Regulation by calcitonin and glucocorticoids of calcitonin receptor gene expression in mouse osteoclasts

Endocrinology

Volumn 138, Issue 2, 1997, Pages 521-529

  Wada, Seiki ^a,b   Udagawa, Nobuyuki ^a,c   Akatsu, Takuhiko ^b   Nagata, Naokazu ^b   Martin, T John ^a   Findlay, David M ^a,d,e  

^a ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d Natl Hlth Med Res Cncl A   (Australia)

^e ROYAL ADELAIDE HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

5,6 DICHLOROBENZIMIDAZOLE RIBOSIDE; ADENYLATE CYCLASE; CALCITONIN; CALCITONIN RECEPTOR; DEXAMETHASONE; GLUCOCORTICOID; MESSENGER RNA;

ADOLESCENT; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HORMONAL REGULATION; MALE; MOUSE; NEWBORN; NONHUMAN; OSTEOCLAST; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR DENSITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION;

EID: 0031039823     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.138.2.4905     Document Type: Article

References (48)

1. Wener JA, Gorton SJ, Raisz LG 1972 Escape from inhibition of resorption in cultures of fetal bone treated with calcitonin and parathyroid hormone. Endocrinology 90:752-759
2. Silva OL, Becker KL 1973 Salmon calcitonin in the treatment of hypercalcemia. Arch Intern Med 132:337-339
3. Binstock ML, Mundy GR 1980 Effect of calcitonin and glucocorticoids in combination on the hypercalcemia of malignancy. Ann Intern Med 93:269-272
4. Kimura S, Sato Y, Matsubara H, Adachi I, Yamaguchi K, Suzuki M, Suemasu K, Abe K 1986 A retrospective evaluation of the medical treatment of malignancy-associated hypercalcemia. Jpn J Cancer Res 77:85-91
5. Tobias J, Chambers T 1989 Glucocorticoids impair bone resorptive activity and viability of osteoclasts disaggregated from neonatal rat long bones. Lancet 23:900-901
6. Raisz LG, Trummel CL, Wener JA, Simmons H 1972 Effect of glucocorticoids on bone resorption in tissue culture. Endocrinology 90:961-967
7. Wada S, Akatsu T, Tamura T, Takahashi N, Suda T, Nagata N 1994 Glucocorticoid regulation of calcitonin receptor in mouse osteoclast-like multinucleated cells. J Bone Miner Res 9:1705-1712
8. Yamin M, Gorn AH, Flannery MR, Jenkins NA, Gilber DJ, Copeland NG, Tapp DR, Krane SM, Goldring SR 1994 Cloning and characterization of a mouse brain calcitonin receptor complementary deoxyribonucleic acid and mapping of the calcitonin receptor gene. Endocrinology 135:2635-2643
9. Sexton PM, Houssami S, Hilton JM, O'Keeffe LM, Center RJ, Gillespie MT, Darcy P, Findlay DM 1993 Identification of brain isoforms of the rat calcitonin receptor. Mol Endocrinol 7:815-821
10. Gorn AH, Lin HY, Yamin M, Auron PE, Flannery MR, Tapp DR, Manning CA, Lodish HF, Krane SM, Goldring SR 1992 Cloning, characterization, and expression of a human calcitonin receptor from an ovarian carcinoma cell line. J Clin Invest 90:1726-1735
11. Lin HY, Harris TL, Flannery MS, Aruffo A, Kaji EH, Gorn A, Kolakowski Jr LF, Lodish HF, Goldring SR 1991 Expression cloning of an adenylate cyclase-coupled calcitonin receptor. Science 254:1022-1024
12. Wada S, Martin TJ, Findlay DM 1995 Homologous regulation of the calcitonin receptor in mouse osteoclast-like cells and human breast cancer T47D cells. Endocrinology 136:2611-2621
13. Ikegame M, Rakopoulos M, Zhou H, Houssami S, Martin TJ, Mosely JM, Findlay DM 1995 Calcitonin receptor isoforms in mouse and rat osteoclasts. J Bone Miner Res 10:59-65
14. Lee SK, Goldring SR, Lorenzo JA 1995 Expression of the calcitonin receptor in bone marrow cell cultures and in bone: a specific marker of the differentiated osteoclast that is regulated by calcitonin. Endocrinology 136:4572-4581
15. Takahashi S, Goldring SR, Katz M, Hilsenbeck S, Williams R, Roodman GD 1995 Down-regulation of calcitonin receptor mRNA expression by calcitonin during human osteoclast-like cell differentiation. J Clin Invest 95:167-171
16. Wada S, Udagawa N, Nagata N, Martin TJ, Findlay DM 1996 Physiological levels of calcitonin regulate the mouse osteoclast calcitonin receptor by a protein kinase A-mediated mechanism. Endocrinology 137:312-320
17. Hadcock JR, Malbon CC 1988 Down-regulation of β-adrenergic receptors: agonist-induced reduction in receptor mRNA levels. Proc Natl Acad Sci USA 85:5021-5025
18. Atwater JA, Wisdom R, Verma IM 1990 Regulated mRNA stability. Annu Rev Genet 24:519-541
19. r 35,000 protein(s) that selectively binds to β-adrenergic receptor mRNAs. J Biol Chem 267:24103-24108
20. r 35,000 β-adrenergic receptor mRN A-binding protein binds transcripts of G-protein-linked receptors which undergo agonist-induced destabilization. J Biol Chem 270:12787-12793
21. Pende A, Tremmel KD, DeMaria CT, Blaxall BC, Minobe WA, Sherman JA, Bisognano JD, Bristow MR, Brewer G, Port JD 1996 Regulation of the mRNA-binding protein AUF1 by activation of the β-adrenergic receptor signal transduction pathway. J Biol Chem 271:8493-8501
22. Akatsu T, Tamura T, Takahashi N, Udagawa N, Tanaka S, Sasaki T, Yamaguchi A, Nagata N, Suda T 1992 Preparation and characterization of a mouse osteoclast-like multinucleated cell population. J Bone Miner Res 7:1297-1306
23. Tamura T, Takahashi N, Akatsu T, Sasaki T, Udagawa N, Tanaka S, Suda T 1993 New resorption assay with mouse osteoclast-like multinucleated cells formed in vitro. J Bone Miner Res 8:953-960
24. Wada S, Yasutomo Y, Kosano H, Kugai N, Nagata N 1991 The effect of PGF2α on parathyroid hormone-stimulated cyclic AMP production in mouse osteoblastic cell, MC3T3E1. Biochim Biophys Acta 1074:182-188
25. Chomezynski P, Sacchi N 1987 Single step method of RNA isolation by guanidinium thiocyanate-phenol chloroform extraction. Anal Biochem 162:156-159
26. Wada S, Udagawa N, Nagata N, Martin TJ, Findlay DM 1996 Calcitonin receptor down-regulation relates to calcitonin resistance in mature mouse osteoclasts. Endocrinology 137:1042-1048
27. Tso JY, Sun XH, Kao TH, Reece KS, Wu R 1985 Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene. Nucleic Acids Res 13:2485-2502
28. Zhou H, Manji S, Findlay DM, Martin TJ, Heath J, Ng KW 1994 Novel action of retinoic acid: stabilization of newly-synthesized alkaline phosphatase transcripts. J Biol Chem 269:22433-22439
29. Manji S, Zhou H, Findlay DM, Martin TJ, Ng KW 1994 Tumor necrosis factor-a facilitates nuclear actions of retinoic acid to regulate nuclear actions of retinoic acid to regulate expression of the alkaline phosphatase gene in preosteoblasts. J Biol Chem 270:8958-8962
30. Rakopoulos M, Ikegame M, Findlay DM, Martin TJ, Moseley JM 1995 Short treatment of osteoclasts in bone marrow culture with calcitonin causes prolonged suppression of calcitonin receptor mRNA. Bone 17:447-453
31. Hadcock JR, Wang H-Y, Malbon CC 1989 Agonist-induced destabilization of β-adrenergic receptor mRNA. Attenuation of glucocorticoid-induced up-regulation of β-adrenergic receptors. J Biol Chem 264:19928-19933
32. Chen C-YA, Xu N, Shyu A-B 1995 mRNA decay mediated by two distinct AU-rich elements from c-fos and granulocyte-macrophage colony-stimulating factor transcripts: different deadenylation kinetics and uncoupling from translation. Mol Cell Biol 15:5777-5788
33. Nair APK, Hahn S, Banholzer R, Hirsch HH, Moroni C 1994 Cyclosporin A inhibits growth of autocrine tumour cell lines by destabilizing interleukin-3 mRNA. Nature 369:239-242
34. Jones TR, Cole MD 1987 Rapid cytoplasmic turnover of c-myc mRNA: requirement of the 3′ untranslated sequences. Mol Cell Biol 7:4513-4521
35. Schiavi SC, Wellington CL, Shyu A-B, Chen C-YA, Greenberg ME, Belasco JG 1994 Multiple elements in the c-fos protein-coding region facilitate mRNA deadenylation and decay by a mechanism coupled to translation. J Biol Chem 269:3441-3448
36. Chen C-YA, Chen T-M, Shyu A-B 1994 Interplay of two functionally and structurally distinct domains of the C-fos AU-rich element specifies its mRNA-destabilizing function. Mol Cell Biol 14:416-426
37. Salehi-Ashtiani K, Goldberg E 1995 Posttranslation regulation of primate Ldhc mRNA by its AUUUA-like elements. Mol Endocrinol 9:1782-1790
38. Lagnado CA, Brown CY, Goodall GJ 1994 AUUUA is not sufficient to promote poly(A) shortening and degradation of an mRNA: the functional sequence within AU-rich elements may be UUAUUUA(U/A)(U/A). Mol Cell Biol 14:7984-7995
39. Zhang W, Wagner BJ, Ehrenman K, Schaefer AW, DeMaria CT, Crater D, Dehaven K, Long L, Brewer G 1993 Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1. Mol Cell Biol 13:7652-7665
40. Bohjanen PR, Petryniak B, June CH, Thompson CB, Lindsten T 1991 An inducible cytoplasmic factor (AU-B) binds selectively to AUUUA multimers in the 3′ untranslated region of lymphokine mRNA. Mol Cell Biol 11:3288-3295
41. Vakalopoulou E, Schaack J, Shenk T 1991 A 32-kilodalton protein binds to AU-rich domains in the 3′ untranslated regions of rapidly degraded mRNAs. Mol Cell Biol 11:3355-3364
42. Brewer G 1991 An A+U-rich element RNA-binding factor regulates c-myc mRNA stability in vitro. Mol Cell Biol 11:2460-2466
43. Findlay DM, Houssami S, Christopoulos G, Sexton PM, Homologous regulation of the rat C1a calcitonin receptor (CTR) in non-osteoclastic cells is independent of CTR mRNA changes and cyclic AMP-dependent protein kinase A activation. Endocrinology, in press
44. Whittemore L-A, Maniatis T 1990 Postinduction turnoff of beta-interferon gene expression. Mol Cell Biol 10:1329-1337
45. Ahern SM, Miyata T, Sadler JE 1993 Regulation of human tissue factor expression by mRNA turnover. J Biol Chem 268:2154-2159
46. Jimi E, Shuto T, Koga T 1995 Macrophage colony-stimulating factor and interleukin-1α maintain the survival of osteoclast-like cells. Endocrinology 136:808-811
47. Udagawa N, Takahashi N, Katagiri T, Tamura T, Wada S, Findlay DM, Martin TJ, Hirota H, Taga T, Kishimoto T, Suda T 1995 Interleukin 6 (IL-6) induction of osteoclast differentiation depends upon IL-6 receptors expressed on osteoblastic cell, but not on osteoclast progenitors. J Exp Med 182:1461-1468
48. Zolnierowicz S, Cron P, Solinas-Toldo S, Fries R, Lin HY, Hemmings BA 1994 Isolation, characterization, and chromosomal localization of the porcine calcitonin receptor gene. Identification of two variants of the receptor generated by alternative splicing. J Biol Chem 269:19530-19538