdal, M.A.5
  • 17
    • 84884724598 scopus 로고    scopus 로고
    • The potential protective effects of calcitonin involved in coordinating chondrocyte response, extracellular matrix, and subchondral trabecular bone in experimental osteoarthritis
    • T. Cheng, L. Zhang, X. Fu, W. Wang, H. Xu, and H. Song The potential protective effects of calcitonin involved in coordinating chondrocyte response, extracellular matrix, and subchondral trabecular bone in experimental osteoarthritis Connect Tissue Res 54 2013 139 146
    • (2013) Connect Tissue Res , vol.54 , pp. 139-146
    • Cheng, T.1    Zhang, L.2    Fu, X.3    Wang, W.4    Xu, H.5    Song, H.6
  • 18
    • 80555150580 scopus 로고    scopus 로고
    • High density micromass cultures of a human chondrocyte cell line: A reliable assay system to reveal the modulatory functions of pharmacological agents
    • K.V. Greco, A.J. Iqbal, L. Rattazzi, G. Nalesso, N. Moradi-Bidhendi, and A.R. Moore High density micromass cultures of a human chondrocyte cell line: a reliable assay system to reveal the modulatory functions of pharmacological agents Biochem Pharmacol 82 2011 1919 1929
    • (2011) Biochem Pharmacol , vol.82 , pp. 1919-1929
    • Greco, K.V.1    Iqbal, A.J.2    Rattazzi, L.3    Nalesso, G.4    Moradi-Bidhendi, N.5    Moore, A.R.6
  • 20
    • 79956195519 scopus 로고    scopus 로고
    • WNT-3A modulates articular chondrocyte phenotype by activating both canonical and noncanonical pathways
    • G. Nalesso, J. Sherwood, J. Bertrand, T. Pap, M. Ramachandran, and C. De Bari WNT-3A modulates articular chondrocyte phenotype by activating both canonical and noncanonical pathways J Cell Biol 193 2011 551 564
    • (2011) J Cell Biol , vol.193 , pp. 551-564
    • Nalesso, G.1    Sherwood, J.2    Bertrand, J.3    Pap, T.4    Ramachandran, M.5    De Bari, C.6
  • 21
    • 84864652059 scopus 로고    scopus 로고
    • Chondroprotective and anti-inflammatory role of melanocortin peptides in TNF-alpha activated human C-20/A4 chondrocytes
    • M.K. Kaneva, M.J. Kerrigan, P. Grieco, G.P. Curley, I.C. Locke, and S.J. Getting Chondroprotective and anti-inflammatory role of melanocortin peptides in TNF-alpha activated human C-20/A4 chondrocytes Br J Pharmacol 167 2012 67 79
    • (2012) Br J Pharmacol , vol.167 , pp. 67-79
    • Kaneva, M.K.1    Kerrigan, M.J.2    Grieco, P.3    Curley, G.P.4    Locke, I.C.5    Getting, S.J.6
  • 22
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • M.W. Pfaffl A new mathematical model for relative quantification in real-time RT-PCR Nucleic Acids Res 29 2001 e45
    • (2001) Nucleic Acids Res , vol.29 , pp. e45
    • Pfaffl, M.W.1
  • 23
    • 0030899953 scopus 로고    scopus 로고
    • Calcitonin inhibits phospholipase A2 and collagenase activity of human osteoarthritic chondrocytes
    • M.P. Hellio, M.J. Peschard, C. Cohen, M. Richard, and E. Vignon Calcitonin inhibits phospholipase A2 and collagenase activity of human osteoarthritic chondrocytes Osteoarthr Cartil 5 1997 121 128
    • (1997) Osteoarthr Cartil , vol.5 , pp. 121-128
    • Hellio, M.P.1    Peschard, M.J.2    Cohen, C.3    Richard, M.4    Vignon, E.5
  • 24
  • 25
    • 0034945018 scopus 로고    scopus 로고
    • Molecular markers predictive of the capacity of expanded human articular chondrocytes to form stable cartilage in vivo
    • F. Dell'Accio, C. De Bari, and F.P. Luyten Molecular markers predictive of the capacity of expanded human articular chondrocytes to form stable cartilage in vivo Arthritis Rheumatol 44 2001 1608 1619
    • (2001) Arthritis Rheumatol , vol.44 , pp. 1608-1619
    • Dell'Accio, F.1    De Bari, C.2    Luyten, F.P.3
  • 26
    • 0020369710 scopus 로고
    • Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels
    • P.D. Benya, and J.D. Shaffer Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels Cell 30 1982 215 224
    • (1982) Cell , vol.30 , pp. 215-224
    • Benya, P.D.1    Shaffer, J.D.2
  • 27
    • 0019810824 scopus 로고
    • Calcitonin induction of a persistent activated state of adenylate cyclase in human breast cancer cells (T 47D)
    • S.J. Lamp, D.M. Findlay, J.M. Moseley, and T.J. Martin Calcitonin induction of a persistent activated state of adenylate cyclase in human breast cancer cells (T 47D) J Biol Chem 256 1981 12269 12274
    • (1981) J Biol Chem , vol.256 , pp. 12269-12274
    • Lamp, S.J.1    Findlay, D.M.2    Moseley, J.M.3    Martin, T.J.4
  • 28
    • 0017727636 scopus 로고
    • Calcitonin-responsive adenylate cyclase in a calcitonin-producing human cancer cell line
    • N.H. Hunt, M. Ellison, J.C. Underwood, and T.J. Martin Calcitonin-responsive adenylate cyclase in a calcitonin-producing human cancer cell line Br J Cancer 35 1977 777 784
    • (1977) Br J Cancer , vol.35 , pp. 777-784
    • Hunt, N.H.1    Ellison, M.2    Underwood, J.C.3    Martin, T.J.4
  • 29
    • 0026654916 scopus 로고
    • A recombinant calcitonin receptor independently stimulates 3',5'-cyclic adenosine monophosphate and Ca2+/inositol phosphate signaling pathways
    • O. Chabre, B.R. Conklin, H.Y. Lin, H.F. Lodish, E. Wilson, and H.E. Ives A recombinant calcitonin receptor independently stimulates 3',5'-cyclic adenosine monophosphate and Ca2+/inositol phosphate signaling pathways Mol Endocrinol 6 1992 551 556
    • (1992) Mol Endocrinol , vol.6 , pp. 551-556
    • Chabre, O.1    Conklin, B.R.2    Lin, H.Y.3    Lodish, H.F.4    Wilson, E.5    Ives, H.E.6
  • 30
    • 0034458515 scopus 로고    scopus 로고
    • Calcitonin and calcitonin receptors: Bone and beyond
    • M. Pondel Calcitonin and calcitonin receptors: bone and beyond Int J Exp Pathol 81 2000 405 422
    • (2000) Int J Exp Pathol , vol.81 , pp. 405-422
    • Pondel, M.1
  • 31
    • 0025248571 scopus 로고
    • Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells
    • T. Chijiwa, A. Mishima, M. Hagiwara, M. Sano, K. Hayashi, and T. Inoue Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells J Biol Chem 265 1990 5267 5272
    • (1990) J Biol Chem , vol.265 , pp. 5267-5272
    • Chijiwa, T.1    Mishima, A.2    Hagiwara, M.3    Sano, M.4    Hayashi, K.5    Inoue, T.6
  • 32
    • 0017685035 scopus 로고
    • Effects of calcitonin and parathyroid hormone on the metabolism of chondrocytes in culture
    • K. Deshmukh, W.G. Kline, and B.D. Sawyer Effects of calcitonin and parathyroid hormone on the metabolism of chondrocytes in culture Biochim Biophys Acta 499 1977 28 35
    • (1977) Biochim Biophys Acta , vol.499 , pp. 28-35
    • Deshmukh, K.1    Kline, W.G.2    Sawyer, B.D.3
  • 33
    • 34447096652 scopus 로고    scopus 로고
    • Signalling to transcription: Store-operated Ca2+ entry and NFAT activation in lymphocytes
    • Y. Gwack, S. Feske, S. Srikanth, P.G. Hogan, and A. Rao Signalling to transcription: store-operated Ca2+ entry and NFAT activation in lymphocytes Cell Calcium 42 2007 145 156
    • (2007) Cell Calcium , vol.42 , pp. 145-156
    • Gwack, Y.1    Feske, S.2    Srikanth, S.3    Hogan, P.G.4    Rao, A.5
  • 34
    • 34247130944 scopus 로고    scopus 로고
    • Effects of glucocorticoids on inflammation and arthritis
    • E.F. Morand Effects of glucocorticoids on inflammation and arthritis Curr Opin Rheumatol 19 2007 302 307
    • (2007) Curr Opin Rheumatol , vol.19 , pp. 302-307
    • Morand, E.F.1
  • 35
    • 78649749715 scopus 로고    scopus 로고
    • Anti-inflammatory and antiosteoclastogenesis properties of endogenous melanocortin receptor type 3 in experimental arthritis
    • H.B. Patel, M. Bombardieri, A.L. Sampaio, F. D'Acquisto, M. Gray, and P. Grieco Anti-inflammatory and antiosteoclastogenesis properties of endogenous melanocortin receptor type 3 in experimental arthritis FASEB J 24 2010 4835 4843
    • (2010) FASEB J , vol.24 , pp. 4835-4843
    • Patel, H.B.1    Bombardieri, M.2    Sampaio, A.L.3    D'Acquisto, F.4    Gray, M.5    Grieco, P.6
  • 36
    • 0024356023 scopus 로고
    • Effects of human and salmon calcitonin on human articular chondrocytes cultivated in clusters
    • P. Franchimont, C. Bassleer, Y. Henrotin, P. Gysen, and R. Bassleer Effects of human and salmon calcitonin on human articular chondrocytes cultivated in clusters J Clin Endocrinol Met 69 1989 259 266
    • (1989) J Clin Endocrinol Met , vol.69 , pp. 259-266
    • Franchimont, P.1    Bassleer, C.2    Henrotin, Y.3    Gysen, P.4    Bassleer, R.5
  • 37
    • 0033031985 scopus 로고    scopus 로고
    • Treatment with calcitonin suppresses the responses of bone, cartilage, and synovium in the early stages of canine experimental osteoarthritis and significantly reduces the severity of the cartilage lesions
    • D.H. Manicourt, R.D. Altman, J.M. Williams, J.P. Devogelaer, A. Druetz-Van Egeren, and M.E. Lenz Treatment with calcitonin suppresses the responses of bone, cartilage, and synovium in the early stages of canine experimental osteoarthritis and significantly reduces the severity of the cartilage lesions Arthritis Rheumatol 42 1999 1159 1167
    • (1999) Arthritis Rheumatol , vol.42 , pp. 1159-1167
    • Manicourt, D.H.1    Altman, R.D.2    Williams, J.M.3    Devogelaer, J.P.4    Druetz-Van Egeren, A.5    Lenz, M.E.6
  • 38
    • 7744219600 scopus 로고    scopus 로고
    • Treatment with calcitonin prevents the net loss of collagen, hyaluronan and proteoglycan aggregates from cartilage in the early stages of canine experimental osteoarthritis
    • H. El Hajjaji, J.M. Williams, J.P. Devogelaer, M.E. Lenz, E.J. Thonar, and D.H. Manicourt Treatment with calcitonin prevents the net loss of collagen, hyaluronan and proteoglycan aggregates from cartilage in the early stages of canine experimental osteoarthritis Osteoarthr Cartil 12 2004 904 911
    • (2004) Osteoarthr Cartil , vol.12 , pp. 904-911
    • El Hajjaji, H.1    Williams, J.M.2    Devogelaer, J.P.3    Lenz, M.E.4    Thonar, E.J.5    Manicourt, D.H.6
  • 39
    • 16644397861 scopus 로고    scopus 로고
    • Effects of calcitonin on subchondral trabecular bone changes and on osteoarthritic cartilage lesions after acute anterior cruciate ligament deficiency
    • C. Behets, J.M. Williams, D. Chappard, J.P. Devogelaer, and D.H. Manicourt Effects of calcitonin on subchondral trabecular bone changes and on osteoarthritic cartilage lesions after acute anterior cruciate ligament deficiency J Bone Miner Res 19 2004 1821 1826
    • (2004) J Bone Miner Res , vol.19 , pp. 1821-1826
    • Behets, C.1    Williams, J.M.2    Chappard, D.3    Devogelaer, J.P.4    Manicourt, D.H.5
  • 40
    • 23944509471 scopus 로고    scopus 로고
    • Morphometric changes in the epiphyseal plate of the growing and young adult male rat after long-term salmon calcitonin administration
    • L. Khaldi, T. Karachalios, A. Galanos, and G.P. Lyritis Morphometric changes in the epiphyseal plate of the growing and young adult male rat after long-term salmon calcitonin administration Calcif Tissue Int 76 2005 426 432
    • (2005) Calcif Tissue Int , vol.76 , pp. 426-432
    • Khaldi, L.1    Karachalios, T.2    Galanos, A.3    Lyritis, G.P.4
  • 41
    • 84873492650 scopus 로고    scopus 로고
    • The calcitonin and glucocorticoids combination: Mechanistic insights into their class-effect synergy in experimental arthritis
    • A. Al-Kashi, T. Montero-Melendez, N. Moradi-Bidhendi, J.P. Gilligan, N. Mehta, and M. Perretti The calcitonin and glucocorticoids combination: mechanistic insights into their class-effect synergy in experimental arthritis PloS One 8 2013 e54299
    • (2013) PloS One , vol.8 , pp. e54299
    • Al-Kashi, A.1    Montero-Melendez, T.2    Moradi-Bidhendi, N.3    Gilligan, J.P.4    Mehta, N.5    Perretti, M.6
  • 42
    • 0025789157 scopus 로고
    • Induction of calcitonin receptor expression by glucocorticoids in T47D human breast cancer cells
    • M. Kurokawa, V.P. Michelangeli, and D.M. Findlay Induction of calcitonin receptor expression by glucocorticoids in T47D human breast cancer cells J Endocrinol 130 1991 321 326
    • (1991) J Endocrinol , vol.130 , pp. 321-326
    • Kurokawa, M.1    Michelangeli, V.P.2    Findlay, D.M.3
  • 43
    • 0029014779 scopus 로고
    • Homologous regulation of the calcitonin receptor in mouse osteoclast-like cells and human breast cancer T47D cells
    • S. Wada, T.J. Martin, and D.M. Findlay Homologous regulation of the calcitonin receptor in mouse osteoclast-like cells and human breast cancer T47D cells Endocrinology 136 1995 2611 2621
    • (1995) Endocrinology , vol.136 , pp. 2611-2621
    • Wada, S.1    Martin, T.J.2    Findlay, D.M.3
  • 44
    • 0031039823 scopus 로고    scopus 로고
    • Regulation by calcitonin and glucocorticoids of calcitonin receptor gene expression in mouse osteoclasts
    • S. Wada, N. Udagawa, T. Akatsu, N. Nagata, T.J. Martin, and D.M. Findlay Regulation by calcitonin and glucocorticoids of calcitonin receptor gene expression in mouse osteoclasts Endocrinology 138 1997 521 529
    • (1997) Endocrinology , vol.138 , pp. 521-529
    • Wada, S.1    Udagawa, N.2    Akatsu, T.3    Nagata, N.4    Martin, T.J.5    Findlay, D.M.6
  • 45
    • 0030891983 scopus 로고    scopus 로고
    • Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage
    • R.C. Billinghurst, L. Dahlberg, M. Ionescu, A. Reiner, R. Bourne, and C. Rorabeck Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage J Clin Invest 99 1997 1534 1545
    • (1997) J Clin Invest , vol.99 , pp. 1534-1545
    • Billinghurst, R.C.1    Dahlberg, L.2    Ionescu, M.3    Reiner, A.4    Bourne, R.5    Rorabeck, C.6
  • 47
    • 13844315153 scopus 로고    scopus 로고
    • Microarray analysis of proliferative and hypertrophic growth plate zones identifies differentiation markers and signal pathways
    • Y. Wang, F. Middleton, J.A. Horton, L. Reichel, C.E. Farnum, and T.A. Damron Microarray analysis of proliferative and hypertrophic growth plate zones identifies differentiation markers and signal pathways Bone 35 2004 1273 1293
    • (2004) Bone , vol.35 , pp. 1273-1293
    • Wang, Y.1    Middleton, F.2    Horton, J.A.3    Reichel, L.4    Farnum, C.E.5    Damron, T.A.6
  • 48
    • 84857138403 scopus 로고    scopus 로고
    • Chondrocyte hypertrophy and osteoarthritis: Role in initiation and progression of cartilage degeneration
    • P.M. van der Kraan, and W.B. van den Berg Chondrocyte hypertrophy and osteoarthritis: role in initiation and progression of cartilage degeneration Osteoarthr Cartil 20 2012 223 232
    • (2012) Osteoarthr Cartil , vol.20 , pp. 223-232
    • Van Der Kraan, P.M.1    Van Den Berg, W.B.2
  • 50
    • 15844413814 scopus 로고    scopus 로고
    • Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis
    • S.S. Glasson, R. Askew, B. Sheppard, B. Carito, T. Blanchet, and H.L. Ma Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis Nature 434 2005 644 648
    • (2005) Nature , vol.434 , pp. 644-648
    • Glasson, S.S.1    Askew, R.2    Sheppard, B.3    Carito, B.4    Blanchet, T.5    Ma, H.L.6
  • 52
    • 84874606888 scopus 로고    scopus 로고
    • Strontium ranelate reduces cartilage degeneration and subchondral bone remodeling in rat osteoarthritis model
    • D.G. Yu, H.F. Ding, Y.Q. Mao, M. Liu, B. Yu, and X. Zhao Strontium ranelate reduces cartilage degeneration and subchondral bone remodeling in rat osteoarthritis model Acta Pharmacol Sin 34 2013 393 402
    • (2013) Acta Pharmacol Sin , vol.34 , pp. 393-402
    • Yu, D.G.1    Ding, H.F.2    Mao, Y.Q.3    Liu, M.4    Yu, B.5    Zhao, X.6
  • 53
    • 84891746316 scopus 로고    scopus 로고
    • Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: Results of a double-blind randomised, placebo-controlled trial
    • J.Y. Reginster Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind randomised, placebo-controlled trial Ann Rheum Dis 73 2014 e8
    • (2014) Ann Rheum Dis , vol.73 , pp. e8
    • Reginster, J.Y.1
  • 54
    • 84891747397 scopus 로고    scopus 로고
    • The coupling of bone and cartilage turnover in osteoarthritis: Opportunities for bone antiresorptives and anabolics as potential treatments
    • M.A. Karsdal, A.C. Bay-Jensen, R.J. Lories, S. Abramson, T. Spector, and P. Pastoureau The coupling of bone and cartilage turnover in osteoarthritis: opportunities for bone antiresorptives and anabolics as potential treatments Ann Rheum Dis 73 2014 336 348
    • (2014) Ann Rheum Dis , vol.73 , pp. 336-348
    • Karsdal, M.A.1    Bay-Jensen, A.C.2    Lories, R.J.3    Abramson, S.4    Spector, T.5    Pastoureau, P.6
  • 55
    • 0026133097 scopus 로고
    • Cell cycle-dependent coupling of the calcitonin receptor to different G proteins
    • M. Chakraborty, D. Chatterjee, S. Kellokumpu, H. Rasmussen, and R. Baron Cell cycle-dependent coupling of the calcitonin receptor to different G proteins Science 251 1991 1078 1082
    • (1991) Science , vol.251 , pp. 1078-1082
    • Chakraborty, M.1    Chatterjee, D.2    Kellokumpu, S.3    Rasmussen, H.4    Baron, R.5
  • 56
    • 0031758253 scopus 로고    scopus 로고
    • Phospholipase D- and protein kinase C isoenzyme-dependent signal transduction pathways activated by the calcitonin receptor
    • F. Naro, M. Perez, S. Migliaccio, D.L. Galson, P. Orcel, and A. Teti Phospholipase D- and protein kinase C isoenzyme-dependent signal transduction pathways activated by the calcitonin receptor Endocrinology 139 1998 3241 3248
    • (1998) Endocrinology , vol.139 , pp. 3241-3248
    • Naro, F.1    Perez, M.2    Migliaccio, S.3    Galson, D.L.4    Orcel, P.5    Teti, A.6
  • 57
    • 0034127724 scopus 로고    scopus 로고
    • Cyclic AMP a key messenger in the regulation of skin pigmentation
    • R. Busca, and R. Ballotti Cyclic AMP a key messenger in the regulation of skin pigmentation Pigment Cell Res 13 2000 60 69
    • (2000) Pigment Cell Res , vol.13 , pp. 60-69
    • Busca, R.1    Ballotti, R.2
  • 58
    • 0020503814 scopus 로고
    • Forskolin: A labdane diterpenoid with antihypertensive, positive inotropic, platelet aggregation inhibitory, and adenylate cyclase activating properties
    • N.J. de Souza, A.N. Dohadwalla, and J. Reden Forskolin: a labdane diterpenoid with antihypertensive, positive inotropic, platelet aggregation inhibitory, and adenylate cyclase activating properties Med Res Rev 3 1983 201 219
    • (1983) Med Res Rev , vol.3 , pp. 201-219
    • De Souza, N.J.1    Dohadwalla, A.N.2    Reden, J.3
  • 59
    • 0031886742 scopus 로고    scopus 로고
    • Osteoarthritis chondrocytes die by apoptosis. A possible pathway for osteoarthritis pathology
    • F.J. Blanco, R. Guitian, E. Vazquez-Martul, F.J. de Toro, and F. Galdo Osteoarthritis chondrocytes die by apoptosis. A possible pathway for osteoarthritis pathology Arthritis Rheumatol 41 1998 284 289
    • (1998) Arthritis Rheumatol , vol.41 , pp. 284-289
    • Blanco, F.J.1    Guitian, R.2    Vazquez-Martul, E.3    De Toro, F.J.4    Galdo, F.5
  • 60
    • 0034190357 scopus 로고    scopus 로고
    • Inhibition of caspase-3-like activity prevents apoptosis while retaining functionality of human chondrocytes in vitro
    • M.E. Nuttall, D.P. Nadeau, P.W. Fisher, F. Wang, P.M. Keller, and W.E. DeWolf Jr. Inhibition of caspase-3-like activity prevents apoptosis while retaining functionality of human chondrocytes in vitro J Orthop Res 18 2000 356 363
    • (2000) J Orthop Res , vol.18 , pp. 356-363
    • Nuttall, M.E.1    Nadeau, D.P.2    Fisher, P.W.3    Wang, F.4    Keller, P.M.5    Dewolf, Jr.W.E.6
  • 61
    • 1042278739 scopus 로고    scopus 로고
    • Increased apoptosis in human osteoarthritic cartilage corresponds to reduced cell density and expression of caspase-3
    • M. Sharif, A. Whitehouse, P. Sharman, M. Perry, and M. Adams Increased apoptosis in human osteoarthritic cartilage corresponds to reduced cell density and expression of caspase-3 Arthritis Rheumatol 50 2004 507 515
    • (2004) Arthritis Rheumatol , vol.50 , pp. 507-515
    • Sharif, M.1    Whitehouse, A.2    Sharman, P.3    Perry, M.4    Adams, M.5
  • 63
    • 84872516767 scopus 로고    scopus 로고
    • The pathogenesis of osteoarthritis involves bone, cartilage and synovial inflammation: May estrogen be a magic bullet
    • M.A. Karsdal, A.C. Bay-Jensen, K. Henriksen, and C. Christiansen The pathogenesis of osteoarthritis involves bone, cartilage and synovial inflammation: may estrogen be a magic bullet Menopause Int 18 2012 139 146
    • (2012) Menopause Int , vol.18 , pp. 139-146
    • Karsdal, M.A.1    Bay-Jensen, A.C.2    Henriksen, K.3    Christiansen, C.4
  • 64
    • 36549027898 scopus 로고    scopus 로고
    • Calcitonin affects both bone and cartilage: A dual action treatment for osteoarthritis
    • M.A. Karsdal, B.C. Sondergaard, M. Arnold, and C. Christiansen Calcitonin affects both bone and cartilage: a dual action treatment for osteoarthritis Ann N Y Acad Sci 1117 2007 181 195
    • (2007) Ann N y Acad Sci , vol.1117 , pp. 181-195
    • Karsdal, M.A.1    Sondergaard, B.C.2    Arnold, M.3    Christiansen, C.4
  • 65
    • 34248569434 scopus 로고    scopus 로고
    • Induction of increased cAMP levels in articular chondrocytes blocks matrix metalloproteinase-mediated cartilage degradation, but not aggrecanase-mediated cartilage degradation
    • M.A. Karsdal, E.U. Sumer, H. Wulf, S.H. Madsen, C. Christiansen, and A.J. Fosang Induction of increased cAMP levels in articular chondrocytes blocks matrix metalloproteinase-mediated cartilage degradation, but not aggrecanase-mediated cartilage degradation Arthritis Rheumatol 56 2007 1549 1558
    • (2007) Arthritis Rheumatol , vol.56 , pp. 1549-1558
    • Karsdal, M.A.1    Sumer, E.U.2    Wulf, H.3    Madsen, S.H.4    Christiansen, C.5    Fosang, A.J.6
  • 67
    • 0034694895 scopus 로고    scopus 로고
    • Modulation of the effects of osteoprotegerin (OPG) ligand in a human leukemic cell line by OPG and calcitonin
    • L. Mancini, N. Moradi-Bidhendi, M.L. Brandi, M. Perretti, and I. MacIntyre Modulation of the effects of osteoprotegerin (OPG) ligand in a human leukemic cell line by OPG and calcitonin Biochem Biophys Res Commun 279 2000 391 397
    • (2000) Biochem Biophys Res Commun , vol.279 , pp. 391-397
    • Mancini, L.1    Moradi-Bidhendi, N.2    Brandi, M.L.3    Perretti, M.4    Macintyre, I.5
  • 68
    • 58149327054 scopus 로고    scopus 로고
    • Investigation of the diurnal variation in bone resorption for optimal drug delivery and efficacy in osteoporosis with oral calcitonin
    • M.A. Karsdal, I. Byrjalsen, B.J. Riis, and C. Christiansen Investigation of the diurnal variation in bone resorption for optimal drug delivery and efficacy in osteoporosis with oral calcitonin BMC Clin Pharmacol 8 2008 12
    • (2008) BMC Clin Pharmacol , vol.8 , pp. 12
    • Karsdal, M.A.1    Byrjalsen, I.2    Riis, B.J.3    Christiansen, C.4
  • 69
    • 84864127997 scopus 로고    scopus 로고
    • A phase 3 trial of the efficacy and safety of oral recombinant calcitonin: The Oral Calcitonin in Postmenopausal Osteoporosis (ORACAL) trial
    • N. Binkley, M. Bolognese, A. Sidorowicz-Bialynicka, T. Vally, R. Trout, and C. Miller A phase 3 trial of the efficacy and safety of oral recombinant calcitonin: the Oral Calcitonin in Postmenopausal Osteoporosis (ORACAL) trial J Bone Miner Res 27 2012 1821 1829
    • (2012) J Bone Miner Res , vol.27 , pp. 1821-1829
    • Binkley, N.1    Bolognese, M.2    Sidorowicz-Bialynicka, A.3    Vally, T.4    Trout, R.5    Miller, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.