Treatment with calcitonin prevents the net loss of collagen, hyaluronan and proteoglycan aggregates from cartilage in the early stages of canine experimental osteoarthritis

Osteoarthritis and Cartilage

Volumn 12, Issue 11, 2004, Pages 904-911

  El Hajjaji, Hafida ^a   Williams, James M ^b   Devogelaer, Jean Pierre ^c   Lenz, Mary Ellen ^b   Thonar, Eugene J M A ^b   Manicourt, Daniel Henri ^a,c  

^a DE DUVE INSTITUTE   (Belgium)

^b RUSH MEDICAL COLLEGE   (United States)

^c CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

Author keywords

Aggrecan; Calcitonin; Collagen; Hyaluronan; Keratan sulfate; Osteoarthritis

Indexed keywords

AGGRECAN; CALCITONIN; COLLAGEN; HYALURONIC ACID; KERATAN SULFATE; NOSE SPRAY; PLACEBO; PROTEOGLYCAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR CRUCIATE LIGAMENT RUPTURE; ARTICLE; ARTICULAR CARTILAGE; CONTROLLED STUDY; DENSITY GRADIENT CENTRIFUGATION; DISEASE SEVERITY; DOG; DOSE RESPONSE; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOPATHOLOGY; KNEE INJURY; KNEE INSTABILITY; KNEE OSTEOARTHRITIS; NONHUMAN; OSTEOPHYTE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEPLETION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; RANDOMIZATION; TISSUE DISTRIBUTION;

AGGRECANS; ANIMALS; ANTERIOR CRUCIATE LIGAMENT; CALCITONIN; CARTILAGE, ARTICULAR; CENTRIFUGATION, DENSITY GRADIENT; COLLAGEN; DOGS; EXTRACELLULAR MATRIX PROTEINS; HINDLIMB; HYALURONIC ACID; KERATAN SULFATE; LECTINS, C-TYPE; OSTEOARTHRITIS; PROTEOGLYCANS;

EID: 7744219600     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2004.08.005     Document Type: Article

References (36)

1. M.W. Lark E.K. Bayne J. Flanagan C.F. Harper L.A. Hoerrner N.I. Hutchinson et al. Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints J Clin Invest 100 1997 93-106
2. W. Wu R.C. Billinghurst I. Pidoux J. Antoniou D. Zukor M. Tanzer et al. Sites of collagenase cleavage and denaturation of type II collagen in aging and osteoarthritic articular cartilage and their relationship to the distribution of matrix metalloproteinase 1 and matrix metalloproteinase 13 Arthritis Rheum 46 2002 2087-2094
3. D.H. Manicourt O. Cornu M.E. Lenz A. Druetz-Van Egeren E.J.-M.A. Thonar Rapid and sustained rise in the serum level of hyaluronan after anterior cruciate ligament transection in the dog knee joint J Rheumatol 22 1995 262-269
4. M. Sharif E. George L. Shepstone W. Knudson E.J.-M.A. Thonar J. Cushnaghan et al. Serum hyaluronic acid level as a predictor of disease progression in osteoarthritis of the knee Arthritis Rheum 38 1995 760-767
5. P. Dieppe J. Cushnaghan P. Young J. Kirwan Prediction of the progression of joint space narrowing in osteoarthritis of the knee by bone scintigraphy Ann Rheum Dis 52 1993 557-563
6. M. Sharif E. George P.A. Dieppe Correlation between synovial fluid markers of cartilage and bone turnover and scintigraphic scan abnormalities in osteoarthritis of the knee Arthritis Rheum 38 1995 78-81
7. C.A. McDevitt E.M.M. Gilbertson H. Muir An experimental model of osteoarthritis: Early morphological and biochemical changes J Bone Joint Surg 59B 1977 24-35
8. K.D. Brandt E.M. Braumstein D.M. Visco B. O'Connor B.D. Heck M. Albrecht Anterior (cranial) cruciate ligament transection in the dog: A bona fide model of canine osteoarthritis, not merely of cartilage injury and repair J Rheumatol 18 1991 436-446
9. D.H. Manicourt J.C. Pita Progressive depletion of hyaluronic acid in early experimental osteoarthritis in dogs Arthritis Rheum 31 1988 538-544
10. D.H. Manicourt E.J.-M.A. Thonar J.C. Pita D.S. Howell Changes in the sedimentation profile of proteoglycan aggregates in early experimental canine osteoarthritis Connect Tissue Res 23 1989 33-50
11. F.J. Muller L.A. Setton D.H. Manicourt V.C. Mow D.S. Howell J.C. Pita Centrifugal and biochemical comparison of proteoglycan aggregates from articular cartilage in experimental joint disuse and joint instability J Orthop Res 12 1994 498-508
12. M.B. Sweet E.J.-M.A. Thonar A.R. Immelman L. Solomon Biochemical changes in progressive osteoarthrosis Ann Rheum Dis 36 1977 387-398
13. F.J. Muller J.C. Pita D.H. Manicourt T.I. Malinin J.M. Schoonbeck V.C. Mow Centrifugal characterization of proteoglycans from various depth layers and weight-bearing areas of normal and abnormal human articular cartilage J Orthop Res 7 1989 326-334
14. D.H. Manicourt R.D. Altman J.M. Williams J.-P. Devogelaer A. Druetz-Van Egeren M.E. Lenz et al. Treatment with calcitonin suppresses the responses of bone, cartilage, and synovium in the early stages of canine experimental osteoarthritis and significantly reduces the severity of the cartilage lesions Arthritis Rheum 42 1999 1159-1167
15. H.J. Mankin H. Dorfman L. Lipiello A. Zarina Biochemical and metabolic abnormalities in articular cartilage from osteoarthritic human hips. II Correlation of morphology with biochemical and metabolic data J Bone Joint Surg 53 1971 523-537
16. J.F. Woessner Jr. The determination of hydroxyproline in tissue and protein samples containing a small portion of this amino acid Arch Biochem Biophys 93 1961 440-447
17. S. Chandrasekhar M.A. Esterman H.A. Hoffman Microdetermination of proteoglycans and glycosaminoglycans in the presence of guanidine hydrochloride Anal Biochem 161 1987 103-108
18. E.J.-M.A. Thonar M.E. Lenz G.K. Klintworth B. Caterson L.M. Pachman P. Glickman et al. Quantification of keratan sulfate in blood as a marker of cartilage catabolism Arthritis Rheum 28 1985 1367-1376
19. X.Q. Li E.J.-M.A. Thonar W. Knudson Accumulation of hyaluronate in human lung carcinoma as measured by a new hyaluronate ELISA Connect Tissue Res 19 1989 243-253
20. D.H. Manicourt J.C. Pita C.F. Pezon D.S. Howell Characterization of the proteoglycans recovered under non-dissociative conditions from normal cartilage of rabbits and dogs J Biol Chem 261 1986 5426-5433
21. J.C. Pita F.J. Muller T. Oegema V.C. Hascall Determination of sedimentation coefficient distributions for cartilage proteoglycans Arch Biochem Biophys 186 1978 66-76
22. A. Maroudas Balance between swelling pressure and collagen tension in normal and degenerate cartilage Nature 260 1976 808-809
23. M.E. Adams K.D. Brandt Hypertrophic repair of canine articular cartilage in osteoarthritis after anterior cruciate ligament transection J Rheumatol 18 1991 428-435
24. J.R. Matyas D. Huang M. Chung M.E. Adams Regional quantification of cartilage type II collagen and aggrecan messenger RNA in joints with early experimental osteoarthritis Arthritis Rheum 46 2002 1536-1543
25. P. Franchimont C. Bassleer Y. Henrotin P. Gysen R. Bassleer Effects of human and salmon calcitonin on human articular chondrocytes cultivated in clusters J Clin Endocrinol Metab 69 1989 259-266
26. A.R. Poole D.S. Howell Etiopathogenesis of osteoarthritis. In: R.W. Moskowitz D.S. Howell R.D. Altman J.A. Buckwalter V.M. Goldberg (Eds.). Osteoarthritis: Diagnosis and Medical/Surgical Management 2001 WB Saunders Company Philadelphia 29-47
27. M.P. Hellio M.J. Peschard C. Cohen M. Richar E. Vignon Calcitonin inhibits phospholipase A2 and collagenase activity of human osteoarthritic chondrocytes Osteoarthritis Cartilage 5 1997 121-128
28. C.I. Westacott G.R. Webb M.G. Warnock J.V. Sims C.J. Elson Alteration of cartilage metabolism by cells from osteoarthritic bone Arthritis Rheum 40 1997 1282-1291
29. V.C. Mow L.A. Setton A. Ratcliffe D.S. Howell J.A. Buckwalter Structure-function relationships of articular cartilage and the effects of joint instability and trauma on cartilage function. In: K.D. Brandt (Ed.). Cartilage Changes in Osteoarthritis 1990 Indiana University School of Medicine Indianapolis 22-42
30. F. Guilak A. Ratcliffe N. Lane M.P. Rosenwasser V.C. Mow Mechanical and biochemical changes in the superficial zone of articular cartilage in canine experimental osteoarthritis J Orthop Res 12 1994 474-484
31. T.E. Hardingham H. Muir M.K. Kwan W.M. Lai V.C. Mow Viscoelastic properties of proteoglycan solutions with varying proportions present as aggregates J Orthop Res 5 1987 36-46
32. J. Ryu B.V. Treadwell H.J. Mankin Biochemical and metabolic abnormalities in normal and osteoarthritic human articular cartilage Arthritis Rheum 27 1984 49-57
33. D.H. Manicourt A. Druetz-Van Egeren L. Haazen C. Nagant de Deuxchaisnes Effects of tenoxicam and aspirin on the metabolism of proteoglycans and hyaluronan in normal and osteoarthritic human articular cartilage Br J Pharmacol 113 1994 1113-1120
34. Q. Hua C.B. Knudson W. Knudson Internalization of hyaluronan by chondrocytes via receptor-mediated endocytosis J Cell Sci 106 1993 365-375
35. Q. Chu M. Lopez K. Hayashi M. Ionescu R.C. Billinghurst K.A. Johnson et al. Elevation of a collagenase generated type II collagen neoepitope and proteoglycan epitopes in synovial fluid following induction of joint instability in the dog Osteoarthritis Cartilage 10 2002 662-669
36. W. Wu R.C. Billinghurst I. Pidoux J. Antoniou D. Zukor M. Tanzer et al. Sites of collagenase cleavage and denaturation of type II collagen in aging and osteoarthritic articular cartilage and their relationship to the distribution of matrix metalloproteinase 1 and matrix metalloproteinase 13 Arthritis Rheum 46 2002 2087-2094